Clinical trials: Complication of Hemodialysis
End-stage Kidney Disease, Kidney Disease, Chronic
Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD
The purpose of this study is to find out if empagliflozin, a new diabetic medication that has been shown to be very effective in lowering the risk of heart failure, is safe and tolerated in dialysis patients.
- Conditions
- End-stage Kidney Disease, Kidney Disease, Chronic, Dialysis, Diabetic
- Trial name
- NCT05614115
- Testing
- Empagliflozin
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Utah
Fatigue, Sleep Disturbance
Comparing Effect of Intradialytic Aerobic Exercise Versus Incentive Spirometer on Fatigue and Sleep Quality Among Hemodialysis Patients.
In order to accomplish the objectives of this investigation, a single-blind experimental comparative design was implemented to evaluate the impact of intradialytic aerobic exercise and Incentive Spirometer on sleep quality and…
- Conditions
- Fatigue, Sleep Disturbance, Hemodialysis Complication
- Trial name
- NCT07386691
- Testing
- intradialytic aerobic exercise versus incentive spirometer
- Where
- Iraq
- Volunteers
- 169 people
- Sponsor
- University of Baghdad
Hemodialysis, Coronary Arterial Disease (CAD)
Predictive Tools for the Presence of Significant Coronary Artery Disease Requiring Intervention in Chronic Hemodialysis Patients
Medical record data of all HD patients undergoing coronary angiography (CAG) at King Chulalongkorn Memorial Hospital between January 2017 and March 2021 were retrospectively reviewed as a discovery cohort to identify factors…
- Conditions
- Hemodialysis, Coronary Arterial Disease (CAD), ESRD (End Stage Renal Disease)
- Trial name
- CAD in HD (NCT06661941)
- Where
- Thailand
- Volunteers
- 149 people
- Sponsor
- Chulalongkorn University
Chronic Kidney Disease, End-Stage Renal Disease
Pharmacokinetics of Somatropin in Patients With End Stage Renal Disease Receiving Chronic Haemodialysis
This trial is conducted in Europe. The aim of this trial is to to compare steady-state total growth hormone (GH) exposure in haemodialysis (HD) patients with that of matched healthy subjects.
- Conditions
- Chronic Kidney Disease, End-Stage Renal Disease, Healthy
- Trial name
- NCT01502137
- Testing
- somatropin
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- Novo Nordisk A/S
Acute Kidney Injury
Standard Versus Accelerated Initiation of Dialysis in Acute Kidney Injury
The objectives of this trial are to determine whether, in critically ill patients with severe acute kidney injury (AKI), randomization to accelerated initiation of renal replacement therapy (RRT), compared with standard…
- Trial name
- STARRT-AKI (NCT01557361)
- Testing
- Accelerated RRT initiation, Standard RRT initiation
- Where
- 11 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Unity Health Toronto
Hyperuricemia, Hemodialysis Complication
Use of Febuxostat in Hyperuricemia Among Hemodialysis Patients
Hyperuricemia is not infrequently encountered among hemodialysis patients. However, there is no clear data about use of febuxostat among hemodialysis patients, apart from very small case series.
- Trial name
- NCT03149939
- Testing
- Febuxostat 40 milligramsTablet
- Volunteers
- 19 people
- Sponsor
- Benha University
Malnutrition, Complication of Hemodialysis
Intradialytic Parenteral Nutrition in Hemodialysis Patients
Malnutrition is a major cause of death in chronic hemodialysis patients. Primary treatment of malnutrition in these patients is dietetic counseling, additional enteral nutrition and occasionally drug therapy.
- Trial name
- IDPNHD (NCT00501956)
- Testing
- Intradialytic Parenteral Nutrition (IDPN)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Fresenius Kabi
End-stage Renal Disease, Kidney Failure, Chronic
Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With End-Stage Renal Disease
The purpose of this study is to assess the safety and efficacy of a novel, tissue-engineered vascular prosthesis, the Human Acellular Vascular Graft, HAVG.
- Trial name
- NCT01840956
- Testing
- HAVG
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Humacyte, Inc.
End-stage Renal Disease, Hemodialysis
Protein-bound Toxin Removal Between Limited Blood Flow Super High-flux Online HDF and High-Efficiency Online HDF
High-efficiency post-dilution online hemodiafiltration (OL-HDF) using high-flux dialyzer and requiring high blood flow rate (BF ≥400 mL/min) has been reported to enhance protein-bound toxin and middle molecular toxin removal and…
- Trial name
- NCT03288922
- Testing
- Limited BF OL-HDF with SHF, High-efficiency OL-HDF
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Chulalongkorn University
End Stage Renal Disease, Thrombosis
Safety and Efficacy Study of AB002 (E-WE Thrombin) in End Stage Renal Disease Patients on Chronic Hemodialysis
This study evaluates the safety and efficacy of AB002 (E-WE thrombin) in patients with end stage renal disease on chronic hemodialysis. Two dose levels will be evaluated in two cohorts.
- Trial name
- NCT03963895
- Testing
- AB002 Dose 1, AB002 Dose 2
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Aronora, Inc.
Kidney Failure, Chronic
Effects of Intradialytic Exercise as Assessed by Bioimpedance Analysis and Blood Volume Monitoring
The purpose of this study is to examine the impact of exercise during dialysis using objective measures of fluid status determination, specifically bioimpedance analysis (BIA) and blood volume monitoring (BVM).
- Trial name
- NCT01273753
- Testing
- Intradialytic exercise
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Michigan
Peripheral Artery Disease, End Stage Renal Disease on Dialysis
A Cross-Sectional Study to Assess Walking Performance in Subjects With Peripheral Artery and End Stage Kidney Disease
A cross-sectional, non-interventional study to assess walking performance, vascular function, and lower limb calcification in subjects with peripheral artery disease and end-stage kidney disease (PAD-ESKD) receiving hemodialysis.
- Trial name
- NCT04487301
- Where
- 7 sites in United States
- Volunteers
- 36 people
- Sponsor
- Sanifit Therapeutics S. A.
Kidney Failure, Chronic
Intradialytic Exercises During Hemodialysis
Aim. To investigate the effect of an intradialytic aerobic and resistance cycling exercise program (IARCEP) on depression, fatigue, and quality of life (QOL) in end-stage renal disease (ESRD) patients receiving haemodialysis, and…
- Trial name
- NCT02908594
- Testing
- Medical Exercise Peddler 3000, Medi-Bike, Taiwan
- Volunteers
- 76 people
- Sponsor
- Cardinal Tien Hospital
Hemodialysis
CR845-100303: Study to Assess the Potential of Physical Withdrawal From Intravenous CR845 (Difelikefalin) in Hemodialysis Patients
This is a multicenter, randomized, double-blind, placebo-controlled study to assess the potential of physical withdrawal from CR845 upon treatment discontinuation after 3 weeks of IV administration at a dose of 0.5 mcg/kg in…
- Trial name
- NCT05533008
- Testing
- CR845 0.5 mcg/kg
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- Cara Therapeutics, Inc.
Chronic Kidney Disease 5D
Feasibility of a Randomized Cluster Trial for Blood Pressure Targets in In-centre Hemodialysis Units
High blood pressure in people receiving hemodialysis is known to contribute to heart disease and heart-related death from strokes, heart failure, left ventricular hypertrophy (which is a thickening of the heart wall that makes it…
- Trial name
- NCT06695611
- Testing
- Increase systolic blood pressure, Decrease systolic blood pressure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
End Stage Renal Failure on Dialysis
A Pilot Trial of Twice-weekly Versus Thrice-weekly Hemodialysis in Patients With Incident End-stage Kidney Disease
The optimal frequency of hemodialysis treatments in patients with incident end-stage kidney disease in not known. This pilot trial will randomize patients with incident end-stage kidney disease due to chronic kidney disease…
- Trial name
- TWOPLUS-HD (NCT03740048)
- Testing
- Hemodialysis, Patiromer Oral Product
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Secondary Hyperparathyroidism
A Study to Evaluate the Effect of ASP7991 in Secondary Hyperparathyroidism Patients Undergoing Hemodialysis
To examine efficacy and safety after 12-week administration of ASP7991 in secondary hyperparathyroidism patients undergoing hemodialysis
- Trial name
- NCT02133404
- Testing
- ASP7991, Cinacalcet
- Where
- 6 sites in Japan
- Volunteers
- 62 people
- Sponsor
- Astellas Pharma Inc
Chronic Kidney Diseases, Hemodialysis
Efficiency of Combined Rehabilitation Programs Including Resistance and Endurance Exercises on Functional Capacities, Quality of Life and Daily Level of Activities in Hemodialysis Patients
Hemodialysis patients display among the lowest level of daily activities and decline of functional abilities is highly correlated with mortality.
- Conditions
- Chronic Kidney Diseases, Hemodialysis, Physical Rehabilitation
- Trial name
- DIALEX (NCT04538248)
- Testing
- Combined rehabilitation during hemodialysis
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Montpellier
Non-Dialysis Dependent Severe Renal Dysfunction, Cardiovascular Disease
Preop Hemodialysis or Intraop Ultrafiltration for Patients With Severe Renal Dysfunction Undergoing Open Heart Surgery
The purpose of this study is to determine whether preoperative hemodialysis or intraoperative modified ultrafiltration are effective for patients with non-dialysis dependent severe renal dysfunction undergoing open heart surgery.
- Trial name
- SeRenaD-CPB (NCT00720967)
- Testing
- Open Heart Surgery (OHS), Intraoperative Modified Ultrafiltration (MUF), Hemodialysis (HD)
- Where
- 7 sites in France, Germany and 3 more
- Volunteers
- 450 people
- Sponsor
- University Hospital, Geneva
Kidney Failure, Chronic, Renal Dialysis
Intradialytic Versus Home-Based Exercise in Female Hemodialysis Patients
This randomized controlled trial compared intradialytic exercise with home-based exercise in married female patients receiving maintenance hemodialysis.
- Trial name
- NCT07716436
- Testing
- Intradialytic Exercise, Home-Based Exercise
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.