Clinical trials: Continuous Glucose Monitoring
Insulin Resistance
Impact of Starch Digestibility on Glycemic Variability and Control, Cardiometabolic and Inflammatory Profiles, Microbiota and Intestinal Health in Subjects With Insulin Resistance
To study the potential impact of a diet rich in both Slowly Digestible Starch (SDS) and Resistant Starch (RS), we propose a 2-month nutritional intervention study in which we will study the evolution of carbohydrate variability…
- Trial name
- GLYMICARE (NCT07408479)
- Testing
- Balanced diet high in Slowly Digestible Starch and Resistant Starch, Balanced diet low in Slowly Digestible Starch and Resistant Starch
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mondelēz International, Inc.
Blood Glucose Decrease During and After Defined Individual Exercise in T1DM
Exercise in Type 1 Diabetes Mellitus
Background: During and after exercise there is a twofold stimulation of glucose transporter type 4 in type 1 diabetes mellitus (T1DM) caused by an exogenous insulin injection and muscle contraction.
- Trial name
- ExT1DM (NCT02075567)
- Testing
- Experimental
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Prediabetes
Early Precise Identification and Intervention Strategies for Individuals at High Risk of Prediabetes
Prediabetes significantly increases the risk of developing diabetes, cardiovascular and cerebrovascular diseases, tumors, and dementia.
- Trial name
- NCT07386756
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Gestational Diabetes Mellitus
Myo-inositol Administration in Gestational Diabetes
Myo-Inositol is an insulin sensitizing agent that ameliorate the insulin resistance in women affected by gestational diabetes (GDM), but there is no information about the effect on the glucose profile.
- Trial name
- NCT00734448
- Testing
- myo-inositol
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Messina
Diabetic Ketoacidosis, Type 1 Diabetes Mellitus
Early Glargine (Lantus) in DKA Management in Children With Type 1 Diabetes
A frequent complication in the management of diabetic ketoacidosis (DKA) in children with type 1 diabetes is rebound hyperglycemia (blood glucose over 180 mg/dL) which increases the risk of re-developing DKA and can lengthen the…
- Trial name
- NCT03107208
- Testing
- Glargine, Continuous Glucose Monitor (Abbott FreeStyle Libre Pro)
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pregnancy Preterm, Neonatal Hypoglycemia
Continuous Glucose Monitoring of Late Preterm Birth After Corticosteroids
Women undergoing late preterm birth are at high risk of delivering a newborn with neonatal hypoglycemia. The investigators plan to monitor interstitial glucose levels prior to delivery in these women in order to develop a better…
- Conditions
- Pregnancy Preterm, Neonatal Hypoglycemia, Prematurity
- Trial name
- NCT03738293
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix
Type 1 Diabetes
Timing of Insulin Before Meals Everyday
The inclusion of "Timing of premeal insulin administration (Timing)" in an Intensive Insulin Therapy regimen will reduce A1C by an average of 1% in type 1 diabetic patients who have initial A1C's between 7.0% and 9.0%.
- Trial name
- TIME (NCT00789945)
- Testing
- Control, Study Arm B
- Where
- 2 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Type 2 Diabetes, PreDiabetes
Evaluation of Exercise Application Technology in Adolescents
The purpose of the study is to evaluate the use of an exercise phone application and a continuous glucose monitor and their impact on metabolic disease in adolescents with obesity, prediabetes and Type 2 diabetes.
- Conditions
- Type 2 Diabetes, PreDiabetes, Obesity
- Trial name
- NCT05720377
- Testing
- continuous glucose monitor (Freestyle Libre
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Diabetes Mellitus, Type 1
Study Comparing Prandial Insulin Aspart vs. Technosphere Insulin in Patients With Type 1 Diabetes on Multiple Daily Injections: Investigator-Initiated A Real-life Pilot Study-STAT Study
This is an investigator-initiated, prospective, randomized, multicenter, parallel, open-label, pilot clinical trial evaluating the efficacy of TI for PPBG, PPGE, and time-in-range on CGM download in patients with T1D.
- Trial name
- STAT (NCT03143816)
- Testing
- Technosphere insulin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Steroid-Induced Diabetes, Diabete Type 2
Predictive Factors and Monitoring Strategies in Steroid-Induced Diabetes
Glucocorticoids are widely used in the management of autoimmune, inflammatory and neoplastic conditions. However, they are associated with significant metabolic effects, including steroid-induced diabetes (SID).
- Conditions
- Steroid-Induced Diabetes, Diabete Type 2, Steroid Induced Hyperglycemia
- Trial name
- NCT07190378
- Where
- Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Healthy
Effects of a Novel Supplement on Glycemic Variability Measured by Continuous Glucose Monitoring
This is a two-cohort, crossover pilot study to determine interstitial glucose levels coincident with the consumption of a novel carbohydrate blocking supplement.
- Trial name
- NCT05832463
- Testing
- Carbohydrate blocking supplement (CBS)
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- dōTERRA International
Carbohydrate Metabolism, Lipid Metabolism
Nutrient Timing in Connection to Evening Exercise
Physical exercise (PE) significantly influences insulin sensitivity (IS), glucose control and overall metabolic health. While PE effectively enhances IS and glucose regulation, the timing of nutrient intake, before and after…
- Conditions
- Carbohydrate Metabolism, Lipid Metabolism, Blood Glucose, Oral Glucose Tolerance Test
- Trial name
- NCT06400836
- Testing
- Carbohydrate timing - carbohydrate intake before or after exercise
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Diabetes Mellitus, Glucose
The GLOW Study - The YANG System
This is an open label, interventional, monocentric, prospective early feasibility study, designed to evaluate the safety of implant and short-term integration into the tissue of the YANG sensor.
- Trial name
- NCT04782934
- Testing
- The YANG SENSOR is an active implantable device, for Real Time Continuous Glucose, Lactate and Ketone Measurement
- Where
- Belgium
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Indigo Diabetes NV
Gestational Diabetes
A Study on the Use of Real -Time Continuous Glucose Monitoring (RT-CGM) in Gestational Diabetes
The purpose of this study is to examine whether RT-CGM (real time continuous glucose monitoring) use improves glucose control, maternal outcomes, and fetal outcomes in patients diagnosed with gestational diabetes.
- Trial name
- NCT04803357
- Testing
- Continuous glucose monitor
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Washington
Healthy
Non-invasive Measurement of Glucose with Advanced Spectroscopy Techniques and Machine Learning Models
Primary aim of this pilot study is to provide evidence for a non-invasive, continuous, and transcutaneous measurement method to determine blood glucose levels robustly and accurately.
- Trial name
- NCT06406075
- Testing
- Lab demo 1.0
- Where
- Switzerland
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Liom Health AG
Postprandial Glucose Response, Glycaemic Index
Determination of Postprandial Glycemic Responses by Continuous Glucose Monitoring in a Real-World Setting
Self-monitoring of blood glucose using capillary glucose testing has a number of shortcomings compared to continuous glucose monitoring (CGM).
- Conditions
- Postprandial Glucose Response, Glycaemic Index, Continous Glucose Measurement
- Trial name
- NCT04147273
- Testing
- Determination of postprandial glucose response by continuous glucose measurement after consuming different carbohydrate containing foods
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- West German Center of Diabetes and Health
Cardiometabolic Risk Factors
Metabolic Wellness and CGM
The primary objective of this study is to determine the impact of participating in an online lifestyle intervention program on glycemic control as measured by Continuous Glucose Monitoring (CGM), with the primary outcome being…
- Trial name
- NCT06790472
- Testing
- Online Lifestyle Intervention, Continuous Glucose Monitoring
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- David Kerr
Diabetes Mellitus, Type 1
Type 1 Diabetes and the Brain in Children
The investigators have previously studied a group of young children with T1D using brain MRI, age-appropriate neurocognitive testing and continuous glucose monitoring, followed for 18 months.
- Trial name
- NCT02351466
- Testing
- Observational
- Where
- 5 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Pre-diabetes
Continuous Glucose Monitoring in Prediabetes
The objective of this project is to develop a behavioral intervention that combines wearable continuous glucose monitoring (CGM) with smartphone feedback and educational video clips generated by artificial intelligence (AI)…
- Trial name
- G1 (NCT06472297)
- Testing
- The continuous glucose monitoring system
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Pregnancy
The Early and Late Contribution of Fasting and Postprandial Triglycerides on Newborn Subcutaneous and Intrahepatic Fat in Pregnancy
This study plans to learn more about how triglyceride levels in pregnancy affect newborn fat mass. Obesity in pregnancy, in the absence of gestational diabetes, is now the most common cause of large-for-gestational-age infants…
- Trial name
- NCT04394806
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver