Clinical trials: Cognitive Functions
Down Syndrome
Efficacy Study of Folinic Acid to Improve Mental Development of Children With Down Syndrome
The purpose of this study is to determine whether folinic acid can improve developmental quotient of young Down syndrome patients, given that these present signs of folate deficiency which are known to cause reversible…
- Trial name
- NCT00294593
- Testing
- folinic acid
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Institut Jerome Lejeune
Behaviors and Mental Disorders
Neurostimulation-enhanced Behavioral Remediation of Social Cognition in Schizophrenia
Social cognition concerns the understanding of how people think about others and how that, in turn, influences our behavior, feelings, and social interactions.
- Trial name
- NSOCOG (NCT03213600)
- Testing
- transcranial Direct Current Stimulation tDCS
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Colorectal Cancer, Breast Cancer
Momentum Project Heidelberg - Dealing Actively With a Cancerous Disease
The study, investigates the current physical activity promotion practices among physicians and nurses, as well as social norms toward physical activity during treatment among cancer patients and among physicians and nurses who…
- Conditions
- Colorectal Cancer, Breast Cancer, Prostate Cancer, Physicians
- Trial name
- NCT02678832
- Volunteers
- 2,200 people
- Sponsor
- Heidelberg University
Post-Traumatic Stress Disorders, Traumatic Brain Injury
Rural Veterans With Post-traumatic Stress Disorder (PTSD) And Comorbid Mild Traumatic Brain Injury (TBI): A Feasibility Study
This study is being conducted to understand whether training in tasks that require perceiving and thinking about things, or cognition, can improve memory in veterans who have been exposed to a blast explosion and have TBI and…
- Trial name
- NCT01278316
- Testing
- Control, Cognitive Training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Michael E. DeBakey VA Medical Center
The Effectiveness of Precision Nursing Intervention Program on Cognitive Function、Sleep Quality and Emotional State of Frail Femal Elderly in the Community
Precision Nursing Intervention Program on Cognitive Function、Sleep Quality and Emotional State of Frail Female Elderly
Background: Taiwan's community population is aging rapidly, and women in the aging community account for the majority of frail elderly.In the process of aging, you must face changes in cognitive function, sleep disorders, and…
- Trial name
- NCT04902716
- Testing
- Design course
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Alzheimer Disease
Georgia Memory Net Anti-Amyloid Monoclonal Antibody Registry
The purpose of this registry is to compile information on patients who are receiving FDA-approved anti-amyloid mAbs in the course of their clinic visits in the Emory Cognitive Neurology Clinic and in Georgia Memory Net Memory…
- Trial name
- NCT05999084
- Testing
- Anti-amyloid Monoclonal Antibodies (mAbs), Standard of Care
- Where
- 8 sites in United States
- Volunteers
- 735 people
- Sponsor
- Emory University
Stroke, Coronary Artery Disease
Cerebral Artery Stenosis, Coronary Artery Disease and Arrhythmia
There are many reports about the association of coronary artery disease (CAD) and cerebral artery stenosis (CAS), which had been proved to induce stroke and cognition decline after the revascularization including coronary bypass…
- Conditions
- Stroke, Coronary Artery Disease, Arrhythmia
- Trial name
- NCT00247533
- Testing
- Digital subtraction angiography and 24-hour simultaneous recorder of electrocardiograph
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Far Eastern Memorial Hospital
Major Depressive Disorder (MDD), Adolescent Depression
Predictors of rTMS and Group Therapy Efficacy in Adolescent Depression
This study aims to identify baseline predictors of treatment efficacy in adolescents with Major Depressive Disorder (MDD) undergoing a combined intervention of repetitive transcranial magnetic stimulation (rTMS) and group…
- Trial name
- NCT07283419
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Group Cognitive Behavioral Therapy (CBT)
- Where
- China
- Volunteers
- 163 people
- Sponsor
- The First Hospital of Hebei Medical University
Ovarian Cancer, Cognitive Decline
Predictors of Cognitive Decline and Delirium in Older Women With Ovarian Cancer
Cognitive decline and delirium are common geriatric syndromes that adversely affect treatment adherence, functional independence, quality of life, and survival in older adults with cancer.
- Conditions
- Ovarian Cancer, Cognitive Decline, Delirium
- Trial name
- CROWN (NCT07716800)
- Volunteers
- 205 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Balance, Cognitive Functions
Effects of Simultaneous Versus Sequential Motor-cognitive Task Training on Balance and Coordination Among Elderly Individuals
A randomized control trial will be done on elderly individuals in Community Homes of Rawalpindi/Islamabad. Motor-cognitive impairments impact the life of elderly individuals.
- Trial name
- NCT06967844
- Testing
- Simultaneous motor-cognitive task training, Sequential motor-cognitive task training
- Where
- Pakistan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Opioid Use Disorder, Chronic Pain
Digital Treatment for Chronic Pain and Addiction in Veterans With Opioid Use Disorder Receiving Buprenorphine
Chronic pain is common in individuals with opioid use disorder (OUD) and the first-line treatment, Medication for OUD (MOUD), does not address the considerable functional impairments associated with chronic pain.
- Trial name
- NCT07361432
- Testing
- Integrating the Management of Pain and Addiction via Collaborative Treatment (IMPACT), Enhanced Treatment as Usual (ETAU)
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- VA Office of Research and Development
Focal Brain Injury, Cognition
Cognitive Function Assessment in Patients With Focal Brain Injury
This research relates to the study of cognitive deficits related to various focal brain lesions and their localizations in the brain.
- Trial name
- LESCOG (NCT04182087)
- Testing
- Cognitive tasks
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Grenoble
Schizophrenia
Efficiency of the French Translation Social Cognition and Interactive Training (SCIT)Program
Social cognition and interaction training (SCIT), a group-based treatment that aims to improve both processing social information and functioning, may be an effective treatment for enhancing the social skills of people with…
- Trial name
- SCIT-VF (NCT02667834)
- Testing
- Social Cognition and Interaction Training (SCIT), therapeutic education program (ETP)
- Where
- France
- Volunteers
- 103 people
- Sponsor
- Hôpital le Vinatier
Multiple Sclerosis
Effect of Training With Wireless Lightning Reaction Systems on Cognitive Functions in Individuals With Multiple Sclerosis
When the literature is examined, balance disorders, walking disorders and cognitive problems are frequently observed in Multiple Sclerosis(MS) patients.
- Trial name
- NCT06874764
- Testing
- Wireless Lighting Reaction System Training(Agility plus Cognitive)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ege University
Cognition Disorders
Brain Imaging and Mental Disorders of Aging Intervention
The goal of this project is to determine if a cholinesterase inhibitor is more effective than placebo in delaying cognitive and brain functional decline in people at risk for Alzheimer's disease.
- Trial name
- NCT00267163
- Testing
- donepezil
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- National Institute on Aging (NIA)
Schizophrenia, Schizophreniform Disorders
Benefits of Combining MCT With CR in the Recovery of Patients With Psychotic Spectrum Disorders
The goal of this clinical trial is to compare the efficacy of combined REHACOP + MCT alone in persons with nonaffective psychotic disorder in terms of recovery.
- Conditions
- Schizophrenia, Schizophreniform Disorders, Delusional Disorder, Brief Psychotic Disorder
- Trial name
- CR+MCTp (NCT06423651)
- Testing
- Cognitive Remediation (REHACOP), Metacognitive Training (MCT)
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Universitat Autonoma de Barcelona
Hearing Loss, Bilateral Sensorineural
Cochlear Implantation and Social Outcomes
The goal of this clinical trial is to learn if hearing devices, like cochlear implants, affect social and cognitive function of older adults.
- Trial name
- NCT07584837
- Testing
- Cochlear implant
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Healthy
Effects of Breakfast Glycaemic Index on Cognition in Earlier or Later Chronotypes.
High glycaemic index (GI) breakfasts resulting in sharp rises in blood glucose may adversely affect memory and attention, particularly in the late postprandial phase (i.e., 120-180 minutes after breakfast).
- Trial name
- GlyCoBrainIn1 (NCT06916039)
- Testing
- immediate verbal memory after high GI breakfast, immediate verbal memory after low glycemic index breakfast
- Where
- Germany
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Anette Buyken
Diabetes Mellitus, Type 2, Cognitive Dysfunction
Risk Factors for Type 2 Diabetes Mellitus With Cognitive Impairment: a Cohort Study
The aim of this study was to analyze the risk factors for the development of type 2 diabetes mellitus (T2DM) with mild cognitive impairment (MCI) and its pathogenesis associated with gut microbiota.
- Conditions
- Diabetes Mellitus, Type 2, Cognitive Dysfunction, Gut Microbiota
- Trial name
- NCT05728567
- Testing
- whether the participants had T2DM
- Volunteers
- 3,820 people
- Sponsor
- Peking University
Cognitive Impairment, Pulmonary Rehabilitation
Does Cognitive Status Affect Pulmonary Rehabilitation Gains?
Pulmonary rehabilitation program with aerobic and strengthening trainings for 3 months will be applied to the candidates for lung transplantation.
- Trial name
- NCT03740867
- Testing
- Pulmonary rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medipol University Hospital