Clinical trials: Contact Dermatitis
Granuloma, Aluminum Allergy
Detection of Aluminium-reactive T-lymphocytes in Patients With Vaccination Granulomas
Vaccines and subcutanoeus immunotherapy vaccines often contains aluminium, and may induce itching granulomas at the injection site. This is usually diagnosed by patch testing.
- Trial name
- NCT06130462
- Testing
- Aluminum, Tetanus toxoid
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Allergy Research Center, Denmark
Chronic Hand Eczema, Chronic Hand Dermatitis
Chronic Hand Eczema - Self-management and Prognosis
Hand eczema is a common disease which often gives a chronic course thus affecting many functions in daily life. The body of evidence related to self-management of chronic hand eczema is poor.
- Trial name
- NCT01482663
- Testing
- Healthy Skin Clinic
- Where
- 2 sites in Denmark
- Volunteers
- 306 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Allergic Contact Dermatitis
Evaluation of EB01 Cream for the Treatment of Chronic Allergic Contact Dermatitis
The purpose of this study is to evaluate the safety and efficacy of EB01 Cream (0.2%, 1.0%, 2.0%) applied twice per day (BID) for the treatment of moderate to severe chronic allergic contact dermatitis (ACD).
- Trial name
- NCT03680131
- Testing
- EB01 Cream 0.2%, EB01 Cream 1.0%, EB01 Cream 2.0%
- Where
- 15 sites in United States, Canada
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Edesa Biotech Inc.
Peristomal Skin Complication
Preliminary Evaluation of CASTLE Barrier Prototype UK
The purpose of this study is to provide preliminary assessment of the safety and performance of a novel barrier formulation (CASTLE) in a small population of subjects with irritated peristomal skin.
- Trial name
- NCT01530087
- Testing
- CASTLE barrier
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- Hollister Incorporated
Acceptance, Social, Sensitivity, Contact
Evaluation of Cutaneous Acceptability and Perceived Effectiveness of a Nasal Spray (Health Care Products)
This is a clinical study for health care product safety assessment. The research is going to conducted with 45 subjects, aged 18 to 70 years, women users of the product category, regardless of color/race, ethnicity, sexual…
- Trial name
- NCT05508230
- Testing
- Hyaluronic Nasal Spray
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Allergic Contact Dermatitis
Clinical Evaluation of Bacitracin
The purpose of this study is to establish a concentration of a bacitracin-patch for diagnosing allergic contact dermatitis.
- Trial name
- NCT00132600
- Testing
- bacitracin (allergen)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mekos Laboratories AS
Contact Dermatitis, Contact Dermatitis Irritant
Testing an Intervention in Irritative Contact Dermatitis
An eczematous reaction is an inflammatory intolerance response of the skin. In acute phase the reaction is characterized by erythema and blistering while in the chronic phase it presents as dryness, itchiness and lichenification.
- Trial name
- NCT06189144
- Testing
- Emollient cream treatment, no treatment
- Where
- Croatia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Allergic Contact Dermatitis
Characterization of Visual Characteristics in Allergic Contact Dermatitis Using the Skincam® Tool
Contact dermatitis (CD) is a common inflammatory skin disease, affecting approximately 15-20% of the general population in industrialized countries and ranking first among occupational diseases in many European countries.
- Trial name
- PatchCam (NCT06351449)
- Testing
- The patch under study is photographed using the SkinCam®
- Volunteers
- 500 people
- Sponsor
- Hospices Civils de Lyon
Contact Dermatitis, Contact Dermatitis Irritant
Molecular Diagnosis of Allergic Contact Dermatitis
Allergic contact dermatitis (ACD) is a common inflammatory skin disease, affecting approximately 15-20% of the general population in industrialized countries and ranking first among occupational diseases in many European…
- Conditions
- Contact Dermatitis, Contact Dermatitis Irritant, Contact Dermatitis, Allergic
- Trial name
- MODAL (NCT06177314)
- Testing
- correlate the molecular signatures of active lesions of contact dermatitis with allergological results
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Allergic Contact Dermatitis
Allergy Skin Patch Artificial Intelligence (AI)
The purpose of this research is to assess human and artificial intelligence performance in grading contact dermatitis reactions in healthy volunteers.
- Trial name
- NCT05339750
- Testing
- AI-based smartphone application, Allergen patch
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diaper Dermatitis
Evaluation of Factors Affecting Diaper Dermatitis
Diaper dermatitis is one of the most common skin problems in infants and children.It is a skin disorder in the perineal , perianal and surrounding area .It frequently occurs also in areas immediately adjacent to the diaper area .
- Trial name
- NCT04294186
- Volunteers
- 50 people
- Sponsor
- Assiut University
Sensitivity, Contact
Sensitization Study of ATx201 in Healthy Volunteers
This is a Phase I, single-site study to evaluate the sensitization potential of topically applied ATx201 GEL, 2% and 4%, along with a placebo control, in healthy human subjects.
- Trial name
- NCT03375957
- Testing
- ATx201
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- UNION therapeutics
Contact Allergic Dermatitis, Adverse Skin Reaction
Aquacel Hypersensitivity Dressing in TJAs
The aim of this multi-surgeon, single institution study is to prospectively evaluate the incidence of allergic contact dermatitis (ACD) following application of AQUACEL Ag, a silver-containing hydrofiber dressing, in total hip…
- Trial name
- NCT06011629
- Testing
- Aquacel dressing
- Where
- United States
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Hypersensitivity Reactions, Allergic Contact Dermatitis
Evaluation of Hypersensitivity Reactions to Silk Fibroin Versus 2-octyl Cyanoacrylate Mesh in Shoulder Surgery
The purpose of this study is to document the incidence of allergic contact dermatitis (ACD) to silk fibroin and 2-octyl cyanoacrylate mesh dressings after open shoulder surgery, to identify differences in clinic utilization for…
- Trial name
- NCT07573202
- Testing
- Silk fibroin (SYLKE), 2-octyl cyanoacrylate mesh (Dermabond PRINEO)
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- The University of Texas Health Science Center, Houston
Skin Barrier Disruption and Recovery
Helichrysum Italicum Extract in Irritant Contact Dermatitis
The goal of this clinical trial is to evaluate the efficacy and safety of a topical cream containing Immortelle (Helichrysum italicum) extract in promoting skin barrier recovery and reducing signs of irritant contact dermatitis…
- Trial name
- NCT07676253
- Testing
- Helichrysum italicum Extract Cream
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Dermatitis
Clinical Investigation on the Performance and Safety of DermoRelizema Ecofoam
The scope of this open label clinical trial is to evaluate and confirm the performance of DermoRelizema ecofoam in the improvement of the dermatitis severity, by alleviating the symptomatology.
- Trial name
- NCT04826471
- Testing
- DermoRelizema ecofoam
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Relife S.r.l.
Allergic Contact Eczema
Assess Itch Behavior in Nickel Sulphate Sensitized Volunteers
Determine the mean time to itch relief from the start of treatment with topic methylprednisolone aceponate.
- Trial name
- NCT01529320
- Testing
- Adventan® (methylprednisolone aceponate 0,1%)
- Where
- Spain
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Fundacion IMIM
Phototoxicity
Evaluation of Potential Phototoxicity Skin Reaction After Use of MC2-01 Cream
This trial is a 4-day, randomized study to determine the phototoxic potential of MC2-01 Cream when topical application to healthy skin is followed by light exposure.
- Trial name
- NCT03892564
- Testing
- MC2-01 Cream, irradiation, MC2-01 Cream, no irradiation, MC2-01 vehicle, irradiation
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- MC2 Therapeutics
Contact Dermatitis
Clinical Evaluation of Lyral® Dose Response Study
The purpose of this study is to determine optimal allergen dose as the lowest concentration eliciting positive reactions in 70-90% of subjects.
- Trial name
- NCT02028182
- Testing
- Lyral®
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Allerderm
Healthy Volunteer
Safety Evaluation of KX01 Ointment 1% in Japanese Healthy Male Subjects
Skin Irritation and Phototoxicity Study of KX01 Ointment 1% in Japanese healthy male subjects
- Trial name
- NCT05245578
- Testing
- KX01 ointment 1%
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- PharmaEssentia