Clinical trials: Con
Dyslipidemias
Nicotinic Acid Composition of HDL and Arterial Endothelium Function in Premature Coronary Heart Disease and High HDL
Patients with premature ischemic heart disease (PIHD) and elevated levels of HDL-C present an altered composition of high-density lipoproteins (HDL) which is associated with a loss of their anti-atherogenic effects and of their…
- Trial name
- 11MSP011 (NCT01450410)
- Testing
- Nicotinic acid
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Xavier Pinto Sala
Palliative Care
Apoyo Con Carino: Patient Navigation for Palliative Care for Non-Cancer Illness
Palliative care is a priority area of focus for the National Institute of Nursing Research. Despite the evidence-based benefits of palliative care, access remains limited, especially in poor urban and rural settings.
- Trial name
- NCT03181750
- Testing
- Patient Navigator Intervention Group
- Where
- 6 sites in United States
- Volunteers
- 299 people
- Sponsor
- University of Colorado, Denver
Cancer
Apoyo Con Carino: Patient Navigation for Palliative Care
Palliative care is a priority area of focus for health care in an aging population experiencing burdens of chronic illness. Despite the evidence-based benefits of palliative care, access remains limited, especially in poor urban…
- Trial name
- NCT01695382
- Testing
- Navigation
- Where
- 5 sites in United States
- Volunteers
- 223 people
- Sponsor
- University of Colorado, Denver
Sensory Impairments, Cognitive Impairment
Development of an Ensemble Learning-based, Multi-dimensional Sensory Impairment Score to Predict Cognitive Impairment in an Elderly Cohort of Southern Italy
There is now strong scientific literature showing a relationship between sensory loss and cognitive performance and between sensory loss and incident dementia.
- Conditions
- Sensory Impairments, Cognitive Impairment, Artificial Intelligence
- Trial name
- DEMETRA (NCT06783010)
- Volunteers
- 30 people
- Sponsor
- Azienda Sanitaria Locale Bari
Epilepsy
Efficacy Study of a Neuropsychological Rehabilitation Intervention for Children With Non-symptomatic Epilepsy
Patients with non-symptomatic epilepsy, even in the presence of a normative cognitive functioning, present different levels of neuropsychological weaknesses, especially in executive functions and social competences.
- Trial name
- NCT04292093
- Testing
- Home rehabilitation training, Home control activity
- Volunteers
- 48 people
- Sponsor
- IRCCS Eugenio Medea
Shoulder Disease
Catheter Over Needle (CON) vs Catheter Through Needle (CTN).
This is a randomized clinical trial with the objective of comparing the time of insertion of two types of perineural catheters in shoulder surgery.
- Trial name
- CONvsCTN (NCT05960799)
- Testing
- CON - Contiplex C™ (CC), CTN - Contiplex
- Where
- Chile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Stroke, Gait Disorders, Neurologic
Technological Balance and Gait Rehabilitation in Patients With Stroke Sequelae: Functional, Motor and Cognitive Outcomes
Stroke represents the leading cause of disability worldwide, with a significant impact on an individual, family, and economic impact.
- Conditions
- Stroke, Gait Disorders, Neurologic, Balance
- Trial name
- ROAR-S (NCT05280587)
- Testing
- Technological Rehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Advanced Non-small Cell Lung Cancer (NSCLC)
Impact of Liquid Biopsy on the Therapeutic Pathway for Lung Cancer: Advancing the Molecular Characterization of Patients With Advanced Lung Adenocarcinoma by Integrating Liquid Biopsy Into the Early Stages of the Diagnostic and Therapeutic Pathway
This multicenter pilot observational study aims to assess the feasibility of introducing liquid biopsy at an early stage of the diagnostic pathway for patients with suspected advanced non-small cell lung cancer (NSCLC).
- Trial name
- INNOVA-LUNG (NCT07649629)
- Testing
- Plasma-based liquid biopsy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Regina Elena Cancer Institute
Pneumonia
Lung Ultrasound in Pediatric CAP
Community-acquired Pneumonia (CAP) represents the single largest cause of death and morbidity in children worldwide (1). Respiratory viruses are the most common cause of CAP in preschool children, followed by bacteria.
- Trial name
- ULTRASONIC-CAP (NCT05741203)
- Testing
- lung ultrasound
- Volunteers
- 1,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Aortic Aneurysm, Iliac Aneurysm
Safety and Efficacy of the Gore® Excluder® Iliac Branch Platform and Analysis of Its Behavior in Combination With the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis (IBERVIX)
Aorto-iliac aneurysms with involvement of the iliac bifurcation or hypogastric artery aneurysms constitute only 20% of all aneurysmal pathology of the abdominal aorta.
- Trial name
- IBERVIX (NCT04356313)
- Testing
- GORE® EXCLUDER® Iliac Branch Endoprosthesis
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Asociacion para el Estudio de la Enfermedades Vasculares de Galicia
Retinitis Pigmentosa, Cone Dystrophy
Phenotype Correlates Genotype of Inherited Retina Dystrophies, Retinitis Pigmentosa, Con>Rod Dystrophies.
Patients with retina dystrophies (retinitis pigmentosa, cone>rods dystrophies, Usher and syndromic) will be correlated with genotype and validate inheritance mode by segregation analysis.
- Conditions
- Retinitis Pigmentosa, Cone Dystrophy, Usher Syndromes, Retina; Dystrophy
- Trial name
- NCT03990727
- Testing
- Retina Analysis-mosaic, Autofluorescence, OCT- 1 micra
- Where
- Mexico
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- MejoraVisionMD
Type 1 Diabetes Mellitus
Characterization of Type 1 Diabetes Subgroup: An Artificial Intelligence Analysis of Clinical and Glucometric Features
The goal of this observational study is to characterize different subgroups among patients with type 1 diabetes. The main research question is: Are there distinct subtypes among people with type 1 diabetes? Participants will be…
- Trial name
- T1DC (NCT07461805)
- Where
- Spain
- Volunteers
- 800 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Rectal Cancer
Xeloda and Bevacizumab to Treat Rectal Cancer
The project objective is to evaluate the efficacy of the neoadjuvant treatment with bevacizumab, capecitabine and radiotherapy, in patients with rectal adenocarcinoma resectable locally advanced (stage T3 or T4), with or without…
- Trial name
- xeberecto (NCT00847119)
- Testing
- Bevacizumab, capecitabine (Xeloda), Rectal Radiotherapy
- Where
- Spain
- Volunteers
- 43 people
- Sponsor
- Institut Català d'Oncologia
Respiratory Distress Syndrome, Newborn
NIPPV vs.nCPAP During LISA Procedure
The goal of this randomized controlled study is to compare the efficacy of using NIPPV versus NCPAP during the LISA procedure in very preterm infants.
- Trial name
- NIPAL (NCT05796128)
- Testing
- Nasal Intermittent Positive Pressure Ventilation (NIPPV), Nasal continuous positive airway pressure (NCPAP)
- Where
- Italy
- Volunteers
- 202 people
- Sponsor
- University of Florence
Proprioception, Visual Perception
Study of the Effect of Proprioceptive Stimuli in the Stomatognathic Area on Visual Perception, With and Without Sound
The goal of this observational study is to investigate how oral proprioceptive stimuli affect visual perception and auditory-visual integration in healthy young adults.
- Conditions
- Proprioception, Visual Perception, Multisensory, Stomatognathic System
- Trial name
- NCT07051460
- Testing
- Baseline Condition (No Stimuli), Auditory Stimulation only, Auditory and Oral Proprioceptive Stimulation (OPS)
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Sophie Román Richon
Obesity & Overweight
Precision Lifestyle Intervention and Anthropometric, Nutritional, and Metabolic Health Outcomes
This clinical trial aims to recruit a core cohort of adults with normal weight, overweight, and obesity, but without other metabolic alterations, to undergo a six-month nutritional intervention.
- Trial name
- MAR-GEN (NCT07450066)
- Testing
- Diet
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Headache (Migraine), Migraine
Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification
Patients will be asked to visit the study center 2 times, the first time for clinical assessment and a second time for sample collection. Healthy controls will only be asked to visit the study center for sample collection.
- Conditions
- Headache (Migraine), Migraine, Migraine Headache, Migraine with Aura
- Trial name
- FAST (NCT06674772)
- Testing
- Saliva test
- Where
- Spain
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Occupational Health, Resilience
Design of an Intervention to Equip Middle Managers and Managers in Healthcare Institutions With Tools to Increase the Resilience of Their Teams
The main objective of this preparatory action (experimental study without control group, before and after measurements) is to develop and test the feasibility of the e-Resilience tool in a relevant environment (TRL6).
- Conditions
- Occupational Health, Resilience, Job Stress, Well-being at Work
- Trial name
- e-Resiliencia (NCT06724770)
- Testing
- Resilience training intervention
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Irene Carrillo Murcia
Endometriosis
Study of the Influence of the Mediterranean Diet on the Quality of Life of Patients With Endometriosis.
The severities of chronic disease symptoms correlate with the levels of analytical parameters of inflammation. Studies have been published in which the Mediterranean diet has an anti-inflammatory phenomenon, decreasing…
- Trial name
- NCT07270393
- Testing
- Diet supplementation
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Biogipuzkoa Health Research Institute
Papilloma Viral Infection, CIN1
Evaluation Of The Efficacy Of The Combination Of GLIZIGEN® Oral Solution 1/Day And Vaginal Gel 1/Night For 2 Months In Patients With Cervical Intraepithelial Neoplasia Grade 1 (LSIL/CIN-1) Caused By High-Risk Human Papillomavirus (HPV-AR)
HPV infection can lead to cancer, especially when precancerous lesions have developed and high-risk HPV is present. Glizigen is an oral and intravaginal treatment based on activated glycyrrhizinic acid that has shown potential…
- Conditions
- Papilloma Viral Infection, CIN1, LSIL, Low Grade Squamous Intraepithelial Lesion
- Trial name
- NCT05916911
- Testing
- Glizigen
- Where
- 4 sites in Spain
- Volunteers
- 120 people
- Sponsor
- Catalysis SL