Clinical trials: Colonoscopy
Colorectal Disorders
Difficult Colonoscopy and Personality Traits
The cecal intubation time (CIT) refers to the time required for the tip of the colonoscope to reach the cecum from passing through the anus. A prolonged CIT is considered a marker of difficulty in colonoscopy.
- Trial name
- NCT06531226
- Testing
- Fill in personality questionnaires
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Qilu Hospital of Shandong University
Elective Colonoscopy
Efficacy and Safety of mAnnitol in Bowel Preparation During Elective Colonoscopy and Comparison With Moviprep®
The purpose of this dose finding/comparative efficacy study is to first single out the most appropriate dose of mannitol for bowel preparation (phase II) and, subsequently, demonstrate the non-inferiority of the efficacy of…
- Trial name
- SATISFACTION (NCT04759885)
- Testing
- Phase II: NTC015 low dose, Phase II: NTC015 medium dose, Phase II: NTC015 high dose
- Where
- 35 sites in France, Germany and 2 more
- Volunteers
- 886 people
- Sponsor
- NTC srl
Colonoscopy, Oxygenation
Comparison of Oxygenation and Ventilation With a Novel Nasal Mask Versus Standard of Care During Colonoscopy
Nasal continuous positive airway pressure (nCPAP) has been shown to effectively relieve upper airway obstruction in patients with OSA as it creates a pneumatic stent in the hypopharynx that reduces obstruction and allows for…
- Conditions
- Colonoscopy, Oxygenation, Ventilation
- Trial name
- NCT03139448
- Testing
- Oxygen via nasal cannula, Oxygen via SuperNO2VA nasal mask
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Vanderbilt University Medical Center
Gastrointestinal Bleeding
Uninterrupted Clopidogrel Therapy Before Elective Colonoscopy Will Increase the Risk of Post-polypectomy Bleeding
This double-blind, randomized trial aims to evaluate whether uninterrupted anti-platelet therapy (clopidogrel) will increase the risk of bleeding associated with removal of polyp during colonoscopy in patients with coronary…
- Trial name
- NCT01806090
- Testing
- clopidogrel
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Chinese University of Hong Kong
Chronic Diarrhoea, Lymphocytic Colitis
Usefulness of Chromoendoscopy in Diagnosing Microscopic Colitis
The purpose of this study is to determine whether chromoendoscopy using Indigo-Carmine dye spray is useful in diagnosing microscopic colitis among patients undergoing colonoscopy due to chronic watery diarrhea.
- Conditions
- Chronic Diarrhoea, Lymphocytic Colitis, Collagenous Colitis
- Trial name
- NCT01504048
- Testing
- Colonoscopy with Indigo-Carmine Chromoendoscopy
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Karolinska University Hospital
Bowel Preparation for Colonoscopy
Evaluation of the Quality of Bowel Cleansing in a Real Clinical Practice Setting
Publications of the use of bowel cleansers in usual clinical practice are lacking. Patient adherence to investigational products increases in the context of clinical trials.
- Trial name
- CALICOL (NCT02839824)
- Testing
- Bowel preparation
- Where
- Spain
- Volunteers
- 412 people
- Sponsor
- Casen Recordati S.L.
Colonoscopy
Use of Magnetic Imaging to Asses the Efficacy of Cap Assisted Colonoscopy in Reducing Looping and Improving Patient Acceptance for the Colonoscopy Procedure
The aim of this study is to compare the mechanism of loop formation and acceptance of CAC and regular colonoscopy by MEI.
- Trial name
- NCT00365534
- Testing
- MEI
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Colo-rectal Cancer, Gastrointestinal Disease
Diagnostic Usefulness of Different Types of Gastrointestinal Endoscopic Investigations.
The number of endoscopies performed varies greatly between different countries and does not reflect variations in disease incidents.
- Trial name
- NCT04585516
- Testing
- endoscopy
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Region Örebro County
Colonic Polyps
Positioning During Colonoscopy
Colonoscopy is the gold standard investigation in the screening of colorectal neoplasms. The investigators hypothesise that visualisation of the colonic mucosa on extubation may be improved by changing patient position as…
- Trial name
- NCT01254435
- Testing
- Colonoscopy
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Healthy
Bowel Preparation May Lead to a Higher Feasibility of Intestinal Infection
An adequate bowel preparation is essential for a high quality of colonscopy. Nowdays, polyethyleneglyco is considered the most safe drug for bowel preparation, and is widely used around the world.
- Trial name
- NCT05277090
- Testing
- 2L of polyethyleneglycol, inulin, probiotic combination product
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yanqing Li
Colonoscopy, Sedation and Analgesia
Dose-sparing Balanced Propofol Sedation in Colonoscopy
This randomized controlled trial compared two balanced propofol analgosedation strategies in adults undergoing elective colonoscopy.
- Trial name
- NCT07885059
- Testing
- Standard-dose balanced propofol analgosedation, Dose-sparing balanced propofol analgosedation
- Where
- 2 sites in Croatia
- Volunteers
- 76 people
- Sponsor
- University of Split, School of Medicine
Colonoscopy, Incomplete Colonoscopy
Endorail in Long Lasting Colonoscopy
Patients with long lasting colonoscopy are characterized by higher risk of incompletion. Endorail is an accessory for colonoscopy aimed at facilitating progression of the endoscope in the large intestine.
- Trial name
- NCT05626738
- Testing
- ENDORAIL
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 38 people
- Sponsor
- Endostart srl
Colorectal Adenoma
Development and Validation of an Artificial Intelligence-assisted Strategy Selection System for Colonoscopy Cleaning
Patients with poor inadequate bowel preparation need to undergo secondary colonoscopy. but the evaluation of intestinal cleanliness is judged by doctors subjectively.
- Trial name
- NCT04444908
- Where
- China
- Volunteers
- 657 people
- Sponsor
- Renmin Hospital of Wuhan University
Colonoscopy, Pain
Procedural Pain Treatment With Transmucosal Sublingual Fentanyl Tablet in Colonoscopy Patients
Colonoscopy is generally considered an invasive procedure that causes remarkable pain to the patient. The pain associated with the procedure is not caused by the insertion of the scope but from inflating of the colon in order to…
- Trial name
- Abstral (NCT01604187)
- Testing
- Fentanyl
- Where
- Finland
- Volunteers
- 158 people
- Sponsor
- Turku University Hospital
Adenoma Colon
Effect of Water Exchange Plus Acetic Acid Staining on the Detection of Flat Polyps During Colonoscopy
Our previous study (Am. J. Gastroenterol. 2017 04;112(4)) showed that water exchange (WE) colonoscopy was able to increase the detection of flat adenomas as well as overall ADR.
- Trial name
- NCT04464135
- Testing
- acetic acid staining, Water exchange colonoscopy
- Where
- 4 sites in China
- Volunteers
- 300 people
- Sponsor
- Air Force Military Medical University, China
Colonoscopy
Evaluation of Two Different Regimens of Colon Preparations for Advanced Cleaning.
Multicenter, prospective, randomized, checked, open label, with blind evaluation, for compare the intestinal cleansing effectiveness of the regimen full-dose delayed (A) of Clensia vs split regimen (B) of Clensia, in patients…
- Trial name
- ERACLES (NCT05570669)
- Testing
- (Macrogol 4000 52,500 g + Sodium sulphate anhydrous 3,750 g + Simethicone 0,080 g) full dose, (Macrogol 4000 52,500 g + Sodium sulphate anhydrous 3,750 g + Simethicone 0,080 g) split dose
- Where
- 10 sites in Italy
- Volunteers
- 321 people
- Sponsor
- Societa Italiana di Endoscopia Digestiva
Bowel Preparation
Impact of Artificial Intelligence-based Patient Reinforcement on Quality of Colonoscopy
In order to improve bowel preparation for colonoscopy and consequently enhance detection rate of malignant and premalignant findings, a prospective, randomized and controlled three-arm study was developed.
- Trial name
- ARCHES (NCT05041283)
- Testing
- Chatbot, Phone call
- Where
- 3 sites in Germany
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Colorectal Cancer, Colon Adenoma
A Randomized Prospective Trial Comparing Polyethylene Glycol and Sodium Picosulphate With Magnesium Citrate
Adequate bowel cleansing is important for a completeness of colonoscopy and detection of colon polyps. Inadequate bowel preparation leads to longer duration of colonoscopy and obscured mucosal visualization resulting in missed…
- Trial name
- NCT01778192
- Testing
- Polyethylene glycol, Sodium picosulphate with magnesium citrate
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Korea University Anam Hospital
C-difficile
Reduction of C-Difficile Infection Using Stool Transplant
Clostridium-difficile (C-difficile) is a gram positive anaerobic spore-forming bacterium that can lead to severe diarrhea and pseudomembranous colitis.
- Trial name
- FMT (NCT02112279)
- Testing
- Donor microbiota applied via colonoscopy.
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Providence Holy Cross Medical Center
Adenoma
The Effect of Segmental Re-examination of Colon for Adenoma Detection in Colonoscopy
The aim of this study was to determine whether segmental re-examination of the each segment (right colon, mid-colon, and left colon) could increase the proximal adenoma detection rate (ADR) and to evaluate the time-effectiveness…
- Trial name
- NCT03268200
- Testing
- segmental reexamination
- Where
- South Korea
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea