Clinical trials: Contracture
Contracture of Elbow Joint
Self Digital Photography for Assessing Elbow Range of Motion
Loss of elbow range of motion can significantly affect activities of daily living. Measuring elbow range of motion is critical for tracking post surgical outcomes.
- Trial name
- NCT02985788
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS)
Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test
The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon problems, or nerve compression).
- Conditions
- Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis
- Trial name
- NCT07158892
- Testing
- Diagnostic Advance Care Planning Discussion, Informational Statement Only
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Texas at Austin
Stretch, Plantar Fascia; Contracture
Effect of Stretching Exercises on Plantar Fascia
The plantar fascia (PF) extends over the calcaneal bone with a thin band corresponding to the calcaneal periosteum, continuing as the paratenon of the Achilles tendon.The triceps surae complex, serving as the main extensor and…
- Conditions
- Stretch, Plantar Fascia; Contracture, Fasciitis, Plantar
- Trial name
- NCT06370741
- Testing
- Stretching with/without device
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Okan University
Capsular Contracture, Implant, Pediatric Cataract
Capsular Outcomes of Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
Lens capsular often changes after pediatric cataract surgery，causing complications such as anterior capsulerhexis shrinkage, visual axis opacification (VAO), zonular dehiscence and so on.
- Trial name
- capsular (NCT04803097)
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Yune Zhao
Osteo Arthritis Knee
Utilization of a Knee Brace With Extension Swing
The purpose of this research is to help determine if use of the Guardian brace during prehab and post-op rehab after TKA can help improve functional outcomes and reduce the incidence of post-operative flexion contractures which…
- Trial name
- NCT05179044
- Testing
- Guardian Sport Rehabilitator knee brace
- Where
- United States
- Sponsor
- NYU Langone Health
Breast Cancer
Breast Capsular Contracture Following Post-Mastectomy Reconstruction in Women Treated With the Leukotriene Inhibitor Zafirlukast: A Phase II Trial
A 2 arm, 90 patient (45 per cohort) trial in patients with breast cancer who will be undergoing mastectomy with immediate tissue-expander reconstruction to determine whether treatment with zafirlukast (20mg PO BID) can reduce or…
- Trial name
- NCT02950480
- Testing
- zafirlukast, Standard of Care (no intervention)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Francisco
Carcinoma, Non-Small-Cell Lung
A Study of MM-121 Combination Therapy in Patients With Advanced Non-Small Cell Lung Cancer
A Phase 1-2 study of MM-121 in combination with standard therapy for non-small cell lung cancer (NSCLC).
- Trial name
- NCT00994123
- Testing
- MM-121, Erlotinib
- Where
- 38 sites in United States, Canada and 4 more
- Volunteers
- 162 people
- Sponsor
- Merrimack Pharmaceuticals
Burn's Associated Contracture
Injectable Collagenase For Burns' Associated Contracture
A pilot experiment to test the efficiency of the enzyme Collagenase in treating contractures which result's from burn's healing process.
- Trial name
- NCT01237964
- Testing
- Xiaflex (FDA approved collagenase)
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Sheba Medical Center
Ankle Equinus, Ankle Contracture
Ankle Equinus Contracture Treated With Dynamic Splinting
The purpose of this study is to determine if the Ankle Dorsiflexion Dynasplint System (DS) is effective in treating contracture for patients with Ankle Equinus secondary to diabetes mellitus.
- Conditions
- Ankle Equinus, Ankle Contracture, Diabetes Mellitus
- Trial name
- NCT01238484
- Testing
- Standard of care, Dynasplint
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Dynasplint Systems, Inc.
Ankle Osteoarthritis, Knee Osteoarthritis
Gait Asymmetry Assessed Using Portable Gait Analysis System
To date, detailed analysis of movement patterns in orthopaedic conditions are mainly performed in research projects. Because these tests are time consuming, they are not feasible in clinical routine or in standard examinations.
- Conditions
- Ankle Osteoarthritis, Knee Osteoarthritis, Hip Osteoarthritis, Lumbar Spine Stenosis
- Trial name
- Asymmetry (NCT02489188)
- Testing
- arthroplasty, manual therapy, lumbar spinal stenosis decompression
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Brain Injuries, Disorder of Consciousness
Long Term Effects of Soft Splints on Stroke Patients and Patients With Disorders of Consciousness
The purpose of this study is to assess the effects on upper limb spasticity of soft splints worn during three weeks three hours a day by patients with stroke or disorders of consciousness.
- Conditions
- Brain Injuries, Disorder of Consciousness, Stroke, Spasticity as Sequela of Stroke
- Trial name
- NCT03008486
- Testing
- Real soft splint (6 cm)
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Géraldine Martens
Joint Contracture, Mechanical Ventilation
Using Continuous Passive Motion to Prevent Ankle Problems in ICU Patients
The goal of this clinical trial is to learn if continuous passive motion (CPM) helps prevent ankle joint contracture and muscle loss in critically ill, mechanically ventilated ICU patients.
- Conditions
- Joint Contracture, Mechanical Ventilation, ICU-acquired Weakness, Critical Illness
- Trial name
- NCT06944431
- Testing
- Continuous Passive Motion (CPM)
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Dupuytren Contracture
Dupuytren´s Disease Study. Primary Disease, MCP Joint, Xiapex, PNF
Aim: Clinical RCT comparing functional results and recurrence rate following enzymatic treatment vs. needle aponeurotomy. Materials and methods: 30° or more contracture of only one metacarpophalangeal (MCP) joint contracture of…
- Trial name
- NCT02647619
- Testing
- Xiapex, Needle aponeurotomy
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Burn, Burn Contracture of Skin
Development and Clinical Study of Burn Wound Nursing Dressing Based on Sodium Hyaluronate Carbomer Composite Hydrogel
Development and clinical study of burn wound nursing dressing based on sodium hyaluronate carbomer composite hydrogel
- Conditions
- Burn, Burn Contracture of Skin, Burn Degree Second
- Trial name
- NCT07568600
- Testing
- sodium hyaluronate carbomer composite hydrogel
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Shoulder Impingement, Shoulder Pain
Pragmatic Posterior Capsular Stretch
Various stretches are used to lengthen the posterior shoulder capsule. No study has reported the comparison of the pragmatic posterior capsular stretch and cross body stertch
- Conditions
- Shoulder Impingement, Shoulder Pain, Adhesive Capsulitis, Rotator Cuff Tears
- Trial name
- PPCS (NCT04901780)
- Testing
- pragmatic posterior capsular stretch, cross body stretch
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Helping Hand Institute of Rehabilitation Sciences
Dupuytren Contracture
Is wGRS Associated With DD Recurrence?
Rationale: Retrospectively reviewing the participants of the GODDAF database, revealed a significant association between the weighted genetic risk score and Dupuytren disease recurrence.
- Trial name
- NCT02983162
- Where
- Netherlands
- Volunteers
- 427 people
- Sponsor
- University Medical Center Groningen
Capsular Contractures
Prevention of Capsular Contracture Using Trental and Vitamin E
The main purpose of this research study is to determine if the use of Trental and Vitamin E will decrease the incidence and severity of contractures (shrinking and or hardening of tissue surrounding the implant) associated with…
- Trial name
- NCT01082003
- Testing
- Trental
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Legacy Health System
Dupuytren Contracture, Dupuytren Disease of Palm and Finger
Treatment of Dupuytren's Disease With Minimal Invasive Surgery and VIVOSORB® Resorbable Implant Device
Dupuytren's disease is a progressive fibroproliferative condition of the hand which progresses in 20% of patients into a serious condition.
- Trial name
- Vivosorb (NCT03741764)
- Testing
- Vivosorb
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- prof. dr. Ilse Degreef
Breast Cancer Females, Breast Reconstruction
Influencing Factors and Mechanisms of Capsular Contracture After Prosthesis Reconstruction in Patients With Breast Cancer
The aim of this study is to evaluate the aesthetic outcomes in immediate implant-based breast reconstruction following breast mastectomy surgery.
- Trial name
- NCT07419971
- Testing
- synthetic mesh
- Where
- China
- Volunteers
- 300 people
- Sponsor
- West China Hospital