Clinical trials: Colon Polyps and Adenomas
Colon Polyp, Adenoma Colon
Underwater Endoscopic Mucosal Resection
The global aim of this multi-centric study is to assess the learning curve of U-EMR by an endoscopist skilled in C-EMR aiming to assess the application in real world and check the rate of complete EMR and adverse events related…
- Trial name
- NCT06073561
- Testing
- learning curve of Underwater mucosectomy
- Where
- Portugal
- Volunteers
- 90 people
- Sponsor
- Instituto Portugues Oncologia de Lisboa Francisco Gentil
Colonic Polyp, Adenoma Colon
Accuracy of CADx System for White Light Colonic Polyp Characterization
The endoscopist performances in the optical diagnosis (OD) of colonic polyps with the available technologies vary widely across centers and across endoscopists.
- Trial name
- GIC (NCT05492656)
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Valduce Hospital
Sessile Serrated Adenoma, Colorectal Polyp
Assessing the Agreement Between Endoscopic and Histopathological Diagnosis of Colorectal Sessile Serrated Lesions.
The goal of this observational study was to assess the degree of agreement between the endoscopic and anatomopathological diagnosis of sessile serrated colorectal lesions in adult patients undergoing colonoscopy in Hospital…
- Conditions
- Sessile Serrated Adenoma, Colorectal Polyp, Adenoma Colon, Colorectal Cancer
- Trial name
- NCT06173297
- Where
- Brazil
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- Hospital Sirio-Libanes
Right Colon Adenoma Miss Rate, Right Colon Hyperplastic Polyp Miss Rate
Multicenter Evaluation of Right Colon Polyp Miss Rates Using Water Exchange Versus CO2 Insufflation
A prospective multicenter randomized controlled trial (RCT) comparing water exchange (WE) colonoscopy and carbon dioxide (CO2) insufflation in terms of right colon combined adenoma miss rate (AMR) and hyperplastic polyp miss rate…
- Trial name
- NCT04124393
- Testing
- Colon Polypectomy
- Where
- Taiwan
- Volunteers
- 386 people
- Sponsor
- Evergreen General Hospital, Taiwan
Colorectal Cancer, Diagnoses Disease
The Argentina Brief Colonoscopy Difficulty Score (ABCD)
Colonoscopy completion by caecal intubation seldom represents a significant effort for the endoscopist. In this situation, additional techniques are necessary to achieve this goal: patients' manual abdominal compression, postural…
- Conditions
- Colorectal Cancer, Diagnoses Disease, Polyp of Colon, Adenoma Colon
- Trial name
- ABCD (NCT05422820)
- Testing
- Diagnostic high-definition white-light (HDWL) colonoscopy
- Where
- Argentina
- Volunteers
- 5,000 people
- Sponsor
- Institute of Gastroenterology and Advance Endoscopy
Colonic Neoplasms, Colorectal Cancer
Molecular and Histological Characteristics of Serrated Lesions of the Colon
Different subtypes of serrated lesions have been recently described. Among them, both sessile serrated polyp/adenoma (SSP/A) and traditional serrated adenoma (TSA) could have malignant potential through the serrated pathway or…
- Conditions
- Colonic Neoplasms, Colorectal Cancer, Sessile Serrated Adenoma, Polyp of Colon
- Trial name
- SERRACOLON (NCT03089268)
- Testing
- Colonoscopy, Polypectomy or biopsy, Molecular analysis
- Where
- Spain
- Volunteers
- 700 people
- Sponsor
- Hospital Universitario La Fe
Adenoma Colon, Serrated Polyp
Cold EMR Vs Standard EMR for the Treatment of Large Nonpedunculated Homogeneous Colorectal Lesions
This study compares the effectiveness in complete resection (absence of recurrence at 6 months) the two different techniques for performing endoscopic mucosal resection (EMR) of nonpedunculated homogeneous colorectal lesions >20mm
- Conditions
- Adenoma Colon, Serrated Polyp, Serrated Adenoma, Colorectal Neoplasms
- Trial name
- NCT04418843
- Testing
- Standard Endoscopic Mucosal Resection, Cold Snare Endoscopic Mucosal Resection
- Where
- Spain
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Oscar Nogales
Polyp Colorectal, Adenoma Colon
AI Colorectal Polyp Detection
This study is intended to demonstrate the superiority of colorectal polyp detection using computer-assisted colonoscopy compared to conventional colonoscopy.
- Trial name
- NCT04979962
- Testing
- EW10-EC02 (Endoscopy Support Program)
- Where
- 10 sites in United States
- Volunteers
- 1,162 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.
Polyp of Colon, Adenoma Colon
Artificial Intelligence in Colonic Polyp Detection
A randomized, controlled study investigating the potential benefits of artificial intelligence (AI) in the detection of colonic polyps during outpatient colonoscopy.
- Conditions
- Polyp of Colon, Adenoma Colon, Gastrointestinal Neoplasms
- Trial name
- NCT05178095
- Testing
- Artificial intelligence, No Artificial Intelligence
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Sahlgrenska University Hospital
Colon Cancer, Colon Polyp
Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)
The study will compare the use of cold snare, hot snare, cold EMR, and hot EMR for polyp resection. Although previous studies have compared two of the potential resection methods, no previous study has evaluated all four of the…
- Conditions
- Colon Cancer, Colon Polyp, Colon Adenoma
- Trial name
- NCT03462706
- Testing
- Cold Snare, Hot Snare, Cold EMR
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colonoscopy, Histology
In Vivo Computer-aided Prediction of Polyp Histology on White Light Colonoscopy
Our group, prior to the present study, developed a handcrafted predictive model based on the extraction of surface patterns (textons) with a diagnostic accuracy of over 90%24.
- Conditions
- Colonoscopy, Histology, Computer-aided Diagnosis, Artificial Intelligence
- Trial name
- NCT03775811
- Testing
- AUTOMATED POLYP CLASSIFICATION
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Clinic of Barcelona
Colonic Polyps, Colon Neoplasms
Precision of Optical Diagnosis in Polyps Between 5-15 mm and Its Implications on Surveillance. A Prospective, Multicenter Study.
This study evaluates the ability of endoscopists to perform a complete optical diagnosis of colorectal polyps between 5 and 15 mm, and the impact of the only endoscopic diagnosis on the follow-up program for those patients.
- Conditions
- Colonic Polyps, Colon Neoplasms, Colon Cancer, Serrated Adenoma
- Trial name
- POPS (NCT04232176)
- Where
- Spain
- Volunteers
- 545 people
- Sponsor
- University Hospital Virgen de las Nieves
Colon Adenoma, Colon Polyp
Artificial Intelligence-assisted Colonoscopy on Detection of Missed Proximal Lesions
This is a prospective multi-center randomized study is to determine whether the use of artificial intelligence (AI)-assistance could reduce the miss rates of polyps and adenomas in the proximal colon during tandem examination
- Trial name
- NCT04294355
- Testing
- Artificial intelligence-Assisted colonoscopy, Conventional colonoscopy
- Where
- 3 sites in China, Singapore and 1 more
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colorectal Neoplasms, Intestinal Neoplasms
Usefulness of GI-GENIUS in FIT-based Colorectal Cancer Screening Program.
Deep learning technology has an increasing role in medical image applications and, recently, an artificial intelligence device has been developed and commercialized by Medtronic for identification of polyps during colonoscopy…
- Conditions
- Colorectal Neoplasms, Intestinal Neoplasms, Gastrointestinal Neoplasms, Colonic Polyp
- Trial name
- CADILLAC (NCT04673136)
- Testing
- GI-GENIUS Medtronic, Colonoscopy
- Where
- 6 sites in Spain
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Asociación Española de Gastroenterología
Polyp of Colon, Endoscopic Mucosal Resection
EndoRotor® Endoscopic Mucosal Resection System for the Colon
The EndoRotor® is intended for use (USA labeling) in endoscopic procedures by a trained gastroenterologist to resect and remove tissue, not intended for biopsy, of the gastrointestinal (GI) system including post-endoscopic…
- Conditions
- Polyp of Colon, Endoscopic Mucosal Resection, Recurrent Colon Adenoma
- Trial name
- NCT04203667
- Testing
- EndoRotor Resection
- Where
- 11 sites in United States, France and 2 more
- Volunteers
- 66 people
- Sponsor
- Interscope, Inc.
Colon Polyp, Colon Neoplasm
A Clinical Study To Measure The Effect Of Use Of Artificial Intelligence (AI) Enabled Computer Aided Detection (CADe) Assistance Software In Detecting Colon Polyps During Standard Colonoscopy Procedures
EndoVigilant software device augments existing colonoscopy procedure video in real-time by highlighting colon polyps and mucosal abnormalities.
- Conditions
- Colon Polyp, Colon Neoplasm, Colon Adenoma
- Trial name
- ColonCADe (NCT04555135)
- Testing
- EndoVigilant Software
- Where
- 4 sites in United States
- Volunteers
- 769 people
- Sponsor
- EndoVigilant Inc
Colorectal Neoplasms, Colon Polyp
Computer-aided Detection During Screening Colonoscopy (Experts)
Evaluation of the colonic mucosa with a high definition colonoscope (EPKi7010 video processor). The endoscopy images will be seen on a 27inch, flat-panel, high-definition LCD monitor (Radiance™ ultraSC-WU27-G1520 model) only by…
- Conditions
- Colorectal Neoplasms, Colon Polyp, Colon Adenoma
- Trial name
- NCT04915833
- Testing
- Standard high-definition colonoscopy, Colonoscopy with real-time AI assisted automated polyp detection
- Where
- Ecuador
- Volunteers
- 209 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Colo-rectal Cancer, Cancer Colon
AI-EMERGE: Development and Validation of a Multi-analyte, Blood-based Colorectal Cancer Screening Test
Freenome is using a type of artificial intelligence, called machine learning, to identify patterns of cell-free biomarkers in blood to detect cancer early.
- Conditions
- Colo-rectal Cancer, Cancer Colon, Cancer, Rectum, Neoplasms,Colorectal
- Trial name
- NCT03688906
- Where
- 30 sites in United States, Canada
- Volunteers
- 3,275 people, healthy volunteers welcome
- Sponsor
- Freenome Holdings Inc.
Colon Polyp, Colorectal Adenoma
9 Minutes for Tandem Colonoscopy Withdrawal
A mean withdrawal time of at least 6 minutes has been considered to be one of the critical quality criterions of colonoscopy. Recently, our group completed a multicenter randomized controlled trial, which proved that prolonging…
- Trial name
- NCT04797065
- Testing
- 6-minute then 9-minute withdrawal, 9-minute then 6-minute withdrawal
- Where
- China
- Volunteers
- 733 people
- Sponsor
- Changhai Hospital
Colon Polyp, Colorectal Adenoma
a Low-residue Diet for Bowel Preparation
Previous researches demonstrated that a prepackaged low-residue diet (LRD) could achieve better bowel preparation quality compared with a self-prepared LRD.
- Trial name
- NCT03943758
- Testing
- Prepackaged Low-residue diet, Self-prepared Low-residue diet
- Where
- China
- Volunteers
- 589 people
- Sponsor
- Changhai Hospital