Clinical trials: Contraction
Tachycardia, Paroxysmal Supraventricular Tachycardia
AI-Based Differential Diagnosis and Localization of Tachycardia Using ECG: Multicenter Registry (EP-AI ASSIST)
This multicenter retrospective study aims to develop, validate, and clinically apply an artificial intelligence (AI)-powered electrocardiography (ECG) algorithm for the diagnosis and prognostic prediction of cardiovascular…
- Conditions
- Tachycardia, Paroxysmal Supraventricular Tachycardia, Wolff-Parkinson-White Syndrome, Premature Ventricular Contractions
- Trial name
- EP-AI ASSIST (NCT07859020)
- Testing
- AI-based ECG Diagnostic and Localization Algorithm
- Where
- South Korea
- Volunteers
- 10,000 people
- Sponsor
- Inha University Hospital
ACL - Anterior Cruciate Ligament Rupture, Activation Failure
Activation Failure of Knee Extensors After Anterior Cruciate Ligament Rupture Depending on the Contraction Mode
The primary objective of the study is to evaluate the impact of ACL injury and ACL reconstruction on voluntary activation during maximal voluntary contraction (measured by neurophysiological parameters) according to the…
- Conditions
- ACL - Anterior Cruciate Ligament Rupture, Activation Failure, Contraction Mode
- Trial name
- QUADFAIL (NCT06783062)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- La Tour Hospital
Premature Atrial Contractions, Premature Ventricular Contractions
The MARY-JANE Cannabis and Heart Rhythm Trial
Despite recreational cannabis now being legal in 23 states, where more than 100 million Americans reside, studies on the actual health effects are limited.
- Trial name
- NCT06021613
- Testing
- Randomized instructions
- Where
- 2 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Multiple Sclerosis, Poststroke/CVA Hemiparesis
Voluntary Activation During Isokinetic Contractions in Subjects with Neuromotor Disorders
Activation is the amount of voluntary recruitment of a muscle during voluntary contraction. Full activation implies the recruitment of all muscle fibres at their tetanic frequency.
- Conditions
- Multiple Sclerosis, Poststroke/CVA Hemiparesis, Parkinson Disease, Knee Impairment
- Trial name
- ATTILA (NCT04607174)
- Testing
- Pathologic group
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Auxologico Italiano
Preterm Birth
Pilot Study to Evaluate a Prototype Electronic Uterine Inhibitor to Prevent Preterm Contractions
Use an electrical-inhibition (EI)/uterine pacemaker device similar to an electrical heart pacemaker to deliver a weak electrical current to the human uterus that will rapidly and safely inhibit the unwanted premature uterine…
- Trial name
- NCT00212446
- Testing
- Electrical Intervention (EI)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Infertility, Endometrial Peristalsis
Association Between Peri-Transfer Endometrial Peristalsis And Live Birth In Modified Natural Cycle Frozen Embryo Transfer: A Prospective Cohort Study
The uterus is a dynamic muscular organ that undergoes rhythmic, wave-like contractions known as endometrial peristalsis or endometrial waves.
- Conditions
- Infertility, Endometrial Peristalsis, Uterine Contraction, Endometrial Waves
- Trial name
- EPFE (NCT07358468)
- Testing
- Endometrial peristalsis and hormone measurements
- Where
- 2 sites in Vietnam
- Volunteers
- 384 people
- Sponsor
- Mỹ Đức Hospital
Heart Block, Heart Block Complete
Effect of Site of Right Ventricular (RV) Pacing on RV Function, Left Ventricular (LV) Dyssynchrony and Contraction Efficiency
To evaluate RV systolic function and LV mechanical dyssynchrony and function in different lead position in the RV during permanent pacemaker implantation by using speckle tracking echocardiography (STE) and 3D volumetric ejection…
- Conditions
- Heart Block, Heart Block Complete, Systolic Function
- Trial name
- NCT06636851
- Testing
- Pacemaker and defibrillator
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- South Valley University
Type 2 Diabetes Mellitus
Impact of Muscle and Tendon Dysfunction in People With Type 2 Diabetes Mellitus
Diabetes is a chronic-degenerative metabolic disorder that has reached pandemic proportions mainly because of the increasing incidence and prevalence of type 2 diabetes mellitus (T2D).
- Trial name
- T2D_MTU (NCT05585502)
- Testing
- Training (minute oscillation stretching)
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Healthy
Reference Values for the One Repetition Maximum Test of Knee Extensors for Brazilians.
Muscle strength is important for health and can affect how well people live, even increasing the risk of death in adults and older people.
- Trial name
- NCT06648421
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Premature Ventricular Contraction
Remote Magnetic Versus Manual Navigation-guided Ablation for Non-outflow Tract Premature Ventricular Contractions: a Prospective, Randomized, Controlled Trial
This prospective, randomized, controlled trial is designed to compare the safety and efficacy of remote magnetic navigation-guided ablation for ventricular premature complexes arising from non-outflow tracts with manual control…
- Trial name
- NCT04519112
- Testing
- Catheter Ablation
- Volunteers
- 200 people
- Sponsor
- Ruijin Hospital
Myocarditis, Premature Ventricular Contractions
Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry
To assess potential link between unrecognized myocardial inflammation (myocarditis) and premature ventricular contractions (PVCs) associated with and without reduced Left ventricular ejection fraction (LVEF) through comprehensive…
- Conditions
- Myocarditis, Premature Ventricular Contractions, Ventricular Tachycardia (VT)
- Trial name
- MAVERIC (NCT05158751)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Neonatal Respiratory Distress
The Role of ARTificial Uterine CONtractions in Perinatal Respiratory Morbidity of Term Infants Delivered by Elective Caesarean Section
In this study, the investigators aim to investigate if artificial uterine contractions prior to elective caesarean section delivery may have an impact on the respiratory morbidity of term neonates.
- Trial name
- ARTCON (NCT03899597)
- Testing
- Oxytocin, Normal saline
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Institute for the Care of Mother and Child, Prague, Czech Republic
Pelvic Floor Disorders
Pelvic Floor Muscle Contraction During Hypopressive Exercise in Women With Pelvic Floor Dysfunction
The purpose of this randomized controlled trial is to compare the effectiveness of different modalities of hypopressive exercise in women with pelvic floor dysfunction.
- Trial name
- HIPOSPFD (NCT04336150)
- Testing
- Hypopressive exercises, Hypopressive maneuver, Hypopressive exercises plus pelvic floor muscle contraction
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Alcala
Muscle Strength, Resistance Training
Effects of Blood Flow Restriction vs. High-Load Resistance Training on Arm Strength
This study investigated the effects of low-load resistance training combined with blood flow restriction (BFRT) compared to traditional high-load resistance training on arm muscle strength and isokinetic contraction parameters in…
- Conditions
- Muscle Strength, Resistance Training, Blood Flow Restriction
- Trial name
- BFRT-ARM (NCT07462520)
- Testing
- Low Load Blood Flow Restriction Training, High Load Resistance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Gazi University
Ventricular Tachyarrhythmia, Ventricular Arrythmia
Ventricular Catheter Ablation Study (VCAS)
This is a prospective safety and feasibility study to evaluate the safety of the FieldForce™ Ablation system in patients with ventricular arrhythmia divided into two groups: VT (VCAS-I) and frequent premature ventricular complex…
- Conditions
- Ventricular Tachyarrhythmia, Ventricular Arrythmia, PVC - Premature Ventricular Complex, PVC - Premature Ventricular Contraction
- Trial name
- VCAS (NCT06203262)
- Testing
- FieldForce™ Ablation System Ventricular Tachycardia, FieldForce™ Ablation System Premature Ventricular Contractions
- Where
- 2 sites in Czechia
- Volunteers
- 34 people
- Sponsor
- Field Medical
Premature Ventricular Contraction
Efficacy and Safety of Sulcardine Sulfate Tablets in Patients With Premature Ventricular Contractions
Arrhythmia is a common disease that may be caused by various cardiovascular diseases. According to statistics, 500,000 people die of severe arrhythmia every year in China, In the United States, approximately 540,000 patients die…
- Trial name
- NCT01235156
- Where
- 2 sites in China
- Volunteers
- 36 people
- Sponsor
- Jiangsu Furui Pharmaceuticals Co., Ltd
Constipation by Outlet Obstruction
Defecation Patterns in Constipated Patients
Chronic constipation (CC) is a common condition that affects up to 25% of the population in North America. It poses a major burden on the healthcare cost.
- Trial name
- NCT04903470
- Testing
- Bisacodyl, Atropin
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- The California Medical Innovations Institute, Inc.
Urinary Incontinence
Pelvic Floor Muscle Contraction in Response to Different Verbal Instructions in Women With Urinary Incontinence
The aim of this study is to investigate which verbal instruction will lead to the most efficient contraction of pelvic floor muscles (PFM) in patients with urinary incontinence.
- Trial name
- NCT03940794
- Testing
- Verbal instruction
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Ariel University
Forehead Rhytid Complex, Glabellar Rhytid Complex
Treatment of Forehead/Glabellar Rhytide Complex With Botulinum Toxin A Injection
This cross-over design study will evaluate the onset of action, efficacy, and duration of botulinum toxin A treatment on forehead/glabellar rhytid complexes with and without subsequent muscle contraction.
- Trial name
- NCT01688076
- Testing
- Botulinum Toxin A
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Dehydration, Weight Loss
Effect of Dehydration on Sleep Quality, Cognitive Skills, and Electromyographic Responses in Combat Athletes
This study examines the effects of rapid dehydration-induced weight loss on combat athletes' sleep quality, cognitive skills, and isokinetic strength performance.
- Conditions
- Dehydration, Weight Loss, Weight Cycling, Sleep
- Trial name
- NCT07118904
- Testing
- Rapid weight loss through dehydration
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University