Clinical trials: Coronary Artery Aneurysm
Cardiac Pacing, Artificial, Aneurysm, Brain
Rapid Ventricular Pacing During Cerebral Aneurysm Surgery: a Study Concerning the Safety for Heart and Brain
Rapid ventricular pacing (RVP) is a technique to obtain flow arrest for short periods of time during dissection or rupture of the aneurysm. RVP results in an adequate fall in blood pressure which presents as an on-off phenomenon.
- Conditions
- Cardiac Pacing, Artificial, Aneurysm, Brain, Arteriovenous Malformations, Cerebral
- Trial name
- NCT03184233
- Testing
- Rapid ventricular pacing, No rapid ventricular pacing
- Where
- Belgium
- Volunteers
- 59 people
- Sponsor
- University Hospital, Antwerp
Coronary Artery Disease
Vascular Function on the First Day After Cardiac Surgery
This study examines the flow mediated dilation (FMD) of the brachial artery before and after cardiac surgery. FMD is measured with ultrasound technique.
- Trial name
- NCT02001090
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- Norwegian University of Science and Technology
Aortic Aneurysm, Iliac Aneurysm
Comparison of Aorto-iliac Endovascular Interventions With and Without the EndoNaut Workstation
The aim of this retrospective, multicenter study is to demonstrate that the use of EndoNaut for aortoiliac endovascular procedures has a clinical impact for the patient (reduction in irradiation and the volume of contrast…
- Conditions
- Aortic Aneurysm, Iliac Aneurysm, Stenoses, Aortic, Iliac Artery Stenosis
- Trial name
- COM-ENDO (NCT04714268)
- Testing
- Aorto-iliac endovascular procedure
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Therenva
Coronary Artery Ectasia
A New Classification and Interventional Therapy for Coronary Artery Ectasia
This study is aim to present a new classification for coronary artery ectasia and find the best interventional therapy for different types of patients were treated and studied.
- Trial name
- NCIPCAE (NCT04265989)
- Testing
- Single BMS, Single or Double BMS, BMS+DES
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Ectasia
Endothelial NO Synthase Polymorphic Gene in Coronary Artery Dilation Disease
Introduction: The coronary artery dilatations disease (Coronary artery aneurysm/coronary artery ectasia) characterized by inappropriate coronary artery dilations.
- Trial name
- NCT06220682
- Testing
- The specific genetic PCR laboratory test were performed for all selected patients for eNOS SNPs
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Coronary Artery Disease, Arterial Stiffness, Blood Pressure
Expanded Studies on the SCAPIS Stockholm Reexamination Cohort
The Swedish CArdioPulmonary bioImage Study (SCAPIS) is a unique, large-scale national research initiative involving 30,000 randomly selected individuals aged 50-64, recruited between 2014 and 2018.
- Conditions
- Coronary Artery Disease, Arterial Stiffness, Blood Pressure, AORTIC VALVE DISEASES, Mitral Valve Stenosis and/or Insufficiency
- Trial name
- SCAPIS-ReEx (NCT07476703)
- Testing
- Coronary computer tomography (CCTA), Echocardiograhy and aortic ultrasound, Liver elastography
- Where
- Sweden
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Danderyd Hospital
Coronary Artery Disease, Postoperative Complications
Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery
This study evaluates the efficacy and safety of single dose preoperative ferric carboxymaltose in the prevention of postoperative infections and blood transfusions in patients scheduled for cardiac surgery.
- Conditions
- Coronary Artery Disease, Postoperative Complications, Aortic Valve Stenosis, Mitral Valve Disease
- Trial name
- PREFER-CABG (NCT03574311)
- Testing
- Ferric carboxymaltose, Physiological saline
- Where
- Finland
- Volunteers
- 210 people
- Sponsor
- Turku University Hospital
Coronary Angiography, Coronary Artery Disease
Assessment Of Total Coronary Circulation Time Using TIMI Frame Count Method (TCCT-TIMI)
The aim of this study is to evaluate and describe the total coronary circulation time (TCCT) by using TIMI frame count method in patients performed coronary angiography.
- Conditions
- Coronary Angiography, Coronary Artery Disease, Coronary Artery Ectasia, Slow-Flow Phenomenon
- Trial name
- TCCT-TIMI (NCT02818127)
- Testing
- coronary angiography
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Vascular and Molecular Cardiology Society
Coronary Artery Bypass Grafting, Heart Valve Disease
LLM-Based Intelligent Health Management Assistant in Life-Cycle Health Management of Cardiac Surgery Patients
This is a single-center, prospective, randomized, open-label, parallel-controlled clinical study to evaluate the effectiveness of a large language model (LLM)-based intelligent health management assistant in the life-cycle health…
- Conditions
- Coronary Artery Bypass Grafting, Heart Valve Disease, Aortic Aneurysm, Aortic Dissection
- Trial name
- cFT-LLM (NCT07521488)
- Testing
- LLM-Based Intelligent Health Management Assistant
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Anzhen Hospital
Kawasaki Disease
Study of Efficacy and Safety of Canakinumab in Pediatric Patients With Kawasaki Disease
The purpose of this trial is to evaluate whether, in Intravenous Immunoglobulin-naïve or refractory patients diagnosed with active Kawasaki disease, administration of canakinumab controls fever and acute phase reactants.
- Trial name
- NCT02980263
- Testing
- Canakinumab
- Sponsor
- Novartis Pharmaceuticals
Aortic Diseases, Cardiac Surgical Procedures
Selective Antegrade Cerebral Perfusion and Perioperative Optic Nerve Sheath Diameter in Ascending Aortic Surgery
In ascending aortic surgery the distal anastomosis may be constructed with the aortic cross-clamp maintained, or, where the extent of the aortic pathology and the geometry of the graft require it, after release of the cross-clamp…
- Conditions
- Aortic Diseases, Cardiac Surgical Procedures, Aortic Aneurysm, Thoracic, Delirium - Postoperative
- Trial name
- SACP-ONSD (NCT07800806)
- Testing
- Optic nerve sheath and optic nerve diameter ultrasonography, Transcranial Doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Coronary Artery Disease, Aortic Aneurysm
Computed Tomography Dose Reduction Using Sequential or Fast Pitch Sprial Technique
This is a prospective, controlled observational trial of patients undergoing clinically indicated cardiothoracic computed tomography (CT), including pulmonary or aortic angiography and coronary CT angiography (CCTA).
- Conditions
- Coronary Artery Disease, Aortic Aneurysm, Pulmonary Embolism
- Trial name
- CTDOSE (NCT01272453)
- Where
- 9 sites in United States, Saudi Arabia
- Volunteers
- 2,640 people
- Sponsor
- Gilbert L. Raff, MD
Thoracic Aortic Aneurysm
HEART: Pilot Randomized Controlled Trial
The purpose of this study is to determine whether spironolactone reduces aortic stiffness, measured by carotid-femoral pulse wave velocity (cfPWV), compared with placebo, in patients with degenerative thoracic aortic aneurysms.
- Trial name
- NCT07483177
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Coronary Artery Ectasia
Coronary Artery Ectasia, Efficacy of Various Anti Thrombotic Regimens.
1. To evaluate short and intermediate clinical outcome of different anti-thrombotic regimens on major adverse cardiac events (MACE) and quality of life in coronary artery ectasia patients. 2.
- Trial name
- NCT05718531
- Testing
- Rivaroxaban 2.5 Mg Oral Tablet twice daily, Clopidogrel 75 Mg Oral Tablet, Aspirin tablet 75 mg
- Volunteers
- 200 people
- Sponsor
- Assiut University
Cardiac Rhythm Disorders, Urological Disorders
Product Surveillance Registry
The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products.
- Conditions
- Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders
- Trial name
- PSR (NCT01524276)
- Where
- 402 sites in United States, Argentina and 39 more
- Volunteers
- 100,000 people
- Sponsor
- Medtronic
Acute Coronary Syndrome, Coronary Artery Ectasia
Antithrombotic Therapy in Acute Coronary Syndromes and Coronary Artery Ectasia
The optimal anti-thrombotic therapy to prevent recurrent ischemic events in patients with acute coronary syndrome and coronary artery ectasia (CAE) remains unclear.
- Trial name
- OVER-TIME (NCT05233124)
- Testing
- Rivaroxaban 15 MG, Acetylsalicylic acid 100mg, Clopidogrel 75 Mg Oral Tablet
- Where
- 2 sites in Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Atherosclerosis of Coronary Artery, Cardiovascular Disease
Radiation Dose From Computed Tomography Before and After Implementation of a High Pitch Dual Spiral Technique
The purpose of this study is to compare the radiation exposure of a variety of chest CT examinations performed on the current state of the art CT scanners (64 slice, dual source CT scanner) with the radiation exposure for…
- Conditions
- Atherosclerosis of Coronary Artery, Cardiovascular Disease, Pulmonary Embolism, Aortic Aneurysm Without Mention of Rupture Nos
- Trial name
- FLASH (NCT01111760)
- Where
- United States
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Michael Gallagher
Kawasaki Disease, Pilot Study
Model-informed Dose Optimization for Rivaroxaban in Children With Giant Coronary Artery Aneurysm After Kawasaki Disease
Based on a population pharmacokinetic model-based dose optimization study, a 15 mg-equivalent, age-, and bodyweight-adjusted dosing regimen for Chinese children with giant coronary artery aneurysms after Kawasaki disease was…
- Conditions
- Kawasaki Disease, Pilot Study, Coronary Artery Aneurysm, Rivaroxaban
- Trial name
- NCT06978439
- Testing
- Rivaroxaban (Xarelto)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Fudan University
Coronary Artery Ectasia
Safety And Efficacy Results of Percutaneous Renal Stent Implantation in Ectatic and Aneurysmatic Coronary Arteries
The aim of this study was to evaluate the efficacy and safety of renal stents implanted in ectatic/aneurysmatic coronary arteries.
- Trial name
- NCT05410678
- Testing
- Renal stent
- Volunteers
- 63 people
- Sponsor
- Bursa Postgraduate Hospital
Iliac Aneurysm, Angiography
Iliac Branch Device Movement During Cardiac Cycle (IBD-dynamics)
The incidence of isolated common iliac artery (CIA) aneurysms is low, but in combination with an abdominal aortic aneurysm (AAA) they are found in approximately 20-40% of cases.
- Conditions
- Iliac Aneurysm, Angiography, AAA
- Trial name
- NCT03762525
- Testing
- ECG gated CTA
- Where
- 3 sites in Netherlands
- Volunteers
- 45 people
- Sponsor
- Rijnstate Hospital