Clinical trials: Cognitive Development
Autism Spectrum Disorders
A Randomized, Controlled Trial of Intranasal Oxytocin as an Adjunct to Behavioral Therapy for Autism Spectrum Disorder
This 3-year study is a trial of cognitive behavioral therapy (CBT), with or without oxytocin (OT) augmentation, in young adults with autism spectrum disorders.
- Trial name
- NCT01914939
- Testing
- Oxytocin, Social Skills focused CBT, Stress management/relaxation training
- Where
- 2 sites in United States
- Volunteers
- 92 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder, Anxiety
Effect of Cognitive Behavioural Therapy (CBT) for Children With Autistic Spectrum Disorders
Cognitive Behavioural Therapy is an effective intervention program for children with High-Functioning Autistic Spectrum Disorder to remediate anxiety issues.
- Trial name
- NCT01031511
- Testing
- Cognitive Behavioural Therapy, Social Recreational
- Where
- Singapore
- Volunteers
- 73 people
- Sponsor
- National Healthcare Group, Singapore
Gambling
Development and Validation of a Mindfulness Intervention for Problem Gambling: An Exploratory Study
In recent years, mindfulness meditation has been shown to be a promising approach for alleviating emotional distress associated with chronic medical and psychiatric conditions and in reducing relapse following treatment for…
- Trial name
- NCT00495261
- Testing
- Mindfulness-enhanced cognitive behavioural therapy (MCBT), relaxation-enhanced cognitive behavioural therapy (RCBT)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Centre for Addiction and Mental Health
Kindergarten Children
Board Games at Kindergarten (5 Years Old) to Improve Cognitive and Emotional Processes
Cognitive (i.e. executive functions, memory) and socio-emotional (i.e. affection recognition) processes emerges at first years. These processes have been frequently related to adequate academic performance in the scientific…
- Trial name
- NCT06304454
- Testing
- Board game intervention
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Brain In Game scientific-technical service
Cognitive Development After Pediatric Live Transplantation
Cognitive Development After Pediatric Liver Transplantation
The purpose of this study is to investigate the cognitive performance after pediatric live transplantation.
- Trial name
- NCT03778983
- Where
- China
- Volunteers
- 130 people
- Sponsor
- RenJi Hospital
Schizophrenia
Metacognitive Intervention for Individuals With Severe Mental Disorders
The overall aim of this study was to develop a meta-cognitive group intervention in order to apply it and to understand and distinguish the components that influence participation among people with schizophrenia
- Trial name
- NCT05556941
- Testing
- Metacognitive Group Intervention, Occupational therapy standard care
- Volunteers
- 84 people
- Sponsor
- University of Haifa
Schizophrenia, Psychosis
Social Cognitive Training for Psychosis: Treatment Development
The primary aim of this proposal is to develop, refine, manualize and assess the feasibility and preliminary efficacy of a brief, narrowly-focused social cognitive intervention for individuals with psychosis.
- Trial name
- NCT01579422
- Testing
- social cognitive training
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Yale University
Neurodevelopmental Disorders, Motor Skills Disorders
Motor Development and Early Predictors of Psychomotor Outcomes in Preterm and Term Infants Assessed by MOS-R and Caregiver Questionnaire at 18 and 36 Months
This study examines how early motor behavior in infants relates to their later psychomotor development. Researchers will observe both preterm and full-term infants during the first months of life, using video-based assessments to…
- Conditions
- Neurodevelopmental Disorders, Motor Skills Disorders, Infant, Premature Development, Infant, Term Development
- Trial name
- NCT07296003
- Testing
- Vojta method
- Where
- 3 sites in Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Autism Spectrum Disorder
Metabolic Processes in Adults and Adolescents With Autism Spectrum Disorder
The objective of this study is to gain preliminary information and knowledge on metabolic profile in ASD. The benefit of this study will be to expand our insight of the potential relationship in metabolic processes and…
- Trial name
- ASD (NCT02733120)
- Testing
- stable isotope infusion
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Infant Nutrition, Cognitive Development
Efficacy of a Nutrient Blend in Improving Neurocognitive and Behavioral Outcomes in Infants: a Randomized, Controlled, Intervention Study
The purpose of this study is to demonstrate the efficacy of the nutrient blend in a starter infant formula (IF) and follow up infant formula (FUF) in improving the neurocognitive and behavioural outcomes among formula-fed infants…
- Trial name
- NCT05310396
- Testing
- Experimental formula, Control Formula
- Where
- Philippines
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Mental Health Issue
Web-Based Cognitive Behavior Therapy for Procrastination
The main purpose of this study is to present the development process and project flow of an internet-based self-help intervention programme to reduce the level of procrastination among university students.
- Trial name
- NCT06278142
- Testing
- Internet Based Intervention - GUIDED, Internet Based Intervention - WİTHOUT GUİDANCE
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Anadolu University
Healthy, Infant
Infant s Examination and Manipulation of Objects
This study will explore how babies become able to use their experience with objects to plan to manipulate them appropriately. For example, an adult knows that picking up a grocery bag full of canned food requires different…
- Trial name
- NCT00053469
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
General Anesthetics Toxicity, Postoperative Cognitive Dysfunction
Tau/P-Tau and Neurocognitive Outcomes in Children
The proposed studies are aimed to measure Tau and P-Tau levels in pre- and postoperative blood, urine, feces and saliva, as well as to assess pre- and postoperative neurocognitive function in children (3 to 5 years old) who will…
- Conditions
- General Anesthetics Toxicity, Postoperative Cognitive Dysfunction, Child Development
- Trial name
- NCT03511729
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Major Depressive Disorder
Therapist-Guided Smartphone-Delivered CBT for MDD
We are testing a smartphone app that provides therapy for depression. Participants will also receive short weekly virtual appointments with a therapist.
- Trial name
- NCT05386329
- Testing
- Mindset: Therapist-guided smartphone-delivered CBT
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Massachusetts General Hospital
ADHD
Metacognitive Intervention in Children and Adolescents With ADHD - MiA Study
The aim of the MiA-Study is to address the current lack of effective treatment options to reduce cognitive and physical long-term problems in children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- MiA (NCT07162831)
- Testing
- Mio-Training
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Multimorbidity, Hypertension
Development and Validation of a Comprehensive Management Service Package for Older Adults With Multimorbidity
This study aims to test a new comprehensive management service package for older adults with two or more chronic conditions (multimorbidity).
- Conditions
- Multimorbidity, Hypertension, Diabetes Mellitus, Coronary Artery Disease
- Trial name
- COMPASS (NCT07151430)
- Testing
- Service Package Group
- Volunteers
- 358 people
- Sponsor
- Xuanwu Hospital, Beijing
Fatigue
Measure of Fatigue in Functional MRI
The purpose of this study is to determine more objective, central and peripheral indices of fatigue state by exploring the neural and behavioral correlates of the alert process while keeping the idea to corroborate these results…
- Trial name
- FATIGUE (NCT02379013)
- Testing
- Volunteer with MRI
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hôpital NOVO
Autism Spectrum Disorder (ASD)
Omega-3 Fatty Acids Monotherapy in Children and Adolescents With Autism Spectrum Disorders
The primary aim of this study is to examine the efficacy and tolerability of short-term omega-3 fatty acids monotherapy in youth with Autism Spectrum Disorders (ASD).
- Trial name
- NCT01248130
- Testing
- Omega-3 Fatty Acid
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
A Deep Learning Algorithm Platform to Predict Autism Diagnosis and Subtypes
This is the first human study on ASD microbiome with robust methodologies: prospective and sibling designs, metagenomics profiles, establishing an ASD multi-dimensional databank (clinic, behavior, neurocognition, brain imaging…
- Trial name
- NCT04873674
- Testing
- ASD diagnosis, Psychiatric diagnosis
- Where
- Taiwan
- Volunteers
- 420 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder (ASD)
Acceptance and Commitment Therapy for Parents of Children With ASD: Effects on Cognitive Fusion, Stigma, and Mindfulness
The goal of this intervention is to evaluate whether Acceptance and Commitment Therapy (ACT) can improve psychological well-being among parents of children with Autism Spectrum Disorder (ASD) in Saudi Arabia.
- Trial name
- ACT-CFSM (NCT07582627)
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- University of Jazan