Clinical trials: Cognitive Wellness
Schizophrenia, Hallucinations
Evaluation of Internet-based Cognitive Behavioral Self-help Treatments for People With Psychosis
Schizophrenia is a severe mental disorder which is accompanied by an enormous individual and societal burden. Despite established efficacy of cognitive behavioral therapy for psychosis (CBTp), its dissemination into routine…
- Conditions
- Schizophrenia, Hallucinations, Persecutory Delusion
- Trial name
- EviBaS (NCT02974400)
- Testing
- Internet-based, CBT-oriented, guided self-help
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 101 people
- Sponsor
- University of Bern
Schizophrenia, Schizoaffective Disorder
A Study of Varenicline for Prevention of Relapse to Smoking in Patients With Schizophrenia or Bipolar Disorder
Varenicline (Chantix) is a smoking cessation treatment that was approved in 2006 by the FDA for treatment of nicotine dependence and may be particularly beneficial in smokers with schizophrenia or bipolar disorder.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Smoking
- Trial name
- SCRP (NCT00621777)
- Testing
- Varenicline
- Where
- 10 sites in United States
- Volunteers
- 247 people
- Sponsor
- Massachusetts General Hospital
Postpartum Depression (PPD), Cardiac Event
Living Healthy for Moms RCT
LHMoms is a novel integrated care intervention that focuses intensively on care continuity and community-to-healthcare linkages for postpartum birthing individuals.
- Trial name
- LHMoms (NCT06666400)
- Testing
- LHMoms Intervention, No intervention
- Where
- 4 sites in United States
- Volunteers
- 21 people
- Sponsor
- Columbia University
Stress, Cognitive Impairment
Mindfulness-Based Health Promotion Program for Educators (MBHP - Educa).
In the last few decades, the world has seen a significant increase in the occurrence of occupational diseases related to Burnout Syndrome (professional exhaustion) and stress in educators.
- Conditions
- Stress, Cognitive Impairment, Burnout Syndrome
- Trial name
- Mindfulness (NCT03839030)
- Testing
- MBHP-Educa
- Where
- Brazil
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Marcelo Demarzo, MD, PhD
Spine Surgery
SpinePal Open Pilot
SpinePal is a self-guided digital intervention developed for patients undergoing spine surgery. The goal of this study is to learn if SpinePal is acceptable to people undergoing spine surgery.
- Trial name
- NCT07737912
- Testing
- SpinePal
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Trustees of Dartmouth College
Breast Cancer, Breast Neoplasms
Mental and Cognitive Health and Physical Activity in the Perioperative Breast Cancer Setting
This study evaluates the complex relationships between mental health, cognitive function, and physical activity before surgery in patients with stage I-III breast cancer.
- Conditions
- Breast Cancer, Breast Neoplasms, Cancer, Breast, Cancer of the Breast
- Trial name
- NCT06595901
- Testing
- Actigraph, Questionnaires, BrainBaseline application
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Washington University School of Medicine
Homelessness, Mental Health Conditions
ASPIRE Cognitive Enhancement Study
Cognitive impairments are present in up to 80% of homeless individuals, and may contribute to homelessness in Operation Enduring Freedom / Operation Iraqi Freedom / Operation New Dawn (OEF/OIF/OND) Veterans.
- Trial name
- ACES (NCT02657954)
- Testing
- CCT, HCE
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- VA Office of Research and Development
Coronary Artery Disease, Smoking Cessation
Effects of Cognitive-behavioral Education and Exercise Interventions on Smoking Cessation
The purpose of the study is to adopt the Trans-theoretical Model to facilitate step-by-step changes in a patient's smoking behavior and explore the effect of "Cognitive-Behavioral Education Course" and "Exercise Program" on…
- Trial name
- NCT05079958
- Testing
- cognitive-behavioral education, 12-week brisk walking
- Where
- Taiwan
- Volunteers
- 172 people
- Sponsor
- Cathay General Hospital
Mental Health Issue, Alcohol Use Disorder
Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individuals
The current study aims to assess the acceptability and feasibility of an adapted version of Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS) for use with signing Deaf adults.
- Conditions
- Mental Health Issue, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- NCT05520190
- Testing
- Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Rochester
Psychological Stress
A Randomised Controlled Trial of Self-help Mindfulness-based Cognitive Therapy for Health Workers
This study examines whether a mindfulness-based self-help book is effective at reducing healthcare workers' levels of stress and improving their wellbeing.
- Trial name
- MindSHINE2 (NCT03030040)
- Testing
- The self-help book: Williams, M. & Penman, D. (2011). Mindfulness: A practical guide to finding peace in a frantic world. London: Piatkus.
- Where
- 2 sites in United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Brain Health Activities, Cognition
Psychological and Lifestyle Factors That Predict Adherence of Multi-domain Interventions for Promoting Brain Health
Ageing is associated with a rising burden of neurological disorders, particularly dementia, which are now the leading cause of disability worldwide.
- Conditions
- Brain Health Activities, Cognition, Prevention, Cognitive Decline
- Trial name
- ToBrainHealth (NCT07387523)
- Testing
- Generic Lifestyle Education, ToBrainHealth Personalised Digital Intervention, ToBrainHealth Personalised Digital Intervention with Coaching
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut Guttmann
Care Giving Burden, Dementia
E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app
The goal of this clinical trial is to test whether a web-based application called the Pain Control Enhancement App (PACE-app) can support family caregivers in managing pain for their care recipients with dementia.
- Conditions
- Care Giving Burden, Dementia, Chronic Pain, Pain Management
- Trial name
- PACE-app (NCT07032350)
- Testing
- Web-based pain management support tool, Usual Pain Management Care
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Calorie Deficiency, Fasting
Effects of Calorie Restriction and Cold Stimuli on Health-related Indicators, Cognitive and Motor Functions
The goal of this clinical trial was to identify if duration of acute calorie restriction (CR)/fasting or combination CR with cold stimuli have any effects on mental and physical health-related markers, and to clarify if different…
- Conditions
- Calorie Deficiency, Fasting, Cold Exposure
- Trial name
- NCT05545943
- Testing
- 2-days of zero calorie restriction and whole-body cold-water immersion, 6-days of calorie restriction, 2-days of zero calorie restriction without whole-body cold-water immersion
- Where
- Lithuania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Anxiety, Depression
Child STEPS for Youth Mental Health in Maine Sustainability
The overarching goal of this project is to study the sustainability of MATCH-ADTC within community mental health clinics, to learn what is needed for evidence-based practices (EBPs) to take root and thrive within a public system.
- Conditions
- Anxiety, Depression, Trauma, Behavior Problems
- Trial name
- NCT03112304
- Testing
- MATCH-ADTC, TRAC
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Harvard University
Sleep, Well-Being (Psychological Flourishing)
Cognitive Training for Student Sleep and Wellness
This randomized control trial (RCT) explores two potential stress reduction interventions: a digital mindfulness program personalized for first year college students and a problem-solving based stress management program.
- Trial name
- NCT07350733
- Testing
- Equa, Coping Control
- Where
- 4 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Smoking, Bipolar Disorder
Web-Delivered Acceptance & Commitment Therapy for Smokers With Bipolar Disorder
This purpose of the study is to develop and test a new website to help people who have bipolar disorder quit smoking.
- Trial name
- WebQuit Plus (NCT02750904)
- Testing
- Experimental plus Nicotine Replacement Therapy, Control plus Nicotine Replacement Therapy
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- Fred Hutchinson Cancer Center
Cognitive Function
Radicle Clarity: A Study Assessing the Impact of Health and Wellness Products on Cognitive Function and Related Health Outcomes
A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on cognitive function and related health outcomes.
- Trial name
- NCT07148986
- Testing
- Clarity Active Product 1
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Depression
Cognitive Behavioral and Faith Fellowship to Improve Thy Health
Investigators will examine the efficacy of a faith-based depression intervention, in reducing symptoms of depression among African American adults in Wisconsin.
- Trial name
- CB-FAITH (NCT06292637)
- Testing
- Cognitive Behavioral Faith Fellowship to Improve Thy Health (CB-FAITH)
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of Wisconsin, Madison
Technology
Therapeutic Effectiveness of PARO Companion Robot for Elderly With Mild Cognitive Impairment/Dementia in Elderly Residential Setting: A Quasi-experimental Study
The main trial is a 2-group quasi-experimental trial of comparing the outcome indicators between joining and not joining the 10-week personal assistive robot (PARO) training program in residents with dementia or mild cognitive…
- Trial name
- NCT05404802
- Testing
- Experimental group intervention, Control group intervention
- Where
- 2 sites in Hong Kong
- Volunteers
- 37 people
- Sponsor
- The University of Hong Kong
Anxiety, Coping Skills
Building Cognitive Behavioural Skills With StoryBooks to Reduce Emotional Difficulties in Kindergarten Years
This research aims to ask (1) Are child and parent measures of coping skills, anxiety and other outcomes reliable (2) How feasible and acceptable is the proposed CB preventative program and protocol (3) Can a preliminary…
- Conditions
- Anxiety, Coping Skills, Socio-emotional Well-being
- Trial name
- B-READY (NCT07425951)
- Testing
- Cognitive Behavioural, Language
- Where
- Singapore
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University