Clinical trials: Colonization
Pre-Eclampsia, Asymptomatic Bacteriuria
Prevalence of Asymptomatic Bacteriuria Among Pregnant Women With Pre-eclampsia in Women Health Hospital Assiut University
Pre-eclampsia is a hypertensive disorder of pregnancy that can lead to significant health complications for both the mother and the fetus.
- Trial name
- NCT07866196
- Volunteers
- 129 people
- Sponsor
- Assiut University
Pneumonia, Bacterial Pneumonia
Multiplex Polymerase Chain Reaction in Postoperative Pneumonia After Thoracic Surgery
Background: In thoracic surgery, postoperative pneumonia (POP) is the leading cause of postoperative morbidity and mortality. The clinical diagnosis of POP is difficult and conventional microbiological diagnostic tests perform…
- Trial name
- POP-PCR (NCT03752320)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Methicillin-resistant Staphylococcus Aureus Infection
Incidence and Relationship of Positive Preoperative Methicillin Resistant Staphylococcus Aureus (MRSA) Screens and Post-operative Infections
The purpose of this study is to evaluate the prevalence of pre-surgical patients who are MRSA carriers. From an evidence-based practice perspective, findings from this study can be considered in the evaluation of the hospital SOP…
- Trial name
- MRSA (NCT01028105)
- Testing
- Preoperative MRSA screening
- Where
- 2 sites in United States
- Volunteers
- 975 people
- Sponsor
- Inova Health Care Services
Hemodialysis
Development of a Probiotic Strategy to Prevent or Eliminate Nasal Colonization With S. Aureus
The goal of this study is characterize the changes in bacterial diversity of the nares of hemodialysis patients. Another goal is to determine when hemodialysis patients become colonized with the bacteria Staphylococcus aureus, as…
- Trial name
- NCT00977496
- Testing
- Nasal Swab
- Sponsor
- Tufts Medical Center
Pancreatic Cancer, Pancreatic Disease
Retrospective Study on Microbial Diversity in Paraffin Tissue of Pancreatic Diseases
The great harm of pancreatic diseases and the unknown etiology and pathogenesis make it difficult to intervene in most early cases in time.
- Conditions
- Pancreatic Cancer, Pancreatic Disease, Microbial Colonization
- Trial name
- NCT05193162
- Testing
- No any intervention
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Ruijin Hospital
Microbial Colonization
Evaluation of Bacterial Flora Among Operation Theatre Staff at a Tertiary Care Hospital
Health care associated infection (HCAI) is a serious health hazard as it leads to increased morbidity and mortality of patients, length of hospital stay and costs associated with increased hospital stay.
- Trial name
- NCT04089683
- Testing
- Swab stick
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- Kamineni Academy of Medical Sciences and Research Centre
Leg Ulcer
Topical Sevoflurane for Treatment of Chronic Leg Ulcers
Patients with painful non-healing leg ulcer will be enrolled in the clinical single-blinded randomized study. The active treatment group will have sevoflurane applied at approximately 1 ml/cm2 at the start of wound treatment, the…
- Trial name
- NCT05303805
- Testing
- Sevoflurane, Cyteal
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Charles University, Czech Republic
Surgical Site Infection
Time of Permanence of Dressing Following Breast Reconstruction
This randomized clinical trial was designed to assess the influence of time of dressing after breast reconstruction procedures on surgical site infections rates and skin colonization.
- Trial name
- NCT01148823
- Testing
- Incisions covered for 1 day, Incisions covered for 6 days
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Daniela Francescato Veiga
Hereditary Hemorrhagic Telangiectasia, Epistaxis
Treatment of Nasal Staphylococcus Aureus Colonization in Patients With HHT
Compare the frequency of epistaxis and quality of life related to nasal bleeding in patients with HHT colonized with sataphylococo before and after being treated with mupirocin ointment.
- Trial name
- NCT02963129
- Testing
- Mupirocin
- Where
- 2 sites in Argentina
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Acute Otitis Media (AOM)
Safety and Efficacy of wSp Vaccine in Young Children
The goal of this clinical trial is to evaluate whether the wSp vaccine can prevent nasopharyngeal colonization by pneumococcal bacteria in healthy young children who have received routine PCV15 or PCV20 vaccination.
- Trial name
- wSp005 (NCT07216430)
- Testing
- wSp vaccine, Saline (0.9% NaCl)
- Where
- 7 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Serum Life Science Europe GmbH
Interstitial Cystitis, Bladder Pain Syndrome
The Female Microbiome in Patients Undergoing Bladder Instillation Therapy
The underlying pathophysiology for BPS/IC is currently an active area of research. There is speculation that there may be alteration in the bladder and vaginal microbiome that contributes to the symptomatology of BPS/IC, however…
- Conditions
- Interstitial Cystitis, Bladder Pain Syndrome, Microbial Colonization
- Trial name
- NCT05414305
- Testing
- Heparin & Alkalinized Lidocaine Bladder Instillation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Walter Reed National Military Medical Center
Carbapenem-Resistant Enterobacteriaceae Infection
Fecal Microbiota Transplantation for Carbapenem Resistant Enterobacteriaceae
Open-label, single center, prospective interventional non-comparative study for CRE carriers.
- Trial name
- NCT04790565
- Testing
- FMT
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Rambam Health Care Campus
MRSA Colonization
A Novel Approach to Methicillin-resistant Staphylococcus Aureus (MRSA) Screening of Colonized Patients
Methicillin-resistant Staphylococcus aureus (MRSA) is endemic in hospital settings. Colonization with MRSA puts patients at increased risk for invasive infections, and MRSA infections have been associated with high costs and…
- Trial name
- NCT01234831
- Testing
- nucleic acid amplification of nasal swab; nasal swab culture, Nasal swab culture
- Where
- United States
- Volunteers
- 463 people
- Sponsor
- Massachusetts General Hospital
Microbial Colonization, Metabolic Syndrome
Effects of Pulse Consumption, Gut Microbiome, and Appetite in Healthy Participants
The purpose of the study is to investigate the effects of pulse consumption versus no pulse consumption on the gut microbiome, meal satiety, and short-chain fatty acid metabolomics.
- Trial name
- PULSE (NCT07043712)
- Testing
- High pulse consumption
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Nasopharyngeal Carcinoma, Radiation-induced Oral Mucositis
Bacterial Decolonization to Prevent Radiation-induced Oral Mucositis
The purpose of this study is to determine whether bacterial decolonization of the nares prior to treatment with radiotherapy (RT) for patients with nasopharyngeal carcinoma, can prevent high-grade radiation-induced oral mucositis…
- Conditions
- Nasopharyngeal Carcinoma, Radiation-induced Oral Mucositis, Bacterial Colonization, Quality of Life
- Trial name
- NCT05893810
- Testing
- Mupirocin Ointment
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Bronchopulmonary Dysplasia, Extreme Prematurity
Relationship Between Fungal Colonization and Severe Bronchopulmonary Dysplasia
The aim of this study is to determine if fungal colonization is associated to severe bronchopulmonary dysplasia in premature infants less than 29 weeks of gestation, and to determine if an association exists between fungal…
- Conditions
- Bronchopulmonary Dysplasia, Extreme Prematurity, Fungal Infection
- Trial name
- FunDyP (NCT05152875)
- Testing
- biological
- Where
- France
- Volunteers
- 153 people
- Sponsor
- Centre Hospitalier Sud Francilien
Nutrition, Healthy, Adolescent Behavior
Effect of Nutritional Habits on Oral Microbiota in Adolescents
The aim of this study is to examine the relationship between oral microbiota and eating habits, sleep quality and hedonic hunger in adolescents.
- Conditions
- Nutrition, Healthy, Adolescent Behavior, Microbial Colonization
- Trial name
- NCT06425328
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Drug Resistance, Multiple, Travel Medicine
The Effect of Hand Hygiene on Colonization Rates With Multidrug Resistant Enteric Pathogens in Travellers
Travelling to tropical and subtropical countries is a known risk factor for becoming colonized with extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae.
- Trial name
- NCT03306407
- Testing
- Improved hand hygiene
- Where
- 2 sites in Switzerland
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Christoph Hatz
Cystic Fibrosis
Dissection of Staphylococcus Aureus Infection From Colonization in Cystic Fibrosis Patients
Staphylococcus aureus is not only one of the first pathogens infecting the airways of cystic fibrosis (CF) patients, but also a highly prevalent microorganism (>60% of all CF patients; European and American CF registries; (4,25)…
- Trial name
- StaphCI (NCT00669760)
- Testing
- non-interventional study
- Where
- 17 sites in Austria, Germany
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Minimal Flow Anesthesia, General Anaesthesia
Minimal Flow Anesthesia and Infection Risk
This study is being done to find out if the heat and moisture that build up during minimal flow anesthesia can lead to the growth of germs (microorganisms) inside the anesthesia equipment.
- Conditions
- Minimal Flow Anesthesia, General Anaesthesia, Inhalation Anesthesia, Infection Risk
- Trial name
- NCT07092046
- Testing
- Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent