Clinical trials: Cold
Nasal Congestion
A Nasal Spray for Relief of Nasal Congestion in Infants and Toddlers With Common Cold
The study will evaluate the safety and efficacy of the study medical device plus standard of care versus standard of care in subjects between 3 and 48 months (inclusive) presenting symptoms of a common cold.
- Trial name
- NCT05365789
- Testing
- Blocked Nose Baby nasal spray, Standard of care
- Where
- Poland
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Respiratory Tract Infections
Source Profiling of Biohazardous Aerosols in Hospitals
To characterise the physical parameters (number concentration, size distribution and their trajectories) of aerosols (droplets) generated in high risk procedures.
- Trial name
- NCT00517660
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Hospital Authority, Hong Kong
Orthostatic Hypotension
Autonomic Effects of Spinal Cord Stimulation in Spinal Cord Injury
The goal of this interventional crossover study is to determine the effects of transcutaneous spinal cord stimulation (TSCS) on the ability to perform moderate exercise and regulate core body temperature in the chronic spinal…
- Trial name
- NCT05960448
- Testing
- Transcutaneous Spinal Cord Stimulation (TSCS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Assessment, Self
Assessment Of Serum And Tissue Levels Of Cold-Inducible RNA-Binding Protein In Patients With Lichen Planus
Lichen planus (LP) is a chronic inflammatory mucocutaneous disease of unknown etiology. Pathogenesis of LP is not completely understood, but it's considered a T-cell-mediated autoimmune disease.
- Trial name
- NCT06260189
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sohag University
Skin Burns
The Counter-irritating Efficacy of Topical Povidone-iodine in Thermal Burns
Skin burns are one of the causes of disability, suffering and death in humans. Anecdotal, uncontrolled studies have shown the efficacy of povidone-iodine ointment in human skin burns, provided the preparation was applied shortly…
- Trial name
- NCT01350713
- Testing
- povidone iodine
- Where
- Israel
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Respiratory Syncytial Virus Infections
A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended Lower Respiratory Tract Infection Due to Respiratory Syncytial Virus in Healthy Late Preterm and Term Infants (MELODY)
The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics (PK), and antidrug antibody (ADA) response for MEDI8897 in healthy late preterm and term infants who are 35 weeks or greater gestational age and…
- Trial name
- MELODY (NCT03979313)
- Testing
- MEDI8897
- Where
- 198 sites in United States, Argentina and 29 more
- Volunteers
- 3,012 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Chemotherapy Adjuvant, Breast Cancer
Efficacy and Safety of Dignicap System for Preventing Chemotherapy Induced Alopecia
The efficacy and safety of the Dignicap System to prevent chemotherapy induced alopecia will be evaluated in women with early breast cancer undergoing adjuvant or neoadjuvant chemotherapy regimens.
- Trial name
- NCT01831024
- Testing
- Dignicap System
- Where
- 4 sites in United States
- Volunteers
- 110 people
- Sponsor
- Target Health Inc.
Acute Upper Respiratory Tract Infections
Clinical Trial of Safety and Efficacy of Ergoferon in Liquid Dosage Form in Treatment of Acute Upper Respiratory Tract Infections in Adults
The purpose of this study is: to evaluate safety of the liquid dosage form of Ergoferon in the treatment of acute upper respiratory tract infections in adults; to evaluate clinical efficacy of the liquid dosage form of Ergoferon…
- Trial name
- NCT01765920
- Testing
- Ergoferon
- Where
- 18 sites in Russia
- Volunteers
- 342 people
- Sponsor
- Materia Medica Holding
Thermoregulation, Cold Exposure
Effect of Pre-cooling on Whole-body Heat Loss During Exercise-heat Stress
Endurance exercise performance declines in hot environments as core body temperature increases. To enhance performance, body pre-cooling strategies, such as cold-water immersion have been employed to lower resting core…
- Conditions
- Thermoregulation, Cold Exposure, Heat Stress, Exercise
- Trial name
- NCT06670339
- Testing
- No Cooling, Pre-Cooling
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Rhinoplasty
The Effect of Ice Cold Mentholated Water Spray After Rhinoplasty
This clinical trial aims to evaluate the effects of a menthol-infused cold water spray on thirst perception, dry mouth, nausea, and physiological parameters in patients after rhinoplasty.
- Trial name
- NCT07233057
- Testing
- Menthol Cool Water Spray, Ice water spray
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Firat University
Upper Respiratory Tract Infection;, Acute Tracheobronchitis
A Registry Study on Reduning（a Chinese Medicine Injection）Used in Hospitals in China
This study was advocated by Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences in January 2013.
- Trial name
- NCT01824719
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Diarrhea, Upper Respiratory Infections
Children Immune Functions(2)
To investigate the effect of milk-based formulas on infections and immune functions in healthy children.
- Trial name
- NCT01731392
- Testing
- Milk with Bifidobacteria, Milk with non replicating lactobacilli
- Where
- Indonesia
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Metabolism Disorder
Cold Induced Futile Cycles In White Adipose Tissue
Investigation of futile cycles in white adipose tissue under cold conditions for thermogenesis using two substitutes for glucose metabolism (18F-FDG and 13C-Glucose).
- Trial name
- Metabol (NCT04614116)
- Testing
- External cooling, FDG PET/CT, 13C-Glucose injection
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Baden
Pelvic Organ Prolapse (POP)
Are There Benefits of Using Energy-based Devices for Opportunistic Salpingo-oophorectomy During Vaginal Hysterectomy Compared to a Standard Cold Approach?
This study compares two methods for removing the fallopian tubes and ovaries during vaginal hysterectomy for pelvic organ prolapse.
- Trial name
- NCT07379411
- Testing
- LigaSure MaryLand, Standard salpingo-oophorectomy technique
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Wolfson Medical Center
Herpes Labialis
An Exploratory Study to Investigate the Inflammatory Response During a Cold Sore Episode
This study will treat approximately 24 participants who experience cold sores. Patches will be applied to the cold sore for up to ten days, and the symptoms will be measured during daily clinic visits using non-invasive…
- Trial name
- NCT01653509
- Testing
- Acyclovir patch
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Venous Leg Ulcer
Air Cold Atmospheric Pressure Plasma Treatment for Acceleration of Venous Ulcer Healing
In this medical trial, a novel prototype of a medical device based on a Cold Atmospheric Air Plasma Jet for the treatment is clinically tested on patients with venous leg ulcers.
- Trial name
- PLASFRI-CUV (NCT05894096)
- Testing
- Cold Atmospheric Plasma Jet Treatment, Alginate Patch
- Where
- 5 sites in Spain
- Volunteers
- 68 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Pain, Diabetes Mellitus
Cold Spray for Insulin-Injection Pain in the Emergency Department
This randomized, double-blind, placebo-controlled, within-patient crossover trial evaluated whether a vapocoolant (cold) spray applied before subcutaneous insulin injection reduces injection pain compared with a placebo…
- Trial name
- NCT07728162
- Testing
- Cold (vapocoolant) spray
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Abant Izzet Baysal University
Healthy
Galactooligosaccharide, Immune Strength, and Digestive Health in Older Adults Over Cold and Flu Season
The purpose of this research study is to determine whether a functional fiber, galactooligosaccharide, can help maintain immune strength and digestive health in free-living older adults.
- Trial name
- GOS (NCT01302561)
- Testing
- Sucrose, Galactooligosaccharide
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Florida
Biliary Stricture, Bile Duct Stenosi
Biliary Complications in Live Donor Liver Transplantation
The study was designed as a prospective cohort study. The effects of hot and cold ischemic times during live donor liver transplantation on postoperative 1-3 and 6 month follow up biliary complications will be investigated.
- Conditions
- Biliary Stricture, Bile Duct Stenosi, Bile Leak, Bile Duct Injury
- Trial name
- NCT03673033
- Testing
- liver transplantation
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Inonu University
Ischemia
Study Of The Metabolic Parameters Of Uterine Muscle Cells
To date, no transplant has allowed pregnancy from a donor in a state of brain death. One of the main reservations lies in the ischemic properties of the uterine graft between the sampling time and the grafting time.
- Trial name
- NCT03784157
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France