Clinical trials: Constipation
Constipation
Mechano-physiological Approach to Anorectal Function
We hypothesize that defecatory disorders can be described in mechanical terms which would allow a mechanistic description of disorders which would in turn allow better directed biofeedback mechanisms to treat disorders of…
- Trial name
- NCT00219518
- Testing
- defecography
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Constipation, Childhood Acute Lymphoblastic Leukemia
Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation
To gain a better understanding of the underlying dysmotility in constipation in children, we will use a novel minimal invasive method called 3D Transit.
- Conditions
- Constipation, Childhood Acute Lymphoblastic Leukemia, Neurofibromatosis 1, Chronic Constipation With Overflow
- Trial name
- NCT03981510
- Testing
- 3D-Transit
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Dementia, Cognitive Impairment
Prevalence and Recognition of Geriatric Syndrome in Outpatient Clinic at Srinagarind Hospital
The purpose of this study is to collect the prevalence of geriatric syndrome, which is recognized by an internist, and to compare the data based on the comprehensive geriatric assessment by a geriatrician.
- Conditions
- Dementia, Cognitive Impairment, Depression, Urinary Incontinence
- Trial name
- NCT00892086
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Chronic Constipation
Effect of PEG, Bisacodyl and Prucalopride on Colonic Motility in Healthy Subjects
This study aim was to evaluate the effect of pharmacological treatments normally used to treat functional constipation and in particular PEG, bisacodyl and prucalopride on colonic motility as assessed by high-resolution manometry.
- Trial name
- NCT03279341
- Testing
- polyethylene glycol, Bisacodyl, Prucalopride
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Constipation, Children
Comparison of Anorectal Manometry and 3D Manometry in Diagnosis of Functional Disorders in Children
Pressures measured by manometric solid-state catheters may differ according to the type of the catheter and specific anatomy and physiology of anorectum.
- Conditions
- Constipation, Children, Fecal Incontinence
- Trial name
- NCT02812823
- Testing
- High-resolution anorectal manometry
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Irritable Bowel Syndrome
Prevalence of Intestinal Parasitic Infections in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is common medical disorder and represent a group of diseases of the gastrointestinal tract that is characterized by chronic abdominal pain , bloating , passage of mucus or straining with bowel…
- Trial name
- NCT05830370
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Functional Constipation
Phase 1/2a Trial of YH12852 in Healthy Subjects and Patients With Functional Constipation
A randomized, double-blind/open-label, placebo/active-controlled, single/multiple dose, parallel, phase 1/2a trial to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of YH12852 in healthy subjects and…
- Trial name
- NCT02538367
- Testing
- YH12852 IR 0.05mg, YH12852 IR 0.1mg, YH12852 IR 0.3mg
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
Functional Constipation
An Evaluation of the Effectiveness of a Proprietary Probiotic Blend on Functional Constipation
The primary objective for this study is to monitor the change in patient assessed symptoms of constipation in subjects taking the proprietary probiotic blend compared to those taking the placebo.
- Trial name
- NCT02418507
- Testing
- Proprietary Probiotic Blend
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Endometriosis
The Use of MicroRNAs Dysregulation as Potential Biomarkers for Effective Diagnosis of Endometriosis
OBJECTIVES : 1. To investigate the expression pattern of miRNAs operational in inflammation, angiogenesis, hypoxia, apoptosis and cell proliferation in eutopic and ectopic endometrium of patients with endometriosis and normal…
- Trial name
- ENDMET (NCT06168097)
- Testing
- 100 women undergoing surgery (laparoscopy / laparotomy) with presumed diagnosis of endometriosis, women with intraoperative and / or histopathology findings suggestive of endometriosis
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Healthy, Constipation
Dairy Products to Your Gut and Brain
The goal of this intervention study is to compare the effects of fermented dairy and non-fermented dairy on bowel habits and cognitive performance in healthy women with defecations every other day or less.
- Trial name
- YourGutBrain (NCT06311097)
- Testing
- Fermented dairy, Non-fermented dairy
- Where
- Denmark
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Constipation, Diarrhea
Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population
The purpose of this study is to investigate the effect of a daily supplement consisting of the probiotic bacteria, Lactobacillus reuteri, on the digestive health among persons 65 years and older.
- Conditions
- Constipation, Diarrhea, Indigestion, Reflux
- Trial name
- NCT01837940
- Testing
- Lactobacillus reuteri DSM 17938
- Where
- Sweden
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Constipation, Irritable Bowel Disease
Relationship Between Interoception and Postural Control in Constipation-Predominant Irritable Bowel Syndrome
This cross-sectional, observational, controlled comparative study aims to investigate the relationship between interoception and postural control in individuals with constipation-predominant irritable bowel syndrome (IBS-C) and…
- Trial name
- NCT07870915
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Infantile Colic, Constipation - Functional
Bowel And Bladder Function in Infant Toilet Training
The overall purpose is to assess whether assisted infant toilet training during the first year of life can prevent functional gastrointestinal and urinary tract disorders up to 4 year of age.
- Conditions
- Infantile Colic, Constipation - Functional, Bladder Dysfunction, Toilet Training
- Trial name
- BABITT (NCT04082689)
- Testing
- Assisted Infant Toilet Training
- Where
- 6 sites in Sweden
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
Constipation
Effectiveness of Non-invasive Neuromodulation for Intestinal Transit in Healthy Subjects
Objectives Main objective: Assess the effectiveness of non-invasive neuromodulation treatment (NESA) for the management of constipation in patients without diagnosed pathology in Spain Secondary objectives: Evaluate the…
- Trial name
- NCT06294457
- Testing
- Non-Invasive Neuromodulation NESA
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Gut Health
A Study to Evaluate the Effects of a Butyrate-Polyphenol Formulation on Gut Health and Associated Symptoms
The purpose of the study is to evaluate the efficacy of a butyrate/polyphenol formulation on modulation of the gut microbiome and gastrointestinal symptoms using questionnaires in individuals with self-reported gastrointestinal…
- Trial name
- NCT07371975
- Testing
- Butyrate + Polyphenol Formulation
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Constipation
Oat Milk for Laxation
This study intends to recruit 90-100 constipated participants aged 25-50 years, including an equal number of males and females, from the faculty and logistics staff of Capital Medical University.
- Trial name
- NCT07302542
- Testing
- oat milk
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Constipation
Bowel Function After Minimally Invasive Hysterectomy
Postoperative constipation affects up to a third of women undergoing minimally invasive (MIS) gynecologic surgery and is a major source of anxiety and discomfort.
- Trial name
- NCT04263896
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Constipation
Safety Evaluation of the Vibrating Capsule
The study will assess the safety of the vibrating capsule in healthy volunteers first and than for constipation relief constipated individuals.
- Trial name
- Vibrant (NCT01306448)
- Testing
- Vibrant capsule
- Where
- 3 sites in Israel
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Vibrant Ltd.
Irritable Bowel Syndrome (IBS)
Abdominal Symptom Phenotype Study in Children
Children and adults commonly suffer from recurrent abdominal (stomach) pain. One type is called irritable bowel syndrome (IBS). IBS in adults and children is one of the most common and costly health care problems in the US.
- Trial name
- ASPPNB (NCT01204515)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Colon Disease, Functional Constipation
Non-invasive Assessment of Colonic Motility
The current diagnostic process of colonic motility disorders often takes a long time and involves multiple invasive, painful and/or unnecessary diagnostic procedures.
- Conditions
- Colon Disease, Functional Constipation, Electroenterography, Slow Transit
- Trial name
- non-CoMoti (NCT04624334)
- Testing
- Elektro-Entero-Graphy procedure, EEnG Questionnaire, Gold Standard Questionnaire
- Where
- Netherlands
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center