Clinical trials: Cognitive Deterioration
Cognitive Impairment, Cognitive Decline
Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA)
This observational cohort study in healthy volunteers establishes normative data for the German version of the Montreal Cognitive Assessment (MoCA) and investigates the possible impacts of demographics on the MoCA total score.
- Conditions
- Cognitive Impairment, Cognitive Decline, Cognition Disorders, Cognitive Symptom
- Trial name
- MoCA-Norm (NCT03246269)
- Testing
- MoCA
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Andreas Monsch
Cognitive Impairment, Cognitive Decline
Personalized Virtual Reality Naturalistic Scenarios in Cognitive Impairment
The goal of this feasibility study is to investigate the feasibility of a personalized naturalistic Virtual Reality scenario by assessing motion-sickness effects, engagement, pleasantness, and emotions felt considering a sample…
- Conditions
- Cognitive Impairment, Cognitive Decline, Cognitive Deterioration, Anxiety State
- Trial name
- NCT05863065
- Testing
- Exposure to a Virtual Reality scenarios
- Where
- 2 sites in Italy
- Volunteers
- 23 people
- Sponsor
- University of Padova
Cognitive Deterioration
Objective Measurement of Pain in Individuals With Cognitive Deterioration Utilizing Electroencephalography
This research addresses the challenge of pain assessment in individuals with cognitive deterioration (CD), a common aspect of aging and various neurological conditions.
- Trial name
- NCT06256666
- Testing
- BIS Quantitative EEG
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Azienda USL Toscana Nord Ovest
Cognitive Deterioration
Safe & Easy for Alzheimer's Disease and Related Pathologies
All over the world the increasing prevalence of chronic disorders and its impact on functional decline is challenging the sustainability of health care systems.
- Trial name
- SaFEE2 (NCT02518243)
- Testing
- Patient's answer with non pharmacological therapeutic
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Multiple Sclerosis
GTA-MEG as a Biomarker for Cognition in MS
In this study, 100 persons with Multiple Sclerosis and 50 matched controls will be examined with magnetoencephalography (MEG), magnetic resonance imaging (MRI) and cognitive tests.
- Trial name
- NCT02851342
- Where
- Belgium
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Clinical Deterioration
Prevention of Functional and Cognitive Impairment Through a Multicomponent Exercise Program in Hospitalized Older Adults
The goal of this clinical trial is to determine whether a multicomponent exercise program improves functional capacity and cognitive status in hospitalized elderly patients aged 75 and older.
- Trial name
- PREDISC (NCT06634147)
- Testing
- Exercise
- Where
- 2 sites in Spain
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Fundacion Miguel Servet
Cognitive Decline, Cognitive Impairment
Preoperative Cognitive Training for Postoperative Cognitive Dysfunction
Postoperative Cognitive Dysfunction (POCD) is a state of decline in cognitive ability after surgery and is frequently seen among our elderly population.
- Conditions
- Cognitive Decline, Cognitive Impairment, Cognitive Deterioration
- Trial name
- CogniTrain (NCT03353987)
- Testing
- Cognitive training
- Where
- Malaysia
- Volunteers
- 17 people
- Sponsor
- University of Malaya
Branch Atheromatous Disease, Cognitive
Cognitive Outcomes in BAD-related Stroke
Branch atheromatous disease (BAD) is a distinct subtype of ischemic stroke that is particularly prevalent among Chinese and other Asian populations.
- Conditions
- Branch Atheromatous Disease, Cognitive, Deterioration, Clinical
- Trial name
- NCT07761182
- Testing
- END exposure
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Cognitive Deterioration
Safe & Easy Environment at Home for Patients Presenting a Frail Syndrome
All over the world the increasing prevalence of chronic disorders and its impact on functional decline is challenging the sustainability of health care systems.
- Trial name
- SafEE (NCT02288221)
- Testing
- Patient's answer with non pharmacological therapeutic, Patient's answer without non pharmacological therapeutic
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cognitive Deterioration
Effects of Petroleum Compounds on Psychological Health and Cognitive Functions
Over the last decade, awareness of the effects of hydrocarbon fuels on neurodegenerative disorders has increased significantly, as they are ubiquitous environmentally toxic chemicals that affect the central nervous system and…
- Trial name
- NCT06380998
- Testing
- whey protien
- Where
- Egypt
- Volunteers
- 196 people
- Sponsor
- Assiut University
SARS-CoV-2 Infection, Cognitive Change
The ACDC Study Assessing Cognitive Deterioration in COVID-19
The long-term impact and effects of COVID-19 are still being determined. However, what is clear, is that some people are still struggling following a period of illness with COVID-19.
- Conditions
- SARS-CoV-2 Infection, Cognitive Change, Cognitive Dysfunction
- Trial name
- ACDC (NCT05855434)
- Testing
- Magnetic Resonance Imaging
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- NHS Grampian
Hypobaric Hypoxia, Cognitive Deterioration
Effects of Acute Hypobaric Hypoxia Exposure on Neurocognitive Performance of Pre-hospital Emergency Service Providers
The study aims to evaluate the effects of acute hypobaric hypoxia on cognitive performance (H0: cognitive performance at 200 meters above sea level (asl) = cognitive performance at 3000 meters above sea level = cognitive…
- Conditions
- Hypobaric Hypoxia, Cognitive Deterioration, Emergency Medicine, Resuscitation
- Trial name
- NCT04138446
- Testing
- Altitude exposure in climate chamber
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine