Clinical trials: Conduction Disorder
Ventricular Tachycardia
Magnetic Stimulation to Treat VT Storm
Ventricular Tachycardia storm is a medical emergency characterized by three or more episodes of ventricular arrhythmia within 24 hours and associated with a significantly increased mortality and massive health resource…
- Trial name
- STAR-VT (NCT04043312)
- Testing
- Magstim SuperRapid
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Pennsylvania
Sick Sinus Node Syndrome
Model 20105 Lead Study
The purpose of this study is to evaluate the implant procedure and feasibility of a new lead developed to pace and sense the left chambers of the heart.
- Trial name
- NCT02301429
- Testing
- Model 20105
- Where
- 4 sites in Canada, Netherlands and 2 more
- Volunteers
- 16 people
- Sponsor
- Medtronic BRC
Long Qt Syndrome 1-2, Sudden Cardiac Death
Exploring Mechanisms and Morphology of QT Interval Prolongation
The projects will try and optimise the risk stratification for patients with Long QT syndrome by investigating how the exposure of physical and acoustic stress will affect the QT-dynamics and if beta blockers protect against…
- Trial name
- TriQarr (NCT03291145)
- Testing
- Beta Blockers, Spironolactone
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Brugada Syndrome (BrS), Ventricular Arrhythmia
Prospective Multicentre Observational Registry of Peri-procedural Anaesthesia, Sedation and Related Medication Exposure in Patients With Brugada Syndrome
The goal of this observational study is to evaluate the perioperative risk of malignant ventricular arrhythmias in adult patients diagnosed with Brugada Syndrome undergoing anaesthetic procedures.
- Conditions
- Brugada Syndrome (BrS), Ventricular Arrhythmia, Anesthesia, Sedation
- Trial name
- PROSP_BRUGANAE (NCT07655102)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Clinic of Barcelona
Ventricular Tachycardia, Ventricular Fibrillation
OPERA: French Observational Study on Patients Implanted With a Guidant PRIZM or Vitality Defibrillator
This study evaluates the date of the first appropriate and/or inappropriate therapy in patients implanted with a Guidant PRIZM or VITALITY defibrillator and is evaluating eventual predictive risk factors for…
- Trial name
- NCT00180375
- Testing
- Prizm, Vitality, Renewal
- Where
- 33 sites in France
- Volunteers
- 636 people
- Sponsor
- Boston Scientific Corporation
Acute Myocardial Infarction, Ventricular Tachycardia
Acute Cardiovascular Events Triggered by COVID-19-Related Stress
The current COVID19 pandemic has afflicted almost the whole globe. The stress related to the pandemic, not the direct virus-related injury, can be potentially associated with acute cardiovascular events due to a large list of…
- Conditions
- Acute Myocardial Infarction, Ventricular Tachycardia, Sudden Cardiac Death, Stroke, Acute
- Trial name
- JoCORE (NCT04368637)
- Where
- 5 sites in Jordan
- Volunteers
- 50 people
- Sponsor
- Jordan Collaborating Cardiology Group
Blood Pressure
Long-term Atrial Pacing and Central Blood Pressure
This is a randomized controlled single-centre clinical trial with a cross-over design to compare non-invasively evaluated central blood pressure and related parametres in sick sinus syndrome patients with hypertension who are…
- Trial name
- NCT04309175
- Testing
- base rate programming of a permanent cardiac pacemaker
- Volunteers
- 58 people
- Sponsor
- Tartu University Hospital
Ventricular Tachycardia
Multimodality Assessment of Ventricular Scar Arrhythmogenicity.
We aim to improve our understanding of a life-threatening heart rhythm disorder known as ventricular tachycardia (VT). This is a disorder which originates from the lower chamber of the heart and frequently is associated with…
- Trial name
- NCT04632394
- Testing
- Generation of computational model from cardiac MRI., VT ablation
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- St George's, University of London
Heart Disease Structural Disorder, Ventricular Tachycardia
Catheter Ablation Versus Anti-arrhythmic Drugs for Ventricular Tachycardia
Sudden cardiac death (SCD) due to recurrent ventricular tachycardia (VT) is an important clinical sequela in patients with structural heart disease.
- Conditions
- Heart Disease Structural Disorder, Ventricular Tachycardia, Cardiomyopathy, Dilated, Sarcoidosis
- Trial name
- CAAD-VT (NCT05524077)
- Testing
- Ablation, Anti-arrhythmic Drugs (AADs)
- Where
- 9 sites in Australia
- Volunteers
- 162 people
- Sponsor
- Western Sydney Local Health District
Severe Aortic Valve Stenosis
MYLEAD Spanish Prospective Registry
Investigator-initiated, prospective, multicentre registry, whose objectives are: 1/ to evaluate the incidence of conduction defects and the need of pacemaker implantation post-procedure, at discharge, at 30 days and at 1 year…
- Trial name
- MYLEAD (NCT06917066)
- Testing
- TAVR
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Tachycardia, Ventricular
Saline-Enhanced Radiofrequency (SERF) Catheter Ablation for the Treatment of Ventricular Tachycardia
The purpose of this study is to demonstrate the technical feasibility of the SERF Catheter and SERF Cardiac Ablation System to eliminate or control ventricular tachycardia (VT)
- Trial name
- SERF-VT (NCT02994446)
- Testing
- Saline-Enhanced Radiofrequency Catheter and Ablation System
- Where
- 3 sites in Canada
- Volunteers
- 25 people
- Sponsor
- Thermedical, Inc.
Ventricular Tachycardia, Ischemic Cardiomyopathy
Catheter Ablation for Nonsustained Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy
Despite established implantable cardioverter-defibrillator (ICD) therapy and catheter ablation for sustained ventricular tachycardia (VT) in patients with ischemic heart disease (IHD) and reduced left ventricular ejection…
- Conditions
- Ventricular Tachycardia, Ischemic Cardiomyopathy, Reduced LVEF
- Trial name
- nsVT (NCT03147027)
- Testing
- VT ablation, medication
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Tachycardia, Ventricular Arrythmia
ExtraVascular Implantable Cardiac Defibrillator Continued Access Study
This study is designed to provide continued access to the Extravascular Implantable Cardioverter Defibrillator (EV ICD) System.
- Trial name
- EV ICD CA (NCT05049720)
- Testing
- Defibrillation using the Extravascular ICD
- Sponsor
- Medtronic
Pacemaker Implantation, TAVI
STIMTAVI : Evolution of Atrioventricular Conduction Disorders After TAVI
The investigators propose to carry out an observational study of patients implanted with a pacemaker using AAI SafeR® mode after a TAVI procedure.
- Trial name
- STIMTAVI (NCT03338582)
- Volunteers
- 275 people
- Sponsor
- Association de Recherche en Cardiologie des Alpes
Type 1 Diabetes Mellitus
Nerve Conduction Velocity in Diabetic Children
The investigators intend to study children and adolescents from 8 to 18 years suffering from diabetes mellitus type 1 for more than one year.
- Trial name
- NCT01017718
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Landeskrankenhaus Feldkirch
Tachycardia, Ventricular
PAtient NOtifier Feature for Reduction of Anxiety
This study is intended to look at the effect of the SJM vibrating Patient Notifier™ system, which will warn the patient of possible failures of the implanted system, on reducing patient device related anxiety
- Trial name
- Panoramic (NCT00559559)
- Testing
- ICD implant + Patient Notifier turned OFF, ICD Implant + Patient Notifier turned ON
- Where
- Switzerland
- Volunteers
- 362 people
- Sponsor
- Abbott Medical Devices
Supraventricular Tachycardia
Troponin Leaks in Emergency Department Patients Presenting With Supraventricular Tachycardia (SVT)
The goal of this study is twofold. First the investigators would like to determine the trajectory of troponin leaks; if it can be shown that the participants who have only minimal elevations of their repeat troponin universally…
- Trial name
- NCT02810561
- Testing
- No Intervention
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Corewell Health South
Paroxysmal Supraventricular Tachycardia
Safety Study of Intranasal Etripamil for the Termination of Spontaneous Episodes of Paroxysmal Supraventricular Tachycardia (PSVT). NODE-302
The primary objective of this study is to evaluate the safety of etripamil nasal spray (NS) 70 mg when self-administered by patients with an episode of Paroxysmal Supraventricular Tachycardia in an outpatient setting (i.e.…
- Trial name
- NCT03635996
- Testing
- Etripamil NS 70 mg, Aptar Pharma Nasal Spray Bidose System
- Where
- 34 sites in United States, Canada
- Volunteers
- 169 people
- Sponsor
- Milestone Pharmaceuticals Inc.
Cardiac Death, Cardiac Death, Sudden
Longitudinal Evaluation of Active-Duty Personnel with Accessory Pathways (LEAD-AP)
The investigators propose a secondary chart review using EMR data to identify risk factors for sudden cardiac death in active-duty members diagnosed with an accessory pathway between the ages of 18-40.
- Conditions
- Cardiac Death, Cardiac Death, Sudden, Wolf Parkinson White Syndrome
- Trial name
- LEAD-AP (NCT06798961)
- Testing
- Ablation, Standard of care without ablation
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- United States Naval Medical Center, San Diego
Tachyarrhythmias, Atrial Fibrillation
OptiSense™ Performance in Detecting Atrial Episodes
The SENSE-AF study aims to determine the performance of the OptiSense lead in sensing fine episodes of Atrial Tachyarrhythmia/Atrial Fibrillation (AT/AF) and rejecting Far-Field R Wave (FFRW).
- Trial name
- SENSE-AF (NCT00870324)
- Testing
- OptiSense Lead, Tendril Lead
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Abbott Medical Devices