Clinical trials: Coronary Artery Bypass Graft
Coronary Artery Disease
Ticagrelor and Aspirin for the Prevention of Cardiovascular Events After Coronary Artery Bypass Surgery
Subjects will be consented to the study prior to Coronary Artery Bypass Graft (CABG) and randomly assigned to receive either ticagrelor 90 mg bid or placebo bid starting within 48 hours of surgery.
- Trial name
- TAP-CABG (NCT01373411)
- Testing
- ticagrelor
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Cardiology Research UBC
Pleural Effusions Post Coronary Artery Bypass Graft
Necessity of Using Pleural Drainage Tubes After IMA Harvesting During Cardiac Surgery
This prospective randomized controlled trial will examine the efficacy of reducing the number of chest tubes used in the postoperative cardiac surgery patient.
- Trial name
- NCT02147821
- Testing
- No Pleural Chest Tube
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- University of Calgary
Coronary Heart Disease
Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in CABG Surgery
Coronary heart disease (CHD) is the leading cause of death in the UK, accounting for 124,000 deaths (2006) and costing the UK economy over £7.9 billion a year.
- Trial name
- ERICCA (NCT01247545)
- Testing
- Remote ischaemic preconditioning, Control
- Where
- 28 sites in United Kingdom
- Volunteers
- 1,612 people
- Sponsor
- University College, London
Coronary Artery Bypass Graft
Effect of Deep Breathing Exercises on Post Operative Sleep Duration
This study will provide the evidence that during the postoperative period deep breathing exercise combined with physical training can positively influence the sleep duration and quality.
- Trial name
- NCT05058222
- Testing
- Deep Breathing Exercise after every 3hrs, each session consists of 10 deep breaths Exercise, Deep Breathing Exercise after every 3hrs, each session consist of 30 deep breaths Exercise
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Coronary Heart Disease
Efficacy and Safety of Hypertonic Sodium Lactate Solution Compared With 6% HES Solution in CABG Patients
The choice of fluid therapy is controversial in cardiac surgery. Numerous studies have shown that colloid is better as compared to crystalloids.
- Trial name
- NCT01654653
- Testing
- Hypertonic sodium lactate, 6% Hydroxy Ethyl Starch
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Postoperative Atrial Fibrillation
Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation
The purpose of this study is to compare the therapeutic strategies of rate control versus rhythm control in cardiac surgery patients who develop in-hospital postoperative atrial fibrillation or atrial flutter (AF).
- Trial name
- NCT02132767
- Testing
- Amiodarone, DC-cardioversion, Rate Control
- Where
- 23 sites in United States, Canada
- Volunteers
- 523 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain, Anxiety
Progressive Relaxation Exercises Before Mobilization:Effects on Pain, Anxiety and Physiologic Parameters CABG Patients
This study is planned as a randomized controlled experimental study to determine the effect of progressive relaxation exercises applied before mobilization on pain, anxiety and physiological parameters in patients undergoing…
- Conditions
- Pain, Anxiety, Physiological Parameter, Mobilization
- Trial name
- NCT06726239
- Testing
- Progressive relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Artery Disease, Perioperative Bleeding
Oral Versus Intravenous Tranexamic Acid in Off-Pump Coronary Artery Bypass Surgery
Tranexamic acid is commonly administered intravenously during cardiac surgery to reduce perioperative bleeding. Oral tranexamic acid may offer a simpler and less costly alternative, but its effectiveness in patients undergoing…
- Trial name
- TRANSCAB (NCT07740330)
- Testing
- Oral tranexamic acid, Exacyl®
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- Clinique Saint-Luc
Postoperative Pain, Coronary Artery Bypass Grafting
Serratus Anterior Plane and PECS II Blocks After Coronary Artery Bypass Grafting
This prospective randomized placebo-controlled trial was designed to evaluate the effects of ultrasound-guided bilateral pectoralis (PECS II) and serratus anterior plane (SAP) blocks on postoperative recovery in adult patients…
- Trial name
- NCT06793436
- Testing
- Bilateral Serratus Anterior Plane Block, Bilateral PECS II Block
- Where
- Turkey (Türkiye)
- Volunteers
- 243 people
- Sponsor
- Yuzuncu Yil University
Cardiovascular Diseases, Coronary Disease
Post Coronary Artery Bypass Graft (CABG) Study
To determine the relative effectiveness of moderate versus more aggressive lipid lowering, and of low dose anticoagulation versus placebo, in delaying saphenous vein coronary bypass graft atherosclerosis and preventing occlusion…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000463
- Testing
- lovastatin, cholestyramine, warfarin
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Percutaneous Coronary Intervention, Coronary Artery Bypass Graft Surgery, With or Without Valve Surgery
Cardiac Rehabilitation Peer Mentorship
The current study is a randomized controlled trial, being conducted at two hospitals in Toronto, Ontario, Canada, involving the randomization of cardiac inpatients into an intervention group, in which they will receive mentorship…
- Conditions
- Percutaneous Coronary Intervention, Coronary Artery Bypass Graft Surgery, With or Without Valve Surgery, Acute Coronary Syndrome, Chronic Stable Heart Failure
- Trial name
- NCT02204449
- Testing
- Cardiac Rehabilitation Peer Mentorship
- Where
- 2 sites in Canada
- Volunteers
- 94 people
- Sponsor
- University Health Network, Toronto
Post Induction Hypotension
Comparing the Hemodynamic Effects of Volume Loading vs Non-loading During Induction of Anesthesia in Fluid Responder Patients With Coronary Artery Disease Undergoing Elective Coronary Artery Bypass Graft Surgery: a Randomized Controlled Study.
All preoperative cardiac medications will be continued till the morning of the surgery, except angiotensin converting enzyme inhibitors.
- Trial name
- NCT05462847
- Testing
- Ringer acetate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Coronary Disease
Using Intraoperative Coronary Bypass Graft Imaging to Improve Graft Patency
The primary objective of the proposed study is to determine if a strategy of intraoperative patency assessment and graft revision can decrease the rate of graft occlusion or significant stenosis (>50%) at 6-12 weeks after…
- Trial name
- GRIIP (NCT00187421)
- Testing
- Indocyanine green intraoperative angiogram and transit-time flowmetry
- Where
- Canada
- Volunteers
- 156 people
- Sponsor
- Sunnybrook Health Sciences Centre
Coronary Artery Disease, Acute Cerebrovascular Accident
Incidence of Acute Cerebrovascular Events Using Either Minimized or Standard Cardiopulmonary Bypass Circuit
The prospective, randomized, two centre study investigates acute cerebrovascular events during extracorporal circulation and the early post operative outcome when using either the minimized cardiopulmonary bypass circuit…
- Conditions
- Coronary Artery Disease, Acute Cerebrovascular Accident, Intracranial Embolism, Embolism, Air
- Trial name
- ROCsafeTM (NCT00862160)
- Testing
- ROCsafeTM
- Where
- 2 sites in Germany
- Volunteers
- 64 people
- Sponsor
- Hannover Medical School
Heart Disease, Cardiovascular Disease
Best Bypass Surgery (BBS) Trial
There is evidence linking cardiopulmonary bypass to negative side effects when used for coronary artery bypass grafting. Coronary artery bypass grafting can be performed without the use of cardiopulmonary bypass.
- Trial name
- NCT00120991
- Testing
- Coronary artery bypass grafting
- Where
- Denmark
- Volunteers
- 341 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Angina Pectoris
Evaluation of Graft Material in Coronary Artery Bypass Grafting (CABG)
The aim of the study is to evaluate the patency in different kinds of vessels used as graft material in coronary artery bypass grafting.
- Trial name
- NCT01310725
- Testing
- Coronary artery bypass grafting
- Where
- Sweden
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Coronary Artery Disease
VEST Venous Graft External Support Pivotal Study
Prospective, multi-center, randomized, within-subject-controlled , trial, enrolling patients with multi vessel atherosclerotic coronary artery disease, scheduled to undergo SVG CABG with arterial grafting of IMA to LAD and two or…
- Trial name
- VEST Pivotal (NCT03209609)
- Testing
- VEST, Coronary artery bypass vein grafts
- Where
- 17 sites in United States, Canada
- Volunteers
- 224 people
- Sponsor
- Vascular Graft Solutions Ltd.
Arrhythmias, Cardiac
Prevention of Dysrhythmias on the Cardiac Intensive Care Unit - Does Maintenance of High-normal Serum Potassium Levels Matter
The purpose of this study is to determine whether a strategy of maintaining serum potassium levels at ≥3.6 mEq/L is non-inferior to a strategy of usual treatment (≥4.5 mEq/L) on the occurrence of new onset atrial fibrillation…
- Trial name
- TIGHT-K (NCT04053816)
- Testing
- Potassium
- Where
- United Kingdom
- Volunteers
- 1,684 people
- Sponsor
- Barts & The London NHS Trust
Frail Elderly Syndrome, Coronary Heart Disease
Frailty Syndrome in Daily Practice of Interventional Cardiology Ward
The impact of frailty on immediate and long term outcomes of invasive treatment of coronary artery disease is not fully characterized.
- Conditions
- Frail Elderly Syndrome, Coronary Heart Disease, Acute Coronary Syndrome, Coronary Artery Bypass Grafting
- Trial name
- FRAPICA (NCT03209414)
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Silesia
Postoperative Hemorrhage
Hetastarch and Bleeding Complications After Off-Pump Coronary Bypass Surgery
There has been continuing debate about whether use of hetastarch for volume replacement in coronary artery bypass surgery [CABG] increases the risk of postoperative bleeding.
- Trial name
- NCT00307138
- Testing
- hetastarch
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Kaiser Permanente
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