Clinical trials: Cognitive Flexibility
Orthorexia Nervosa
Effects of tDCS on Cognitive Flexibility and EEG Oscillations in Orthorexia Nervosa
Orthorexia Nervosa (ON); is a condition characterized by individuals being overly focused on healthy eating habits, constantly checking and classifying the foods they will consume.
- Trial name
- NCT07141979
- Testing
- Active tDCS
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Autism Spectrum Disorder (ASD)
Acceptance and Commitment Therapy for Parents of Children With ASD: Effects on Cognitive Fusion, Stigma, and Mindfulness
The goal of this intervention is to evaluate whether Acceptance and Commitment Therapy (ACT) can improve psychological well-being among parents of children with Autism Spectrum Disorder (ASD) in Saudi Arabia.
- Trial name
- ACT-CFSM (NCT07582627)
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- University of Jazan
Endotoxemia, Inflammation
Short-Chain Fatty Acids in Lypopolysaccharide-Induced Inflammation and Executive Function
Short-chain fatty acids (SCFAs) are substances produced by gut bacteria when they ferment dietary fiber. They can act as signals between the gut and the brain and may help regulate the body's immune and stress responses.
- Conditions
- Endotoxemia, Inflammation, Executive Function (Cognition)
- Trial name
- NCT07713641
- Testing
- Short-Chain Fatty Acid Colon-Delivery Capsules, Lipopolysaccharide (LPS)
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Pain, Knee Pain Chronic
Cognitive Flexibility Training for Persistent Pain: Neuroimaging Pilot (COFLEX-i)
To determine whether a 5-week computer-based cognitive training intervention results in changes in resting-state functional connectivity (rsFC) within the brain networks.
- Conditions
- Chronic Pain, Knee Pain Chronic, Hip Pain Chronic, Back Pain
- Trial name
- COFLEX-i (NCT03720821)
- Testing
- Cognitive Training + fMRI
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Executive Function
The Order Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study
Executive function is a high-level cognition which plays an important role in our life. Meta-analysis study has demonstrated that acute exercise could improve executive function.
- Trial name
- NCT05314699
- Testing
- resistance-aerobic exercise, RA, aerobic-resistance exercise, AR
- Where
- Taiwan
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Anxiety Disorders, Mindfulness
The Impact of Mindfulness-Based Psychoeducation on Perceived Stress, Intolerance of Uncertainty, and Cognitive Flexibility in Patients With Anxiety Disorders
Mindfulness-based interventions, which cultivate the capacity to remain present with difficult thoughts and emotions and to maintain psychological well-being in the face of such challenges, have been shown to facilitate positive…
- Conditions
- Anxiety Disorders, Mindfulness, Perceived Stress, Intolerance of Uncertainty
- Trial name
- Anxiety (NCT07299045)
- Testing
- Mindfulness-Based Psychoeducational Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Aydin Adnan Menderes University
Languages
Impact of Theta Burst Stimulation Over the Left DLPFC on Language Switching
The purpose of this study is to investigate whether theta burst stimulation (TBS) over the left dorsolateral prefrontal cortex (DLPFC) influences language switching and cognitive flexibility.
- Trial name
- NCT03148470
- Testing
- intermittent theta burst stimulation (iTBS), continuous theta burst stimulation (cTBS)
- Where
- Switzerland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Jean-Marie Annoni
Obsessive-Compulsive Disorder
Unique Electroencephalography (EEG) Markers of Habit Behaviors in Obsessive-Compulsive Disorder (OCD)
This study focuses on explaining the occurrence and development of compulsive behaviors from habit hypothesis. Investigators will study both OCD patients and healthy individuals using Hardwick's forced-response time task(2019)…
- Trial name
- NCT06882902
- Testing
- habit formation training
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Child Development, Executive Functions (EF)
Sharing Tales That Teach: Shared Picturebook Reading for Early Childhood Emotional and Cognitive Development
Sharing Tales That Teach is a randomised study of a shared picturebook reading programme for 4- to 5-year-old children and their primary caregivers.
- Conditions
- Child Development, Executive Functions (EF), Emotion Regulation
- Trial name
- STTT (NCT07666802)
- Testing
- Emotion-Focused Shared Picturebook Reading, Standard Dialogic Picturebook Reading
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Greenwich
Positive Mood States, Negative Mood States
The Impact of Twin Hearts Meditation on Mood, Cognitive Functioning, and EEG Dynamics
The goal of this clinical trial is to examine the impact of a specific guided meditation (Twin Hearts Meditation; THM) on cognitive functioning and EEG dynamics in experienced and inexperienced meditators.
- Conditions
- Positive Mood States, Negative Mood States, Cognitive Processing Speed, Cognitive Flexibility
- Trial name
- NCT07005830
- Testing
- Twin Hearts Meditation
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- NeuroMeditation Institute
Dysexecutive Syndrome
Modulation and Assessment of Mental Flexibility in Dysexecutive Brain Patients
This project aims to (1) define and characterize brain networks of cognitive flexibility amongst patients with frontal lesions; (2) quantify the effects of ecological cognitive trainings and brain stimulation on behavioral…
- Trial name
- MODEX (NCT04253522)
- Testing
- Cognitive training
- Where
- France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Toulouse
Active tDCS, Sham tDCS
Neuromodulation Augmented Cognitive Training to Improve Cognitive Flexibility in Anorexia Nervosa
The purpose of the study is to evaluate the use of a new brain stimulation tool called transcranial direct current stimulation (tDCS). tDCS is a new technique used to stimulate the brain.
- Trial name
- NCT03647943
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Sponsor
- University of Minnesota
Cognitive Assessment, Working Memory
Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.
The proposed project will evaluate the synergistic effects of a nutritional formulation, 'Think Tank' on cognitive performance following exposure to a psychological and physical stressor.
- Conditions
- Cognitive Assessment, Working Memory, Executive Function (Cognition), Sustained Attention
- Trial name
- NCT07319117
- Testing
- Skoshify 'Think Tank' Formulation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Anxiety Disorders, Depressive Disorder
Study on Mental Health Promoting Effects of Natural Psychotherapy for Adolescents
This randomized controlled trial aims to evaluate the efficacy of a universal intervention based on Natural Psychotherapy in reducing anxiety and depressive symptoms among primary and middle school students.
- Conditions
- Anxiety Disorders, Depressive Disorder, Mental Health
- Trial name
- NP-A-MHP (NCT07639476)
- Testing
- Multi-modal Nature-based Meditation, Intervention diary
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Beijing HuiLongGuan Hospital
Obesity, Body Weight
Metabolic and Bio-behavioral Effects of Following Recommendations in the Dietary Guidelines for Americans
This study, at the Western Human Nutrition Research Center (WHNRC), will focus on whether or not achieving and maintaining a healthy body weight is the most important health promoting recommendation of the Dietary Guidelines for…
- Trial name
- DGA4ME (NCT04293224)
- Testing
- DGA Mediterranean diet pattern, energy balance, DGA Mediterranean diet pattern, negative energy balance, TAD diet pattern, negative energy balance
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Cognitive Flexibility
Modulation of Cognitive Flexibility by Tyrosine Depletion and Transcranial Direct Current Stimulation
The dorsolateral prefrontal cortex (dlPFC) and dopamine (DA) have been implicated in the control of cognitive flexibility. However, while a great deal of what it is know regarding a causative relationship between cognitive…
- Trial name
- NCT03462303
- Testing
- Anodal tDCS and tyrosine depleted drink, Anodal tDCS and balanced drink
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Psychological Flexibility, Emotional Distress
Acceptance and Commitment Therapy on Psychological Flexibility, Values, and Well-Being: A Single-Case Experimental Study
The goal of this clinical trial is to evaluate the effects of a brief Acceptance and Commitment Therapy (ACT)-based group intervention on psychological flexibility, values-based functioning, and psychological well-being in…
- Conditions
- Psychological Flexibility, Emotional Distress, Psychological Well-Being, Experiential Avoidance
- Trial name
- ACT-UNIVALLE (NCT07620483)
- Testing
- Acceptance and Commitment Therapy (ACT)-Based Brief Group Intervention
- Where
- Colombia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Psychosis, Cannabis Use Disorder
Testing the Efficacy of the Cannabis Clinic for Patients With Psychosis (CCP) Intervention for Cannabis Use Reduction/Cessation in Patients With First Episode Psychosis (FEP)
People suffering from psychosis who use cannabis experience more relapses, long and compulsory admissions, with huge costs to the individual, families and health services.
- Conditions
- Psychosis, Cannabis Use Disorder, First Episode Psychosis (FEP)
- Trial name
- CCP RCT (NCT07245212)
- Testing
- CCP Intervention
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- King's College London
Stress
The Effect of a Stress Coping Training Program for University Students
This randomized controlled study examines the effects of a structured stress coping training program on perceived stress, cognitive flexibility, psychological resilience, and burnout among university students.
- Trial name
- SCTP (NCT07454109)
- Testing
- Structured Stress Coping Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy Preschoolers
Fundamental Movement Skills Training Improves Executive Functions in Preschoolers
This randomized controlled trial investigated the effects of a 12-week structured fundamental movement skills (FMS) training program on executive functions in 34 healthy preschoolers aged 5-6 years.
- Trial name
- FMS-EF-RCT (NCT07725354)
- Testing
- Fundamental Movement Skills Training, Regular Physical Activity
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Xi'an Physical Education University