Clinical trials: Contact Lens Care
Myopia
An Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues
The purpose of this study was to assess and compare the effect of the repeated usage of 2 different care systems (one hydrogen peroxide based cleaning and disinfecting system and one PHMB containing multipurpose system) with…
- Trial name
- ID11-56 (NCT01594294)
- Testing
- AOSEPT® Plus contact lens solution, ReNu MultiPlus® contact lens solution, Etafilcon A contact lenses
- Volunteers
- 100 people
- Sponsor
- Alcon Research
Contact Lens Wear
Investigational Multi-purpose Contact Lens Care Solution.
This study compares an investigational contact lens care multi-purpose solution to a currently marketed multi-purpose solution.
- Trial name
- NCT01055613
- Testing
- Vistakon Investigational Multi-Purpose Solution I, ReNu MultiPlus Multi-Purpose Solution
- Where
- 15 sites in United States
- Volunteers
- 312 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens Care
Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues
The purpose of this study was to assess and compare the effect of the repeated usage of two different contact lens care systems (one hydrogen peroxide-based cleaning and disinfecting system, and one polyaminopropyl biguanide…
- Trial name
- NCT01494818
- Testing
- Hydrogen peroxide-based contact lens care system, PHMB-containing contact lens solution, Soft contact lenses
- Volunteers
- 79 people
- Sponsor
- Alcon Research
Myopia
Study Intended to Evaluate the Safety and Effectiveness of a Johnson & Johnson Vision Care Inc, (JJVCI) Contact Lens for Use on an Extended-wear Basis for up to 7 Days (6 Nights).
Study in the US intended to evaluate the safety and effectiveness of a Johnson \& Johnson Vision Care Inc, (JJVCI) contact lens for use on an extended-wear basis for up to 7 days (6 nights).
- Trial name
- NCT00241280
- Testing
- etafilcon A, galyfilcon A
- Where
- 25 sites in United States
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
A Clinical Evaluation of Two Contact Lenses Used With Three Care Systems
The objective of the study was to compare the clinical performance of the two contact lenses when used in combination with three care systems.
- Trial name
- NCT04195581
- Testing
- comfilcon A, fanfilcon A
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Error
Evaluation of a Johnson & Johnson Vision Care Investigational Contact Lens Compared to a Marketed Monthly Replacement Contact Lens
Randomized, double-masked, controlled, 2-arm parallel group, multi-site, 3-month dispensing study of Johnson \& Johnson Vision Care, Inc.
- Trial name
- NCT02515994
- Testing
- senofilcon C, comfilcon A
- Where
- 10 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens Solutions
A Range of Contact Lenses and Care System Combinations
The objective of this study is to compare the short-term clinical response to all combinations of two lens types: fanfilcon A and comfilcon A with two care systems: Hy-Care and Lite.
- Trial name
- NCT03632083
- Testing
- Hy-Care Contact Lens Solution, Lite Contact Lens Solution, fanfilcon A soft contact lens
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- CooperVision, Inc.
Contact Lens Wettability
Effect of FID 114675A on Lens Wettability
The purpose of this study is to evaluate lens wettability of contact lenses when used with an investigational multi-purpose disinfecting solution.
- Trial name
- NCT01342107
- Testing
- FID 114675A multi-purpose disinfecting solution (MPDS), Soft contact lens, Blister pack solution
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Alcon Research
Refractive Error
Effectiveness of a Marketed One-Step Peroxide Lens Care Solution in Symptomatic Contact Lens Wearers
The purpose of this study is to assess improvement of palpebral roughness and associated symptoms with 3 months use of Clear Care®.
- Trial name
- NCT01996709
- Testing
- Hydrogen peroxide-based contact lens solution, Habitual contact lens solution, Habitual contact lenses
- Volunteers
- 142 people
- Sponsor
- Alcon Research
Contact Lens Care
7-Day, Multi-Site Study of an Investigational Multi-Purpose Disinfecting Solution for Contact Lens Wearers
The purpose of this study is to clinically evaluate solution-related corneal staining with an investigational multi-purpose disinfecting solution (MPDS) in hydrogel and silicone hydrogel contact lens wearers.
- Trial name
- NCT00884806
- Testing
- FID 114675A Multi-Purpose Disinfecting Solution (MPDS), Etafilcon A contact lens (ACUVUE® 2™), Senofilcon A contact lens (ACUVUE® OASYS™)
- Volunteers
- 110 people
- Sponsor
- Alcon Research
Myopia
Clinical Evaluation of the Long-Term Effects of Contact Lens Care Systems
The purpose of this study is to compare two marketed contact lens care solutions in regards to comfort and ocular health.
- Trial name
- NCT00813761
- Testing
- O2Optix contact lens, Proclear contact lens, ReNu MultiPlus Multi-Purpose Solution
- Where
- 26 sites in United States, United Kingdom
- Volunteers
- 473 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Astigmatism
Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems
The purpose of this study is to evaluate the lipid uptake, wetting characteristics, and visual performance of AIR OPTIX® AQUA and ACUVUE® OASYS® with HYDRACLEAR® contact lenses when used in conjunction with two contact lens care…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01699750
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE® PUREMOIST® MPDS
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Alcon Research
Refractive Error
Clear Care® Plus vs. PeroxiClear™
The purpose of this study is to evaluate Clear Care® Plus compared to PeroxiClear™ for mean residual peroxide in used lens cases collected at Day 30 after neutralization at recommended storage time.
- Trial name
- NCT02413333
- Testing
- Clear Care Plus contact lens solution, PeroxiClear contact lens solution, Silicone hydrogel contact lenses
- Volunteers
- 133 people
- Sponsor
- Alcon Research
Presbyopia
CLEAR CARE® PLUS for Presbyopic Contact Lens Wearers
The purpose of this study is to evaluate CLEAR CARE® PLUS (CCP) compared to non-HYDRAGLYDE® multi-purpose contact lens solutions in presbyopes currently wearing soft contact lenses and experiencing symptoms of dryness.
- Trial name
- NCT02965833
- Testing
- 3% hydrogen peroxide solution with HydraGlyde® Moisture Matrix, Habitual Multi-Purpose Contact Lens Solution, Habitual Contact Lenses
- Volunteers
- 126 people
- Sponsor
- Alcon, a Novartis Company
Stevens-Johnson Syndrome, Graft Versus Host Disease in Eye
Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease
The goal of this research is to determine if the Tangible Boost system adequately replenishes the Hydra-PEG coating on the surface of a rigid contact lens.
- Conditions
- Stevens-Johnson Syndrome, Graft Versus Host Disease in Eye, Sjogren's Syndrome, Dry Eye
- Trial name
- NCT04313725
- Testing
- Tangible Boost
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Tangible Science
Myopia, Astigmatism
Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Soft Contact Lens Wearers
The purpose of this study is demonstrate substantial equivalence of an investigational contact lens disinfecting solution to a commercially available contact lens solution in silicone hydrogel and soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Hyperopia, Refractive Error
- Trial name
- NCT01912768
- Testing
- FID 120947A contact lens disinfecting solution, renu fresh multi-purpose solution, Soft contact lenses
- Volunteers
- 362 people
- Sponsor
- Alcon Research
Myopia, Hyperopia
One-month Clinical Evaluation of Oté Sensation Multi-Purpose Solution Care System
The purpose of this study is to evaluate the clinical performance of the contact lens care product Oté Sensation in a representative population of soft contact lens wearers.
- Trial name
- NCT03278223
- Testing
- Test solution, Control solution
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- OTE North America
Contact Lens Moisture
Effect of an Investigational Multi-Purpose Solution on Lens Moisture
The purpose of the study is to evaluate the effect of an investigational multi-purpose disinfecting solution (MPDS) compared to a marketed multi-purpose solution on the moisture of silicone hydrogel contact lenses.
- Trial name
- NCT01341990
- Testing
- FID 114675A Multi-Purpose Disinfecting Solution (MPDS), ReNu Fresh Lens Comfort Multi-Purpose Solution (MPS), Silicone Hydrogel Contact Lenses
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Alcon Research
Healthy Contact Lens Wearers
Safety and Efficacy of an Investigational Multi-Purpose Disinfecting Solution
The purpose of this study is to determine if Alcon MPDS is safe and effective for silicone hydrogel and soft hydrogel contact lens wearers.
- Trial name
- NCT01341977
- Testing
- Alcon MPDS, ReNu Fresh MPS
- Where
- United States
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens Wear
Evaluation of Silicone Hydrogel Lens Wettability With Marketed Lens Care Solutions
The purpose of this study is to assess ex vivo wettability of a commonly prescribed silicone hydrogel (SiH) contact lens with three marketed contact lens care solutions.
- Trial name
- SILVER (NCT01252134)
- Testing
- Biotrue multipurpose solution, Sauflon Synergi multipurpose solution, OTE Elements multipurpose solution
- Volunteers
- 22 people
- Sponsor
- Alcon Research