Clinical trials: Coronary Syndrome, Acute
Sleep Disturbance, Insomnia
The SleepWell Study - Chronotherapeutic Intervention to Improve Sleep Following ACS
This two-phase pilot study will test the feasibility of a "combined chronotherapy" (CC) intervention consisting of morning bright light therapy (BLT) and evening blue light blocking (BLB), administered daily for 4 weeks in…
- Conditions
- Sleep Disturbance, Insomnia, Acute Coronary Syndrome
- Trial name
- NCT05299723
- Testing
- BLT Intervention, BLB Intervention, Sleep Hygiene Education
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Columbia University
Acute Coronary Syndrome, Racial Bias
Ethnic Differences in Acute Coronary Syndromes Care in Emergency Departments.
When doctors and nurses use accepted guidelines for quickly treating patients who come to the emergency department (ED) with a possible heart attack, patients do better.
- Trial name
- ASCEND (NCT03463603)
- Where
- 3 sites in Canada
- Volunteers
- 448 people
- Sponsor
- University of British Columbia
Stable Angina, Unstable Angina
Safety and Effectiveness Evaluation of COBRA PzF Coronary Stent System: A Post Marketing Observational Registry
A multi-center, prospective, consecutive enrolled, observational registry. The population being studied includes all patients undergoing treatment of "de novo" lesions in native coronary vessels, saphenous vein graft and/or…
- Conditions
- Stable Angina, Unstable Angina, ACS - Acute Coronary Syndrome, STEMI
- Trial name
- eCOBRA (NCT03103620)
- Testing
- COBRA PzF Coronary Stent System
- Where
- 18 sites in France
- Volunteers
- 1,027 people
- Sponsor
- CeloNova BioSciences, Inc.
Acute Coronary Syndrome, Tobacco Use
Integrated Smoking Cessation and Mood Management for ACS Patients
Quitting smoking following acute coronary syndrome can reduce mortality up to 50%. However, depression and smoking are highly co-morbid and depressed mood may interfere with cessation and independently predicts mortality.
- Trial name
- PACES (NCT03029923)
- Testing
- Experimental: Behavioral Activation Treatment for Cardiac Smokers (BAT-CS), Smoking cessation plus Health and Wellness
- Where
- United States
- Sponsor
- The Miriam Hospital
Type 2 Diabetes Mellitus, Acute Coronary Syndrome
Assessment of Thrombogenicity in Acute Coronary Syndrome
The purpose of this study is to assess platelet dependent thrombogenicity in patients after acute coronary syndrome using an ex vivo arterial injury model.
- Trial name
- NCT00728286
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Acute Coronary Syndromes
Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN)
In order to further clarify the interaction of PPIs with clopidogrel anti - platelet effect , the investigators designed a clinical randomized controlled trials of omeprazole and pantoprazole antiplatelet effect of clopidogrel…
- Trial name
- NCT01735227
- Testing
- omeprazole, Pantoprazole
- Where
- 2 sites in China
- Volunteers
- 620 people
- Sponsor
- Yaling Han
Acute Coronary Syndrome
Central Apnea in Patients Receiving Ticagrelor
all patients with a left ventricular ejection fraction superior or equal to 50% less than 2 years after an acute coronary event and receiving ticagrelor will undergo a sleep polygraphy
- Trial name
- NCT03540459
- Testing
- sleep polygraphy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Les Grands Prés
Acute Coronary Syndromes
An Epidemiological Study of Acute Coronary Syndromes in The Greek Population. The TARGET Study
This is a multicenter, 2-phase observational study of acute coronary syndromes (ACS) in Greece, designed to provide real world data on the risk factors of patients presenting to a hospital emergency department with an index…
- Trial name
- TARGET (NCT01061086)
- Where
- 11 sites in Greece
- Volunteers
- 418 people
- Sponsor
- AstraZeneca
Cardiovascular Diseases, Acute Myocardial Infarction
Biomarkers Predicting Acute Myocardial Infraction in Patients Without Standard Modifiable Risk Factors
Coronary heart disease (CHD) is the leading cause of mortality worldwide. Every year, millions of people suffer its most adverse manifestation, an acute myocardial infraction (AMI).
- Conditions
- Cardiovascular Diseases, Acute Myocardial Infarction, Acute Coronary Syndrome, Metabolic Disturbance
- Trial name
- BeyondSMuRFs (NCT05535582)
- Testing
- Investigation of clinical, laboratory and imaging profile
- Where
- Greece
- Volunteers
- 1,000 people
- Sponsor
- Aristotle University Of Thessaloniki
ST Elevation Myocardial Infarction, Non ST Segment Elevation Acute Coronary Syndrome
ANalgesic Efficacy and Safety of MOrphiNe Versus Methoxyflurane in Patients With Acute Myocardial Infarction
The purpose of this study is to evaluate analgesic efficacy of inhaled methoxyflurane vs intravenous morphine in patients presenting with acute ST-elevation (STEMI) / non ST-elevation acute coronary syndrome (NSTE-ACS)
- Trial name
- ANEMON (NCT04476173)
- Testing
- Methoxyflurane - Penthrox, Morphine
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Acute Coronary Syndrome
Clinical Study on the Intervention of Xuesaitong Soft Capsules in Post-Intervention Patients with Acute Coronary Syndrome and Clinical Research Protocol
To assess the effects of Xuesaitong soft capsules on platelet function, clinical efficacy, prognosis, and safety in the treatment of acute coronary syndrome, 400 patients with acute coronary syndrome who underwent PCI were…
- Trial name
- NCT06845254
- Testing
- Xuesaitong soft capsule (main ingredient is Panax notoginseng saponins)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Acute Coronary Syndrome (ACS)
Improving Medication Adherence Through Graphically Enhanced Interventions in Acute Coronary Syndromes
Coronary heart disease (CHD) is the leading cause of death in the United States. Most people who die from CHD die of a heart attack.
- Trial name
- IMAGE-ACS (NCT00399880)
- Testing
- Health literacy intervention
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Vanderbilt University Medical Center
Chest Pain
Coronary Computed Tomography (CT) Angiography Versus Standard Therapy in the Emergency Room
The purpose of this study is to determine the usefulness of CCTA (Coronary Computed Tomography Angiography) in the emergency room setting to diagnose and predict the outcome of patients with chest pain who have a low to moderate…
- Trial name
- NCT00846469
- Testing
- CCTA (coronary computed tomography angiography), Control section
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Michigan
Coronary Artery Disease, Acute Coronary Syndrome
Genotyping Infarct Patients to Adjust and Normalize Thienopyridine Treatment
The objective of GIANT Study is to evaluate the clinical impact of genetic resistance to thienopyridine profile determination (CYP2C19 gene) and the clinical impact of compliance to an adjusted thienopyridine treatment on STEMI…
- Conditions
- Coronary Artery Disease, Acute Coronary Syndrome, Genetic Resistance to Clopidogrel, Compliance to Thienopyridine Treatment
- Trial name
- GIANT (NCT01134380)
- Where
- 12 sites in France
- Volunteers
- 1,500 people
- Sponsor
- Biotronik France
Acute Coronary Syndrome, Chest Pain
Database of Patients Undergoing Cardiac Computed Tomographic Angiography at William Beaumont Hospital (CT DATABASE)
The purpose of the study is to establish an overarching database of information containing historical, demographical, clinical, and intermediate and long-term outcome data from all William Beaumont Hospital (WBH) patients…
- Trial name
- CTDATABASE (NCT00922662)
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Kavitha Chinnaiyan
Acute Myocardial Infarction, Coronary Artery Disease
Myocardial Infarction, COmbined-device, Recovery Enhancement Study
Unplanned readmissions after hospitalization for acute myocardial infarction (AMI) are among the leading causes of preventable morbidity, mortality, and healthcare costs.
- Conditions
- Acute Myocardial Infarction, Coronary Artery Disease, Acute Coronary Syndrome, Myocardial Infarction
- Trial name
- MiCORE (NCT03760796)
- Testing
- Corrie Health Digital Platform
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University
Acute Coronary Syndrome, Atrial Fibrillation
Escalated Single Platelet Inhibition for One Month Plus NOAC in Patients With Atrial Fibrillation and ACS Undergoing PCI
The selection of the optimal antithrombotic therapy in patients with nonvalvular atrial fibrillation (AF) and acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) is challenging.
- Trial name
- EPIDAURUS (NCT04981041)
- Testing
- Prasugrel or Ticagrelor, Clopidogrel
- Where
- 37 sites in Austria, Germany
- Volunteers
- 602 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Acute Coronary Syndrome, Myocardial Infarction
Clopidogrel Reloading in Patients With NSTEACS Undergoing Percutaneous Coronary Intervention on Chronic Clopidogrel Therapy
Patients who developed an acute coronary syndrome despite dual antiplatelet therapy with aspirin and clopidogrel may benefit from a further dose of clopidogrel before a percutaneous coronary intervention.
- Trial name
- NCT01572129
- Testing
- Clopidogrel
- Where
- 2 sites in Italy
- Volunteers
- 240 people
- Sponsor
- Campus Bio-Medico University
Acute Coronary Syndromes (ACS)
Evaluation Through Innovative Examinations of Intestinal Dysbiosis Status in Patients Diagnosed With Cardiovascular Diseases and Evaluation of the Efficacy of Natural and Probiotic Extracts in the Non-pharmacological Approach to Improving Intestinal Dysbiosis Status.
The prospective experimental study aims to take an instantaneous photograph of the subject at time T0 and after 24 hours of intestinal permeability and dysbiosis indices in patients with acute coronary syndromes (ACS) which…
- Trial name
- DISBIO (NCT07429227)
- Testing
- Tea tree (Melaleuca alternifolia), Cinnamon (Cynnamomum zeylanicum) bark, Clove carnation (Eugenia caryopyllus) flowers, Red thyme (Thymus vulgaris) plant
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Long Covid19, Autonomic Dysfunction
Autonomic Nervous System Affection Due to Post Covid Syndrome
Post-Covid syndrome is defined as symptoms that develop in addition to respiratory symptoms in individuals who have had Covid-19 infection for more than 12 weeks.
- Trial name
- NCT05502094
- Testing
- Heart Rate Variability Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
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