Clinical trials: Complication of Surgical Procedure
Miscarriage
Misoprostol in Termination of First Trimester Missed Abortion
The purpose of this study is to determine whether oral versus vaginal misoprostol is effective in termination of first trimester missed abortion and to compare between two different routes.
- Trial name
- NCT00797693
- Testing
- Misoprostol ( Cytotec) 200 microgram a tablet
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Hawler Medical University
Complication of Surgical Procedure, Pacemaker Complication
Key Factors of Leadless Pacemaker Implantation With Implantation Site, Complications and Prognosis
To investigate the relationship between key variables in leadless pacemaker implantation with implantation site, intraoperative complications and prognosis.
- Conditions
- Complication of Surgical Procedure, Pacemaker Complication, Pacemaker Syndrome
- Trial name
- NCT05761821
- Testing
- Leadless pacemaker
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Surgical Site Infection
Understanding the Drivers of Surgical Site Infection: Investigating and Modeling the Swissnoso Surveillance Data
Surgical site infection (SSI) is the most common healthcare-associated infection, multifactorial in nature, and a typical preventable harm.
- Trial name
- WATUSSI (NCT03883009)
- Where
- Switzerland
- Volunteers
- 318,000 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Postoperative Delirium, Postoperative Cognitive Dysfunction
Greek Validation of ACE III Test in Perioperative Patients
Postoperative neurocognitive disorders, including postoperative delirium (POD) and postoperaive cognitive dysfunction (POCD), are common complications of perioperative neurocognition in elderly patients undergoing surgery.
- Trial name
- NCT04312516
- Where
- Greece
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Glycemic Control, Surgical Site Infections
A Quality Initiative to Improve Glycemic Control in Diabetic and Non-Diabetic Insulin Study
The aim of this study is to examine the effect of moderate glucose (blood sugar) control in diabetic and non-diabetic patients undergoing leg bypass surgery (LEB) or open abdominal aortic aneurysm (AAA) repair.
- Conditions
- Glycemic Control, Surgical Site Infections, Cardiac Complications, Length of Stay
- Trial name
- NCT01916733
- Testing
- standard insulin protocol post-op (continuous IV insulin)
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Vermont Medical Center
Surgical Wound Infections, Colorectal Surgery
Minimization of Surgical Site Infections for Pts Undergoing Colorectal Surgery
This is a comparison, at this VA Hospital, of standard operating room management in colorectal surgery to a more rigid management using an additional five previously tested treatments to determine if this changes the rate of post…
- Trial name
- NCT00953784
- Testing
- standard operating management
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- Dallas VA Medical Center
Tranexamic Acid, Blood Loss, Surgical
Do Anesthesiologists Follow Guidelines on Perioperative Use of Tranexamic Acid?
Tranexamic acid has been used to reduce bleeding and transfusion for years. Randomized studies showed its efficacity in orthopedic surgery, trauma and post-partum hemorrhage.
- Conditions
- Tranexamic Acid, Blood Loss, Surgical, Blood Transfusion
- Trial name
- Periop_TXA (NCT05783648)
- Testing
- Use of tranexamic acid
- Where
- Belgium
- Volunteers
- 1,726 people
- Sponsor
- Erasme University Hospital
Stress Urinary Incontinence
Trial Comparing TVT SECUR System and Trans Vaginal Obturator Tape for Surgical Management of Stress Urinary Incontinence
To compare the efficacy and complications of the TVT SECUR system (TVT S) and trans-vaginal obturator tape (TVT-O) procedures for the surgical management of female stress urinary incontinence.
- Trial name
- NCT00527696
- Testing
- transvaginal obturator tape
- Where
- Canada
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Incisional Hernia After Midline Laparotomy, Quality of Life (QOL)
NoPro - Norwegian Hernia Prophylaxis Study
A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh.
- Conditions
- Incisional Hernia After Midline Laparotomy, Quality of Life (QOL), Burst Abdomen, Surgical Site Infections
- Trial name
- NoPro (NCT06858020)
- Testing
- Prophylactic polypropylene onlay mesh
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Sykehuset Innlandet HF
Surgical Site Infections, Lumbar Spinal Fusion
Adhesive Strips Vs Sutures in Skin Closure for Lumbar Spinal Fusion
Comparison between two methods for skin closure in lumbar spinal fusion surgery, a non-inferiority approach between sutures and adhesive strips and its effect on surgical site infections.
- Trial name
- NCT06664424
- Where
- Germany
- Volunteers
- 1,016 people
- Sponsor
- Diakonie-Klinikum Stuttgart
Pain, Postoperative, Surgery, Thoracic
Influence of Preoperative Support on Anxiety, Pain and Satisfaction With Postoperative Analgesia
The aim of this study was to analyze a relationship between information support provided by an interdisciplinary team and the levels of anxiety, pain and satisfaction with postoperative analgesia in children and adolescents…
- Trial name
- NCT03488459
- Testing
- Routine preoperative information from a nurse, Additional information support from a psychologist
- Where
- Poland
- Volunteers
- 112 people
- Sponsor
- National Institute for Tuberculosis and Lung Diseases, Poland
Surgical Site Infection, Difference in Surgical Site Infection According to Gender and Age Groups
COMPARISON OF PURSE-STRING CLOSURE VERSUS CONVENTIONAL PRIMARY CLOSURE FOLLOWING STOMA REVERSAL TO REDUCE SURGICAL SITE INFECTION RATE"
The study will be carried out in Surgical Unit-III, Lahore General Hospital, Lahore for one year . . Patients undergoing surgery for Ileostomy will be randomly divided into two groups, Group-A (Purse-string closure) and Group-B…
- Trial name
- NCT04757623
- Testing
- Purse string closure of Ileostomy
- Where
- 2 sites in Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Combined Military Hospital, Pakistan
Analgesia, Obstetrical, Coagulation Defect; Postpartum
IV Ketorolac on Platelet Function Post-Cesarean Delivery
Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption.
- Conditions
- Analgesia, Obstetrical, Coagulation Defect; Postpartum, Nonsteroidals (NSAIDs)Toxicity, Postpartum Hemorrhage
- Trial name
- KetoPltAgg (NCT03805607)
- Testing
- Ketorolac Tromethamine 30 MG/ML
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Open Abdomen, Incisional Hernia
Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy
The aim of this clinical trial is to evaluate whether placement of a synthetic prophylactic onlay mesh during definitive fascial closure can reduce the incidence of incisional hernia in adult patients managed with an open abdomen…
- Conditions
- Open Abdomen, Incisional Hernia, Definitive Fascial Closure, Emergency Abdominal Surgery
- Trial name
- SHIELD (NCT07835334)
- Testing
- Definitive Fascial Closure Without Prophylactic Mesh, Prophylactic Onlay Mesh Placement
- Volunteers
- 30 people
- Sponsor
- Hospital San Juan de Dios Tenerife
Maxillary Sinus Augmentation
Maxillary Sinus Elevation and Perioperative Complications
This study aims to investigate the effects of various external sinus lifting techniques on patient comfort and perioperative complications.
- Trial name
- NCT06601816
- Testing
- maxillary sinus lift with reamer, maxillary sinus lift with piezzo, maxillary sinus lift with conventional burr
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Ordu University
Ovarian Cancer
Tranexamic Acid in Surgery of Advanced Ovarian Cancer
The purpose of the study is to determine if a standardized single dose tranexamic acid given intravenously immediately preoperatively reduces the perioperative bleeding volume and reduces the need of blood transfusion in women…
- Trial name
- NCT00740116
- Testing
- Tranexamic acid, 0.9% NaCl solution
- Where
- 3 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Preben Kjolhede, MD, professor
Colorectal Neoplasm, Anemia
Intravenous Iron: Measuring Response in Anemic Surgical Patients
20 Patients will be recruited with confirmed colorectal adenocarcinoma and anemia who are planned to undergo surgery. All patients will be treated with a single dose of 1g intravenous ferric carboxymaltose (FERINJECT).
- Trial name
- NCT02057471
- Testing
- Intravenous ferric carboxymaltose
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Femur Fracture, Periprosthetic Fracture of Hip
Dose-Response Association Between Cerclage Wire Number and Infection Risk
The purpose of this dual-center retrospective study is to investigate the relationship between the number of metallic cerclage wires used in femoral fracture surgery and the risk of developing deep infections.
- Conditions
- Femur Fracture, Periprosthetic Fracture of Hip, Periprosthetic Fracture of the Femur, Surgical Site Infection (SSI)
- Trial name
- C-INFECT (NCT07434258)
- Testing
- 1 Metallic Cerclage Wiring, 2 metalic cerclage wire, 3 metalic cerclage wire
- Volunteers
- 148 people
- Sponsor
- Istanbul University
Phantom Limb Pain
Short Term Effect of Post Surgical Treatment of Mirror Therapy of Phantom Limb Pain
The aim of the study is the measurement of the short term effect of post surgical mirror therapy concerning pain intensity and frequency of patients with upper or lower amputation in comparison to standard occupational or…
- Trial name
- PPSS (NCT01913899)
- Testing
- Occupational/ physical therapy, Mirror therapy
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Ruhr University of Bochum
Pain, Postoperative
A Multicentre, Double-Blind, Double-Dummy, Randomised Study of the Analgesic Efficacy and Safety of Valdecoxib Compared to Diclofenac Sodium in Patients Undergoing Knee Arthroscopy for Anterior Cruciate Ligament (ACL) Reconstruction
To demonstrate non-inferiority of valdecoxib 20 mg twice daily (BID) (with an initial loading dose of 40 mg followed by a second dose of 20 mg on the first day only) with diclofenac sodium delayed release 75 mg BID in analgesic…
- Trial name
- NCT00650598
- Testing
- valdecoxib, diclofenac
- Where
- 25 sites in Australia, Hong Kong and 7 more
- Volunteers
- 328 people
- Sponsor
- Pfizer