Clinical trials: Coronary Artery Bypass Graft (CABG), open to volunteers
Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)
Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting.
This randomized, double-blind clinical trial aims to evaluate the impact of photobiomodulation therapy on postoperative outcomes in patients undergoing coronary artery bypass grafting (CABG).
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Graft (CABG), Surgical Wound Healing
- Trial name
- PHOTON (NCT07699679)
- Testing
- Photobiomodulation Therapy, Conventional Saphenous Vein Harvesting, No-Touch Saphenous Vein Harvesting
- Where
- Brazil
- Volunteers
- 292 people
- Sponsor
- Federal University of São Paulo
Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)
Hyperpolarized 13C Pyruvate-MRI and FDG-PET in a Single Exam for the Prognosis of Ischemic Cardiomyopathy
This prospective, non-blinded, single-center, translational research study aims to validate a multimodal advanced imaging exam for cardiac viability.
- Trial name
- FDG PET-HP MRI (NCT06814587)
- Testing
- Hyperpolarized 13C Pyruvate Magnetic Resonance Imaging (HP-13C MRI), [¹⁸F]Fluorodeoxyglucose Positron Emission Tomography (FDG-PET), SPECT MPI (Single Photon Emission Computed Tomography Myocardial Perfusion Imaging)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Frailty, Coronary Artery Disease
Funcional Recovery After Minithoracotomy or Sternotomy for CABG in Frail Patients
Frailty is a major predictor of adverse outcomes following coronary artery bypass grafting (CABG), being associated with increased postoperative complications, prolonged hospitalization, delayed functional recovery, and reduced…
- Conditions
- Frailty, Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)
- Trial name
- MINIFRAGILE (NCT07742475)
- Testing
- Minimally Invasive Coronary Artery Bypass Grafting (MICS-CABG), Conventional Coronary Artery Bypass Grafting (Median Sternotomy)
- Volunteers
- 194 people
- Sponsor
- University of Sao Paulo General Hospital
Acute Myocardial Infarction (AMI), Percutaneous Coronary Intervention (PCI)
BRIDGE Trial: Embedding Consumer-grade mHealth Technologies Into Cardiac Rehabilitation
The purpose of the BRIDGE study is to learn whether supplementing traditional center-based cardiac rehabilitation (CBCR) with a mobile health technology intervention can help patients monitor their health, stay engaged in healthy…
- Conditions
- Acute Myocardial Infarction (AMI), Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Graft Surgery (CABG), Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)
- Trial name
- BRIDGE (NCT07741396)
- Testing
- CBCR, BRIDGE mHealth intervention
- Volunteers
- 30 people
- Sponsor
- University of Illinois at Chicago
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery(CABG)
A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length Of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery.
EA-230 is a new therapy that may help people recover faster and have fewer problems after bypass surgery. In an earlier clinical trial, participants who received EA-230 during Coronary Artery Bypass surgery stayed in the…
- Trial name
- EasyBoost (NCT07357675)
- Testing
- EA-230 90mg/kg/hour
- Where
- 6 sites in United States, Belgium and 2 more
- Volunteers
- 300 people
- Sponsor
- EBI Anti Sepsis BV
Coronary Artery Bypass Graft (CABG), Chest Tubes
Chest Tube-Delivered Bupivacaine to Decrease Postoperative Pain After Cardiac Surgery
Background: After heart surgery, patients require temporary chest tubes - plastic drains placed inside the chest to prevent fluid building up around the heart and lungs.
- Conditions
- Coronary Artery Bypass Graft (CABG), Chest Tubes, Post Operative Pain Control
- Trial name
- FREEZE-B (NCT07643506)
- Testing
- 0.5% Bupivacaine without epinephrine, 10cc injection of normal saline (0.9%)
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Postoperative Pulmonary Complications, Coronary Artery Bypass Graft Surgery (CABG)
Mechanical Power and Pulmonary Complications in CABG Surgery
This prospective observational study evaluates the association between intraoperative mechanical power (MP) - a composite measure of the total energy delivered to the lungs during mechanical ventilation - and postoperative…
- Conditions
- Postoperative Pulmonary Complications, Coronary Artery Bypass Graft Surgery (CABG), Prolonged Mechanical Ventilation
- Trial name
- MP-CABG (NCT07639489)
- Testing
- Intraoperative Mechanical Ventilation Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Fusun Gozen
Coronary Artery Bypass, Graft Failure
Graft Failure and Consequences of Coronary Artery Bypass Graft Surgery
Coronary artery bypass graft (CABG) surgery is the commonest type of heart operation performed. During this, arteries or veins (termed 'grafts') are used to supply blood around blockages within the blood vessels that supply the…
- Conditions
- Coronary Artery Bypass, Graft Failure, Coronary Artery Bypass Graft, Coronary Artery Bypass Graft Surgery (CABG)
- Trial name
- NCT06800430
- Testing
- Hybrid [18F]-GP1, [68Ga]-DOTATATE, [68Ga]-FAPI total-body positron emission tomography and coronary computed tomography coronary angiography
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University of Edinburgh
Coronary Artery Bypass Graft (CABG)
Aortic No-Touch vs Partial Aortic Clamping in Off-Pump CABG
To explore surgical strategies that reduce perioperative neurologic complications in cardiovascular surgery, with the aim of improving perioperative outcomes and quality of life while reducing the socioeconomic burden.
- Trial name
- PROTECT-CABG (NCT07302659)
- Testing
- Aortic no-touch coronary artery bypass grafting (RIMA-SVG), Conventional off-pump CABG with partial clamping of the ascending aorta (Ao-SVG)
- Where
- 4 sites in China
- Volunteers
- 380 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Bypass Graft Surgery (CABG), Patient Education
Determining the Consistency Between Nurses and Artificial Intelligence (ChatGPT-5) in Delivering Scenario-Based Discharge Education to Coronary Artery Bypass Graft Patients: A Methodological Study
This methodological study aims to determine the level of agreement between nurses and an artificial intelligence system (ChatGPT-4.0) in providing scenario-based discharge education for patients who have undergone coronary artery…
- Trial name
- CABG-AI-EDU (NCT07263724)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Limb Edema, Surgical Site Infections
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients.
- Conditions
- Limb Edema, Surgical Site Infections, Leg Swelling, Compression Bandages
- Trial name
- PEACCE (NCT06603961)
- Testing
- CPG-EB group
- Where
- 2 sites in Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Coronary Artery Bypass Graft (CABG)
Saudi CABG Audit and Registry
The Saudi CABG Audit and Registry (SCAR) is a prospective, multicenter national clinical quality registry designed to systematically collect perioperative and long-term outcome data for all patients undergoing coronary artery…
- Trial name
- SCAR (NCT07316777)
- Testing
- Prospective Clinical Data Collection
- Volunteers
- 3,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Pain, Anxiety
Progressive Relaxation Exercises Before Mobilization:Effects on Pain, Anxiety and Physiologic Parameters CABG Patients
This study is planned as a randomized controlled experimental study to determine the effect of progressive relaxation exercises applied before mobilization on pain, anxiety and physiological parameters in patients undergoing…
- Conditions
- Pain, Anxiety, Physiological Parameter, Mobilization
- Trial name
- NCT06726239
- Testing
- Progressive relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Artery Bypass Graft (CABG)
Investigation of the Effects of Respiratory Muscle Training Combined With Otago Exercises in Elderly Patients Undergoing Coronary Artery Bypass Graft Surgery
A review of the literature suggests that high-intensity intermittent inspiratory muscle training (IMT) combined with the Otago exercise program may provide positive effects on early post-discharge recovery of patients aged 65…
- Trial name
- NCT07034846
- Testing
- High-intensity intermittent IMT and Otago Exercises Group
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul University - Cerrahpasa
CABG-patients, Saphenectomy
Clinical Impact of Surgical Wound Morbidity According to the Type of Saphenous Vein Harvesting Technique (Endoscopic vs. Open) in Patients Undergoing Myocardial Revascularization Surgery
The goal of this clinical trial is to compare two different techniques: endoscopic saphenous vein harvesting versus conventional open harvesting in patients undergoing coronary artery bypass grafting, either alone or in…
- Conditions
- CABG-patients, Saphenectomy, Endoscopic Surgery, Wound Complications
- Trial name
- EndOSiC (NCT07002658)
- Testing
- Harvesting of the saphenous vein graft
- Where
- Spain
- Volunteers
- 356 people
- Sponsor
- Hospital San Carlos, Madrid
Coronary Artery Bypass Graft CABG
Comparitive Effects of Elliptical Training vs Resistance Training on Cardiopulmonary Parameters in Post CABG Patients
COMPARATIVE EFFECTS OF ELLIPTICAL TRAINING VS RESISTANCE TRAINING ON CARDIOPULMONARY PARAMETERS IN POST CABG PATIENTS
- Trial name
- NCT06656117
- Testing
- Elliptical training, Resistance training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University