Clinical trials: Colorectal Polyp
Colonic Polyps
Computer Assisted Optical Assessment of Small Colorectal Polyps
The aim of the study is to develop a computer program which is able to distinguish between adenomatous and non- adenomatous polyps on the basis of optical features of the polyps.
- Trial name
- NCT02522702
- Testing
- Photography of polyps, resection of polyps
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Technical University of Munich
Colorectal Cancer, Colon Polyp
Colorectal Cancer Screening Using Stool DNA-based SDC2 Methylation Test
A study of colorectal cancer screening using stool DNA-based SDC2 methylation test
- Conditions
- Colorectal Cancer, Colon Polyp, Healthy
- Trial name
- NCT04304131
- Testing
- Earlytect Colon Cancer
- Where
- 8 sites in South Korea
- Volunteers
- 1,210 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Colorectal Cancer
Early Detection of Polyps and Colon Cancer by Fluorescence Imaging - a Dose-finding Study
Patients referred for colon inspection (colonoscopy) due to suspicion of colon polyps/cancer will receive local administration of hexaminolevulinate (HAL) prior to colon inspection.
- Trial name
- NCT00285701
- Testing
- hexaminolevulinate
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Photocure
Colorectal Cancer, Colorectal Polyp
Safety Of ColoRectal Assessment and Tumor Evaluation by Colon Capsule Endoscopy
Following European guidelines patients undergoing colonoscopy in one of Odense University Hospitals units will now be offered a colon capsule endoscopy (CCE) in case of incomplete examinations.
- Trial name
- SOCRATEC (NCT04307901)
- Testing
- Colon capsule endoscopy
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Odense University Hospital
Precancerous Condition
Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps
This randomized phase III trial is studying eflornithine and sulindac to see how well they work compared to a placebo in preventing colorectal cancer in patients with colon polyps.
- Trial name
- NCT00118365
- Testing
- eflornithine, sulindac, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 375 people
- Sponsor
- National Cancer Institute (NCI)
Colon Polyp, Colorectal Adenoma
9 Minutes for Tandem Colonoscopy Withdrawal
A mean withdrawal time of at least 6 minutes has been considered to be one of the critical quality criterions of colonoscopy. Recently, our group completed a multicenter randomized controlled trial, which proved that prolonging…
- Trial name
- NCT04797065
- Testing
- 6-minute then 9-minute withdrawal, 9-minute then 6-minute withdrawal
- Where
- China
- Volunteers
- 733 people
- Sponsor
- Changhai Hospital
Obstructing Colorectal Cancer
Preoperative Assessment for Synchronous Carcinoma or Polyps With Magnetic Resonance (MR) Colonography
The purpose of this study is to diagnose possible synchronous carcinomas and polyps with magnetic resonance (MR) colonography in patients booked for operation because of carcinoma in the descending or sigmoid colon, where a…
- Trial name
- NCT00300547
- Testing
- MR colonography
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Herlev Hospital
Colon Cancer Prevention, Polyp Colorectal
Delayed Surveillance Colonoscopy Following Piecemeal EMR
This multicenter, prospective, randomized non inferiority trial, conducted at four Israeli hospitals, will evaluate whether a relaxed surveillance strategy after piecemeal endoscopic mucosal resection (pEMR) of large non…
- Trial name
- NCT07328308
- Testing
- Colonoscopy after bowel cleansing
- Where
- Israel
- Volunteers
- 760 people
- Sponsor
- Rambam Health Care Campus
MASH - Metabolic Dysfunction-Associated Steatohepatitis
High-Risk Transcriptome Molecular Prediction Study of MASH-Associated Colorectal Polyps
The goal of this observational study is to learn about the molecular characteristics of colorectal polyps in patients with metabolic dysfunction-associated steatohepatitis (MASH) compared to individuals without fatty liver, and…
- Trial name
- NCT07463287
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai East Hospital
Polyps, Cardiovascular Diseases
Lifestyle and Dietary Pattern in Relation to Precursor Lesions of Colorectal Cancer and Cardiometabolic Diseases
The association between lifestyle and dietary patterns with precursor lesions of colorectal cancer and cardiometabolic diseases is still unclear.
- Trial name
- NCT03708952
- Where
- 2 sites in China
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Colonic Neoplasm
Narrow Band Imaging for Diagnosis of Proximal Serrated Polyps
Although colonoscopy is considered the gold standard for diagnosis of colonic polyps, the missed rate for colonic adenoma ranged from 15-32%.
- Trial name
- NCT01725321
- Testing
- Narrow band imaging
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colorectal Polyps
Confocal Laser Endomicroscopy With Topical Cresyl Violet for Colorectal Polyps
Probe-based confocal laser endomicroscopy (pCLE) has been shown to a reliable diagnostic method enabling in vivo microscopic imaging during ongoing endoscopy.
- Trial name
- NCT03620695
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shandong University
Colorectal Neoplasms, Intestinal Neoplasms
Usefulness of GI-GENIUS in FIT-based Colorectal Cancer Screening Program.
Deep learning technology has an increasing role in medical image applications and, recently, an artificial intelligence device has been developed and commercialized by Medtronic for identification of polyps during colonoscopy…
- Conditions
- Colorectal Neoplasms, Intestinal Neoplasms, Gastrointestinal Neoplasms, Colonic Polyp
- Trial name
- CADILLAC (NCT04673136)
- Testing
- GI-GENIUS Medtronic, Colonoscopy
- Where
- 6 sites in Spain
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Asociación Española de Gastroenterología
Adenomatous Polyp, Crohn Disease
Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease
This study is being done to evaluate single incision laparoscopic surgery (SILS) for colorectal diseases, compared to multi-port laparoscopic surgery.
- Conditions
- Adenomatous Polyp, Crohn Disease, Familial Adenomatous Polyposis, Hereditary Intestinal Polyposis Syndrome
- Trial name
- NCT01656746
- Testing
- therapeutic laparoscopic surgery
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Colorectal Cancer, Familial Adenomatous Polyposis
Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis
This randomized phase II trial studies how well giving celecoxib with or without eflornithine works in preventing colorectal cancer in patients with familial adenomatous polyposis.
- Trial name
- NCT00033371
- Testing
- Celecoxib, eflornithine, Laboratory biomarker analysis
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- National Cancer Institute (NCI)
Colorectal Neoplasm
Prevalence and Spectrum of Cancer Susceptibility Among Patients with Advanced Colorectal Polyps
The study is being conducted to determine the prevalence and risk factors for germline cancer susceptibility genetic mutations among patients with advanced colorectal polyps.
- Trial name
- NCT04160832
- Testing
- Multi-Cancer Cancer Panel
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Colorado, Denver
Cold Snare Resection, Hot Snare Resection
Efficacy and Safety Research of Cold Snare Polypectomy and Hot Snare Polypectomy in the Treatment of 4-9 mm Diameter Colorectal 0-Isp and 0-Ip Polyps: a Prospective, Multicenter, Randomized Controlled Study(FAST -REST Study)
This study will evaluate the efficacy and safety of cold snare polypectomy(CSP) and hot snare polypectomy(HSP) in the treatment of colorectal 4-9mm 0-Isp and 0-Ip polyps, and compare the complete resection rate, postoperative…
- Conditions
- Cold Snare Resection, Hot Snare Resection, Polyps of Colon
- Trial name
- NCT06658561
- Testing
- cold snare polypectomy, hot snare polypectomy
- Where
- China
- Volunteers
- 982 people
- Sponsor
- Ruijin Hospital
Attenuated Familial Adenomatous Polyposis, Familial Adenomatous Polyposis
Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer
This phase II trial studies the side effects of erlotinib hydrochloride and how well it works in reducing duodenal polyp burden in patients with familial adenomatous polyposis at risk of developing colon cancer.
- Trial name
- NCT02961374
- Testing
- Erlotinib, Erlotinib Hydrochloride
- Where
- 8 sites in United States, Puerto Rico
- Volunteers
- 46 people
- Sponsor
- National Cancer Institute (NCI)
Colonic Neoplasms
Artificial Intelligence for Leaving in Situ Colorectal Polyps.
This two parallel-arms, randomized, multicenter trial is aimed at investigating safety and effectiveness of a Computer-Aided-Diagnosis (CADx)-assisted leave-in-situ strategy (Leave-In-Situ Arm) as opposed to a resect-all strategy…
- Trial name
- NCT05500248
- Testing
- Leave In Situ, Standard
- Where
- Italy
- Volunteers
- 919 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Colon Preparation, Polyps Colorectal
Efficacy And Tolerability Of Asymmetric Split Regimen For Bowel Preparation
The investigators aimed to compare the efficacy for bowel cleansing of a split-dose regimen with a low morning dose of PEG solution (Asymmetric; 25% of the dose is given on the day of the procedure and 75% of the dose is given on…
- Trial name
- NCT06916689
- Testing
- 1L PEG-Asc
- Where
- Italy
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- ASST Rhodense