Clinical trials: Cognitive Functioning
Schizophrenia, Schizoaffective Disorder
Effect of Varenicline on Cognitive Function in Cigarette Smokers With Schizophrenia
Smokers with schizophrenia have more difficulties quitting smoking than smokers without a mental disorder. Varenicline (Champix) is a new stop smoking medication with a unique mechanism of action.
- Trial name
- NCT01093365
- Testing
- Varenicline
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Insomnia, Cognitive Impairment
The Effect of Aromatherapy on Sleep and Cognitive Level in the Elderly
This research aims to investigate the effect of aromatherapy on sleep duration, sleep quality, falling asleep time and cognitive functions of elderly individuals in the short term and to improve the general health status and…
- Conditions
- Insomnia, Cognitive Impairment, Elderly
- Trial name
- NCT06208800
- Testing
- Blend Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medipol University
Stroke Patients
Predicting Language Recovery in Acute Stroke Patients in the Neurovascular Intensive Care Unit: An Exploratory Study With the Core Assessment of Language Processing.
Introduction: Stroke affects one person every 4 minutes in France (i.e. more than 140,000 new cases per year) resulting in cognitive and motor disorders.
- Trial name
- PREDICT-CALAP (NCT06817642)
- Testing
- Data recovery from language and cognitive assessment
- Where
- France
- Volunteers
- 570 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Cognitive Impairment
Combining Cognitive and Treadmill Training on Cognition and Walking Performance in Stroke With Cognitive Impairment
Post-stroke cognitive impairment is common in stroke survivors. Cognitive function is related to walking ability. The dual task walking is required for daily activities, however, such ability is even more challenging than single…
- Trial name
- NCT04545138
- Testing
- cognitive training combine treadmill training, Treadmill training
- Where
- Taiwan
- Volunteers
- 8 people
- Sponsor
- National Yang Ming Chiao Tung University
Alzheimer Disease, Mild Cognitive Impairment
Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease
In this research study we want to learn more about the effects of non-invasive brain stimulation on memory and brain-network function in cognitively unimpaired older adults and in patients with amnestic mild cognitive impairment…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Logopenic Progressive Aphasia, Amnestic Symptoms
- Trial name
- NCT06538311
- Testing
- Active rTMS
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cognitive Function, E-sports Performance
Visual Training Effects in Esports Players
This randomized controlled study aims to investigate the acute effects of a single session of web-based visual training on balance, reaction time, and cognitive function in professional e-sports players.
- Conditions
- Cognitive Function, E-sports Performance, Reaction Time, Balance
- Trial name
- NCT07570693
- Testing
- Web-Based Visual Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Negative Symptoms in Schizophrenia, Cognition Function
tACS to Improve Negative Symptoms & Cognition in Long-term Hospitalized Schizophrenia Patients.
This study aims to evaluate the efficacy of transcranial alternating current stimulation (tACS) on negative symptoms and cognitive function in long-term hospitalized patients with schizophrenia.
- Trial name
- NCT07074704
- Testing
- Hi-tACS
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tongji University
Cognitive Impairment
The Mental Activity and eXercise Trial for Seniors
The primary objective of this study is to conduct a randomized, controlled trial to determine whether engaging in mental activity or exercise, either alone or in combination, improves cognitive function in non-demented, inactive…
- Trial name
- MAX (NCT00522899)
- Testing
- Group 1, Group 2, Group 3
- Where
- 2 sites in United States
- Volunteers
- 126 people
- Sponsor
- University of California, San Francisco
COVID-19, Brain Fog
Transcranial Ultrasound Stimulation for Cognitive Function Modulation in Patients With Post COVID-19 Brain Fog
This study aims to investigate whether a specific brain region mediates the cognitive deficit in long COVID brain fog, and whether targeted modulation of this region can improve cognition.
- Conditions
- COVID-19, Brain Fog, Long COVID, Transcranial Ultrasound Stimulation
- Trial name
- NCT07154199
- Testing
- real transcranial ultrasound stimulation
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Xuanwu Hospital, Beijing
Complex Regional Pain Syndromes
Physical and Psychological Changes in CRPS Patients Undergoing Multimodal Rehabilitation
The goal of this clinical trial is to learn about cognitive changes during rehabilitation in CRPS patients. The main questions it aims to answer are: What are the cognitive changes in CRPS? Do cognitive functions change during…
- Trial name
- NCT05696587
- Testing
- Multimodal rehabilitation
- Where
- Poland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Breast Cancer, Cognitive/Functional Effects
Cognitive Function in Postmenopausal Women With Breast Cancer Receiving Hormone Therapy on Clinical Trial IBCSG-1-98
RATIONALE: Studying cognitive function, such as thinking, attention, concentration, and memory, in postmenopausal women receiving hormone therapy for breast cancer may help improve quality of life and the ability to plan…
- Conditions
- Breast Cancer, Cognitive/Functional Effects, Fatigue, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT00343616
- Testing
- cognitive assessment, fatigue assessment and management, psychologic distress
- Where
- 12 sites in Australia, Belgium and 4 more
- Volunteers
- 135 people
- Sponsor
- ETOP IBCSG Partners Foundation
Sleep Disturbances
Bonafide Sleep Supplement for Menopausal Women With Impaired Sleep
This open-label study evaluated whether a daily dietary sleep supplement could improve sleep and related daytime functioning in menopausal women aged 40 to 65 with impaired sleep.
- Trial name
- NCT07839299
- Testing
- S-Adenosyl Methionine (SAMe), Propyl Gallate, Gamma-Aminobutyric Acid (GABA), L-Theanine, and Magnesium Glycinate
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bonafide Health
Thyroid, Carotid Doppler
Effect of Head Position During Thyroidectomy on Postoperative Cognitive Functions
The aim of our study is to observe the effect of head-neck position of patients scheduled for thyroidectomy, on carotid artery blood flow, regional cerebral oxygen saturation measured using near-infrared spectroscopy technology…
- Conditions
- Thyroid, Carotid Doppler, Cerebral Perfusion
- Trial name
- NCT04830293
- Testing
- Carotis Doppler Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Tobacco Use Disorder, Schizophrenia
Combining rTMS With Varenicline to Prevent Smoking Lapse in Schizophrenia
Tobacco smokers with schizophrenia are known to be resistant smokers, with high rates of smoking and inability to quit in the long-term, often related to smoking relapse.
- Conditions
- Tobacco Use Disorder, Schizophrenia, Cognitive Functioning, Craving
- Trial name
- NCT03497299
- Testing
- Active rTMS (20Hz)
- Sponsor
- Centre for Addiction and Mental Health
Mild Cognitive Impairment (MCI)
Effects of Transcranial Temporal Interference Stimulation on Cognitive Function in Mild Cognitive Impairment
To explore the effects of transcranial temporal interference stimulation (tTIS) on cognitive function and dual-task walking performance, as well as its underlying neuroimaging mechanisms, in individuals with mild cognitive…
- Trial name
- TIS-MCI (NCT07519798)
- Testing
- Active Temporal Interference Stimulation (TIS)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai University of Sport
Long COVID-19 Syndrome, COVID 19
Evaluating the Impact of a Functional and Cognitive Strategy in Patients With Long Covid-19
This study aims to evaluate the impact of a functional and cognitive rehabilitation strategy compared to evidence-based informational messages, on functional capacity, cognitive abilities, quality of life, and disease progression…
- Conditions
- Long COVID-19 Syndrome, COVID 19, Noncommunicable Disease, Hypertension
- Trial name
- NCT06871293
- Testing
- Functional and cognitive rehabilitation strategy, Evidence-Based Informational Support
- Where
- Colombia
- Volunteers
- 374 people
- Sponsor
- Fundación Cardioinfantil Instituto de Cardiología
Cognitive Deficits, Depression
Attentional Bias Modification Through Eye-tracker Methodology (ABMET)
Cognitive biases are a hallmark of depression but there is scarce research on whether these biases can be directly modified by using specific cognitive training techniques.
- Conditions
- Cognitive Deficits, Depression, Alteration of Cognitive Function
- Trial name
- ABMET (NCT02847793)
- Testing
- Gaze training
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Universidad Complutense de Madrid
Caffeine
The Effects of e+Shots Energy Beverage on Mental Energy
The aim of the research project is to determine the changes in motivation to perform mental and physical tasks, feelings of vigor and fatigue, mental task vigilance and fine motor function after consumption of a commercially…
- Trial name
- NCT03850275
- Testing
- Intervention/treatment
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Clarkson University
Cerebrovascular Circulation
MRI Biomarkers and Exercise
The overall goal of observational study is to examine the age-related and habitual exercise training status-related differences in structural and functional changes in the human brain, detected by magnetic resonance (MR) imaging.
- Trial name
- NCT02729428
- Testing
- MRI
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison