Clinical trials: Communication Disorders
Primary Progressive Aphasia
Remotely Supervised Transcranial Direct Current Stimulation (tDCS) for Primary Progressive Aphasia (PPA)
The purpose of this study is to establish the feasibility of a program of remotely supervised transcranial direct current stimulation (RS-tDCS) paired with language skills practice for people living with the semantic or logopenic…
- Trial name
- NCT05615922
- Testing
- Transcranial Direct Current Stimulation (tDCS), Word-Naming Activity
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- NYU Langone Health
Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder
Home Play-based Intervention for Parents and Infants
The goal of this clinical trial is to learn whether a 12-week home-based intervention (Sociometric Play-based Remediation of Individual Neurodevelopmental Trajectories (SPRINT)) helps support parenting and the development of…
- Conditions
- Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder, Premature Birth, Global Developmental Delay
- Trial name
- SPRINT (NCT07716072)
- Testing
- SPRINT Intervention, Waitlist Protocol
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Nanyang Technological University
Autism Spectrum Disorder, Apraxia of Speech
Video Assisted Speech Technology to Enhance Motor Planning for Speech
Nearly 3.5 million Americans are diagnosed with Autistic Spectrum Disorder (ASD), a communication disorder that causes skill limitations in the areas of language acquisition, sensory integration, and behavior.
- Trial name
- VAST (NCT04764539)
- Testing
- Video Assisted Speech Therapy (VAST)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- iTherapy, LLC
Speech, Psychiatric Disorder
Speech-based Digital Biomarker for Psychiatric Disease
The general objectives of this study are to build a proof-of-concept, speech-based, digital biomarker for identifying the presence and tracking the severity of psychiatric disease.
- Conditions
- Speech, Psychiatric Disorder, Language
- Trial name
- NCT04851912
- Testing
- Winterlight Apps
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Winterlight Labs
Critical Illness
Integrated Supportive and Palliative Care for Older Adults in the ICU
The National Academy of Medicine and the National Institutes of Health have called for urgent action to improve the care delivered to the nearly 1,000,000 older Americans who die in intensive care units (ICUs) annually, or…
- Trial name
- ProPACC (NCT04921631)
- Testing
- Early Integration of Specialty Palliative Care with Critical Care
- Where
- United States
- Volunteers
- 1,091 people
- Sponsor
- University of Pittsburgh
COPD
Impact of a Peer Support Program Amongst COPD Patients and Their Caregivers
The study is to compare the effectiveness of two health communication and dissemination strategies that are designed to engage patients and family caregivers in successfully managing COPD in 'real-world' settings.
- Trial name
- NCT02891200
- Testing
- Peer support program, HCP support
- Where
- 2 sites in United States
- Volunteers
- 292 people
- Sponsor
- Johns Hopkins University
Stroke, Caregiver Burnout
Ecological Momentary Intervention for Stroke Caregivers' Psychological Support
The proposed trial aims to evaluate the effectiveness of internet-delivered cognitive behavioural therapy (iCBT) based ecological momentary intervention (EMI) for psychological well-being in stroke family caregivers.
- Conditions
- Stroke, Caregiver Burnout, Depressive Symptoms, Psychological Distress
- Trial name
- NCT04936828
- Testing
- iCBT-based EMI
- Where
- 7 sites in Hong Kong
- Volunteers
- 256 people
- Sponsor
- The University of Hong Kong
Aphasia
Effect of Dopaminergic Medication on Recovery of Aphasia
The investigators have been offering computer assisted therapy of aphasia (CAT) as a complement to traditional treatments to aphasia patients of the "Service of Neurorehabilitation" for some years.
- Trial name
- NCT00941265
- Testing
- levodopa and benserazide
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Stroke, Aphasia
Effects of rTMS Based on Neural Activation in Language Performance in Stroke Patients With Non-fluent Aphasia
The aim of this study is to assess the safety and clinical efficacy of repetitive transcranial magnetic stimulation (rTMS) based on hemodynamic brain activity pattern with functional near infrared spectroscopy (fNIRS) in early…
- Trial name
- NCT02591719
- Testing
- MagPro magnetic stimulator (HF rTMS), MagPro magnetic stimulator (LF rTMS)
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Seoul National University Bundang Hospital
Prelingual Deafness, Retention Disorders, Cognitive
Mini-Mental State (MMS-LS) and Sign Language
In France the prevalence of pre-lingual deafness is between 1 and 1.4 per 1000 habitants, and according to very conservative estimates, about 44 000 deaf persons use the sign language.
- Trial name
- MMS-LS (NCT02005679)
- Testing
- application of the mini-mental state test
- Where
- 4 sites in France
- Volunteers
- 195 people
- Sponsor
- Lille Catholic University
Stroke, Aphasia
Improving Aphasia Using Electrical Brain Stimulation
Language and communication are essential for almost every aspect of human life, but for people who have aphasia, a language processing disorder that can occur after stroke or brain injury, even simple conversations can become a…
- Trial name
- NCT04963803
- Testing
- Active transcranial direct current stimulation (tDCS), Language Specific Attention Treatment
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Syracuse University
Stuttering
Computerized Based Analysis for Detection and Severity Assessment of Stuttering
In the light of previous attempts to design and develop automated and objective measures for automatic speech recognition system that detects disfluent speech and assess its severity, yet fully automated measurement of stuttered…
- Trial name
- NCT05437627
- Testing
- The Arabic version of Stuttering Severity Instrument-3 (ASSI3) for children and adults
- Volunteers
- 120 people
- Sponsor
- Assiut University
Breast Cancer
The Attitudes, Communication, Treatment and Support Intervention to Reduce Breast Cancer Treatment Disparity
The ACTS (Attitudes, Communication, Treatment, Support) Intervention is a onetime, intensive psycho-educational intervention using a race-matched breast cancer survivor interventionist to: address Attitudes, including perceptions…
- Trial name
- ACTS (NCT01184066)
- Testing
- ACTS Intervention, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 141 people
- Sponsor
- University of Pittsburgh
Aphasia, Stroke
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
The purpose of this study is to assess changes in language abilities of participants with chronic, post-stroke aphasia following an 8-week therapy period combined with brain stimulation.
- Trial name
- NCT04142866
- Testing
- Anodal transcranial direct current stimulation, Speech-Language Therapy (SLT)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- City University of New York
Critical Illness, Communication Disabilities
Enhancing & Mobilizing the POtential for Wellness & Emotional Resilience Among Surrogate Decision-Makers of ICU Patients
Intensive Care Units (ICU) are stressful places where life-and-death medical decisions are made and patients' surrogate decision-makers are exposed to potentially traumatic experiences.
- Trial name
- EMPOWER (NCT03276559)
- Testing
- EMPOWER, Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Psychotic Disorders, Schizophrenia
Participatory Video as a Recovery-Oriented Intervention in Early Psychosis
Prior research has shown that people with psychotic illnesses, like schizophrenia, who make sense of and meaningfully integrate their psychotic experiences into their life story are more likely to recover from their illness.
- Trial name
- NCT02360566
- Testing
- Participatory Video Intervention for Early Psychosis
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Stuttering, Adult
Lumateperone in the Treatment of Stuttering, Childhood Onset Fluency Disorder
The primary objective of this study is to evaluate the efficacy and tolerability of Lumateperone in reducing stuttering symptoms. The following scales and samples will be collected for clinical and functional outcomes.
- Trial name
- NCT07734103
- Testing
- Lumateperone (ITI-007)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- CSTrials Inc.
Critical Illness, Communication
Communication With Mechanically Ventilated Intensive Care Patients
The overarching aim of this multicenter study is to develop a multimodule training intervention (COMMEC-ICU) for nurses working in ICUs, to increase nurses skills and knowledge and then improve communication for mechanically…
- Conditions
- Critical Illness, Communication, Intensive Care Unit Syndrome
- Trial name
- COMMEC-ICU (NCT06977555)
- Testing
- Communication Course and skills training
- Where
- Norway
- Volunteers
- 500 people
- Sponsor
- Oslo University Hospital
Articulation Disorders
Correlation Between Deficits in Knee ROM Recovery and Difficulty in Dorsiflexing the Tibio-tarsal Joint in Patients Undergoing Total Knee Replacement Surgery.
To demonstrate that the deficit in dorsiflexion-tibia-talar joint range of motion can have an effect on the knee operated by arthroplasty by limiting full extension and, in general, the recovery of a full range of motion.
- Trial name
- NODORSIFLEX (NCT07016243)
- Where
- Italy
- Volunteers
- 197 people
- Sponsor
- Istituto Ortopedico Rizzoli
Prostate Cancer Stage I, Kidney Cancer Stage I
Patient-Centered Communication of Life Expectancy Estimates in Genitourinary Malignancies
Investigators will conduct a randomized trial to determine if providing patient-specific life expectancy estimates during treatment counseling via a targeted, patient-centered communication approach improves shared decision…
- Conditions
- Prostate Cancer Stage I, Kidney Cancer Stage I, Bladder Cancer Stage II, Prostate Cancer Stage II
- Trial name
- NCT03522155
- Testing
- Patient-centered communication of life expectancy
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Cedars-Sinai Medical Center