Clinical trials: Cognitive Wellness
Healthy Aging, Healthy
Investigating the Effects of Daily Consumption of Blueberry (Poly)Phenols on Vascular Function and Cognitive Performance
Foods rich in certain (poly)phenols, particularly flavonoids, such as berries and cocoa, have been shown to improve measures of vascular function as well as cognitive performance in human intervention studies.
- Trial name
- BluFlow (NCT04084457)
- Testing
- Wild Blueberry powder
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- King's College London
Cardiovascular Diseases, Cognition
Acute Impact of Whey Protein-enriched Milk Fat Globule Membrane Supplementation on Postprandial Markers of Heart and Brain Health
In a single-blind, randomised, placebo-controlled crossover manner, this study aims to assess the impact of a high-fat mixed meal containing a whey protein (WP)-enriched milk fat globule membrane (MFGM) powdered ingredient on…
- Conditions
- Cardiovascular Diseases, Cognition, Overweight or Obesity, Postmenopausal Women
- Trial name
- NCT06953232
- Testing
- Whey protein-enriched milk fat globule membrane supplement, Whey protein-based supplement
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Psychological Well Being, Behavioral Management
Behavioral Management and Psychological Well-Being
The aim of present study is to evaluate whether a program of behavioral and cognitive procedures for emotional control, and assertive training, produces well-being and improvement in quality of life of healthy volunteers.
- Trial name
- NCT01823601
- Testing
- Behavioral Management Program, Seminars in Health
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Centro de Estudos em Medicina Comportamental
Cognitive Dysfunction, Covid19
Improving Cognitive Health in COVID-19 Survivors
The primary objective of this study is to investigate the efficacy of AKL-T01, a remotely-delivered digital cognitive intervention, relative to a waitlist control in improving cognitive functioning in COVID-19 survivors.
- Trial name
- NCT04843930
- Testing
- AKL-T01
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Weill Medical College of Cornell University
Mild Cognitive Impairment
Improving Neurological Health With Acetylcholine Via Neuroplasticity-based Computerized Exercise in Mild Cognitive Impairment
This study is a validation study to evaluate efficacy of two neuroplasticity-based, computerized cognitive training programs to improve neurological and neuropsychological health in older adults with mild cognitive impairment…
- Trial name
- INHANCE-MCI (NCT07243600)
- Testing
- Computerized speed-based cognitive training, Computerized executive function cognitive training
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Posit Science Corporation
Sleep Hygiene, Sarcopenia
Sleep Hygiene, Sarcopenia, and Cognitive Function in Respiratory Disease
We aim to clarify the relationship between sleep hygiene and the onset of sarcopenia or cognitive dysfunction using sleep time, arousal, and sleep quality as indicators in COPD or IPF patients, and clarify the effects of sleep…
- Conditions
- Sleep Hygiene, Sarcopenia, Cognitive Function, COPD
- Trial name
- NCT05193136
- Where
- Japan
- Volunteers
- 120 people
- Sponsor
- National Hospital Organization Minami Kyoto Hospital
Multiple Sclerosis
Electrical Brain Stimulation for Treatment of Secondary Symptoms in Multiple Sclerosis
Multiple Sclerosis (MS) is an autoimmune disease associated with physical disability, psychological impairment, and cognitive dysfunction. As a result, the disease burden is high, and treatment options are limited.
- Trial name
- NCT06401928
- Testing
- transcranial direct current stimulation, transcranial direct current stimulation combined with cognitive training
- Where
- Iran
- Volunteers
- 53 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Nicotine Dependence, Smoking Cessation
D-cycloserine (DCS) Pretreatment + CBT + Nicotine Replacement Therapy for Smoking Cessation (DCS)
1. Compare the relative efficacy of ten weeks of once weekly 250 mg D-cycloserine (DCS) vs. placebo (both in conjunction with cognitive behavioral therapy (CBT) and nicotine replacement therapy (NRT) on reducing cigarette smoking…
- Trial name
- DCS (NCT01842334)
- Testing
- Cognitive Behavioral Therapy, Nicotine Replacement Therapy
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Wellness, Burnout
Effect of Sleep Deprivation on Cognitive Function Among Cardiology Fellows
A reliable method for monitoring sleep, stress, and burnout among cardiology fellows is critically needed. To address this gap, our team aims to utilize the cost-effective WHOOP strap 4.0 wearable device to continuously capture…
- Conditions
- Wellness, Burnout, Sleep Deprivation, Executive Function
- Trial name
- NCT05513339
- Testing
- WHOOP strap 4.0
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Dementia, Caregiver
ED PLWD/Care Partner Text Messaging
The purpose of this research study is to develop and test a text-messaging intervention for emergency department (ED) discharge care transitions experienced by caregivers of older adults with cognitive impairment.
- Conditions
- Dementia, Caregiver, Emergency Department, Mobile Health Technology (mHealth)
- Trial name
- CAPTURE (NCT07423871)
- Testing
- CAPTURE Text Message Care Transition Support
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Dementia Risk Factors, Prevention
The REMINDER4Care Program for Older Adults Supported by Residential and Daycare Facilities
Dementia incidence is rising, posing a public health challenge, but 45% of cases can be prevented by addressing modifiable risk factors.
- Conditions
- Dementia Risk Factors, Prevention, Cognitive Health
- Trial name
- REMINDER4Care (NCT06922071)
- Testing
- REMINDER4Care
- Where
- Portugal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Schizophrenia, Psychotic Disorders
Medication Adherence in Schizophrenia: Development of a CBT-Based Intervention
This is a randomized pilot study of an intervention based on principles of Cognitive Behavioral Therapy (CBT). This intervention is the Health Dialogue Intervention (HDI) and will be compared to a traditional medical model of…
- Trial name
- NCT00980252
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Illinois at Chicago
Breast Cancer, Psychological Distress
The Validation of ICBT Clinical Trial: Disease Stress Adjustment in Breast Cancer Patients
Breast cancer and its treatment can cause ongoing emotional distress, including anxiety, depressive symptoms, stress-related reactions, and difficulties adjusting to life after treatment.
- Trial name
- ICBT-TW-2 (NCT07835698)
- Testing
- Internet-Based Cognitive Behavioral Therapy Program for Breast Cancer Survivors, Treatment as Usual (TAU)
- Volunteers
- 100 people
- Sponsor
- National Health Research Institutes, Taiwan
Suicide, Psychosis
Cognitive Behavioral Suicide Prevention for Psychosis: Aim 1
The investigators are modifying and testing the preliminary effectiveness and implementation of a Cognitive Behavioral Suicide Prevention for psychosis (CBSPp) intervention.
- Trial name
- NCT04689867
- Testing
- Cognitive Behavioral Suicide Prevention for psychosis CBSPp)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Michigan
Health Adult Subjects, Maltreament
Mindfulness Intervention for Maltreatment-Related Cognitive Decline
The goal of this clinical trial is to examine whether an online mindfulness-based training program can help improve cognitive function including attention, emotional regulation, and mental health (such as depression and anxiety)…
- Trial name
- NCT07066800
- Testing
- Mindfulness-Based Online Training Program
- Where
- South Korea
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Chilgok Hospital
Depression, Anxiety
CAMH - McMaster Collaborative Care Initiative For Mental Health Risk Factors In Dementia
Age remains the single most significant risk factor for developing dementia, particularly Alzheimer's dementia (AD). Given the rate at which Canada's population is aging, the quest to determine modifiable risk factors, whether by…
- Conditions
- Depression, Anxiety, Mild Cognitive Impairment
- Trial name
- CCI (NCT02955719)
- Testing
- Sertraline, Venlafaxine, CBT/Psychological Therapy
- Where
- Canada
- Volunteers
- 145 people
- Sponsor
- Centre for Addiction and Mental Health
Cognitive Function 1, Social, Mental Health Wellness 1
Effects of an Exercise Program on Cognition and Brain in Overweight/Obese Preadolescent Children
The ActiveBrains project aims to examine whether a 5-months physical exercise program has benefits on cognition and brain, as well as on selected physical and mental health outcomes in preadolescent overweight/obese children.
- Conditions
- Cognitive Function 1, Social, Mental Health Wellness 1, Obesity, Overweight
- Trial name
- ActiveBrains (NCT02295072)
- Testing
- A 5-months physical exercise-based program
- Volunteers
- 110 people
- Sponsor
- Universidad de Granada
Anxiety, Depression
Optimizing Duration of Therapist-guided Internet-delivered Cognitive Behaviour Therapy
Depression and anxiety are common and prevalent conditions that are frequently under treated. In an attempt to increase timely and accessible psychological treatment, Internet-delivered Cognitive Behaviour Therapy (ICBT) has…
- Trial name
- NCT04228575
- Testing
- Internet-delivered cognitive behaviour therapy
- Where
- Canada
- Volunteers
- 410 people
- Sponsor
- University of Regina
Stroke
Cognitive Strategies for Improving Health Outcomes And Managing Risk Post-Stroke
The proposed research will further develop the CHAMPS intervention which is self-management intervention to learn new skills, despite current health status of experience a stroke.
- Trial name
- CHAMPS (NCT06066788)
- Testing
- CHAMPS
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of New Mexico
Chronic Pain
Integrating Nonpharmacologic Strategies for Pain With Inclusion, Respect, and Equity
INSPIRE creates a trilingual mobile app and telehealth coaching program to promote non-pharmacologic strategies for pain management with Black, Chinese, and Latinx communities in the San Francisco Bay Area.
- Trial name
- INSPIRE (NCT06183281)
- Testing
- CBT, Mindfulness, and Movement
- Where
- 2 sites in United States
- Volunteers
- 586 people
- Sponsor
- University of California, San Francisco