Clinical trials: Continuous Glucose Monitoring
Gestational Diabetes, Hyperglycemia
Early Investigation of Glucose Monitoring After Gestational Diabetes Pilot
One third of women with gestational diabetes (GDM), diabetes diagnosed during pregnancy, have abnormal glucose levels within 3 years after pregnancy, but follow up is low.
- Trial name
- ENGAGED (NCT06184373)
- Testing
- Continuous glucose monitor, Oral Glucose Tolerance Test, Hemoglobin A1c
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Preterm Birth, Hyperglycemia
Blood Glucose in Pregnant Non-diabetic Women During Treatment With Betamethasone for Fetal Lung Maturation
In case of threatening preterm birth, it is standard to recommend treatment with betamethasone to accelerate fetal lung maturation.
- Conditions
- Preterm Birth, Hyperglycemia, Neonatal Hypoglycemia, Threatened Preterm Labor
- Trial name
- NCT06794307
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- University of Aarhus
Type 2 Diabetes, Kidney Disease
Efficacy of the Use of Real-time Continuous Glucose Monitoring on Glycemic Control in Patients With Type 2 Diabetes and Stage 3 and 4 Chronic Kidney Disease.
Rationale: Glucose control in patients with kidney disease is challenging, as traditional metrics can be unreliable and there is a high risk of hypoglycemia (low blood sugar).
- Conditions
- Type 2 Diabetes, Kidney Disease, CGM, Time in Range
- Trial name
- NCT07668219
- Testing
- Real time continuos glucose monitoring, self blood glucose monitoring
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Hospital Universitario San Ignacio
Diabetes Mellitus, Type 2
Relationship Between HbA1c, Fasting Plasma Glucose, Post-prandial Glucose and Other Measures of Glycemic Control
This study aims to evaluate relative contributions of fasting plasma glucose and postprandial glucose at various HbA1c levels using 6-day CGM.
- Trial name
- NCT02117154
- Testing
- 6-day Continuous Glucose Monitoring System
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- University of Malaya
Type 1 Diabetes Mellitus
Long-term Observation Of Patient Engagement in Automated Insulin Delivery
The purpose of this study is to assess the long-term evolution of patient interaction with the CONTROL-IQ (Tandem™) hybrid closed-loop (HCL) system in individuals with type 1 diabetes over 24 months.
- Trial name
- LOOPED (NCT06858475)
- Testing
- CONTROL-IQ (Tandem™)
- Where
- France
- Volunteers
- 453 people
- Sponsor
- Centre Hospitalier Sud Francilien
Blood Glucose Decrease During and After Defined Individual Exercise in T1DM
Exercise in Type 1 Diabetes Mellitus
Background: During and after exercise there is a twofold stimulation of glucose transporter type 4 in type 1 diabetes mellitus (T1DM) caused by an exogenous insulin injection and muscle contraction.
- Trial name
- ExT1DM (NCT02075567)
- Testing
- Experimental
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Type 2 Diabetes, Currently Taking Metformin
Using Continuous Glucose Monitoring to Understand the Glycemic Impact of Food
This study will look at the impact that meals have on blood glucose (sugar) levels. Subjects will be asked to use a Continuous Glucose Monitoring System (CGM), which monitors glucose levels continuously.
- Trial name
- NCT00818077
- Testing
- Continuous Glucose Monitoring of Carbohydrate Intake
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- HealthPartners Institute
Type 1 Diabetes Mellitus
Feasibility Study of Closed Loop Control in Type 1 Diabetes Using Heart Rate Monitoring as an Exercise Marker
The purpose of this study is to see if the Artificial Pancreas Platform (AP Platform = Cell Phone + Closed Loop Control) can successfully control blood sugar in people with type 1 diabetes mellitus on insulin pump therapy in a…
- Trial name
- NCT01582139
- Testing
- Heart rate informed SSM+HMM
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Virginia
Type 2 Diabetes
Clinical Decision Support With Continuous Glucose Monitoring Data for Managing Type 2 Diabetes
The goal of this project is to see if an electronic health record (EHR)-based smart order set with continuous glucose monitoring data to provide decision support can improve blood sugar management in people with type 2 diabetes…
- Trial name
- TRACTION-PC (NCT07394075)
- Testing
- Continuous Glucose Monitoring Clinical Decision Support
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- HealthPartners Institute
Healthy, Type 2 Diabetes Mellitus
Type 2 Diabetes Glucose Biomarker Study With a Continuous Glucose Monitoring System
Current gold standard methodologies for diagnosing type 2 diabetes (T2D) or prediabetes can be unreliable and inaccurate, and require the need for multiple different tests for comparison.
- Trial name
- NCT04529239
- Testing
- Abbott Freestyle Libre Pro
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Klick Inc.
Type 1 Diabetes Mellitus
Mixed Meal Test in Type 1 Diabetes on Insulin Pump Therapy: Optimization of Artificial Pancreas
BACKGROUND. Optimal glucose control can prevent/relent tissue damage in patients with type 1 diabetes mellitus (T1DM). Ongoing efforts aim at developing closed loop control (CLC) algorithms linking subcutaneous continuous glucose…
- Trial name
- NCT02003274
- Testing
- Clamp-Mixed Meal, IVGTT-Mixed Meal Arm
- Where
- 2 sites in Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Prediabetes
Returning to Normoglycemia With Targeted Use of Real-time CGM Data and Nutrition-focused Lifestyle Changes
The purpose of the ReTURN study is to understand how glycemia, specifically percent of time above 140 mg/dL (TA140), changes over time in people who are randomized to receive either continuous glucose monitoring (CGM)-guided care…
- Trial name
- RETURN (NCT07832474)
- Testing
- CGM-guided care
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- HealthPartners Institute
type1diabetes
Accuracy of a Continuous Ketone Monitoring (CKM) System in Individuals With Type 1 Diabetes on Insulin Pump Therapy.
The goal of this 14-day randomized pilot trial is to assess the accuracy of a continuous ketone monitoring (CKM) system when compared to standard point-of-care capillary ketone monitors in individuals with type 1 diabetes on…
- Trial name
- CKM 1 (NCT06420518)
- Testing
- Ketogenic diets, 8-hour insulin-suspension period
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- McGill University
Type 2 Diabetes
Continuous Glucose Monitoring Following Hospital Discharge
In this 12-week prospective observational cohort study, hospitalized insulin-requiring patients with T2D will receive a Dexcom continuous glucose monitor (CGM) to wear post-hospital discharge.
- Trial name
- NCT05360056
- Testing
- DexCom G6
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Kathleen Dungan
Gestational Diabetes Mellitus in Pregnancy
The CGMS in GDM Labor and Delivery Study
Glucose control during labor is important for both fetus and mother. During labor and delivery, the goal is to maintain the sugars in the normal range as safely as possible as increased blood sugars 4-6 h prior to delivery leads…
- Trial name
- CGMSGDMLABOR (NCT05067075)
- Testing
- Blinded CGM
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Woman's
Glucose Metabolism Disorders, Dietary Habits
Dietary Impact on Continuous Glucose Monitoring
Cardiorespiratory fitness (CRF), also known as "exercise capacity", is the capacity of respiratory and circulatory systems to supply oxygen to skeletal muscle during exercise for the generation of energy.
- Conditions
- Glucose Metabolism Disorders, Dietary Habits, Pediatric ALL, Adult ALL
- Trial name
- NCT05845827
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Diabetes Mellitus Type 1
A Study of the Rules for Insulin Dosing in Patients Using Multiple Daily Injections
This study will be conducted in subjects with Type 1 diabetes mellitus on multiple daily insulin injections to determine the correct insulin dosing formulas. Subjects will be evaluated using continuous glucose monitoring.
- Trial name
- NCT01045954
- Testing
- Lispro Insulin and glargine insulin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Diabetes Care Center
Diabetes Mellitus, Insulin-Dependent
Pilot Study of the Navigator Continuous Glucose Monitor
This study is being done to find out how accurate the Navigator continuous glucose monitor is in children. It is also being done to see if use of the Navigator can improve blood sugar control and help prevent low blood sugar…
- Trial name
- NCT00166673
- Testing
- FreeStyle Navigator Continuous Glucose Monitoring System
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Jaeb Center for Health Research
Primary Adrenal Insufficiency, Ramadan Fasting
Risks of Ramadan Fasting in Patients With Primary Adrenal Insufficiency Treated With Prednisolone.
In primary adrenal insufficiency (PAI), there is a risk of hypoglycemia and dehydration. These risks seem to be increased during intermittent fasting.
- Conditions
- Primary Adrenal Insufficiency, Ramadan Fasting, Prednisolone, Continuous Glucose Monitoring
- Trial name
- NCT07367425
- Testing
- Ramadan fasting
- Where
- Tunisia
- Volunteers
- 35 people
- Sponsor
- Hopital La Rabta
Type 2 Diabetes
Pharmacist-led Continuous Glucose Monitoring
This is a pilot study. The goal of this prospective cohort study is to determine impact of pharmacist-led continuous glucose monitoring on glycemic control and health behavior change in people with type 2 diabetes.
- Trial name
- NCT06572306
- Testing
- FreeStyle Libre 2/Libre 3+ Continuous Glucose Monitor
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of South Florida