Clinical trials: Constipation, completed
Irritable Bowel Syndrome, Functional Dyspepsia
The Multi-disciplinary Treatment of Functional Gut Disorders Study
Randomised controlled trial comparing standard outpatient clinic treatment with multi-disciplinary clinic treatment for functional gastrointestinal disorders.
- Conditions
- Irritable Bowel Syndrome, Functional Dyspepsia, Constipation - Functional, Faecal Incontinence
- Trial name
- MANTRA (NCT03078634)
- Testing
- Multi-disciplinary clinic model, Standard outpatient care
- Where
- Australia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- St Vincent's Hospital Melbourne
Irritable Bowel Syndrome With Constipation, Constipation-predominant Irritable Bowel Syndrome
Safety and Efficacy of Non-alcoholic Beverage Based on Kombucha in Patients With Constipations
Single centre, open-label, non-randomized study is planned to proof the concept of safety and efficacy of newly developed specialized food product - non-alcoholic pasteurized beverage based on kombucha, enriched with inulin and…
- Trial name
- Kombucha (NCT05164861)
- Testing
- kombucha-based beverage
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Vasily Isakov
Chronic Idiopathic Constipation
Performance, Efficacy and Safety of Vibrating Capsule in Aiding Constipated Individuals
This is a study intended to evaluate the efficacy and safety of the vibrating capsule versus sham non-vibrating capsule on spontaneous bowel movement, in aiding reliving Constipated Individuals
- Trial name
- NCT02030756
- Testing
- vibrating capsule
- Where
- 18 sites in United States, Israel
- Volunteers
- 144 people
- Sponsor
- Vibrant Ltd.
Irritable Bowel Syndrome With Constipation (IBS-C)
A Study of the Effect of SYN-010 on Subjects With IBS-C
A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multi-Dose Study of the Effect of Two Dosage Strengths of SYN-010 Compared with Placebo on Breath Methane Production in Breath Methane-Positive Subjects with…
- Trial name
- NCT02495623
- Testing
- SYN-010 21 mg, SYN-010 42 mg
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Theriva Biologics, Inc.
Functional Constipation
A Study to Assess Adverse Events and Change in Disease Activity in Pediatric Participants (Age 6 Months to <2 Years) With Functional Constipation Who Are Treated With Linaclotide
Functional constipation (FC) is a common healthcare problem in children of all ages, potentially due to genetic predisposition, inadequate fiber and fluid intake, and immobility.
- Trial name
- NCT05760313
- Testing
- Linaclotide
- Where
- 38 sites in United States, Bulgaria and 5 more
- Volunteers
- 19 people
- Sponsor
- AbbVie
Postoperative Constipation
Prevention of Constipation: Systematic Nursing Interventions to Reduce Postoperative Constipation After Thoracic Surgery
The purpose of the study is to reduce the incidence of postoperative constipation by systematic nurse assessment, interventions and evaluation, in the first month after thoracic surgery.
- Trial name
- NCT00364169
- Testing
- Degree of constipation
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Constipation
Prucalopride in Paediatric Subjects, With Functional Faecal Retention
The purpose of this study is characterize the efficacy, safety, tolerability, and steady-state plasma levels after once-daily oral dosing of prucalopride (R108512) as a solution, 0.01 mg/kg to 0.03 mg/kg, given to paediatric…
- Trial name
- NCT01670669
- Testing
- prucalopride
- Volunteers
- 37 people
- Sponsor
- Movetis
Constipation, Stool
The Effect of Preoperative Abdominal Massage on Postoperative Constipation
The aim of this clinical study is to determine whether preoperative abdominal massage has an effect on the development of postoperative constipation.
- Trial name
- NCT07570004
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Burcu Ozkan
Infections, Stool Flora
Efficacy and Safety of an Infant Formula With Milkfat and Prebiotics
The purpose of this clinical trial is to evaluate the effect of a new infant starter formula with added prebiotics (GOS) and with a fat blend rich in beta-palmitate.
- Conditions
- Infections, Stool Flora, Stool Biochemistry, Constipation
- Trial name
- NCT01603719
- Testing
- new infant formula with prebiotics and beta-palmitate
- Where
- Germany
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Waldkrankenhaus Protestant Hospital, Spandau
Cerebral Palsy, Chronic Constipation
Synbiotic, Prebiotics and Probiotics in Children With Cerebral Palsy and Constipation
Randomized double blind controlled clinical trial. Participants will be enrolled at the New Civil Hospital of Guadalajara "Dr. Juan I. Menchaca" during the period from May 2017 to July 2018, from six to 59 months of either sex.
- Trial name
- NCT03117322
- Testing
- agave inulin, Lactobacillus reuteri DSM 17938, maltodextrin
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Andrea Garcia Contreras
Functional Constipation
Lactobacillus Reuteri DSM 17938 in Functional Constipation
The diffusion of gastrointestinal (GI) chronic diseases is significantly increased during the last century in western countries.
- Trial name
- LRFC (NCT01244945)
- Testing
- L. reuteri DSM 17938
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Chronic Constipation (CC) (Excluding Constipation Due to Organic Diseases), Irritable Bowel Syndrome With Constipation (IBS-C)
Post-marketing Surveillance of Linaclotide Tablet in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation (Excluding Constipation Due to Organic Diseases)
The objective of this study is to evaluate the long-term safety and efficacy of linaclotide in post-marketing use.
- Trial name
- NCT03471728
- Testing
- linaclotide
- Where
- 47 sites in Japan
- Volunteers
- 2,475 people
- Sponsor
- Astellas Pharma Inc
Functional Constipation
The Effect of Probiotics on Functional Constipation in the Elderly
The main scope of the proposed research in the framework is to investigate the effect of probiotic bacteria Lactobacillus acidophilus LA3, Bifidobacterium animalis ssp.
- Trial name
- NCT04506801
- Testing
- Probalans senior
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Katarina Fehir Šola
Gastrointestinal Disorder, Functional, Regurgitation, Gastric
Transition to Infant Formula Feeding on Gastrointestinal Regurgitation (TIGER) Study
To compare the frequency of regurgitation and other digestive outcomes between infants who receive an infant formula based on whole goat milk and an infant formula based on cow milk proteins during the transition period from…
- Conditions
- Gastrointestinal Disorder, Functional, Regurgitation, Gastric, Colic, Infantile, Constipation - Functional
- Trial name
- TIGER (NCT05363553)
- Testing
- Infant formula based on whole goat milk, infant formula based on cow milk proteins
- Where
- Thailand
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Dairy Goat Co-operative (N.Z.) Limited
Constipation
Biofeedback Treatment for Functional Constipation
The purpose of this randomized, controlled trial is to examine how well biofeedback treatment works to improve constipation. The study is comparing two kinds of biofeedback treatment: 1) anorectal-specific biofeedback therapy and…
- Trial name
- NCT00502957
- Testing
- Biofeedback
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Chronic Constipation
Effectiveness and Safety of Probiotic in Regulating Chronic Constipation
To evaluate the effectiveness and safety of the use of probiotics as food supplements in regulating the intestinal habit of subjects with chronic constipation, in comparison with placebo.
- Trial name
- NCT05980988
- Testing
- Probiotic
- Where
- 2 sites in Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Constipation
Evaluation of Long-term Prucalopride Treatment With Chronic Constipation in Subjects Aged ≥ 18 Years
The purpose of this trial is to evaluate the long-term (24 weeks) efficacy of prucalopride versus placebo in subjects aged 18 years and older with chronic constipation.
- Trial name
- SPD555-401 (NCT01424228)
- Testing
- prucalopride
- Where
- 60 sites in Belgium, Czechia and 7 more
- Volunteers
- 364 people
- Sponsor
- Shire
Constipation, Nursing Caries
Nursing Homes on Constipation and General Comfort
The Effect of Reminiscence Therapy on Constipation Applied to Elderly Individuals Staying in a Nursing Home in Giresun Province
- Trial name
- NCT06788392
- Testing
- reminiscence therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Giresun Huzurevi Yaşlı Bakım ve Rehabilitasyon Merkezi
Irritable Bowel Syndrome
Effect of Lactobacillus Plantarum 299v on Symptoms of Irritable Bowel Syndrome
In patients with IBS, will supplementation with a probiotic demonstrate symptomatic efficacy and will the probiotic influence gut microflora and thus improve clinical outcomes, as compared to no intervention.
- Trial name
- NCT01886781
- Testing
- Lactobacillus plantarum 299v, Run in period, Wash - out period
- Where
- South Africa
- Volunteers
- 81 people
- Sponsor
- University of Stellenbosch
Constipation, Surgical Procedure, Unspecified
Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic Surgery
The goal of this clinical trial is to test the use of a laxative before surgery in women having surgery to fix pelvic prolapse that do not have constipation.
- Conditions
- Constipation, Surgical Procedure, Unspecified, Prolapse; Female
- Trial name
- NCT06159777
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University Hospitals Cleveland Medical Center