Clinical trials: Cognitive Fatigue
Post COVID-19, Cognitive Dysfunction
Multimodal Investigation of Post COVID-19 in Females
The purpose of this study is to investigate the effects of transcutaneous vagus nerve stimulation (t-VNS) on Long Covid symptoms in females and to identify factors influencing susceptibility and recovery-particularly in the…
- Trial name
- NCT05225220
- Testing
- Parasym Device (of Parasym Ltd, UK) using Transcutaneous Vagus Nerve Stimulation (t-VNS)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Anxiety Disorder, Cognitive/Functional Effects
Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer
RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical…
- Conditions
- Anxiety Disorder, Cognitive/Functional Effects, Colorectal Cancer, Depression
- Trial name
- CHALLENGE (NCT00819208)
- Testing
- exercise intervention, counseling intervention, educational intervention
- Where
- 47 sites in United States, Australia and 4 more
- Volunteers
- 889 people
- Sponsor
- Canadian Cancer Trials Group
Cancer-related Cognitive Difficulties, Cancer-related Problem/Condition
Modafinil to Improve Fatiguability
Cancer-related fatigue (CRF) and cancer-related cognitive impairment (CRCI) are among the most commonly reported disabling symptoms experienced by patients with advanced cancer.
- Conditions
- Cancer-related Cognitive Difficulties, Cancer-related Problem/Condition, Fatigue
- Trial name
- MODIFY (NCT05333250)
- Testing
- Modafinil
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ottawa Hospital Research Institute
Iron Status
The Relationship Between Iron Status, Cognitive Performance, Subjective Mood and Fatigue in Women of Reproductive Age.
Iron deficiency is the most prevalent nutritional deficiency worldwide with one in four estimated to be affected by iron deficiency anaemia.
- Trial name
- NCT04257669
- Where
- United Kingdom
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Hodgkin Lymphoma, Fatigue
CBT on Fatigue in Survivors of Hodgkin Lymphoma
Background: Cancer-related fatigue is one of the most common patient-reported impairments in survivors of Hodgkin lymphoma and is associated with adverse effects on psychological well-being and everyday life including family…
- Trial name
- NCT03968250
- Testing
- Cognitive Behavioral Therapy for Treating Fatigue
- Where
- 2 sites in Germany
- Volunteers
- 17 people
- Sponsor
- University of Leipzig
Cognitive Function, Balance Impairment
Effects of Action Observation Therapy in Geriatric Individuals
This randomized controlled trial aimed to investigate the effects of Action Observation Therapy (AOT) on cognitive function, balance, fatigue, and functional capacity in geriatric individuals.
- Conditions
- Cognitive Function, Balance Impairment, Fatigue, Aging
- Trial name
- NCT07418970
- Testing
- Action, Action Observation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Cancer-related Fatigue, Cancer-related Cognitive Impairment
Reducing Cancer Side-effects With Systematic Light Exposure
The main purpose of this interdisciplinary proposal is to conduct two randomized controlled trial (RCT) of the efficacy of self-administered systematic light exposure (Bright White Light (BWL)), an innovative, low cost, and low…
- Trial name
- LYS (NCT02661308)
- Testing
- Litebook
- Where
- Denmark
- Volunteers
- 108 people
- Sponsor
- Aarhus University Hospital
Social Media Addiction
4-STEP Training Program for Social Media Addiction, Cognitive Fatigue, Psychological Distress, Academic Burnout and Procrastination Among Students
This study aims to evaluate the effectiveness of a structured four-step training program for reducing social media addiction and its associated psychological and academic difficulties among school and university students.
- Trial name
- 4-STEP-TPS (NCT07821489)
- Testing
- 4-STEP-TPS
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Cognitive Function Assessment, Mental Fatigue
Effects of Short-Term Creatine Supplementation on Cognitive Function in Healthy Young Adults
This study examined whether short-term creatine supplementation affects cognitive function in healthy young adults. Participants were randomly assigned to take either creatine monohydrate or a placebo for 10 days.
- Trial name
- NCT07867041
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Neoplasms, Fatigue
COMPANION: A Couple Intervention Targeting Cancer-related Fatigue
Chronic cancer-related fatigue (CCRF) is a disturbing condition that persists in up to 25% of cancer patients after completion of treatment.
- Trial name
- COMPANION (NCT05636696)
- Testing
- Samen Minder Moe (Dutch intervention name)
- Where
- 2 sites in Netherlands
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mariët Hagedoorn
Parkinson Disease(PD)
Central and Peripheral Fatigue in Individuals With Parkinson's Disease - Evaluation and Training
Fatigue is one of the most common symptoms in individuals with Parkinson's Disease (PD). Past research indicated that more than half of the individuals with PD demonstrated fatigue symptom.
- Trial name
- NCT01971528
- Testing
- Electronic muscle stimulator, Muscle strength training
- Where
- Taiwan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Heart Failure, Insomnia
Cognitive Behavioral Therapy for Insomnia in Stable Heart Failure
The purpose of this exploratory developmental study is to test the feasibility, acceptability, and preliminary efficacy of cognitive behavioral therapy for insomnia (CBT-I) among adults who have stable Heart Failure.
- Conditions
- Heart Failure, Insomnia, Cardiomyopathy
- Trial name
- CBTI-HF (NCT02827799)
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Heart Failure Self-Management Education
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Yale University
Nutrition Processes
Effects of Nutraperf Consumption in Runners
Exercise has numerous health benefits. Nevertheless, when exercise duration is ~45 min or longer and intensity moderate to intense, it may induce different troubles, for example: hypoglycemia, peripheral and central fatigue…
- Trial name
- NCT00799630
- Testing
- Carbohydrate drink
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Lescuyer Laboratory
Mental Fatigue
Brain Oxygenation Marker for Cognitive Function in Healthy Adults
This study aims to identify a cortical oxygenation marker for cognitive function using functional Near Infrared Spectroscopy in healthy adults.
- Trial name
- NCT05559034
- Testing
- Cognitive intervention
- Where
- Switzerland
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Fatigue, Reaction Time
Effects of Physical and Cognitive Fatigue on Reaction Time and Depth Perception in Adolescents
This study investigates how physical fatigue, cognitive fatigue, and a combination of both affect reaction time and depth perception in adolescents.
- Conditions
- Fatigue, Reaction Time, Depth Perception
- Trial name
- NCT07855406
- Testing
- Physical Fatigue Protocol, Cognitive Fatigue Protocol, Combined Fatigue Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- AslanAhmetKaan
Allogeneic Stem Cell Transplantation, Exercise Intervention
Cognition in Allogeneic Stem Cell Transplanted Patients and Sports
Studies suggest that patients with hematological malignancies undergoing allogeneic hematopoietic stem cell transplantation (HSCT) are at risk for cognitive decline and long-term cognitive dysfunction.
- Trial name
- CaSpo (NCT02533947)
- Testing
- Exercise, Control
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Inflammation, Fatigue
Effects of Riluzole on CNS Glutamate and Fatigue in Breast Cancer Survivors With High Inflammation
The goal of the proposed research is to determine whether riluzole, a drug that increases glutamate reuptake, will decrease central nervous system (CNS) glutamate in breast cancer survivors with increased inflammation and…
- Trial name
- NCT02796755
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Attention, Memory
Polyunsaturated Fatty Acids (PUFA) Status and Cognitive Function in Healthy Young Adults
To date, the relationship between omega-3 polyunsaturated fatty acids (n-3 PUFAs) in cognitively intact individuals has only been examined in a limited number of studies; it is at present unknown whether supplementation with n-3…
- Conditions
- Attention, Memory, Mood, Mental Fatigue
- Trial name
- NCT01075958
- Where
- United Kingdom
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Traumatic Brain Injury, Fatigue
Brain and Gut Plasticity in Mild TBI or Post-acute COVID Syndrome Following Growth Hormone Therapy
Patients with a history of mild traumatic brain injury (mTBI) or post acute sequelae of SARS-CoV-2 (PASC) and abnormal growth hormone secretion, as measured by glucagon stimulation test, will be treated with replacement growth…
- Conditions
- Traumatic Brain Injury, Fatigue, Cognitive Impairment, COVID-19
- Trial name
- NCT03554265
- Testing
- Somatropin
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Healthy
Effects of Sage Extracts on Cognitive Function During Aerobic Exercise
Extracts of sage have been reported to interact with central nervous system (CNS) mechanisms relevant to cognitive performance but, to date, no trial has clearly demonstrated the possible effects in healthy individuals in…
- Trial name
- NCT04804657
- Testing
- Sage extracts Cognivia
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Burgundy