Clinical trials: Cohort
Obesity, Thyroid
Can Thyroidectomy be Considered Safe in Obese Patients?
Obesity is a growing public health concern in most western countries. More and more patients with high body mass index (BMI) are undergoing surgical procedures of all kinds and, in this context, obese patients are undergoing…
- Conditions
- Obesity, Thyroid, Surgery--Complications
- Trial name
- NCT04273711
- Where
- Italy
- Volunteers
- 813 people
- Sponsor
- University of Cagliari
HIV Infections
Cabotegravir Plus Rilpivirine Long-acting Regimen in the Swiss HIV Cohort Study:Uptake, Outcome, and Risk Factors for Treatment Failures
This study aims to characterize Swiss HIV Cohort Study participants initiating the CAB+RPV LA regimen, assess adherence to Swiss label indications, and describe treatment outcomes in this large, multicentre, heterogeneous…
- Trial name
- NCT06405464
- Testing
- VOCABRIA 30Mg Tablet, EDURANT 25Mg Tablet, Cabotegravir Injectable Suspension
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- University of Zurich
Atrial Fibrillation
Stepwise Strategy for Treatment of Atrialfibrillation Substrate Study
Electrical/pharmacological cardioversion improves structural remodeling of left atrium. We hypothesized that radiofrequency ablation surgery for atrial fibrillation has a higher success rate and a lower recurrence rate of atrial…
- Trial name
- SAFE (NCT07129564)
- Testing
- treatment react
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Yuehui Yin
PTSD
Concentrated Exposure Therapy for Post-traumatic Stress Disorder - a Cohort Study
Post-traumatic stress disorder (PTSD) is a prevalent and disabling condition. Trauma-focused psychotherapy, including cognitive behavioural therapy (CBT), are among the recommended first-line treatment alternatives.
- Trial name
- NCT05598099
- Testing
- Concentrated cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 42 people
- Sponsor
- Haukeland University Hospital
ICU Patients, Surgical
Implementation of Clinical Nutrition Practice Guidelines in Surgical ICUs
The goal of this interventional clinical trial is to evaluate whether the implementation of an evidence-based, context-adapted clinical nutrition practice guideline can improve clinical nutrition management in surgical intensive…
- Conditions
- ICU Patients, Surgical, Nutrition Intervention, Enteral Nutrition
- Trial name
- NCT07337798
- Testing
- Guideline Implementation
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
HCC
TACE Versus HAIC, Combined With PD-1 Inhibitors and Lenvatinib for Unresectable Hepatocellular Carcinoma
Although the combination of transarterial chemoembolization (TACE) with PD-1 inhibitor plus lenvatinib has become a new standard, the therapeutic efficacy for unresectable hepatocellular carcinoma (uHCC) still requires…
- Trial name
- NCT07340502
- Testing
- TACE, HAIC, PD-1inhibitors
- Volunteers
- 364 people
- Sponsor
- Tongji Hospital
Kidney Cancer, Renal Cell Cancer
Cabozantinib and Nivolumab Among Older Patients With Renal Cell Carcinoma
The goal of the study is to describe real-life use and exposition to nivolumab-cabozantinib among older patients with metastatic clear-cell renal cell cancer
- Trial name
- CABOLD (NCT06934057)
- Testing
- Nivolumab, Cabozantinib
- Where
- 7 sites in France
- Volunteers
- 50 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
HIV Infections
Observational Cohort of HIV Infected Adults and Children in the PHPT Network Hospitals in Thailand
Since 2004, the Thai Ministry of Public Health has massively scaled up antiretroviral treatment programs to provide therapy to more than 80,000 patients with partial support of the Global Fund to fight AIDS, Tuberculosis and…
- Trial name
- NCT00433030
- Where
- 38 sites in Thailand
- Volunteers
- 2,816 people
- Sponsor
- Institut de Recherche pour le Developpement
Carpal Tunnel Syndrome
Sonographic Follow-up of Patients With Carpal Tunnel Syndrome Undergoing Surgical or Conservative Treatment
In wrists with carpal tunnel syndrome (CTS) the sonographically measured largest cross-sectional area (CSA) of the median nerve is increased.
- Trial name
- CTS (NCT00694265)
- Testing
- Decompression, Conservative treatment
- Where
- Switzerland
- Volunteers
- 55 people
- Sponsor
- University of Bern
Osteoporotic Fractures
Senile Osteoporotic Fractures Cohort Study（SOFCS）
Osteoporotic fracture is one of the main causes of disability and death in elderly patients. Specific disease cohort study is an important basis for accurate prevention and treatment of senile osteoporotic fractures.
- Trial name
- NCT05848167
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Suzhou Municipal Hospital
Surveillance Endoscopy for Colorectal Cancer, Artificial Intelligence
Surveillance Modified by Artificial Intelligence in Endoscopy (SMARTIE)
Evaluation of an artificial intelligence system for polyp detection (CADe)
- Conditions
- Surveillance Endoscopy for Colorectal Cancer, Artificial Intelligence, Polyps of Colon, CADe
- Trial name
- SMARTIE (NCT05006092)
- Testing
- ENDOMIND
- Where
- Germany
- Volunteers
- 1,149 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Major Depressive Disorder, Magnetic Resonance Imaging
Multimodal Magnetic Resonance Imaging-based Study of Electroconvulsive Efficacy Prediction in Adolescents With Depression: a Multicenter Prospective Cohort Study
The aim of this project is to investigate the multimodal magnetic resonance brain imaging changes in adolescents with major depressive disorder (MDD) before and after electroconvulsive therapy.
- Conditions
- Major Depressive Disorder, Magnetic Resonance Imaging, Electroconvulsive Therapy
- Trial name
- NCT05889234
- Testing
- Modified Electroconvulsive Therapy, Conventional pharmacotherapy
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Venous Congestion
Portal Vein Pulsatility Index to Assess Fluid Intolerance
This study uses the portal vein pulsatility index (PVPI) to assess fluid intolerance amongst fluid responders.
- Trial name
- NCT06440772
- Testing
- Ringer's Lactate Crystalloid Solutions
- Where
- Romania
- Volunteers
- 50 people
- Sponsor
- Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu
Port Wine Stain, Klippel Trenaunay Syndrome
French National Cohort of Children With Port Wine Stain
Port Wine Stain on a limb can be either isolated or associated with complications (venous or orthopedic impairment, arteriovenous malformations), leading sometimes to complex syndromes (Klippel-Trenaunay syndrome,Parkes-Weber…
- Conditions
- Port Wine Stain, Klippel Trenaunay Syndrome, Parkes Weber Syndrome
- Trial name
- CONAPE (NCT01364857)
- Testing
- search for polymorphisms of RASA1 gene
- Where
- 17 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Tours
Coronary Heart Disease, Stroke
Hamburg City Health Study - a German Cohort Study
The Hamburg City Health Study (HCHS) is a large, prospective, long-term, population-based cohort study and a unique research platform and network to obtain substantial knowledge about several risk and prognostic factors in major…
- Conditions
- Coronary Heart Disease, Stroke, Dementia, Cancer
- Trial name
- HCHS (NCT03934957)
- Where
- Germany
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Dissection of the Superior Mesenteric Artery
Stent Implantation for Patients With SIDSMA
This study aims to evaluate the prognosis in patients with spontaneous isolated dissection of the superior mesenteric artery (SIDSMA) who have been treated with stents.
- Trial name
- NCT03916965
- Where
- China
- Volunteers
- 102 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Lupus Nephritis (LN)
High Quality Evidence of Guangzhou Lupus Nephritis Cohort (HOPE Cohort)
The goal of this observational study is to learn about the long-term renal and patient's survival of lupus nephritis (LN) patients in China.
- Trial name
- HOPE (NCT06682507)
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
COVID-19
Rehabilitation in Severely Ill Inpatients With COVID-19
Inpatient rehabilitation of severe-to-critical COVID-19 patients(A longitudinal, single-center retrospective cohort)
- Trial name
- NCT05104411
- Testing
- Rehabilitative intervention
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Seoul National University Bundang Hospital
Substance Use Disorders
Contingency Management Using Smartphone App in Patients With SUD
The purpose of this research study is to test the acceptance and efficacy of a smartphone app (DynamiCare Rewards) for patients with substance use disorder (SUD) who are in active treatment and recovery at BrightView.
- Trial name
- NCT04162132
- Testing
- Smartphone app
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- BrightView LLC
Psoriatic Arthritis, Psoriasis
Pain Mechanisms and Ultrasonographic Disease Activity in Psoriatic Arthritis
The objective of the study is to investigate pain mechanisms, comorbidity status, biomarkers, patient reported outcome measures, ultrasonographic (US) inflammatory activity and association between these features in patients with…
- Conditions
- Psoriatic Arthritis, Psoriasis, Healthy Controls
- Trial name
- PIPA (NCT02572700)
- Testing
- Clinical examination, blood sampling, ultrasonic assessment, and questionnaires
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Frederiksberg University Hospital