Clinical trials: Con
Retinitis Pigmentosa, Cone Dystrophy
Phenotype Correlates Genotype of Inherited Retina Dystrophies, Retinitis Pigmentosa, Con>Rod Dystrophies.
Patients with retina dystrophies (retinitis pigmentosa, cone>rods dystrophies, Usher and syndromic) will be correlated with genotype and validate inheritance mode by segregation analysis.
- Conditions
- Retinitis Pigmentosa, Cone Dystrophy, Usher Syndromes, Retina; Dystrophy
- Trial name
- NCT03990727
- Testing
- Retina Analysis-mosaic, Autofluorescence, OCT- 1 micra
- Where
- Mexico
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- MejoraVisionMD
Cardiovascular Diseases
Drug Eluting Balloon Efficacy for Small Coronary Vessel Disease Treatment
This is a prospective, multicentre, randomized clinical study of consecutive patients with coronary artery disease in vessels with diameter ≤2.75 mm.
- Trial name
- PICCOLETO II (NCT03899818)
- Testing
- drug-eluting balloon, drug-eluting stent
- Volunteers
- 240 people
- Sponsor
- Fatebenefratelli and Ophthalmic Hospital
COVID-19
Efficacy, Safety and Immunogenicity of Inactivated SARS-CoV-2 Vaccines (Vero Cell) to Prevent COVID-19 in Healthy Adult Population In Peru Healthy Adult Population In Peru
This is a multicenter, randomized, double blind, parallel placebo controlled, phase 3 clinical trial to evaluate the protective efficacy, safety and immunogenicity of inactivated SARS-CoV-2 vaccines in healthy population 18 years…
- Trial name
- Covid-Peru (NCT04612972)
- Where
- Peru
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Genitourinary Syndrome of Menopause
Combination of the Vaginal Laser With a Moisturizing and Repairing Niosomal Gel in the Treatment of Genitourinary Syndrome in Oncology Patients
Vaginal laser together with the use of moisturizing and repairing gels could be an effective therapy for the treatment of genitourinary syndrome in women with a history of neoplasia in whom the use of estrogens is not…
- Trial name
- NCT06508788
- Testing
- CO2 laser
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital Universitari de Bellvitge
Carcinoma, Non-Small-Cell Lung, Positron-Emission Tomography
Correlation of Metabolic Imaging With Immune Markers in NSCLC Candidate to Immunotherapy.
The purpose of the present study is to prospectively investigate the correlation between the metabolic parameters on FDG-PET before and during immunotherapy treatment with the immune infiltrate and other tissue or circulating…
- Conditions
- Carcinoma, Non-Small-Cell Lung, Positron-Emission Tomography, Immunotherapy
- Trial name
- NCT03563482
- Testing
- PET scan
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Istituto Clinico Humanitas
COVID-19
Comparison of Two Different Doses of Bemiparin in COVID-19
Patients requiring hospitalization due to COVID-19 pneumonia (non-severe) will be randomized to standard prophylactic doses or full therapeutic dose of bemiparin (a LMWH) for 10 days.
- Trial name
- BEMICOP (NCT04604327)
- Testing
- Bemiparin sodium
- Where
- 12 sites in Spain
- Volunteers
- 164 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Infant Development
Effect of a Mix of Dairy Lipids and Plant Oils in Infant Formula on Omega-3 Fatty Acid in Red Blood Cells
The objective of this study is to determine whether the use of a mix of dairy lipids and plant oils in infant formula can increase the sum of omega-3 fatty acids levels in membrane phospholipids of red blood cells (RBC) in 4…
- Trial name
- REBECA (NCT01611649)
- Testing
- Formula containing dairy lipids and plant oils, Formula containing plant oils, Formula containing dairy lipids and plant oils, DHA+ARA
- Where
- Italy
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Lactalis
Post-COVID19, Parkinson Disease
At Home REhabilitation and Monitoring of People in poST-covid Condition Through ARc-inTellicare Platform (RESTART/RICOMINCIARE)
The RESTART/RICOMINCIARE study is a pilot single-center, not controlled prospective, pre-post intervention study aimed at verifying feasibility and safety of a device-supported home rehabilitation for people suffering from mild…
- Trial name
- RICOMINCIARE (NCT05074771)
- Testing
- ARC intellicare
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Camlin Ltd
Apnea (Central and Obstructive)
MEntA Program Based on Motivational Interview to Improve Adherence to Treatment of Obstructive Sleep Apnea With Continuous Positive Airway Pressure (CPAP)
A randomized, controlled, single-centre trial design was performed. The interventions were standard of care vs MEntA Program based on motivational interview for adherence.
- Trial name
- MEntA Program (NCT07258264)
- Testing
- Motivational Interviewing (MI), Competency-based learning
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Air Liquide Healthcare Spain
AML (Acute Myelogenous Leukemia
Combination of HMA and Venetoclax With Posaconazole in Patients With Acute Myeloid Leukemia: A Study of Plasma Concentrations
Acute Myeloid Leukemia requires intensive chemotherapy treatment, usually followed by an allogeneic bone marrow transplant to reduce the risk of relapse.
- Trial name
- NCT07254611
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Papilloma Viral Infection, CIN1
Evaluation Of The Efficacy Of The Combination Of GLIZIGEN® Oral Solution 1/Day And Vaginal Gel 1/Night For 2 Months In Patients With Cervical Intraepithelial Neoplasia Grade 1 (LSIL/CIN-1) Caused By High-Risk Human Papillomavirus (HPV-AR)
HPV infection can lead to cancer, especially when precancerous lesions have developed and high-risk HPV is present. Glizigen is an oral and intravaginal treatment based on activated glycyrrhizinic acid that has shown potential…
- Conditions
- Papilloma Viral Infection, CIN1, LSIL, Low Grade Squamous Intraepithelial Lesion
- Trial name
- NCT05916911
- Testing
- Glizigen
- Where
- 4 sites in Spain
- Volunteers
- 120 people
- Sponsor
- Catalysis SL
Anorexia Nervosa
Virtual Reality and Autobiographical Recall in Anorexia Nervosa: a Preliminary Study
Clinical trial in patients with Anorexia Nervosa using body-swapping technique e Virtual Reality Body Size estimation tasks and Autobiographic Recall on sympton remission (EDI-3; EDE-Q), body satisfaction and perception
- Trial name
- VIREC (NCT05801016)
- Testing
- Emerging Technologies and Training in Neurosciences
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Auxologico Italiano
Heart Failure
Artificial Voice Analysis and Telemonitoring for Heart Failure. A Feasibility Study
Heart failure is a serious condition and a major reason why older adults are admitted to the hospital. Even after going home, many patients struggle to get the follow-up care they need, leading to high rates of return to the…
- Trial name
- AVATAR-HF (NCT07664748)
- Testing
- AVATAR-SC, Levosimendan
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Niguarda Hospital
Hodgkin or Non-Hodgkin Lymphoma
PAX5-NEGATIVE HODGKIN-LIKE LYMPHOMAS: A DIAGNOSTIC CHALLANGE
Hodgkin lymphoma (HL) is a lymphoma that arises from peripheral B lymphocytes. However, the neoplastic cells, Hodgkin cells and Reed-Sternberg cells, typically lack most B-cell markers, usually preserving the expression of the…
- Trial name
- HL PAX5- 2025 (NCT07313943)
- Where
- 2 sites in Germany, Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Health, Obesity Type 2 Diabetes Mellitus
Safety and Tolerability Evaluationof Phascolarcobacterium Faecium
The goal of this interventional study is to assess the safety and tolerability of the daily administratrion of bacterium Phascolarctobacterium faecium in healthy adults with normal weight, and in individuals with overweight and…
- Conditions
- Health, Obesity Type 2 Diabetes Mellitus, Obesity & Overweight
- Trial name
- NCT07285317
- Testing
- Bacterium P. faecium
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Spanish National Research Council
HIV Infections
Analysis of Changes in Adipose Tissue of Patients With Lipoatrophy HIV Infection Treated With Nucleoside Thymidine, After Switching to Monotherapy With Lopinavir / Ritonavir
The objective is to analyse the changes in the adipose tissue hystological features and the adipogenesis gene expression and related to inflammation after 48 and 96 weeks after the change from AZT+3TC+ABC (Trizivir®) to a…
- Trial name
- BIOKAL (NCT01031849)
- Testing
- Kaletra
- Where
- 2 sites in Spain
- Volunteers
- 7 people
- Sponsor
- Ines Perez
Cleft Lip and Palate, Growth and Development
Efficacy of Maxillo-facial Treatment on Cleft Lip and Palate Patients Faces: Aesthetic Considerations
The aim of the study is to analyze the esthetic outcome of the first surgical repair of cleft lip and palate (CLP) patients. The aim of the study is to identify differences in the aesthetic evaluation of full-face and nasolabial…
- Conditions
- Cleft Lip and Palate, Growth and Development, Cicatrix, Randomized Controlled Trial
- Trial name
- NCT03395015
- Testing
- VAS scale (from 1 to 10) esthetic assessment of facial 3-D images
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Emotional Regulation
Strengthening Emotional Regulation: a Group Intervention With Adolescents
The goal of this clinical trial is to determine the initial efficacy of an emotional regulation skills training (ERST) intervention program in a group of adolescents presenting mild symptoms affecting their ability to regulate…
- Trial name
- NCT06878521
- Testing
- Emotional Regulation Skills
- Where
- Chile
- Volunteers
- 69 people
- Sponsor
- Lorena Wenger Amengual
Stroke, Gait Disorders, Neurologic
Technological Balance and Gait Rehabilitation in Patients With Stroke Sequelae: Functional, Motor and Cognitive Outcomes
Stroke represents the leading cause of disability worldwide, with a significant impact on an individual, family, and economic impact.
- Conditions
- Stroke, Gait Disorders, Neurologic, Balance
- Trial name
- ROAR-S (NCT05280587)
- Testing
- Technological Rehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Proprioception, Visual Perception
Study of the Effect of Proprioceptive Stimuli in the Stomatognathic Area on Visual Perception, With and Without Sound
The goal of this observational study is to investigate how oral proprioceptive stimuli affect visual perception and auditory-visual integration in healthy young adults.
- Conditions
- Proprioception, Visual Perception, Multisensory, Stomatognathic System
- Trial name
- NCT07051460
- Testing
- Baseline Condition (No Stimuli), Auditory Stimulation only, Auditory and Oral Proprioceptive Stimulation (OPS)
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Sophie Román Richon