Clinical trials: Colitis, Ulcerative, open to volunteers
Ulcerative Colitis
A Trial COmparing staNdard of Care Versus Treat to Target With telemonitoRing and Patient Education in Patients With Ulcerative cOlitis Initiating Adalimumab
PHASE: IV DESCRIPTIVE: Randomized, interventional, open label multicenter trial POPULATION: Moderate to severe ulcerative colitis STUDY TREATMENTS: Patients will all receive Adalimumab 160/80/40mg EOW until V1 (W14) followed by…
- Trial name
- CONTROL (NCT04183608)
- Testing
- Adalimumab, Calprotectin, e-Monitoring
- Where
- 24 sites in France
- Volunteers
- 238 people
- Sponsor
- Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
Colitis, Ulcerative, Obesity
Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients
Approximately 20-40% of patients with ulcerative colitis (UC) are obese. The investigators have demonstrated that obesity adversely impacts disease course in patients with UC, leading to higher risk of persistently active…
- Trial name
- NCT04721873
- Testing
- Phentermine-Topiramate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego
Inflammatory Bowel Diseases, Ulcerative Colitis
Gut Microbiome in Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a chronic inflammatory condition for gastrointestinal tract. There have been numerous studies to reveal dysbiosis of fecal/mucosal microbiome composition in IBD patients but actual trend of…
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT03589183
- Where
- South Korea
- Volunteers
- 1,500 people
- Sponsor
- Kyunghee University Medical Center
Inflammatory Bowel Diseases, Crohn Disease
Effect of Incentive Integrated E-IBD Chronic Disease Management Model on the Quality of Life in IBD Patients
This study aims to prospectively explore the effect of incentive-integrated E-IBD (electronic inflammatory bowel disease) chronic disease management model on the improvement of IBD quality of life, and provide a more effective…
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- NCT05719766
- Testing
- education ,psycological support and social support
- Where
- 4 sites in China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Crohn's Disease, Ulcerative Colitis
GWA Study in Patients With Inflammatory Bowel Disease
The aim of this study is to identify new genes in Chinese patients that help investigators to understand the biological pathway and functions in a population in whom the incidence of Inflammatory Bowel Disease (IBD) is…
- Trial name
- NCT01140789
- Where
- Hong Kong
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Ulcerative Colitis, Irritable Bowel Syndrome
Efficacy of Probiotics in Patients With IBD
This research group plans to take patients with mild to moderate UC and diarrhea IBS diagnosed in the First Affiliated Hospital of Xinxiang Medical College as examples, and divide them into UC group and IBS group; Each group was…
- Trial name
- NCT05652621
- Testing
- probiotics
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Ulcerative Colitis, Inflammatory Bowel Diseases
Colectomy Reconstruction for Ulcerative Colitis, Ileorectal Anastomosis vs Ileal Pouch-Anal Anastomosis in Ulcerative Colitis.
Background There are no prospective trials comparing the two main reconstructive options after colectomy for Ulcerative colitis, ileal pouch anal anastomosis and ileorectal anastomosis.
- Conditions
- Ulcerative Colitis, Inflammatory Bowel Diseases, Ileostomy - Stoma
- Trial name
- CRUISE (NCT05628701)
- Testing
- Ileorectal anastomosis (IRA), Ileal pouch anal anastomosis (IPAA), ileostomy
- Where
- 4 sites in Sweden, United Kingdom
- Volunteers
- 100 people
- Sponsor
- Linkoeping University
Ulcerative Colitis
Prediction Model for Response to Biologics and Small Molecular Agent for UC
This prospective observational study is going to develop and validate a prediction model of response to biologic agents and small molecular agents for Korean patients with ulcerative colitis.
- Trial name
- NCT05186623
- Testing
- Vedolizumab, Ustekinumab, or Tofacitinib
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Asan Medical Center
Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA)
German Spondyloarthritis Inception Cohort
The German Spondyloarthritis Inception cohort (GESPIC) was started 2000 as a prospective, longitudinal, multicentre, nationwide study in Germany on patients with early SpA including ankylosing spondylitis (AS, also known as…
- Conditions
- Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA), Axial Psoriatic Arthritis (axPsA), Acute Anterior Uveitis (AAU)
- Trial name
- GESPIC (NCT01277419)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Charite University, Berlin, Germany
Crohn Disease, Ulcerative Colitis
Registry and Biorepository for IBD in Central Texas
This is a prospective, non-interventional registry and biorepository for patients with IBD. Longitudinal follow-up data is collected from both patients and their treating gastroenterologist during routine clinical encounters.
- Conditions
- Crohn Disease, Ulcerative Colitis, Inflammatory Bowel Diseases
- Trial name
- NCT04617184
- Testing
- NO INTERVENTION
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Texas at Austin
Crohn's Disease, Ulcerative Colitis
Epidemiology of Inflammatory Bowel Disease in the Songpa-Kangdong District, Seoul, Korea.
The purpose of this study is to evaluate the incidence, prevalence, clinical characteristics and prognosis of Crohn's disease and ulcerative colitis over time in a district of Seoul, Korea.
- Conditions
- Crohn's Disease, Ulcerative Colitis, Epidemiology, Korea
- Trial name
- NCT01731665
- Where
- South Korea
- Volunteers
- 2,000 people
- Sponsor
- Asan Medical Center
Ulcerative Colitis, Fecal Microbiota Transplantation
Fecal Microbiota Transplantation for Ulcerative Colitis
Fecal microbiota transplantation (FMT) is a strategy that infuses a fecal suspension containing a healthy donor's microbiota into a patient's gut to restore his/her intestinal microbiome.
- Trial name
- NCT03804931
- Testing
- Fecal microbiota transplantation, Infusion of Saline, 5-Aminosalicylic acid(5-ASA) and/or Prednisone
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Guangzhou First People's Hospital