Clinical trials: Colorectal Polyps
Colorectal Lesions
Evaluation of Capsule Endoscopy With PillCam® Colon 2 in Visualization of the Colon
This pilot, multi center study will establish the effectiveness of Given PillCam® Platform with the PillCam® Colon 2 Capsule as demonstrated by the identification of subjects with polyps, compared to standard colonoscopy.
- Trial name
- NCT01269372
- Testing
- PillCam Colon 2, Colonoscopy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Colonic Polyp, Colorectal Cancer
Computer Aided Diagnosis of Colorectal Polyps
The purpose of this study is to assess whether computer aided technology (CAD) can help in the diagnosis of polyps found the bowel compared with visual inspection alone and therefore whether it is beneficial in helping clinicians…
- Trial name
- EndoBrain (NCT04510545)
- Testing
- Endobrain, Computer Aided Diagnosis (CAD)
- Where
- United Kingdom
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Colorectal Polyps
Research on the Application of AI Image Recognition-Based Smartphone Apps in Personalized Bowel Preparation
Colorectal cancer, as one of the most common malignant tumors of the digestive system, has a high incidence and mortality rate worldwide.
- Trial name
- NCT06610630
- Testing
- Assessment of Bowel Preparation Using AI-Driven Smartphone Applications
- Where
- China
- Volunteers
- 513 people, healthy volunteers welcome
- Sponsor
- Jianning Yao
Colorectal Cancer, Polyp
Safety and Efficacy of the NaviAid™ G-Eye System During Colonoscopy
To evaluate the safety of using the NaviAid™ G-Eye system during Colonoscopy
- Conditions
- Colorectal Cancer, Polyp, Adenoma
- Trial name
- NCT01749722
- Testing
- NaviAid™ G-Eye procedure
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colorectal Polyp, Colonoscopy
Synergistic Effect of G-Eye Balloon for Behind the Folds Visualization With CADe (Discovery System) on Adenoma Detection Rate.
Colonoscopy is the gold standard for colorectal screening. The diagnostic accuracy of colonoscopy highly depends on the quality of inspection of the colon during the procedure.
- Conditions
- Colorectal Polyp, Colonoscopy, Artificial Intelligence, Adenoma
- Trial name
- DiscoveryIII (NCT05220345)
- Testing
- colonoscopy assisted by both balloon-Behind The Folds visualizing and Computer assisted detection (CADe)
- Where
- Netherlands
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Colon Cancer, Adenoma
Chemoprevention With Folic Acid
Colorectal neoplasia is the second most common cancer in the United States and other Western countries with about 140,000 newly diagnosed cases per year in the United States with a mortality rate of about 40%.
- Conditions
- Colon Cancer, Adenoma, Colonic Polyps
- Trial name
- NCT00018551
- Testing
- Folic Acid
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Colorectal Cancer, Colorectal Polyps
Does Inspection During Insertion Improve Adenoma Yields During Colonoscopy?
Colonoscopy is not a perfect test. It misses a substantial number of neoplastic lesions and has some risk of missing cancer. Nearly all work on detection during colonoscopy has focused on the withdrawal phase of the examination.
- Trial name
- NCT01035775
- Testing
- Inspection during insertion, Inspection during withdrawal
- Where
- 2 sites in United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colon Polyp, Adenoma Colon
AmplifEYE Colonoscopy vs Standard Colonoscopy
Colonoscopy screening is proven to reduce mortality rates for colorectal cancer, which relies on early detection and removal of colonic polyps.
- Conditions
- Colon Polyp, Adenoma Colon, Serrated Polyp, Colonic Neoplasms
- Trial name
- NCT03814369
- Testing
- AmplifEYE
- Where
- Hong Kong
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Colonic Lesions
Prospective Image Collection of Colorectal Polyps.
It concerns a study in which we wish to collect images and corresponding histological information (microscopic characteristics) in a prospective manner in various European and non-European centers (multicentric).
- Trial name
- NCT07401264
- Where
- Belgium
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colon Polyp, Colon Adenoma
Impact of Screen Size on Colorectal Adenoma Detection
The purpose of this study is to assess whether the use of large screen during colonoscopy will increase adenoma detection rate.
- Conditions
- Colon Polyp, Colon Adenoma, Colorectal Neoplasms
- Trial name
- NCT04749303
- Testing
- Large Screen
- Where
- Hong Kong
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Adenoma, Polyps
Prospective Trial to Compare ADR of G-EYE™ Colonoscopy With Standard Colonoscopy
The purpose of this study is to compare the adenoma detection rate (ADR) of the G-EYE™ colonoscopy with that of standard colonoscopy.
- Conditions
- Adenoma, Polyps, Colorectal Cancer
- Trial name
- NCT02545699
- Testing
- G-EYE™ Colonoscopy, Standard Colonoscopy
- Where
- Israel
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colorectal Cancer (CRC), Adenomatous Polyposis
Artificial Intelligence-assisted Colonoscopy in the Detection and Characterization of Colorectal Lesions
The study aims to evaluate the effectiveness of artificial intelligence-assisted colonoscopy in increasing adenoma detection rate and the accuracy in the characterization of colorectal lesions, compared to standard colonoscopy…
- Conditions
- Colorectal Cancer (CRC), Adenomatous Polyposis, Colorectal Lesions, Colorectal Cancer
- Trial name
- NCT07066046
- Testing
- Colonoscopy
- Where
- Brazil
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Colonic Polyps, Colorectal Neoplasms
Right Colon Enema to Improve Bowel Preparation Quality During Colonoscopy
Colonoscopy is a test that lets doctors look inside the large bowel to find and remove growths called polyps, which can develop into bowel cancer. Before the test, people take a bowel preparation to empty the bowel.
- Conditions
- Colonic Polyps, Colorectal Neoplasms, Colonoscopy, Bowel Preparation Quality
- Trial name
- RIGHT-CLEAN (NCT07813013)
- Testing
- Sodium phosphate enema, Water instillation
- Where
- 2 sites in Australia
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Westmead Hospital
Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms
The Impact of Image-Assisted Colonoscope on Patient Experience, Physician Workload, and Examination Quality
Colonoscopy is the cornerstone for colorectal cancer screening, diagnosis, and post-treatment surveillance. Procedural quality is influenced by patient anatomy, particularly variations in colonic configuration such as sigmoid…
- Conditions
- Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms, Difficult Colonoscopy, Colonoscopy-Related Discomfort
- Trial name
- LOOP-p1 (NCT07541924)
- Testing
- CT-Based Image-Assisted Colonoscope Insertion
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- DONG WU
Colorectal Cancer
CB-17-08 Augmented Endoscopy System for Mucosal Lesion Detection During Colonoscopy for Colon Rectal Cancer.
The aim of this study is to assess the performance of the CB-17-08 to help endoscopists find potential mucosal polyps during the colonoscopy procedure, without significant noise disturbing the endoscopist attention, nor negative…
- Trial name
- NCT03954548
- Testing
- CB-17-08 CADe
- Where
- 10 sites in United States, Italy and 1 more
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Cosmo Artificial Intelligence-AI Ltd
Adenomatous Polyps
A Comparison of the Resection Rate of Cold Snare Polypectomy for Large (10-15 mm) and Small (5-9 mm) Colorectal Polyps
Colorectal cancer remains the third most common cause of death from cancer worldwide. Colonoscopy allows removal of adenomatous polyps is the best colorectal cancer screening, according to the adenoma-carcinoma sequence.
- Trial name
- CSP (NCT03647176)
- Testing
- Cold snare polypectomy
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Yuqi He
Adenomatous Polyps
Curcumin for the Chemoprevention of Colorectal Cancer
Specific Aims: To determine if curcuminoids modulate cellular proliferation as measured by proliferating cell nuclear antigen (PCNA) in the colorectal mucosa of subjects with previously resected adenomatous colonic polyps.
- Trial name
- NCT00118989
- Testing
- Curcuminoids
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Colorectal Neoplasms, Colonic Polyp
Adenoma Detection Rate Using Endocuff Vision in China
The primary aim of this study is to explore the usefulness of Endocuff Vision in colonoscopy on adenoma detection rate (ADR). Other aims include to explore the data below when Endocuff Vision is used.
- Conditions
- Colorectal Neoplasms, Colonic Polyp, Adenoma
- Trial name
- SinoEVADR (NCT03839277)
- Testing
- Endocuff Vision
- Where
- 5 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Neoplasms, Colonic Polyps
Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities
The purpose of this study is to determine if a new device, called the Endocuff Vision (a small plastic device attached to the end of the colonoscope which helps by holding the folds of the bowel back to give a clear view of the…
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Adenoma
- Trial name
- ADENOMA (NCT02552017)
- Testing
- Endocuff Vision
- Where
- 7 sites in United Kingdom
- Volunteers
- 1,772 people, healthy volunteers welcome
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Colorectal Polyps
Comparison of Two Types of Biopsy Forceps for Obtaining Cold Biopsy Polypectomy for Small Sessile Colorectal Polyps Less Than 6 mm in Diameter
The purpose of this study is to evaluate the efficacy of the new RJ4 compare with the standard RJ3 biopsy forceps for performing polypectomy for small colorectal polyps.
- Trial name
- NCT00855790
- Testing
- evaluate the effectiveness of the RJ4 biopsy forcep versus the RJ3 biopsy forcep
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Florida