Clinical trials: Colon Polyp
Colonic Adenoma, Colonic Polyp
Endocuff-assisted Colonoscopy vs Standard Colonoscopy on Adenoma Detection Rate
This is a prospective study comparing endocuff-assisted colonoscopy to standard colonoscopy. The goal of this study is to evaluate the interest of second-generation Endocuff Vision (ECV) to improve Adenoma detection rate and / or…
- Conditions
- Colonic Adenoma, Colonic Polyp, Colonoscopy
- Trial name
- Cuff-Bercy (NCT03344055)
- Testing
- Endocuff Vision (ECV) second generation
- Where
- France
- Volunteers
- 2,059 people
- Sponsor
- Société Française d'Endoscopie Digestive
Adenoma Colon, Polyp of Colon
Computer-aided Detection of Colorectal Polyps
In this observational pilot study, we assess the diagnostic performance of an artificial intelligence sytem for automated detection of colorectal polyps.
- Trial name
- NCT04359355
- Testing
- Artificial Intelligence System for Detection of colorectal polyps
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Colorectal Polyp, Inflammation
Impact of Dietary Intervention on Inflammation and Microbiome Composition Post-Colonoscopy
This study aims to investigate the impact of various healthy diets, specifically a modified plant-based Mediterranean diet, on the gut microbiome and overall well-being post-colonoscopy.
- Conditions
- Colorectal Polyp, Inflammation, Dietary Intervention, Microbiota
- Trial name
- NCT06603519
- Testing
- Modified Plant-Based Mediterranean Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Adenoma, Colo-rectal Cancer
Clinical Value of G-EYE Colonoscopy in Daily Practice for Adenoma Detection and Time for Polyp Removal
Colonoscopy parameters will be compared before the introduction of the G-EYE endoscope and after the introduction of the G-EYE endoscope
- Trial name
- NCT04767971
- Testing
- Standard Colonoscopy, G-EYE Colonoscopy
- Where
- Germany
- Volunteers
- 2,795 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Ulcerative Colitis, Colorectal Cancer
Objective Perfusion Rate Assessment by Near-infrared Fluorescence in Ileal Pouch Formation and Ileal-pouch-anal Anastomosis
In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at three time points during ileal pouch…
- Conditions
- Ulcerative Colitis, Colorectal Cancer, Crohn Disease, Familial Adenomatous Polyposis
- Trial name
- NCT04695964
- Testing
- ICG-NIRF Imaging plus ingress and egress analysis
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Colonic Dysplasia, Adenomatous Polyps
Study of Performance of Confocal Endomicroscope With Fluorescein Imaging Agent in the Colon
The overall aim of this research project is to evaluate the imaging performance of a confocal endomicroscope. Fluorescein, an FDA-approved topical fluorescent dye, will be used to provide topical mucosal contrast.
- Conditions
- Colonic Dysplasia, Adenomatous Polyps, Irritable Bowel Disease
- Trial name
- NCT03220711
- Testing
- confocal endomicroscope, Fluorescein
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Michigan
Polyp of Large Intestine
EFficacy of Prophylactic Clip Application in Decrease of Immediate Postpolypectomy Bleeding and Delayed Postpolypectomy Bleeding After Colonoscopic Removal for a Large Pedunculated Polyps
The aim of this study is to evaluate the efficacy of prophylactic clip application after colonoscopic removal for a large pedunculated polyp (> 1cm) in preventing immediate postpolypectomy bleeding (IPPB) and delayed…
- Trial name
- NCT01437631
- Testing
- prophylactic clip application
- Where
- South Korea
- Volunteers
- 137 people
- Sponsor
- Asan Medical Center
Colonic Polyp
Blue Light Imaging (BLI) for Optical Diagnosis of Colorectal Polyps
Several imaging technologies have been developed in order to enable the endoscopists to differentiate neoplastic from non-neoplastic lesions.
- Trial name
- BIRD (NCT03746171)
- Testing
- Colonic polyp characterization by BLI
- Where
- Italy
- Volunteers
- 324 people
- Sponsor
- Valduce Hospital
Familial Adenomatous Polyposis
Small Bowel Endoscopic Evaluation in Familial Adenomatous Polyposis (FAP)
Background and study aim The relative risks of duodenal adenocarcinoma and ampullary carcinoma in Familial Adenomatous Polyposis (FAP) have been estimated 100 to 330 times higher than in general population.
- Trial name
- NCT02656134
- Testing
- Duodenoscopy and enteroscopy, Molecular analysis.
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- University of Sao Paulo
Familial Adenomatous Polyposis
The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study
Familial adenomatous polyposis (FAP) leads to adenomas and eventual adenocarcinomas in colon and less frequently, duodenum. Chemopreventive strategies have been studied in FAP patients to delay the development of adenomas and…
- Trial name
- NCT01725490
- Testing
- Metformin
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Yonsei University
Inflammatory Bowel Diseases, Dysplasia Colon
OPtical Diagnosis Training to Improve Dysplasia Characterisation in IBD
People with inflammatory bowel diseases (IBD) can be at higher risk of developing abnormal areas in their bowel. These abnormal areas can be due to active inflammation, healed inflammation, polyps or pre-cancerous changes…
- Conditions
- Inflammatory Bowel Diseases, Dysplasia Colon, Dysplasia, Crohn Disease-Associated, Polyp of Colon
- Trial name
- OPTIC-IBD (NCT04924543)
- Testing
- Online self-learning training module, Refresher training
- Where
- 5 sites in Canada, Italy and 1 more
- Volunteers
- 182 people
- Sponsor
- University of Birmingham
Colorectal Cancer, Adenomatous Polyps
Multi-omics Study for Early Detection of Colorectal Cancer (MOED-CRC)
The primary objective of the study is to screen multi-omics markers in blood samples and construct a prediction model for CRC based on liquid biopsy, and we will further optimize the prediction model by validating its clinical…
- Conditions
- Colorectal Cancer, Adenomatous Polyps, Adenoma, Advanced Adenoma
- Trial name
- NCT06220617
- Where
- 6 sites in China
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Bowel Obstruction, Bowel Ischemia
Perfusion Rate Assessment by Near-infrared Fluorescence in Gastrointestinal Anastomoses
In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at two to three time points during procedures of…
- Conditions
- Bowel Obstruction, Bowel Ischemia, Diverticulitis, Abnormality of the Gastrointestinal Tract
- Trial name
- NCT04709445
- Testing
- ICG-NIRF Imaging plus ingress and egress analysis
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Colonic Polyp, Colonic Adenoma
Detection Of Colonic Polyps In India: Diagnostic Colonoscopy
Colorectal carcinoma (CRC) is the third most common cancer in male and female worldwide. In India, it is the fourth most common cause of cancer in males and third most common cancer in female.
- Conditions
- Colonic Polyp, Colonic Adenoma, Colonic Neoplasms
- Trial name
- DoCPI (NCT04512729)
- Testing
- Colonoscopy
- Where
- India
- Volunteers
- 4,000 people
- Sponsor
- Asian Institute of Gastroenterology, India
Polyp of Colon
Impact of Artificial Intelligence (AI) on Adenoma Detection During Colonoscopy in FIT+ Patients.
The Italian screening program invites the resident population aged 50-74 for Fecal Immunochemical Test (FIT) every 2 years. Subjects who test positive are referred for colonoscopy.
- Trial name
- AIFIT (NCT04691401)
- Testing
- Artificial Intelligence System (CAD EYE, Fujifilm Co.)
- Where
- Italy
- Volunteers
- 750 people
- Sponsor
- Valduce Hospital
Colon Adenoma, Colorectal Carcinoma
NBI Versus White Light Endoscopy for Optical Characterization of Neoplastic Polyps in the Colorectum
Adenomas, serrated adenomas and hyperplastic polyps are polypoid lesion in the colorectum. At the present moment, all polyps should be resected endoscopically, although only adenomas and serrated adenomas, but not hyperplastic…
- Conditions
- Colon Adenoma, Colorectal Carcinoma, Hyperplastic Polyp, Serrated Adenoma
- Trial name
- ADOPTION II (NCT03679429)
- Testing
- NBI Function
- Where
- 3 sites in Germany
- Volunteers
- 370 people
- Sponsor
- Technical University of Munich
Colorectal Neoplasms, Colorectal Neoplasms Malignant
Robotic Right Hemicolectomy Versus Laparoscopic Right Hemicolectomy
Robotic right hemicolectomy with intra-corporeal anastomosis may have better short-term recovery outcomes and decreased incidence of incisional hernia when compared to the laparoscopic actual standard of care, for similar safety…
- Conditions
- Colorectal Neoplasms, Colorectal Neoplasms Malignant, Colorectal Neoplasms, Benign, Colorectal Cancer
- Trial name
- PRORHEM (NCT06067620)
- Testing
- Robotic right hemicolectomy, Laparoscopic right hemicolectomy
- Volunteers
- 70 people
- Sponsor
- Jeremy Meyer
Adenoma Colon
White Light vs Narrow Band Imagingin the Diagnosis of Right Sided Colonic Polyps in Asymptomatic Subjects Undergoing Screening Colonoscopy
A randomized controlled crossover study to determine if narrow band imaging or white light endoscopy is superior in detecting right colonic polyps in average risk subjects undergoing screening colonoscopy
- Trial name
- WLEvsB-NBI (NCT05935124)
- Testing
- WLE first, then B-NBI
- Where
- Australia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Western Sydney Local Health District
Colon Adenoma, Colonoscopy
Adenoma Detection Rate in Water and Air Colonoscopy Using Computer-aided System
Water exchange (WE) is an effective insertion method to minimize insertion discomfort and maximize ADR. It is characterized by infusing water to guide insertion in an airless lumen with suctioning of infused water during…
- Trial name
- NCT05448300
- Testing
- Colonoscopy with water exchange or air insufflation methods
- Where
- 2 sites in United States, Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Colon Polyps
A Prospective Trial of an Endoscopic Quality Improvement Project
Randomized prospective multi-site validation study.
- Trial name
- Equip 2 (NCT02325635)
- Testing
- Educational Training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic