Clinical trials: Contact Lens Comfort
Myopia, Hyperopia
Evaluation of the Effectiveness of Two Marketed Multi-Purpose Solutions for Silicone Hydrogel Contact Lenses - Study 2
The purpose of this study was to evaluate the performance of Opti-Free® PureMoist® Multi-purpose Disinfecting Solution (MPDS) compared to AMO RevitaLens OcuTec® MPDS (US brand name)/COMPLETE RevitaLens (Europe brand name) in…
- Conditions
- Myopia, Hyperopia, Contact Lens Comfort
- Trial name
- NCT01684046
- Testing
- Opti-Free® PureMoist® MPDS, RevitaLens MPDS, Habitual Contact Lenses
- Volunteers
- 196 people
- Sponsor
- Alcon Research
Dry Eye
The Effect of Xiidra on Comfort and Dryness in Symptomatic Contact Lens Wearers
The purpose of this study to evaluate changes in comfort and dryness in symptomatic contact lens (CL) wearers after using Xiidra (lifitegrast 5.0% ophthalmic solution) for 12 weeks.
- Trial name
- COLLIE (NCT04297618)
- Testing
- Xiidra
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Visual Acuity
Evaluation of Comfort for Two Marketed Daily Disposable Contact Lenses
This study is a 2-phase adaptive approach utilizing a 2×2 crossover design. The study lenses will be worn in a bilateral fashion for a period of approximately 1-week each.
- Trial name
- NCT04968925
- Testing
- ACUVUE Oasys 1-Day, Precision 1
- Where
- 10 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens Wear
Subjective Comfort With Multipurpose and Hydrogen Peroxide Lens Care Solutions in Soft Contact Lens Wearers
The purpose of this study was to assess comfort in soft contact lens wearers.
- Trial name
- NCT01164865
- Testing
- OPTI-FREE RepleniSH multipurpose disinfecting solution, Clear Care contact lens care system, Contact lenses
- Volunteers
- 78 people
- Sponsor
- Alcon Research
Corneal Staining
Comfort Evaluation of a New MPS vs. Replenish in Contact Lens Patients
To compare corneal staining after contact lens instillation with a new MPS vs. RepleniSH
- Trial name
- NCT00518700
- Testing
- new MPS, RepleniSH
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Innovative Medical
Refractive Error, Myopia
Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
The purpose of this study was to compare lens comfort on Day 30 for Air Optix® lenses cared for with OPTI-FREE® PureMoist® (OFPM) Multi Purpose Disinfecting Solution (MPDS) compared to Acuvue® Oasys® lenses cared for with…
- Conditions
- Refractive Error, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01809197
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS)
- Volunteers
- 387 people
- Sponsor
- Alcon Research
Eye Strain
To Evaluate the Performance of Total 30 (Lehifilcon A) Contact Lenses in Patients Using Digital Devices for Greater Than 8 Hours Per Day 5 Days Per Week Based on Subjective Reported Data.
To evaluate the performance of Total 30® (lehfilcon A) contact lenses in patients using digital devices for greater than 8 hours per day 5 days per week based on subjective reported data.
- Trial name
- NCT06317038
- Testing
- Total 30 Contact Lens
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Tauber Eye Center
Corneal Staining
Short-Term Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
An investigational multi-purpose solution (MPS)was clinically evaluated against Biotrue MPS at specific time points over the course of four days. The study was conducted with PureVision lenses.
- Trial name
- NCT01240122
- Testing
- Biotrue MPS, Investigational MPS
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Contact Lens Complication
A Clinical Study Comparing the Comfort of Three Commercially Available Contact Lenses
The purpose of this study is to compare the comfort of three commercially available contact lenses.
- Trial name
- NCT02298400
- Testing
- Acuvue® Oasys® Lenses (senofilcon A), 30-Day Bausch + Lomb PureVision (balafilcon A), Clariti® 1-Day (Somofilcon A)
- Where
- United States
- Sponsor
- ORA, Inc.
Visual Acuity, Contact Lens Comfort
Assessment of Comfort & Ocular Surface Parameters w Novel Designs of Daily Disposable Silicone Hydrogel Contact Lenses
A comparison of two lens designs manufactured in the same material. The hypothesis is the subjectively rated performance of comfort, vision and lens handling will be better with the modified design compared to the initial design
- Trial name
- BASS (NCT03454542)
- Testing
- Menicon Modified Lens Design
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Dry Eye, Dry Eye Syndromes
Assessment of Tear Production, Corneal Staining, and Comfort Level Wearing Different Types of Contact Lenses
This research assesses the tear performance of five distinct types of soft contact lenses commonly found in the market. The study involves contact lens participants, all of whom are students enrolled at UKM.
- Conditions
- Dry Eye, Dry Eye Syndromes, Contact Lens-induced Corneal Fluorescein Staining
- Trial name
- NCT06351410
- Testing
- Eye Wearing Contact Lens
- Where
- Malaysia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Contact Lenses, Presbyopia
Clinical Performance of Verofilcon A Toric Contact Lenses
The goal of this clinical trial is to [primary purpose: is to determine if Total30 Multi focal toric conntact lensesare comfortable and the willigness for those who have previously worn reusable toric contact lenses are willing…
- Trial name
- NCT07586982
- Testing
- Total 30 multi foric contact lenses
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Dry Eye Syndromes
A Pilot Study on the Use of a Sensory Panel to Assess Comfort Between Three Different Contact Lenses
As new contact lens products continue to be developed and improved, it's becoming harder for some individuals to tell whether one product is different from another.
- Trial name
- NAISMITH (NCT01840787)
- Testing
- balafilcon A (8.6), balafilcon A (8.3), senofilcon A
- Where
- Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Contact Lens Complication, Astigmatism
T30 for Astigmatism in Digital Device Users
This study aims to determine if Total30 lenses for astigmatism can be successfully fit in participants who are heavy digital device users.
- Conditions
- Contact Lens Complication, Astigmatism, Refractive Errors
- Trial name
- T30FA (NCT06266728)
- Testing
- Total30 for Astigmatism Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Adverse Reaction to Contact Lens Solution
The Clinical and Subjective Performance of Three Different MPDS With Silicon Hydrogel Lenses
The purpose of the clinical investigation is to assess the clinical and subjective performance of three novel multipurpose disinfecting solutions (MPDS) in daily wear with two silicone hydrogel contact lenses (Lotrafilcon B and…
- Trial name
- NCT01665612
- Testing
- Contact lens care solution
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Finnsusp Ltd.
Myopia, Astigmatism
Prospective Study of an Investigational Toric Soft Contact Lens
The purpose of this study was to demonstrate substantial equivalence of an investigational toric soft contact lens to the commercially available Focus® DAILIES® Toric soft contact lens when worn in a daily wear, daily disposable…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01461811
- Testing
- Nelfilcon A toric contact lenses (with comfort additives), Nelfilcon A toric contact lenses
- Volunteers
- 154 people
- Sponsor
- CIBA VISION
Eyelid Diseases
Bandage Contact Lenses Versus Eye Patching of Müller's Muscle-conjunctival Resection
Patients with blepharoptosis who are treated with Müller's muscle-conjunctival resection (MMCR) may experience postoperative pain and discomfort related to the suture material on the palpebral conjunctiva.
- Trial name
- NCT04554329
- Testing
- bandage contact lens
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Myopia, Hyperopia
Evaluation of the Effectiveness of Two Marketed Multi-Purpose Solutions for Silicone Hydrogel Contact Lenses - Study 1
The purpose of this study was to evaluate the performance of Opti-Free® PureMoist® Multi-Purpose Disinfecting Solution (MPDS) compared to Biotrue™ Multipurpose Solution (MPS) in silicone hydrogel contact lens wearers.
- Conditions
- Myopia, Hyperopia, Contact Lens Comfort
- Trial name
- NCT01684033
- Testing
- Opti-Free® PureMoist® MPDS, Biotrue™ MPS, Habitual contact lenses
- Volunteers
- 207 people
- Sponsor
- Alcon Research
Myopia, Refractive Error
Multi-Center Clinical Evaluation of Two Daily Disposable Contact Lenses
The purpose of this study is to compare the subjective performance of two daily disposable contact lenses with respect to comfort and handling.
- Trial name
- NCT01898260
- Testing
- Ultrafilcon B contact lens, Stenfilcon A contact lens
- Where
- United Kingdom
- Volunteers
- 89 people
- Sponsor
- Alcon Research
Contact Lens Comfort
Acuvue Oaysis Contact Lens Wearers Being Refit Into P7 Contact Lenses
Determine the likelihood of successfully refitting a satisfied AOA CL wearers into P7A CLs
- Trial name
- NCT06955403
- Testing
- Precision 7 contact lenses
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry