Clinical trials: Contusions
Patients With Respiratory Failure and Shocked
Effect of Arterio-venous ECMO on Severe Sepsis and ARDS
To evaluate and compare the effect of immunoadsorption effect of A-V ECMO on course of sepsis weaning from inotropes, weaning from the ventilator, duration of ICU stays and effect on mortality rate in patients with septic shock…
- Trial name
- NCT04555798
- Testing
- Meropenem Injection, A-V ECMO
- Where
- Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- Mohamed Gaber Allam
Traumatic Lung Injury
Impact of the Early Use of High Flow Nasal Cannula in Patients With Post-traumatic Lung Contusion, a Randomized Clinical Trial
We hypothesize that early and continuous administration of oxygen via high flow nasal cannula in patients with lung contusion and non-severe acute lung injury might reduce the incidence of intubation and hold the deterioration of…
- Trial name
- NCT05509088
- Testing
- high flow nasal cannula
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
TSA, Bruise
Natural History of Pain After Shoulder Arthroplasty Conducted With Multimodal Analgesia
This study aims to identify the timeline of pain following total shoulder replacement with the goal of developing data for a subsequent randomized trial.
- Conditions
- TSA, Bruise, Pain, Postoperative
- Trial name
- TSA (NCT03021096)
- Testing
- Surveys
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Traumatic Brain Injury
Rehabilitation Research and Training Center for Traumatic Brain Injury Interventions--Teen Online Problem Solving Study
This study will evaluate the effectiveness of an Internet-based psychosocial treatment in improving problem-solving, communication skills, stress management strategies, and coping among teens who have had a traumatic brain injury…
- Trial name
- RRTC--TOPS (NCT01042899)
- Testing
- Teen Online Problem Solving (TOPS), Teen Online Problem Solving--Teen Only (TOPS-TO), Internet Resources Comparison (IRC)
- Where
- 5 sites in United States
- Volunteers
- 153 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Edematous Fibrosclerotic Panniculopathy (EFP), Cellulite
Effects of Mitigation Treatments on Bruising of CCH-aaes Treatment of Buttock Cellulite
This study will investigate treatments that may mitigate bruising after QWO™ (Collagenase clostridium histolyticum [CCH]-aaes) treatment of cellulite in the buttocks.
- Trial name
- MOBI (NCT04677712)
- Testing
- CCH-aaes, Compression, Cold Packs
- Where
- 8 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Pulmonary Contusion
Pulmonary Contusion Flail Chest Complex
The study included 20 adult patients presented by multiple fractured ribs (flail segment) with thoracic trauma severity score (TTSS) between 5 and 15.
- Trial name
- NCT03090308
- Testing
- Noninvasive positive pressure ventilation
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Muscular Atrophy, Sprains
Study to Assess the Efficacy and Safety of Ibuprofen 50 mg/g Gel Compared to Profenid 25mg/g Gel
The aim of this study is to determine that ibuprofen 50mg/g gel is effective and safety treating patients with muscle aches, joint pains or due to sprains, bruises, tendinitis or myofascial compared to Profenid 25mg/g gel.
- Conditions
- Muscular Atrophy, Sprains, Tendonitis
- Trial name
- NCT01373697
- Testing
- Ibuprofen, Profenid
- Where
- Brazil
- Volunteers
- 144 people
- Sponsor
- Laboratório Teuto Brasileiro S/A
Spinal Cord Injury, Acute
Cord Blood Cells in Patients With Acute SCI
This is a prospective, single-blinded, single-center, randomized, comparative, interventional clinical study of systemic mononuclear multiple allogenic cord blood cells administration safety and efficiency in patients having…
- Trial name
- SUBSCI II (NCT05693181)
- Testing
- Multiple systemic (i.v.) administration of allogenic non-related group- and rhesus-compatible mononuclear cord blood cells, Control vehicle (sterile saline)
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Contusions
Phase III Trial to Assess the Safety and Efficacy of TK-254RX in Patients With Contusions
This study is an open-label, multi-centric clinical trial to evaluate the safety and efficacy of TK-254RX in patients with contusions. The primary objective of this study is to assess the safety of TK-254RX.
- Trial name
- NCT06871046
- Testing
- Esflurbiprofen Topical System (EFTS)
- Where
- 5 sites in Germany
- Volunteers
- 221 people
- Sponsor
- Teikoku Seiyaku Co., Ltd.
Liposuction, Bruising
Bridging the Healing Gap: A Single-Blind Clinical Trial Assessing the Efficacy of Carboxy-gel in Reducing Bruising and Pain Post-Liposuction
The goal of this clinical trial is to evaluate if CO2 Lift reduces bruising and pain after Liposuction. The study also aims to explore changes in patient satisfaction.
- Conditions
- Liposuction, Bruising, Inflammation, Pain, Postoperative
- Trial name
- CO2L001 (NCT06791577)
- Testing
- Carboxytherapy
- Where
- 3 sites in Brazil, Colombia and 1 more
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Contusions, Sprains
To Evaluate the Efficacy and Safety Aliviador Compared to Gelol in Patients With Contusions, Sprains, Trauma and Muscle Injury.
Multicenter, randomized, double-blind trial, to evaluate the efficacy and safety Aliviador compared to Gelol in the relief of signs and symptoms in patients with contusions, sprains, trauma and muscle injury start with less than…
- Conditions
- Contusions, Sprains, Trauma, Muscle Injury
- Trial name
- LBB-ALI-01/09 (NCT01097798)
- Testing
- Aliviador, Gelol
- Where
- 3 sites in Brazil
- Volunteers
- 120 people
- Sponsor
- Laboratorio Brasileiro de Biologia
Dermatochalasis of Upper Eyelid
Does Unilateral Compression Dressing Reduce Postoperative Swelling and Bruising After Upper Eyelid Blepharoplasty?
This study evaluated whether applying a compression dressing to one eyelid after upper eyelid blepharoplasty (eyelid lift surgery) reduces swelling, bruising, and discomfort compared to the untreated eyelid.
- Trial name
- COMPRESS-BLEPH (NCT07701265)
- Testing
- Compression Dressing (CD), No Dressing (Standard Postoperative Care)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Fatma Poslu Karademir
Bruise, Contusion
Development of Validated Bruise Scale in HNV
Subjects will have a mechanically induced bruise photographed over a period of 11 days to record the healing process. Assessors will rate the bruises to develop a bruising scale.
- Trial name
- NCT04526275
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Cearna, Inc.
Acute Pain
Diclofenac Patch for the Treatment of Acute Pain Due to Mild to Moderate Wrist Sprain, Strain or Contusion
The purpose of the study is to assess the effectiveness of once daily application of a diclofenac sodium topical patch in reducing acute pain due to mild to moderate wrist sprain, strain or contusion when applied to the painful…
- Trial name
- WIND (NCT00869063)
- Testing
- Diclofenac Sodium Patch
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- Cerimon Pharmaceuticals
Contusions, Incision
Dermal Wound Closure Using Silkam®
Assessment of performance of Silkam® suture material for skin closure. A prospective, single center, single arm, observational study in daily practice.
- Conditions
- Contusions, Incision, Laceration
- Trial name
- DERMASILK (NCT05225714)
- Where
- Spain
- Volunteers
- 161 people
- Sponsor
- Aesculap AG
Traumatic Brain Injury
Trauma Molecular Processes
The TRAUMAP study will function as a brain tissue repository for biopsy specimens from patients with traumatic brain injury undergoing brain surgery for contusion removal.
- Trial name
- TRAUMAP (NCT07683169)
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Ecchymosis After Periorbital Rejuvenation With Botulinum Toxin Type A, Crow's Feet Lines
A Real-World Study on Effect of Hirudoid on Ecchymosis After Treatment of Crow's Feet With Botulinum Toxin Type A
Botulinum toxin type A (commonly referred to as 'Botox') injections are a treatment that dermatologists regularly use to smoothen wrinkles such as 'Crow's feet', to rejuvenate the skin surrounding the eye (the 'periorbital…
- Conditions
- Ecchymosis After Periorbital Rejuvenation With Botulinum Toxin Type A, Crow's Feet Lines, Lateral Canthal Lines, LCL
- Trial name
- NCT07388927
- Testing
- Hirudoid (heparinoids) ointment, 3mg/g
- Volunteers
- 48 people
- Sponsor
- DKSH Management (Thailand) Limited
Edematous Fibrosclerotic Panniculopathy, Cellulite
Study of Different Interventions to Reduce Bruising Following CCH-Aaes Treatment for Cellulite of the Buttocks
The study will evaluate the effect of different doses, strengths (concentrations), diluent additives, depths of injection, and methods of injection on the severity of bruising potentially induced by QWO (collagenase clostridium…
- Trial name
- APHRODITE (NCT05419505)
- Testing
- CCH-aaes, Antifibrinolytic Agent
- Where
- 13 sites in United States
- Volunteers
- 91 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Lung Trauma, Lung Contusion
Effects of Non-invasive Ventilation Therapies on the Lung in Hypoxemic Chest Trauma Patients
Chest trauma is common in traumatology. Its management is based on ventilatory therapies, among which non-invasive ventilation (NIV) is commonly used.
- Trial name
- VentiChest (NCT06735872)
- Testing
- Non invasive ventilation (NIV), High flow oxygen therapy (HFO)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Blunt Chest Trauma, Respiratory Failure
Combined Lung and Diaphragmatic Ultrasound to Predict Respiratory Failure in Blunt Chest Trauma
Blunt chest trauma is a leading cause of emergency hospital visits and can result in severe breathing complications such as hypoxemic respiratory failure.
- Conditions
- Blunt Chest Trauma, Respiratory Failure, Thoracic Injuries, Hypoxemic Respiratory Failure
- Trial name
- NCT07807566
- Volunteers
- 130 people
- Sponsor
- Assiut University