Clinical trials: Common Cold
Chronic Rhinitis, Non-allergic Rhinitis
A Randomized Controlled Trial Comparing Posterior Nasal Nerve Ablation Procedures for Chronic Rhinitis
The goal of this clinical trial is to learn which procedural intervention most effectively reduces symptoms of chronic rhinitis (non-allergic rhinitis) in adult patients (18 years and older).
- Trial name
- NCT07706595
- Testing
- RhinAer, Neuromark, Clarifix
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Common Cold, Pharyngitis
Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Throat Associated With a Common Cold
The purpose of this study is to determine the efficacy and safety of 1000 mg Aspirin (study medication) by comparing 1000 mg Paracetamol (study medication) in treating the symptoms of sore throat associated with a common cold.
- Conditions
- Common Cold, Pharyngitis, Tonsillitis
- Trial name
- NCT01465009
- Testing
- Acetylsalicylic acid (Aspirin, BAYE4465), Paracetamol
- Where
- 8 sites in United Kingdom
- Volunteers
- 508 people
- Sponsor
- Bayer
Upper Respiratory Infection, Common Cold
The Natural History of Viral Upper Respiratory Infections in Children Aged 6 to Less Than 14 Years
This study examines the cold processes of children aged 6 to less than 14. Children will be seen by the study staff 6 days in a row during the course of their naturally-acquired colds.
- Trial name
- NCT00405509
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- West Penn Allegheny Health System
Acute Nasopharyngitis
A Controlled Human Rhinovirus Infection Study of 2-Deoxy-D-Glucose in Healthy Adults
2-DG-02 is a randomized, placebo-controlled, double-blind Phase 2 study to investigate the efficacy and safety of 2-Deoxy-D-Glucose as a pre-exposure prophylaxis using the rhinovirus challenge model in healthy study participants.
- Trial name
- NCT06375772
- Testing
- 2-Deoxy-D-glucose
- Where
- Netherlands
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- G.ST Antivirals GmbH
Common Cold
Study to Evaluate the Efficacy of EZC Pak in Adults With Upper Respiratory Infection (URI)
A randomized-controlled interventional clinical trial to evaluate the effectiveness of EZC Pak \& EZC Pak+D for the treatment of the common cold and/or a URI.
- Trial name
- NCT04943575
- Testing
- EZC Pak, EZC Pak +D
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- PPC Pharmaceuticals
Upper Respiratory Tract Infection, COVID-19
Elderberry for Immune Support
The purpose of this study is to confirm and quantify the effects of ElderCraft® elderberry extract on immune health.
- Conditions
- Upper Respiratory Tract Infection, COVID-19, Flu, Flu Like Illness
- Trial name
- NCT05435144
- Testing
- Elderberry
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Antioxidative Stress, Cold
Taxifolin/Ergothioneine and Immune Biomarkers in Healthy Volunteers (TaxEr)
The complexities of the immune system make measuring the impact of dietary interventions upon its function challenging. The immune system is highly responsive to environmental influences, including the diet.
- Conditions
- Antioxidative Stress, Cold, Influenza, Aging
- Trial name
- TaxEr (NCT05190432)
- Testing
- Taxifolin, Ergothioneine, Control
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Respiratory Tract Diseases
Study of Echinaforce Junior Tablets in Children With Acute Colds
This study aims to investigate safety and efficacy of Echinaforce Junior tablets in two dosages of 3 x 1 and 5 x 1 tablets per day in children 4 - 12 years old with acute colds.
- Trial name
- NCT02198391
- Where
- Switzerland
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- A. Vogel AG
Common Cold
Echinaforce Junior Bioavailability Trial
In this bioavailability trial should be shown that the one of the main active constituent in alcoholic echinacea extracts, the alkylamide dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamide (short: tetraen) is bioavailable in…
- Trial name
- NCT03070314
- Testing
- Echinaforce junior
- Where
- Switzerland
- Sponsor
- A. Vogel AG
Respiratory Infections
Omega-Cold Supplementation With Free Fatty Acids for the Prevention of Respiratory Infections in Adults.
The purpose of this study is to investigate whether fish oil containing free fatty acids affects people's susceptibility to viral infections such as colds, influenza, and COVID-19, as well as the course of these illnesses.
- Trial name
- OmegaCold FFA (NCT07314593)
- Testing
- Omega-3 oil with 2% Free Fatty Acids, Vegatable oil
- Where
- Iceland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Common Cold
Efficacy and Safety of Resveratrol and Carbossimetyl Beta Glucan in Treatment of Upper Airways Disease in Infancy
outpatient infants (0-6 months of life), affected by symptoms of upper airways disease will be randomly assigned to two type of intervention: A: treatment group, receiving resveratrol and carbossimetyl beta glucan; B: control…
- Trial name
- VIRNEO (NCT03683108)
- Testing
- Resveratrol and Carbossimetyl Beta Glucan, Saline Solution
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Common Cold, Nasal Mucosal Inflammation
Post Market Clinical Follow-Up Study - Medical Device KalobaNaso
The goal of this observational PMCF study is to confirm the efficacy and safety of the medical device KalobaNaso (a nasal spray) in children, adolescents and adults with common cold symptoms, such as runny nose, nasal congestion…
- Conditions
- Common Cold, Nasal Mucosal Inflammation, Rhinitis
- Trial name
- PMCF (NCT05960318)
- Testing
- KalobaNaso spray, KalobaNaso junior spray
- Where
- Italy
- Volunteers
- 131 people
- Sponsor
- Schwabe Pharma Italia
Respiratory Tract Infections, Common Cold
Stopping Upper Respiratory Infections and Flu in the Family: The Stuffy Trial
Colds and flu cause much loss of work and school. The purpose of this study is to try to reduce the transmission of colds and flu among household members with one of three interventions: some educational material, educational…
- Trial name
- STUFFY (NCT00448981)
- Testing
- Education, Hand Sanitizer, Face Masks
- Where
- United States
- Volunteers
- 2,788 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Healthy
A Study Investigating the Safety and Efficacy of Bio-Active Silver Hydrosol™ in Providing Immune Support
The objective of this study is to investigate the ability of Bio-Active Silver Hydrosol™ in providing immune support in healthy adult males and females participating in intense aerobic exercise.
- Trial name
- NCT04144673
- Testing
- Silver Hydrosol
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Natural Immunogenics Corp.
Healthy
Galactooligosaccharide, Immune Strength, and Digestive Health
The purpose of this research study is to determine whether a functional fiber, galactooligosaccharide, can help maintain immune strength and digestive health in undergraduate students who are undergoing an academic stress (i.e.…
- Trial name
- NCT01137760
- Testing
- Sucrose, Galactooligosaccharide
- Where
- United States
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- University of Florida
Common Cold
Effect of Probiotic on the Innate and Adaptive Host Response to Rhinovirus (EPIARR)
The study is designed to assess the effect of ingestion of a probiotic on innate and adaptive host responses to rhinovirus infection.
- Trial name
- EPIARR (NCT01669603)
- Testing
- Bifidobacterium lactis Bl-04, Rhinovirus
- Where
- United States
- Volunteers
- 789 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Common Cold
Study Comparing 3 Formulations to Evaluate the Efficacy and Safety of the Inflammatory Symptoms of the Upper Respiratory Tract, in Children Between 2 and 6 Years Old
The primary outcome of this study is to evaluate the clinical efficacy of the dose fixed combination and each drug, that composes it, isolated, regarding the respiratory symptoms improvement in superior air passages acute…
- Trial name
- NCT00967759
- Testing
- Bronpheniramine and fenilefrine (Decongex Plus), Bronpheniramine isolated, Fenilefrine isolated
- Where
- Brazil
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Upper Respiratory Tract Infections, Gastrointestinal Infection
Preventive Effect of Cow's Milk Fermented With Lactobacillus Paracasei CBA L74 on Common Infectious Diseases in Children
this is a double-blind randomized placebo controlled clinical trial. 200 healthy children aged 12-48 months, attending day care or preschool for at least 5 days a week, regularly checked by the family pediatrician (FP) involved…
- Conditions
- Upper Respiratory Tract Infections, Gastrointestinal Infection, Children, Only
- Trial name
- FERCT19 (NCT05484102)
- Testing
- milk fermented with lactobacillus paracasei CBA L74
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Bari
Effects of; Cold
Role of Cryotherapy in Reduction of Post Operative Endodontic Pain Following Single Visit Root Canal Therapy
AIM : To determine the efficacy of cold saline irrigation in reduction of post operative pain following root canal therapy. METHODOLOGY : Forty patients requiring root canal treatment on permanent single rooted teeth were…
- Trial name
- NCT03044470
- Testing
- cryotherapy
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mamata Dental College
Common Cold
Mucinex Exploratory Cold Study
This is an exploratory, multicenter, randomized, blinded, placebo-controlled study of Mucinex in patients with colds. Patients will receive 7 days of treatment with either Mucinex or placebo.
- Trial name
- NCT01046136
- Testing
- guaifenesin (Mucinex)
- Where
- United States
- Volunteers
- 378 people
- Sponsor
- Reckitt Benckiser Inc.