Clinical trials: Constipation, completed
Constipation
Assessment of Whole Gut Transit Time Using the SmartPill Capsule
Our null hypothesis states that the two techniques (Sitzmarks radioopaque markers and SmartPill) are equivalent and is demonstrated if the study population shows a correlation of 0.7 or higher.
- Trial name
- WholeGut (NCT00603707)
- Where
- 8 sites in United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- The SmartPill Corporation
Constipation
Itopride as an Adjuvant for Bowel Preparation in Patients With Chronic Constipation is Effective
Bowel preparation is a major determinant of colonoscopy and colorectal surgery. Polyethylene glycol electrolyte solutions (PEG-E) are the most commonly used laxatives in China.
- Trial name
- NCT01513811
- Testing
- Polyethylene glycol electrolyte solutions, Itopride and Polyethylene glycol electrolyte solutions
- Where
- China
- Volunteers
- 115 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Constipation, Dyspepsia
Study of Yili "Changqing" Pro-ABB Yoghurt in the Improvement of Human Gastrointestinal Tract System
The purpose of this study is to determine whether Yili "Chang Qing" Pro-ABB yoghurt is effective in improving mild constipation and the intestinal micro-ecology environment \& alimentation.
- Conditions
- Constipation, Dyspepsia, Flatulence, Abdominal Pain
- Trial name
- NCT01682798
- Testing
- Yili "Chang Qing" Pro-ABB yoghurt (Formula 1), Yili "Chang Qing" Pro-ABB yoghurt (Formula 2)
- Where
- 2 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Inner Mongolia Yili Industrial Group Co., Ltd
Hemodialysis, Constipation
The Effect of Abdominal Massage on Constipation
This study aimed to determine the effect of abdominal massage on constipation in patients undergoing hemodialysis. The main questions he intends to answer are: H0: Abdominal massage applied to patients undergoing hemodialysis…
- Trial name
- NCT07402785
- Testing
- abdominal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Firat Tukenmez
Gas and Bloating, Diarrhea
Radicle GI Health RDH™: A Study Assessing the Impact of Health and Wellness Products on Gastrointestinal (GI) Health and Related Health Outcomes
A Randomized, Double-Blind, Placebo-Controlled Direct-to-Consumer Study Assessing the Impact of Health and Wellness Products on Gastrointestinal (GI) Health and Related Health Outcomes
- Conditions
- Gas and Bloating, Diarrhea, Constipation
- Trial name
- NCT07230821
- Testing
- GI Health Active Product 1
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Constipation - Functional
Acupuncture for Functional Constipation in Older Adults
Through a scientific and standardized randomized controlled study, we observe the effectiveness and safety of acupuncture in the treatment of functional constipation in the elderly through the method of "nourishing kidney and…
- Trial name
- NCT05496543
- Testing
- acupuncture
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Yin Ping
Constipation, Neoplasms
Constipation in Pediatric Cancer Patients Receiving Vinca Alkaloids or Narcotics
This study will evaluate a questionnaire for measuring constipation in children with cancer. The questionnaire used in this study (Constipation Assessment Scale) reliably predicts the presence and severity of constipation in…
- Trial name
- NCT00032682
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Stress, Constipation
The Effects Of Probiotics On Stress Among Healthy Adults From Umm Al-Qura University At Makkah
The goal of this clinical trial is to study the effects of probiotic supplementation on stress levels and bowel habits in healthy Saudi adults for both males and females.
- Conditions
- Stress, Constipation, Anthropometry, Bowel Disease
- Trial name
- NCT06464484
- Testing
- Probiotics (Lactobacillus rhamnosus GG (ATCC 53103)
- Where
- Saudi Arabia
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Cardiovascular Disease, Constipation
Dose-Response Study of Probiotic Bacteria BB-12 and CRL-431 in Healthy Young Adults
The purpose of the study was to investigate the dose-response effect of increasing doses of Bifidobacterium animalis ssp lactis (BB-12) and Lactobacillus paracasei ssp paracasei (CRL-431) on the immune response, blood lipids, gut…
- Trial name
- NCT00611299
- Testing
- BB-12 and CRL 431
- Where
- Denmark
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Irritable Bowel Syndrome, Digestive System Diseases
Efficacy of a Multi-strain Probiotic in the Treatment of Irritable Bowel Syndrome
The Canadian College of Naturopathic Medicine is conducting a research study on Irritable Bowel Syndrome (IBS), a common condition in North America.
- Conditions
- Irritable Bowel Syndrome, Digestive System Diseases, Colonic Diseases, Functional, Colitis, Mucous
- Trial name
- IBS (NCT01887834)
- Testing
- Kyodophilus multi-strain probiotic capsules
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Irritable Bowel Syndrome With Constipation (IBS-C)
Phase III Study to Evaluate the Efficacy and Safety of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome
The objective of this study is to evaluate the efficacy and safety of ASP0456 in patients with constipation predominant irritable bowel syndrome (IBS-C).
- Trial name
- NCT02316899
- Testing
- linaclotide
- Where
- 61 sites in Japan
- Volunteers
- 500 people
- Sponsor
- Astellas Pharma Inc
Constipation
Sodium Picosulphate vs. Placebo in Functional Constipation
The objective ot the study is to compare the efficacy and safety of 4 weeks treatment with sodium picosulphate drops 10mg to placebo in patients with functional constipation.
- Trial name
- NCT00576810
- Testing
- sodium picosulphate
- Where
- 43 sites in Germany
- Volunteers
- 367 people
- Sponsor
- Boehringer Ingelheim
Chronic Constipation
Study to Evaluate the Effects of RM-131 in Patients With Chronic Constipation
The purpose of this study is to evaluate safety and tolerability as well as the effects of RM-131 on colonic motor and sensory effects in patients with chronic constipation.
- Trial name
- NCT02137642
- Testing
- RM-131
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Motus Therapeutics, Inc.
Constipation, Prolapse, Vaginal
Effect of Preoperative Fiber on Postoperative Bowel Function
Post-operative constipation is one of the most common complaints after pelvic organ prolapse surgery. Psyillum fiber is an FDA-approved, over the counter dietary supplement that is commonly used to treat constipation.
- Trial name
- NCT04882995
- Testing
- Psyillium fiber
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Anorectal Disorder, Fecal Incontinence
Normal Values in Ano-rectal 3D High Resolution Manometry
Ano-rectal manometry is indicative in patients with either fecal incontinence or constipation. Recently anorectal 3D- high resolution manometry has been developed.
- Conditions
- Anorectal Disorder, Fecal Incontinence, Constipation
- Trial name
- NOMAD (NCT01710579)
- Testing
- Anorectal 3D-high resolution manometry, Anorectal radial endosonography (rotative 360° probe), Dynamic anorectal endosonography (sagittal and radial)
- Where
- France
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Constipation
Efficacy and Tolerability of ABB I5 Prebiotic and ABB C22 Postbiotics for the Management of Constipation and Gastrointestinal Well-being: a Pilot Trial
In this study, we aim at assessing the benefits of dietary supplementation with ABB i5 and ABB C24, a combination of the the prebiotic ABB i5 and the postbiotic ABB C22, on the gut microbiota of people with constipation and on…
- Trial name
- ABB i5/ABB C24 (NCT06738433)
- Testing
- ABB i5, ABB C24
- Where
- South Sudan
- Volunteers
- 34 people
- Sponsor
- AB Biotek
Constipation, Fecal Incontinence
Sierra High Definition Ano-Rectal Manometry
Hypotheses: High definition manometry (HDM) is safe and feasible in humans; HDM accurately characterizes anorectal anatomy and function in healthy humans; HDM provides comparable information regarding the structure and function…
- Trial name
- NCT01300884
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Augusta University
Constipation
The Effects of a Probiotic Fermented Milk on Functional Constipation in Adults
The purpose of this study is to determine the effects of daily consumption for 4 weeks of a fermented milk drink containing a live probiotic microorganism, Lactobacillus casei strain Shirota (LcS) compared to a placebo without…
- Trial name
- NCT01161784
- Testing
- Probiotics fermented milk, Nutrient drink
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- IMU University, Malaysia
Chronic Constipation
Effect of Propofol on Internal Anal Sphincter Pressure During ARM
Background and Aim: An anorectal manometry (ARM) is a common test in the evaluation of outlet obstruction in constipation. In children under 6 yo, anesthesia is often used for patient comfort and compliance.
- Trial name
- NCT01793753
- Testing
- Propofol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Constipation
Probiotics for Alleviating Chronic Constipation in Adults
To investigate the clinical effects of probiotics in relieving intestinal motility and chronic constipation through regulating gut microbiota.
- Trial name
- NCT07152795
- Testing
- Probiotic
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.