Clinical trials: Cognitive Wellness
Binge-Eating Disorder, Bulimia Nervosa
Building an Equitable and Accessible System of Eating Disorder Care for VA, DoD, and Underrepresented Americans
When untreated, eating disorders present with tremendous burdens to affected active duty Service members and Veterans and their families, and are very costly to the DoD and VA healthcare system.
- Conditions
- Binge-Eating Disorder, Bulimia Nervosa, Veterans Health, Cognitive Behavioral Therapy
- Trial name
- EASED (NCT05304104)
- Testing
- Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- VA Connecticut Healthcare System
Cognitive Function
Radicle Clarity DSTTM: A Study Assessing the Impact of Health and Wellness Products on Mental Clarity and Related Health Outcomes
Radicle Clarity DSTTM: A randomized, double-blind, placebo-controlled direct-to-consumer study assessing the impact of health and wellness products on mental clarity and related health outcomes.
- Trial name
- NCT07342192
- Testing
- RS Clarity Active Product
- Where
- United States
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Long COVID, Acute COVID-19
Chronic Stress as a Risk Factor for Long COVID
The disease caused by the pathogen SARS-CoV-2 is known as coronavirus disease with the acronym COVID-19. The acute phase of this condition typically lasts one to two weeks and usually results in a full recovery.
- Trial name
- StressLoC (NCT05652634)
- Where
- Austria
- Volunteers
- 380 people
- Sponsor
- Medical University of Graz
Sleep, Sleep Restriction
Performance, Mood, and Brain and Metabolic Functions During Different Sleep Schedules
This proposed project will investigate whether a variable or a stable sleep schedule will be more effective in minimizing neurobehavioural and metabolic deficits when total sleep opportunity across two weeks is below the…
- Trial name
- STAVAR (NCT04731662)
- Testing
- Short sleep, Variable short sleep
- Where
- Singapore
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Menopause, Sleep Disturbance
Radicle Revive 24: A Study of Health and Wellness Products on Menopausal Health and Related Health Outcomes
A randomized, double-blind, placebo-controlled, direct-to-consumer trial assessing the impact of health and wellness products on hormonal health and associated health outcomes in women with menopausal health issues
- Conditions
- Menopause, Sleep Disturbance, Anxiety, Depression
- Trial name
- NCT06749288
- Testing
- Radicle Revive Active Study Product 4.1 Usage
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Mild Cognitive Impairment
The Effects of Cannabidiol and Homotaurine in Patients With Mild Cognitive Impairment
A Randomized Clinical Trial that will compare the effects of Cannabidiol and Homotaurine in cognition and mental health in patients with Mild Cognitive Impairment and APOE ε4 carriers.
- Trial name
- NCT05022186
- Testing
- Cannabidiol Oil, Homotaurine
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Aristotle University Of Thessaloniki
Any Chronic, Non-traumatic Orthopedic Condition
Testing an AI Large Language Model Tool for Cognitive Debiasing in Musculoskeletal Care
The goal of this clinical trial is to find out whether using an artificial intelligence (AI) tool called a Large Language Model (LLM) can help patients think more clearly about their symptoms and improve their trust and…
- Trial name
- NCT07022769
- Testing
- LLM-facilitated cognitive debiasing aid
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Texas at Austin
Subjective Cognitive Concerns, Mild Cognitive Impairment
Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD
The goal of this study is to objectively test one's sense of smell, called olfaction, in participants with Subjective Cognitive Concerns (SCC), Mild Cognitive Impairment, Mild Behavioral Impairment (MBI), and age-matched…
- Conditions
- Subjective Cognitive Concerns, Mild Cognitive Impairment, Mild Behavioral Impairment, Healthy Aging
- Trial name
- NCT05881239
- Testing
- AROMHA Brain Health Test
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Diabetes Mellitus, Hypertension
Community-based E-Health Program for Older Adults Living With Chronic Diseases
With increased aging population, there is a higher rate of having chronic diseases and cognitive impairment. In order to achieve successful aging, it is important for community-dwelling older adults to perform better…
- Conditions
- Diabetes Mellitus, Hypertension, Hyperlipidemias
- Trial name
- CeHP (NCT04560296)
- Testing
- Community-based E-Health Program, usual self-management and follow up with doctors/nurse
- Where
- 9 sites in Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans 3.0
Women Veterans are the fastest growing segment of VA users, with most users in midlife. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Hypertension
- Trial name
- EMPOWER (NCT07356479)
- Testing
- EBQI Booster (EBQI/B), EBQI Booster + External Facilitation (EBQI/B+EF)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- VA Office of Research and Development
Stress Disorders, Post-Traumatic
Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication
The purpose of this clinical trial is to learn whether existing treatments for posttraumatic stress disorder (PTSD) can be improved.
- Trial name
- AWARE (NCT06088303)
- Testing
- Adjunctive writing to amplify response and engagement (AWARE), Cognitive processing therapy (CPT), Prolonged exposure (PE)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Boston University
Schizophrenia, Schizoaffective Disorder
Integrative Neuro-social Cognitive Strategy Programme for Instilling REcovery (INSPIRE) a Community-Based Cognitive Remediation Trial
Adults with serious mental illnesses (such as schizophrenia and schizoaffective disorders) often experience a range of cognitive difficulties (such as memory, problem solving difficulties) that affect their ability to lead…
- Trial name
- NCT06286202
- Testing
- Cognitive Remediation: Adapted Neuropsychological and Education Approach to Remediation (NEAR), Standard Psychiatric Rehabilitation at Anglican Care Centers
- Where
- 5 sites in Singapore
- Volunteers
- 160 people
- Sponsor
- Singapore Institute of Technology
Cognitive Aging, Adverse Childhood Experiences
Physical Exercise for Augmenting Cognitive Health (PEACH)
PEACH is a pilot project which is being conducted to determine the feasibility and acceptability of a 12-week home-based exercise intervention among Black and African American adults.
- Trial name
- PEACH (NCT04922710)
- Testing
- Home-based aerobic exercise
- Where
- 2 sites in United States, Jamaica
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Depression
Comparing Delivery Methods of Cognitive Behavioral Therapy for Depressed African-American Dementia Caregivers
This study will compare the effectiveness of face-to-face cognitive behavioral therapy versus telephone-based cognitive behavioral therapy for treating African Americans who care for family members with dementia.
- Trial name
- NCT00769769
- Testing
- Psychotherapy
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Robert L. Glueckauf
Cystic Fibrosis (CF), Fatigue
CF Wellness Program
This study is a pilot randomized control trial (RCT; N=80) comparing the Cystic Fibrosis Wellness Program (CFWP) to usual care (UC) to evaluate (1) Intervention Adherence (completion of the CFWP Coaching Sessions) (2) Study…
- Conditions
- Cystic Fibrosis (CF), Fatigue, Sleep Quality, Insomnia
- Trial name
- NCT07071324
- Testing
- CF Wellness Program
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Johns Hopkins University
MCI, Mild Cognitive Impairment
Telehealth-Adapted Compensatory Training and Intervention for Cognition
The goal of this clinical trial is to develop a five-week virtual cognitive training intervention for people with Mild Cognitive Impairment (MCI) based off an existing eight-week intervention.
- Conditions
- MCI, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI)
- Trial name
- TACTIC (NCT07366346)
- Testing
- Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (ME-CCT-MCI), Brief Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (bME-CCT-MCI)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
Cognition
Investigating the Effects of a Haskap Berry Supplement on Cognitive Health
This study aims to investigate the postprandial (2h) and longer term (4 week) effects of a haskap berry supplement on cognitive, vascular, and metabolic function in healthy ageing adults aged 50+.
- Trial name
- HACVAC (NCT07119788)
- Testing
- Pure haskap berry powder, Vitamin-and mineral-enhanced haskap berry powder
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Reading
Stress
Early Interventions for Primary Care Patients With Stress-related Ill-health: a Non-inferiority RCT
Stress-related ill-health is rated one of the largest health challenges in the western world. The most empirically supported treatment for stress-related disorders is cognitive behaviour therapy (CBT), but accessibility is low…
- Trial name
- NCT04820283
- Testing
- Care manager intervention (nurse), CBT
- Where
- Sweden
- Volunteers
- 172 people
- Sponsor
- Karolinska Institutet
Anxiety, Stress
An Exploratory Investigation of a Supplement to Promote Cognitive Health Benefits
The Smart Supplement has 20 vitamins and minerals that have strong track records of demonstrating positive health effects, both physiologically and cognitively.
- Conditions
- Anxiety, Stress, Memory Deficits, Cortisol Overproduction
- Trial name
- NCT05523115
- Testing
- Heights Smart Supplement
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Heights
Physical Activity, Mental Health Wellness 1
Physical Exercise for Education ('Fit to Study')
Neuroscience evidence suggests that physical exercise can influence brain function and structure, both immediately and in the long-term.
- Conditions
- Physical Activity, Mental Health Wellness 1, Cognitive Function 1, Social, Academic Attainment
- Trial name
- FTS (NCT03286725)
- Testing
- Physical Education (PE) Programme
- Where
- United Kingdom
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University