Clinical trials: Colon Polyp
Hypoxia, Gastric Polyp
The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway in Gastrointestinal Endoscopy Procedure
Hypoxia represents the prevailing adverse occurrence during the sedation of patients undergoing gastrointestinal endoscopy with propofol.
- Conditions
- Hypoxia, Gastric Polyp, Colon Cancer, Esophageal Cancer
- Trial name
- NCT06081647
- Testing
- the COMBO Endoscopy Oropharyngeal Airway, Regular Nasal Cannula
- Where
- 10 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Hypoxia, Esophageal Cancer
Combination COMBO Endoscopy Oropharyngeal Airway With High-Flow Nasal Cannula Oxygenation in Sedated Gastrointestinal Endoscopy for Obese Patients
Hypoxia is the most common adverse event during propofol sedation for gastrointestinal endoscopy, particularly in obese patients.
- Conditions
- Hypoxia, Esophageal Cancer, Gastric Cancer, Polyp of Colon
- Trial name
- NCT06812403
- Testing
- the COMBO Endoscopy Oropharyngeal Airway with High-Flow Nasal Cannula Oxygenation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhejiang University
Artificial Intelligence (AI), Colonoscopy Education
Artificial Intelligence-assisted Colonoscopy, Tandem Study
The goal of this clinical trial is to evaluate effect of artifial intelligent (AI) system, Endoscopy as AI-powered Device (ENAD) on adenoma miss rate from colonoscopy underwent by trainee endoscopist.
- Conditions
- Artificial Intelligence (AI), Colonoscopy Education, Adenoma Colon Polyp
- Trial name
- NCT07023471
- Testing
- Group A (Trainee --> expert), Group B (Trainee +AI --> expert), Group C (Trainee --> expert + AI)
- Where
- Thailand
- Volunteers
- 364 people
- Sponsor
- Mahidol University
Polyp of Colon
Prevention of Post-Polypectomy Colorectal Bleeding by Clips in Patients on Anticoagulants
This observational study aims to retrospectively determine if clips can prevent post-polypectomy bleeding in adults who have received restarted anticoagulants after a colorectal polypectomy, using a large, single-center patient…
- Trial name
- PiCAnt (NCT07007598)
- Testing
- Hemostatic clip
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- Helios Kliniken Schwerin
Colon Polyp, Colon Adenoma
Prospective Evalulation of Artificial Intelligence-assisted Monitoring of Effective Withdrawal Time Versus Standard Withdrawal Time on Adenoma Detected Per Colonoscopy
The goal of this observational study is to assess the correlation between the artificial intelligence (AI) derived effective withdrawal time (EWT) during colonoscopy and endoscopists' adenoma per colonoscopy (APC), polyp per…
- Conditions
- Colon Polyp, Colon Adenoma, Artificial Intelligence
- Trial name
- NCT06345105
- Testing
- Endoscreener QC
- Where
- Hong Kong
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Hypoxia, Gastric Cancer
Nasal Mask Kit in Gastrointestinal Endoscopy
Hypoxia is the most common adverse event in gastrointestinal endoscopes sedated with propofol. The nasal mask oxygen kit has good sealing to ensure an adequate oxygen supply and is convenient and economical.The aim of this…
- Conditions
- Hypoxia, Gastric Cancer, Gastric Polyp, Colon Polyp
- Trial name
- NASO (NCT05405530)
- Testing
- nasal mask oxygen kit, regular nasal cannula
- Where
- 3 sites in China
- Volunteers
- 1,204 people
- Sponsor
- RenJi Hospital
Colorectal Cancer, Adenomas Colon
CRC Detection Reliable Assessment With Blood
The CRC DRAW study will assess the sensitivity and specificity of the blood-based, Next-Gen CRC Screening Test for the detection of CRC.
- Conditions
- Colorectal Cancer, Adenomas Colon, Colon Cancer, Rectal Cancer
- Trial name
- CRC-DRAW (NCT05551052)
- Testing
- Next-Gen CRC Screening Test
- Where
- 3 sites in United States
- Volunteers
- 196 people
- Sponsor
- New Day Diagnostics
Cancer Diagnosis, Liver Cancer, Adult
Raman Spectroscopy-Based Deep Learning Model for Early Pan-Cancer Early Diagnosis
The goal of this observational study is to explore whether a Raman-based, deep learning-assisted approach can be used to develop an effective method for early pan-cancer screening.
- Conditions
- Cancer Diagnosis, Liver Cancer, Adult, Cancer Screening, Colorectal Cancer (CRC)
- Trial name
- NCT06822413
- Testing
- No Interventions
- Where
- 4 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Adenoma Colon Polyp
Artificial Intelligence-assisted System in Colonoscopy
In recent years, computer-aided diagnosis system based on artificial intelligence (AI) has been used in colorectal polyp detection.
- Trial name
- NCT06406062
- Testing
- ANDOANGEL
- Where
- China
- Volunteers
- 7,500 people
- Sponsor
- Renmin Hospital of Wuhan University
Colon Preparation, Polyps Colorectal
Efficacy And Tolerability Of Asymmetric Split Regimen For Bowel Preparation
The investigators aimed to compare the efficacy for bowel cleansing of a split-dose regimen with a low morning dose of PEG solution (Asymmetric; 25% of the dose is given on the day of the procedure and 75% of the dose is given on…
- Trial name
- NCT06916689
- Testing
- 1L PEG-Asc
- Where
- Italy
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- ASST Rhodense
Colonic Neoplasms, Colonic Adenocarcinoma
Assessing the Additional Neoplasia Yield of Computer-aided Colonoscopy in a Screening Setting
Even if colonoscopy is considered the reference standard for the detection of colonic neoplasia, polyps are still missed. The risk of early post-colonoscopy cancer appeared to be independently predicted by a relatively low…
- Conditions
- Colonic Neoplasms, Colonic Adenocarcinoma, Polyps of Colon, Rectal Neoplasms
- Trial name
- GENIAL-CO (NCT04441580)
- Testing
- CADe colonoscopy using GI Genius device
- Where
- Italy
- Volunteers
- 900 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Colo-rectal Cancer, Colon Polyp
Optimizing Timing of Follow-up Colonoscopy
Overall Objective: To optimize timing of surveillance colonoscopy. Principal research question and specific aims: To assess the impact of access to a hand-held application on the timing of surveillance colonoscopy.
- Conditions
- Colo-rectal Cancer, Colon Polyp, Colonic Polyp, Rectal Polyp
- Trial name
- NCT04889352
- Testing
- Access to colonoscopy web app
- Where
- 2 sites in Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Colorectal Cancer, Adenoma Colon Polyp
Triple Assay of Rectal Mucus in the Diagnosis of Colorectal Cancer
Development of a multiomics assay for use on OriColTM sampled rectal mucus for detection of cancer and significant polyps in symptomatic patients on the Colorectal Urgent Suspected Cancer pathway.
- Trial name
- TRIOMIC (NCT06649123)
- Testing
- Oricol Test
- Where
- United Kingdom
- Volunteers
- 6,600 people
- Sponsor
- Origin Sciences
Colorectal Cancer Screening, Colon Polyps and Adenomas
Artificial Intelligence (AI) Technology May Help Patients to Understand Bowel Preparation Better Before They go for Colonoscopy.This Study Attempts to Leverage AI Chatbot in Counselling Patients to Improve Bowel Cleanliness, Reduce Anxiety as Well as Increase Procedural Satisfaction
Traditional pre-colonoscopy counselling requires significant time from healthcare workers to explain procedures, limiting efficiency and patient turnover.
- Conditions
- Colorectal Cancer Screening, Colon Polyps and Adenomas, Bowel Preparation Quality, Artificial Intelligence (AI)
- Trial name
- NCT06905782
- Testing
- AI chatbot study arm, Traditional counselling study arm
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Colonic Polyp, Colon Cancer
Endoscopic Characteristics of Colonic Tumours
The purpose is to investigate whether polyps that look different at colonoscopy, have formed via different mutations and have different risks of turning into cancer.
- Trial name
- C-LST (NCT01372696)
- Testing
- Sample of polyp
- Where
- Australia
- Sponsor
- Professor Michael Bourke
Colon Adenoma, Colon Polyp
The Australian Colonic Large Sessile Lesion Endoscopic Resection Study
A prospective, multicentre, observational study of all patients referred for endoscopic resection of sessile colorectal polyps sized ≥20 mm conducted with intention to treat analysis
- Trial name
- ACE (NCT03471793)
- Where
- Australia
- Volunteers
- 5,000 people
- Sponsor
- Western Sydney Local Health District
Colonic Adenoma, Colon Polyp
Comparison of the Benefit of Chromoendoscopy in Addition to High Definition White Light and Narrow Band Imaging for the Prediction of Submucosal Invasive Cancer in Colonic Lesions
To compare the incremental benefit of chromoendoscopy in addition to high definition white light and narrow band imaging in predicting submucosal invasion within laterally spreading lesions in the colon and in determining the…
- Conditions
- Colonic Adenoma, Colon Polyp, Submucosal Invasive Colon Adenocarcinoma, Colorectal Cancer
- Trial name
- LANS (NCT03506321)
- Testing
- chromoendoscopy, high definition white light and narrow band imaging
- Where
- Australia
- Volunteers
- 400 people
- Sponsor
- Western Sydney Local Health District
Colorectal Polyp, Colon Adenoma
Cold Snare Endoscopic Mucosal Resection (EMR) vs Cold EMR With Margin Snare Tip Soft Coagulation (STSC)
Randomised controlled trial comparing cold snare endoscopic mucosal resection (EMR) with cold snare EMR and adjuvant margin STSC in the complete resection of 15-40mm lateral-spreading adenomas
- Conditions
- Colorectal Polyp, Colon Adenoma, Colon Cancer
- Trial name
- NCT05041478
- Testing
- Cold Snare Endoscopic mucosal resection with adjuvant snare tip soft coagulation, Cold Snare Endoscopic Mucosal Resection
- Where
- Australia
- Volunteers
- 300 people
- Sponsor
- Western Sydney Local Health District
Colon Cancer, Rectal Cancer
Endoscopic Optical Coherence Tomography for Screening and Diagnosis of Colorectal Precancerous and Malignant Polyps
Colorectal cancer arises from the mucosal layer of the colon. Current screening is performed by flexible endoscopy, which involves visual inspection of the mucosal lining of the colon and rectum with an optical camera mounted on…
- Conditions
- Colon Cancer, Rectal Cancer, Cancer of the Rectum, Cancer of the Colon
- Trial name
- NCT05179837
- Testing
- Optical coherence tomography probe
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Washington University School of Medicine
Polyps, Adenoma Colon
CADDIE Trial - Computer Aided Diagnosis and Detection for Intelligent Endoscopy
Background: Colonoscopy is accepted to be the gold standard for screening of colorectal cancer (CRC). Most CRCs develop from adenomatous polyps, with colonoscopy accepted to be the gold standard for screening of CRC.
- Conditions
- Polyps, Adenoma Colon, Colorectal Polyp, Colon Polyp
- Trial name
- CADDIE (NCT04325815)
- Testing
- CADDIE- Computer Aided (AI) Device used in Endoscopy
- Where
- United Kingdom
- Volunteers
- 739 people
- Sponsor
- University College, London