Clinical trials: Colon Cancer Screening
Urothelial Carcinoma, Lynch Syndrome
Urothelial Cancer Screening in Individuals With Lynch Syndrome Using a Urine Tumor DNA Panel (LS-URO Study)
Lynch syndrome (LS) is an inherited cancer predisposition syndrome caused by pathogenic germline variants in DNA mismatch repair (MMR) genes.
- Trial name
- NCT06218433
- Testing
- Urothelial cancer screening using urine tumor DNA test, Urothelial cancer screening using urine cytology (comparator)
- Where
- 2 sites in Canada, Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Colon Polyp, Adenoma Colon
AmplifEYE Colonoscopy vs Standard Colonoscopy
Colonoscopy screening is proven to reduce mortality rates for colorectal cancer, which relies on early detection and removal of colonic polyps.
- Conditions
- Colon Polyp, Adenoma Colon, Serrated Polyp, Colonic Neoplasms
- Trial name
- NCT03814369
- Testing
- AmplifEYE
- Where
- Hong Kong
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Colorectal Carcinoma
A Multilevel Intervention to Increase Colorectal Cancer Screening Tests in Patients With Abnormal Fecal Immunochemical Test Results, PROACT Trial
This clinical trial studies whether an intervention that addresses two or more levels of care (multilevel intervention) increases follow-up of abnormal, non-invasive, colorectal cancer (CRC) screening test results.
- Trial name
- NCT06822530
- Testing
- Best Practice, Educational Intervention, Electronic Health Record Review
- Where
- United States
- Volunteers
- 682 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Colorectal Cancer
The PRIME-CRC Trial to Promote CRC Screening in Rural Communities
The investigators will expand an existing, patient-centered, health literacy strategy to promote longer-term adherence to colorectal cancer (CRC) screening in resource-limited, rural health clinics via colonoscopy or annual fecal…
- Trial name
- NCT04313114
- Testing
- health literacy appropriate education and demonstration, shared decision making, automated call reminders or automated texts
- Where
- 3 sites in United States
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Breast Carcinoma, Cervical Carcinoma
CATCH-UP Intervention in Increasing Cancer Screening and Prevention Care in Uninsured Patients at Community Health Centers
This randomized research trial studies the Community-based Health Information Technology (HIT) Tools for Cancer Screening and Health Insurance Promotion (CATCH-UP) intervention in increasing cancer screening and prevention care…
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma, Health Status Unknown
- Trial name
- NCT02355262
- Testing
- Informational Intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Colorectal Cancer
Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program
The investigators propose a randomized controlled trial to develop and evaluate the impact of promoting advice on diet and lifestyle recommendations for cancer prevention at colorectal cancer screening among individuals who may…
- Trial name
- LIFE-SCREEN (NCT04257526)
- Testing
- Diet and lifestyle advice following a positive FIT test and diagnostic colonoscopy.
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Colorectal Neoplasms, Colonic Polyp
Effectiveness of Artificial Intelligence-Assisted Colonoscopy for Adenoma Detection in Routine Clinical Practice : a Prospective Multicenter Randomized Trial
This study is a multi-center, randomized controlled trial designed to evaluate whether an artificial intelligence (AI) system can assist endoscopists to improve the detection rate of colorectal adenomas and cancers during…
- Conditions
- Colorectal Neoplasms, Colonic Polyp, Adenoma, Colorectal Cancer
- Trial name
- AI-COLOADR (NCT07307547)
- Testing
- AI-Assisted Colonoscopy
- Where
- China
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Cancer of the Colon
Colorectal Cancer Screening in a Community Health Setting
This randomized controlled pilot study at the Health Annex, Family Practice \& Counseling Network (FPCN), a community clinic in Southwest Philadelphia, aimed at providing data on the feasibility of a mailed FIT approach to CRC…
- Trial name
- NCT03072095
- Testing
- Text-only, Text + Lottery
- Where
- United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hepatitis C Virus Infection, Colorectal Cancer
CARES-HCV: Promoting Screening Uptake Among Diverse Baby Boomers
The purpose of the study is to examine the efficacy of educational materials to promote hepatitis C virus (HCV) screening and colorectal cancer (CRC) screening uptake among adults born between 1945-1965.
- Trial name
- NCT04980157
- Testing
- CARES-HCV
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Colorectal Cancer
Decision Aid to Technologically Enhance Shared Decision Making
Physicians face a challenge in promoting colorectal cancer screening (CRCS) in the face of multiple competing demands. A decision aid (DA) that clarifies patient preferences and improves decision quality could aid shared decision…
- Trial name
- DATES (NCT01514786)
- Testing
- Colorectal Web
- Where
- 14 sites in United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Colorectal Cancer, Colorectal Neoplasms
Increasing Engagement With Messages Regarding CRC Screening Among Adults Aged 45-49
In May of 2021, the United States Preventive Service Task Force (USPSTF) updated their colorectal cancer (CRC) screening guidelines by recommending screening at an earlier age for average-risk adults starting at the age of 45…
- Trial name
- CRC45+TEXT (NCT05281159)
- Testing
- Risk Information, Risk Information + Action
- Where
- 2 sites in United States
- Volunteers
- 20,509 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
BRCA1-Related Hereditary Breast and Ovarian Cancer Syndrome, BRCA2-Related Hereditary Breast and Ovarian Cancer Syndrome
A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American Families
This clinical trial studies whether a web-based program, Kindred, works to improve the understanding of genetic cancer risk and cancer genetic testing in African American families.
- Conditions
- BRCA1-Related Hereditary Breast and Ovarian Cancer Syndrome, BRCA2-Related Hereditary Breast and Ovarian Cancer Syndrome, Hereditary Neoplastic Syndrome, Lynch Syndrome
- Trial name
- NCT07542405
- Testing
- Discussion, Internet-Based Intervention, Survey Administration
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center
Colonoscopy, Colorectal Cancer
ScreenTalk to Improve Colorectal Cancer Screening Uptake Among First-degree Relatives of Patients: a Study Protocol
Participants in intervention group will receive the ScreenTalk intervention consisting of 3 module: measurement module, algorithmic tailoring module, and open dialogue module.
- Conditions
- Colonoscopy, Colorectal Cancer, First-degree Relatives
- Trial name
- NCT06710860
- Testing
- The intelligent voice-interactive tailored communication system-based intervention
- Where
- 3 sites in China
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection.
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Ann Arbor Stage I Lymphoma, Ann Arbor Stage II Lymphoma
- Trial name
- NCT05334069
- Testing
- Questionnaire Administration, Biospecimen Collection
- Where
- 747 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Adenoma, Bile Duct
The Effects of An Addition of Water Enema to PEG for Colon Preparation
The purpose of this study is to compare the preparation quality by using Ottawa Bowel Preparation Scale between the standard PEG preparation and the addition of water enema in participants scheduled for CRC screening
- Trial name
- NCT03270046
- Testing
- Water enema
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Colorectal Neoplasms
CHOICE: Communicating Health Options Through Information and Cancer Education
The purpose of this study is to determine the effectiveness of a two-component intervention, that combines academic detailing at the medical practice level and distribution of decision aids at the patient level, on adherence to…
- Trial name
- NCT00134589
- Testing
- Academic Detailing (Medical Practices)+Decision Aids (Patients)
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Cancer, Lung, Cancer, Breast
Early Detection of Five Common Cancers Using the ctDNA Analysing Test
This is a multi-centre, prospective cohort study, aiming to evaluate a blood test in early detection of the four common cancers, based on the investigation of the circulating tumour DNA (ctDNA).
- Conditions
- Cancer, Lung, Cancer, Breast, Cancer Liver, Cancer, Colorectal
- Trial name
- K-DETEK (NCT05227261)
- Where
- Vietnam
- Volunteers
- 9,057 people, healthy volunteers welcome
- Sponsor
- Gene Solutions
Colorectal Cancer
Participatory Research to Advance Colon Cancer Prevention
The overall goal of this study is to test strategies to raise rates of colorectal cancer screening among the Latino population in a federally qualified health center that operates multiple clinics.
- Trial name
- PROMPT (NCT03167125)
- Testing
- Automated Prompts, Automated Plus Live Prompts
- Where
- United States
- Volunteers
- 27,580 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Colorectal Cancer
Colonoscopy or Fecal Occult Blood Test in Screening Healthy Participants for Colorectal Cancer
RATIONALE: Screening tests, such as colonoscopy and fecal occult blood test, may help doctors find tumor cells early and plan better treatment for colorectal cancer.
- Trial name
- 00-046 (NCT00102011)
- Testing
- annual screening, fecal occult blood test, screening colonoscopy
- Where
- 4 sites in United States
- Volunteers
- 4,952 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Colorectal Cancer Screening, Hepatitis C Virus
Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening
This innovative Multilevel Action Toward Colorectal Cancer (CRC) and Hepatitis C Virus (HCV) Education and Screening (MATCHES) intervention aims to promote concurrent HCV and CRC screening among FQHC patients ages 45-75.
- Trial name
- MATCHES (NCT06745895)
- Testing
- MATCHES
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute