Clinical trials: Colonoscopy Preparation
Bowel Preparation for Colonoscopy
Application of Linaclotide Capsule in Bowel Preparation for Colonoscopy
The clinical purpose of this study was to investigate whether the adjuvant application of linaclotide in bowel preparation for colonoscopy could improve the quality of bowel preparation or reduce the dosage of laxatives.
- Trial name
- NCT05291325
- Testing
- 3L PEG + Linaclotide, 3L PEG, 2L PEG + Linaclotide
- Where
- China
- Volunteers
- 1,607 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Bowel Preparation Before Colonoscopy
A Study of the Efficacy and Safety of Bowklean and Klean-Prep With Dulcolax for the Bowel Preparation Prior Colonoscopy
The primary objective of this study is to demonstrate that investigation medication (Bowklean) is not less effective than the active comparator (Klean-Prep with Dulcolax), with regards to the overall quality of bowel preparation…
- Trial name
- NCT01984008
- Testing
- Picosulfate sodium, magnesium oxide, citric acid
- Where
- Taiwan
- Volunteers
- 631 people, healthy volunteers welcome
- Sponsor
- Universal Integrated Corp.
Bowel Preparation for Colonoscopy
Comparison of Two Methods of Bowel Preparation for Colonoscopy in Hospitalized Patients
Morning-only colonoscopy preparation may improve efficiency by allowing same-day patient preparation and colonoscopy. The aim of the investigators study is to compare the efficacy and tolerability of morning-only Polyethylene…
- Trial name
- NCT01765491
- Testing
- Split-dose polyethylene glycol, Morning-only polyethylene glycol
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Cook County Health
Acute Kidney Injury
Renal Safety of Bowel Preparation With Polyethylene Glycol
This study evaluates the changes of renal function after taking bowel cleansing agent polyethylene glycol for elective colonoscopy.
- Trial name
- NCT02657564
- Testing
- Polyethylene glycol (PEG)
- Where
- Taiwan
- Volunteers
- 1,237 people
- Sponsor
- Evergreen General Hospital, Taiwan
Colonoscopy, Bowel Cleanliness
New Bowel Preparation Scale for Measuring Colon Cleanliness
The purpose of this investigation is validate a new bowel preparation scale and to compare it to existing bowel preparation scales.
- Conditions
- Colonoscopy, Bowel Cleanliness, Bowel Rating Scale
- Trial name
- NCT01635725
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Gastroenterology Services, Ltd.
Indication for Modification of Patient Status (Diagnosis)
Colon Preparation With 2L PEG in Combination With Lubiprostone vs 4L PEG
Colonoscopy is the current standard method for examination of the colon. Bowel cleansing prior to colonoscopy is the essential prerequisite to ensure complete mucosal visualization and lesion identification.(1,2) Suboptimal…
- Trial name
- NCT04138004
- Testing
- polyethylene glycol in combination with lubiprostone, polyethylene glycol alone
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Colorectal Cancer
Clear Liquid vs Liberalized Diet in Preparation for Colonoscopy
Colorectal cancer is the third most common cancer diagnosed in both men and women in the United States. The death rate from this disease, however, has been decreasing over the last 20 years.
- Trial name
- NCT02621658
- Testing
- Clear Liquid Diet, Full Liquid Diet
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- San Antonio Military Medical Center
Bowel Cleanliness
A Study of PICOPREP in Patients Needed to Clean the Bowel Prior to X-ray Examination, Endoscopy or Surgery.
The study serves as a confirmation of safety, tolerance and efficacy of PICOPREP in clinical practice.
- Trial name
- NCT01292109
- Testing
- sodium picosulphate
- Where
- 3 sites in Czechia
- Volunteers
- 252 people
- Sponsor
- Ferring Pharmaceuticals
Colonoscopy Preparation Acceptance
Evaluation of the Impact of Direct Conversation With Patients in the Compliance With the "Split-dose" Regimen Preparation for Colonoscopy Scheduled in the First Part of the Morning
Split-dose cleansing regimens for colonoscopies, independently from the type of laxative used, are now recommended over full (one day)-dose regimens from all the major guidelines.
- Trial name
- NCT02638558
- Testing
- written + oral explanation, written explanation
- Volunteers
- 286 people
- Sponsor
- Valduce Hospital
Colonoscopy
Comparison of Oral Sodium Phosphate and Sennoside A+B Calcium Lavage for Colonoscopy Preparation
The aim of the investigators study is to assess the bowel cleansing effects of two different agents and to compare their safety of application, ease of usage and effects on serum electrolytes.
- Trial name
- NCT01057446
- Sponsor
- Maltepe University
Colonoscopy, Bowel Preparation
Multi-centre Failed Bowel Prep RCT
This is a multi-centre randomized clinical trial comparing the efficacy of two different bowel preparation regimens for patients who have already failed a bowel preparation for colonoscopy.
- Trial name
- B-CLEANR (NCT02976805)
- Testing
- 4L PegLyte + 15 mg bisacodyl, 6L PegLyte + 15 mg bisacodyl
- Where
- 4 sites in Canada
- Volunteers
- 196 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Colon Polyp
The Colon Endoscopic Bubble Scale (CEBuS); Validation Study
Colonoscopy is currently accepted as the gold standard in screening, surveillance and prevention for colorectal cancer (CRC), and therefore, its quality is a major priority.
- Trial name
- CEBuS (NCT04378088)
- Testing
- Validation of CEBuS
- Where
- Portugal
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Colonoscopy
A Safety and Efficacy Comparison of BLI4700 Bowel Preparation Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
The objective of this study is to compare the safety and efficacy of BLI4700 bowel preparation to an FDA-approved bowel preparation as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
- Trial name
- NCT03261960
- Testing
- BLI4700, Magnesium bowel preparation
- Where
- 20 sites in United States
- Volunteers
- 389 people
- Sponsor
- Braintree Laboratories
Split-dose Bowel Preparation, Polyethylene Glycol Solution
Individual Approach for Bowel Preparation Before Colonoscopy
This is a prospective, randomized, single-blind study designed to evaluate the influence of individual approach on bowel preparation quality for colonoscopy.
- Conditions
- Split-dose Bowel Preparation, Polyethylene Glycol Solution, Risk Factors Inadequate Preparation
- Trial name
- NCT01476735
- Testing
- individual preparation for colonoscopy
- Where
- Poland
- Volunteers
- 266 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Colonoscopy (Procedure), 18 Years and Over
Online Nursing Counseling and Colonoscopy Outcomes
This randomized controlled experimental study was conducted in the endoscopy unit of a private hospital between March and June 2023 to evaluate the effect of nurse-delivered counseling on pain, anxiety, and comfort levels in…
- Conditions
- Colonoscopy (Procedure), 18 Years and Over, Literacy, No Communication Difficulties
- Trial name
- NCT07664800
- Testing
- Online Nursing Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanko University
Inflammatory Bowel Diseases
Protocol for Optimizing Colonoscopy Preparation in Patients With Inflammatory Bowel Disease
Clinical trial evaluating efficacy of bowel cleansing solutions in patients with Inflammatory Bowel Disease.
- Trial name
- EII_Prep (NCT04411017)
- Testing
- Endoscopy
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Paz
Colorectal Cancer Screening, Colon Polyps and Adenomas
Artificial Intelligence (AI) Technology May Help Patients to Understand Bowel Preparation Better Before They go for Colonoscopy.This Study Attempts to Leverage AI Chatbot in Counselling Patients to Improve Bowel Cleanliness, Reduce Anxiety as Well as Increase Procedural Satisfaction
Traditional pre-colonoscopy counselling requires significant time from healthcare workers to explain procedures, limiting efficiency and patient turnover.
- Conditions
- Colorectal Cancer Screening, Colon Polyps and Adenomas, Bowel Preparation Quality, Artificial Intelligence (AI)
- Trial name
- NCT06905782
- Testing
- AI chatbot study arm, Traditional counselling study arm
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Bowel Preparation
Efficacy and Safety of Polyethylene Glycol Compared With Sodium Picosulphate for Bowel Preparation Before Colonoscopy
Patients intended for ambulatory colonoscopy will be randomized into 2 groups
- Trial name
- NCT01093274
- Testing
- Sodium Picosulphate, Polyethylene Glycol
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center
Colorectal Cancer, Colonoscopy
Fixed Low-dose Simethicone Combined With Macrogol 4000 (PEG) Reduces Colon Bubble Formation in Colonoscopy
Several randomised studies have shown that the addition of low-dose Simethicone to the bowel preparation was sufficient to reduce the presence of bubbles during colonoscopy.
- Conditions
- Colorectal Cancer, Colonoscopy, Bowel Preparation Solution
- Trial name
- XIMEPEG-RL (NCT06319924)
- Testing
- Simethicone combined with Macrogol 4000 (PEG)
- Where
- 5 sites in France
- Volunteers
- 601 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Bowel Preparation
Accuracy of Trans-abdominal Ultrasound in Evaluating Bowel Preparation Adequacy Before Colonoscopy
Adequate preparation of the large bowel is required for a successful colonoscopy. It has been reported that poor preparation exists in 25% of examinations, which may lengthen overall procedure time, lower adenoma detection rate…
- Trial name
- NCT04087265
- Testing
- Transabdominal ultrasound
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University