Clinical trials: Conjunctival Diseases
Allergic Conjunctivitis
A Study of TL-925 for the Treatment of Allergic Conjunctivitis
In this prospective Phase 2, single-center, randomized, double-masked, placebo-controlled study, approximately 70 subjects with allergic conjunctivitis will be randomized 1:1 to receive either TL-925 or placebo as topical…
- Trial name
- NCT06153342
- Testing
- TL-925
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Telios Pharma, Inc.
Pterygium
Safety and Efficacy of Cyclosporine Ophthalmic Emulsion in Patients With Primary Pterygium
This study will evaluate the safety and efficacy of Cyclosporine Ophthalmic Emulsion 0.05% (RESTASIS®) in patients with primary pterygium (abnormal growth on surface of eye).
- Trial name
- NCT01109056
- Testing
- cyclosporine ophthalmic emulsion 0.05%, Vehicle
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 115 people
- Sponsor
- Allergan
Vernal Keratoconjunctivitis
Topical Tacrolimus in Vernal Keratoconjunctivitis
The main aim of this study is to evaluate the efficacy and safety of topical tacrolimus 0.01% eyedrops in patients with vernal keratoconjunctivitis.
- Trial name
- NCT02456025
- Testing
- Topical tacrolimus
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- The Eye Center and The Eye Foundation for Research in Ophthalmology
Dry Eye Disease (DED)
Vizol S DIGI EYE Efficacy and Safety Study in Patients With Dry Eye
The clinical investigation was intended to investigate the efficacy, ocular tolerability and safety of Vizol S DIGI EYE, a new eye drops, solution developed by JADRAN - GALENSKI LABORATORIJ d.d., in patients with moderate to…
- Trial name
- NCT07050446
- Testing
- Vizol S DIGI EYE eye drops, 0,9% saline solution, eye drops
- Where
- 3 sites in Serbia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Jadran Galenski laboratorij d.d.
Ocular Surface Disease
Analysis of Videodermatoscopic Parameters of Ocular, Periocular, Conjunctival and Palpebral Neoformations
ANALYSIS OF VIDEODERMATOSCOPIC PARAMETERS OF OCULAR, PERIOCULAR, CONJUNCTIVAL AND PALPEBRAL NEOFORMATIONS
- Trial name
- NCT06714799
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Allergic Conjunctivitis
China Red Eye Study on Allergic Conjunctivitis
This study is the first multi-center cross-sectional study on the diagnosis and misdiagnosis of allergic conjunctivitis in the ophthalmology clinic in China.
- Trial name
- NCT03812952
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Sun Yat-sen University
Pterygium
A Novel Technique for the Removal of Pterygiums
The aim of this study is to introduce a new surgical technique for the removal of pterygiums that entails the use of bipolar electrocautery to secure the graft, rather than sutures.
- Trial name
- NCT02321150
- Testing
- Cautery, Sutures
- Where
- Barbados
- Volunteers
- 50 people
- Sponsor
- The University of The West Indies
Allergic Conjunctivitis
Study Evaluating the Safety of KetoNaph Ophthalmic Solution in Healthy Volunteers
This study is being conducted to evaluate the safety of KetoNaph ophthalmic solution in healthy adult subjects and in pediatric subjects with a history or family history of ocular allergy.
- Trial name
- NCT01159015
- Testing
- KetoNaph, Vehicle
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Pterygium
Clinical Outcomes of Femtosecond Laser-assisted Pterygium Surgery (FLAPS)
The study will be a pilot interventional case series aiming to treat 30 patients with Femtosecond Laser-assisted Pterygium Surgery (FLAPS). All patients included will undergo FLAPS in one eye.
- Trial name
- FLAPS (NCT02866968)
- Testing
- FLAPS
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore Eye Research Institute
Allergic Conjunctivitis
Study Evaluating the Efficacy and Safety of PRT-2761 for the Treatment of Acute and Chronic Allergic Conjunctivitis
To evaluate the efficacy and safety of two concentrations of PRT-2761 as a topical ophthalmic solution for the treatment of the signs and symptoms of acute and chronic allergic conjunctivitis.
- Trial name
- NCT03320434
- Testing
- PRT-2761 0.5%, PRT-2761 1%, Patanol
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- ORA, Inc.
Allergic Conjunctivitis
A Single-Center Evaluation of the Relative Efficacy of EM-100 Compared to Zaditor® (Ketotifen Fumarate Ophthalmic Solution 0.035%) and Vehicle
A Single-Center study to demonstrate the non-inferiority of EM-100 to Zaditor® in the treatment of ocular itching.
- Trial name
- NCT03489941
- Testing
- EM-100, Zaditor®, Vehicle
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Bausch & Lomb Incorporated
Conjunctivitis, Bacterial
Assessment of the Effects and Tolerability of RD03/2016 for the Treatment of Bacterial Conjunctivitis in Adults
This is a phase II, randomized, parallel-group, blinded-assessor, multicentre study to assess the non-inferiority of RD03/2016 eye drops vs.
- Trial name
- MIRAKLE (NCT06616922)
- Testing
- RD03/2016 eye drops, Levofloxacin 0.5% eye drops solution (Oftaquix®)
- Where
- 41 sites in Germany, Italy and 2 more
- Volunteers
- 252 people
- Sponsor
- NTC srl
Dry Eye Syndrome, Tear Film Insufficiency
Corneal Tear Film Imaging of the Cornea Before and After Restasis Therapy
Dry Eye Syndrome (DES) is a disease affects the production and stability of the tear film, leading to vision disturbances and a major decrease in quality of life.
- Trial name
- NCT03403023
- Testing
- Tear Film Imager, Restasis
- Volunteers
- 40 people
- Sponsor
- Meir Medical Center
Pterygium
Bevacizumab for Primary Pterygium Treatment
The aim of this study was to investigate the efficacy and safety of subconjunctival bevacizumab application as an adjuvant therapy for primary pterygium.
- Trial name
- NCT01686529
- Testing
- Autoconjunctival grafting, Subconjuntival bevacizumab injection
- Where
- Mexico
- Volunteers
- 49 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Blepharitis, Conjunctivitis
Safety/Efficacy of Antibiotic Steroid Combination in Treatment of Blepharitis and/or Keratitis and/or Conjunctivitis
Safety and efficacy of antibiotic steroid combination compared with individual administration in the treatment of bacterial ocular inflammation and infection (blepharitis and/or keratitis and/or conjunctivitis).
- Conditions
- Blepharitis, Conjunctivitis, Keratitis
- Trial name
- BRA-07-02 (NCT00732446)
- Testing
- Moxifloxacin and Dexamethasone combined, Moxifloxacin, Dexamethasone
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of São Paulo
Dry Eye, Acupuncture
Medical vs Acupuncture for Dry Eye
This randomized clinical trial was designed to evaluate the effectiveness of acupuncture combined with artificial tears compared to artificial tears alone in patients with moderate dry eye disease.
- Trial name
- ADET (NCT07185854)
- Testing
- Artificial tears, Traditional Chinese Medicine Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Nadide Koca
Allergic Rhinitis, Asthma
The Effect of Pollen Season on Subcutaneous Allergen Immunotherapy Reactions
Subcutaneous allergen immunotherapy (SCIT) is a widely used and effective treatment modality for allergic rhinoconjunctivitis and asthma.
- Conditions
- Allergic Rhinitis, Asthma, Allergic Conjunctivitis
- Trial name
- SCIT (NCT01878929)
- Testing
- Allergen(Tree, Grass, Weeds)
- Where
- United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Bacterial Conjunctivitis
Safety and Efficacy of AL-15469A 0.5% / AL-6515 0.3% Ophthalmic Suspension for Treatment of Bacterial Conjunctivitis
To assess safety and efficacy of AL-15469A 0.5% /AL-6515 0.3% Ophthalmic Suspension for treatment of bacterial conjunctivitis
- Trial name
- NCT01238783
- Testing
- AL-15469A 0.5% and AL-6515 0.3% Ophthalmic Suspension, AL-15469A 0.5%, AL-6515 0.3%
- Sponsor
- Alcon Research
COVID, Conjunctivitis
A Study to Assess the Virus RNA, and miRNA Levels Related to Viral Infection, and Inflammatory Response in Tears of Patients Affected by COVID-19 Disease
The aim of this study is to assess the virus RNA, and miRNA levels related to viral infection, and inflammatory response in tears of hospitalized patients with a diagnosis of COVID-19 with and without conjunctivitis and to…
- Trial name
- NCT04346160
- Testing
- Schirmer Test I
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Vernal Keratoconjunctivitis
Topical Immuonosuppressant Drugs in Spring Catarrh
Spring catarrh is a prevalent type of conjunctival allergic disorder in temperate countries. Topical steroids are the cornerstone management of spring catarrh beside other anti allergic drugs.
- Trial name
- NCT04705584
- Testing
- Prednisolone (as Acetate), CycloSPORINE Ophthalmic Suspension, LTacrolimus Topical
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Assiut University