Clinical trials: Controlled Asthma
Asthma
Study of Inhaled Glucocorticosteroid Administration in Asthma Patients
Once-daily inhaled glucocorticosteroids treatment can sufficiently control airway inflammation in asthma patients.
- Trial name
- NCT00559689
- Testing
- Budesonide,hydrofluoroalkane-beclomethasone dipropionate, Budesonide,hydrofluoroalkane-beclomethasone
- Where
- Japan
- Volunteers
- 24 people
- Sponsor
- Hamamatsu University
Asthma
Mobile Phone Text for Optimizing Asthma Treatment
The study aims at providing information on how the Short Message Service (SMS) tool influences self-management in asthma patients and to assess the resulting health related effect.
- Trial name
- NCT00917410
- Testing
- SMS support
- Where
- Denmark
- Volunteers
- 244 people
- Sponsor
- University of Copenhagen
Asthma
Clinical Study to Explore the Efficacy of ACT-129968 in Patients With Partly Controlled Asthma
This study will assess the efficacy and safety of ACT-129968 in subjects with partly controlled asthma on reliever therapy only.
- Trial name
- CONTROL (NCT01225315)
- Testing
- Setipiprant
- Where
- 97 sites in United States, Australia and 11 more
- Volunteers
- 438 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Asthmatic Patients
FACTO Study (Foster® As Complete Treatment Option)
Double blind, multinational, multicentre, randomised, 2 arm parallel group study
- Trial name
- FACTO (NCT00901368)
- Testing
- FOSTER, Seretide
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 431 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Asthma, Healthy Volunteers
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of RV6153
RV6153 is a new medicine being developed for possible treatment of asthma and smoking related lung disease (also known as chronic obstructive pulmonary disease - COPD).
- Trial name
- NCT02517359
- Testing
- RV6153 single dose, RV6153 14 day repeat dose, RV6153 28 day repeat dose
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Respivert Ltd
Respiratory Tract Diseases, Pulmonary Disease, Chronic Obstructive
Feedback Reports and e-Learning in Primary Care Spirometry
Spirometry is a biomedical test to measure lung function in subject who (may) have a chronic respiratory condition. Performing the test requires a certain level of training and experience from the health care professional who…
- Conditions
- Respiratory Tract Diseases, Pulmonary Disease, Chronic Obstructive, Asthma
- Trial name
- FRESCO (NCT00962455)
- Testing
- e-learning & performance feedback, usual practice
- Where
- Netherlands
- Volunteers
- 1,135 people
- Sponsor
- Radboud University Medical Center
Asthma, Healthy
Inflammatory Markers in Exhaled Breath (Condensate) in Childhood Asthma
Background: Exhaled nitric oxide and inflammatory biomarkers in exhaled breath condensate may be useful to diagnose and monitor childhood asthma.
- Conditions
- Asthma, Healthy, Children
- Trial name
- NCT00404976
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Asthma
Self-Management Of Asthma By Forced Oscillation Technique
Self-management strategies for asthma, including patients engagement and adherence to personalised action plans with advice on recognizing and responding to deterioration in control with effective treatments can improve asthma…
- Trial name
- PIANOFORTE (NCT04963140)
- Testing
- Optimized self-management of asthma, Conventional self-management of asthma
- Where
- 9 sites in Australia, France and 1 more
- Volunteers
- 39 people
- Sponsor
- Restech Srl
Allergic Asthma
Study to Evaluate the Safety and Efficacy TPI ASM8 in Subjects With Asthma
The researchers propose to study the airways of asthmatics given TPI ASM8 for 14 days, and examine the protective effects on allergen-induced bronchoconstriction, hyperresponsiveness and airway inflammation.
- Trial name
- NCT00550797
- Testing
- TPI ASM8
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Syntara
Asthma
Randomized, Placebo-controlled, Multi-dose, Study Comparing Budesonide/Formoterol to Symbicort® in Asthmatic Patients
A randomized multiple-dose, placebo-controlled, parallel group design consisting of a 2-week run-in period followed by a 6-week treatment period of the placebo, Test product (Budesonide 80 mcg / Formoterol fumarate dihydrate 4.5…
- Trial name
- NCT03015259
- Testing
- Budesonide/Formoterol fumarate dihydrate, Symbicort
- Where
- 95 sites in United States
- Volunteers
- 1,762 people
- Sponsor
- Kindeva Drug Delivery
Asthma
Investigation of the 24 Hour Forced Expiratory Flow in 1 Second (FEV1) Profile of a Single Dose of Indacaterol/Mometasone Delivered Via the TWISTHALER® Device in Adult Patients With Persistent Asthma
This study is designed to provide data about the 24 hours FEV1 profile, safety and tolerability of indacaterol/mometasone TWISTHALER device compared to placebo and using fluticasone/salmeterol as an active control.
- Trial name
- NCT00557440
- Testing
- fluticasone propionate/salmeterol, indacaterol maleate / mometasone furoate
- Where
- 6 sites in Belgium, Germany
- Volunteers
- 37 people
- Sponsor
- Novartis
Asthma (Diagnosis), OSA - Obstructive Sleep Apnea
Obstructive Sleep Apnoea and Difficult Asthma (OSADA)
The OSADA (Obstructive Sleep Apnoea in Difficult Asthma) trial is an open-label, randomized control trial investigating the impact of diagnosing and treating obstructive sleep apnoea (OSA) on a asthma control in patients with…
- Conditions
- Asthma (Diagnosis), OSA - Obstructive Sleep Apnea, CPAP Treatment
- Trial name
- OSADA (NCT07160868)
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Ireland
- Volunteers
- 80 people
- Sponsor
- St. James's Hospital, Ireland
Rhinitis or Rhinoconjunctivitis With or Without Asthma Induced by Hypersensitivity to Olea Europea Pollen
Subcutaneous Immunotherapy Treatment for Patients With Hypersensitivity to Olea Europaea Pollen
The objective of this trial is to assess the clinical efficacy of a modified allergen extract of Olea europaea pollen in the treatment of patients affected by allergic rhinitis/rhinoconjunctivitis (with or without episodic…
- Trial name
- OLEA (NCT00831025)
- Testing
- Immunotherapy with modified extract of Olea europaea pollen
- Where
- 7 sites in Spain
- Volunteers
- 158 people
- Sponsor
- Laboratorios Leti, S.L.
Severe Allergic Asthma
Nocturnal TLA for Severe Allergic Asthma After Withdrawal of Omalizumab Therapy
This is a randomized, controlled study with a 48-week treatment phase to determine the clinical efficacy of temperature controlled laminar flow device (TLA, Airsonett™) in the patients with severe allergic asthma who are…
- Trial name
- NCT03480815
- Testing
- Nocturnal Temperature Controlled Laminar Flow Device, None Device
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Nasal Polyps
Study of Efficacy of Fevipiprant in Patients With Nasal Polyposis and Asthma
A Phase 3b Proof-of-Concept study to evaluate the ability of fevipiprant 150 mg and 450 mg, compared with placebo, as add-on to nasal spray standard-of-care (SoC), in reducing endoscopic nasal polyp score in adult (≥ 18 years)…
- Trial name
- THUNDER (NCT03681093)
- Testing
- Fevipiprant 150 mg, Fevipiprant 450 mg
- Where
- 25 sites in United States, Argentina and 7 more
- Volunteers
- 98 people
- Sponsor
- Novartis Pharmaceuticals
Lung Diseases, Asthma
Environmental Tobacco Smoke Exposure Reduction in High-Risk Preteens
This study will determine the effect of combining counseling, urine cotinine feedback, and incentives in reducing environmental tobacco smoke (ETS) exposure and susceptibility to smoking among high-risk preteens.
- Trial name
- NCT00217893
- Testing
- Counseling, Urine Cotinine Feedback, Contingent Incentives
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- San Diego State University
Atherosclerosis
A Study To Determine The Effect Of SB-480848 On Asthma
The purpose of this study is to compare the effects of SB-480848 with placebo in subjects with asthma.
- Trial name
- NCT00368576
- Testing
- SB 480848, tablets
- Where
- 7 sites in United States, Germany
- Volunteers
- 67 people
- Sponsor
- GlaxoSmithKline
Asthma
Randomised Placebo Controlled Study of Effects of Therapeutic Hookworm Infection in Asthma
There has been considerable debate over the last 30 years about the interaction between asthma and parasitic infection. It has been suggested that at least part of the reason for the increasing prevalence of asthma in the…
- Trial name
- NCT00469989
- Testing
- Infection with hookworm larvae
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Nottingham
Allergy
A Phase III Study to Assess Efficacy and Safety of STALORAL® 300 IR Sublingual Immunotherapy (SLIT) in Asthmatic Patients Allergic to House-dust Mites
A phase III study to assess the efficacy and safety of sublingual immunotherapy with STALORAL dust mites solution compared with placebo for reduction of asthma symptoms.
- Trial name
- NCT00660452
- Testing
- Staloral
- Where
- China
- Volunteers
- 484 people
- Sponsor
- Stallergenes Greer
Asthma in Children, Medication Adherence
Financial Incentives to Improve Asthma
The aim of this pilot randomised controlled trial is to assess the effectiveness of a short-term financial incentives intervention at bringing about behaviour change, namely short-medium term improvements in inhaled…
- Trial name
- FINA (NCT05322044)
- Testing
- Financial incentives
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Imperial College London