Clinical trials: Cognitive Control
Provoked Vestibulodynia, Vulvodynia, Generalized
Internet-based Treatment for Provoked Vestibulodynia
Provoked vestibulodynia is a pain condition, which is associated with lower quality of life and discomfort. Furthermore, it is underdiagnosed and undertreated.
- Trial name
- NCT04045041
- Testing
- Acceptance and commitment therapy
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Uppsala University
Cardiac Disease, Cognitive Dysfunction
Cerebral Oxygen Saturation Monitoring In Cardiac Surgery (COSMICS)
Neurological dysfunction continues to be one of the complications of considerable concern in patients undergoing cardiac surgery.
- Trial name
- COSMICS (NCT04766554)
- Testing
- Cerebral oximetry monitor (The INVOS® Cerebral/Somatic Oximeter) and protocol-based interventions
- Where
- 2 sites in Brazil
- Volunteers
- 326 people
- Sponsor
- Instituto Nacional de Cardiologia de Laranjeiras
Stress Relief
Stress Relief Effect of Korean Red Ginseng
The purpose of this study is to examine clinical and neuropsychiatric effects of Korean Red Ginseng and examine changes in brain structure, function and metabolites.
- Trial name
- NCT01542905
- Testing
- Korean Red Ginseng
- Where
- South Korea
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Dementia
Study on the Efficacy of Speed-Feedback Therapy for Elderly People With Dementia
The purpose of this study is to verify the efficacy of speed-feedback therapy in improving the cognitive function of elderly people with dementia by a randomized controlled trial, and to demonstrate how that affects ADL and QOL.
- Trial name
- NCT00450047
- Testing
- Speed-feedback therapy system with a bicycle ergometer, Ergometer at conventional settings
- Volunteers
- 120 people
- Sponsor
- Hiroshima University
Major Depressive Disorder
Rise Study for Depression
This study will examine the efficacy of digital CBT versus waitlist in improving symptoms for adults with Major Depressive Disorder.
- Trial name
- NCT06003361
- Testing
- Digital CBT, Waitlist
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Big Health Inc.
Subjective Cognitive Decline
tDCS-enhanced Working Memory Training in Subjective Cognitive Decline
This 2-armed randomized, sham-controlled, single-blind study aims at providing evidence for the efficacy of a transcranial direct current stimulation (tDCS)-enhanced cognitive control training (PASAT) in participants with…
- Trial name
- NCT03236454
- Testing
- DC-Stimulator MC, NeuroConn
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Fibromyalgia
A Study To Assess Esreboxetine's Effect On Concentration, Memory, Decision Making And Problem Solving In Patients With Fibromyalgia.
The study is designed to assess if esreboxetine can improve the cognitive function of patients with fibromyalgia. Cognitive function is defined as the ability to concentrate, remember things and make decisions or problem solve.
- Trial name
- NCT00752505
- Testing
- Esreboxetine
- Where
- 7 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Pfizer
Major Depressive Disorder
Efficacy and Cost-effectiveness of Internet-delivered CBT for Adolescents With Depression
Adolescent depression is a prevalent and impairing condition that can be effectively treated with Cognitive Behavior Therapy (CBT). However, a majority of adolescents do not have access to CBT.
- Trial name
- IDA (NCT04977856)
- Testing
- Behavioral activation (BA), Regular care within primary or secondary mental health care for children
- Where
- Sweden
- Volunteers
- 219 people
- Sponsor
- Region Stockholm
Autism Spectrum Disorder, Asperger Syndrome
Effects of a Multimodal Exercise Program for Children With ASD
Exploring the effects of an exercise program for children ages 6 -26 years old who have been diagnosed with autism spectrum disorder and neurotypical children respond to high-intensity whole body exercise interventions (Group 1)…
- Trial name
- NCT05509231
- Testing
- High-intensity exercise, Wearable glove and arm sleeve device to measure movement
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Anxiety Disorders
Effects of tDCS on Fear Reversal in Patients With Anxiety Disorders
This study evaluates the effects of single-session Transcranial Direct Current Stimulation (tDCS) on fear reversal learning in patients with anxiety disorders.
- Trial name
- NCT07405463
- Testing
- Cathodal tDCS (rDLPFC), Anodal tDCS (vmPFC), Anodal tDCS (lDLPFC)
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Jingchu Hu
Menopause, Menopausal Vasomotor Symptoms
Internet-Delivered CBT Program for Menopausal Vasomotor Symptoms
Given the impact that hot flashes and night sweats can have on daily life during the menopausal transition, our team has developed a therapist-guided online cognitive behavioural therapy (CBT)- based program to help individuals…
- Trial name
- ICBT-Meno-VS (NCT07873177)
- Testing
- Internet-delivered Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Complex Post-Traumatic Stress Disorder
Patient-centered Modular CBT for CPTSD: A Randomised Controlled Pilot Study
Modular Patient Centred CBT (MPC) for Complex PTSD (CPTSD) is a manualized psychotherapy programme that consists of five treatment modules addressing 1) Affect dysregulation, 2) Disturbed relationships, 3) Negative self-concept…
- Trial name
- PACE pilot RCT (NCT05259592)
- Testing
- Psychotherapy
- Where
- 5 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Danish Veterans Centre
Brain Injuries, Growth Hormone Deficiency
Treatment Of Adult Growth Hormone Deficiency After Traumatic Brain Injury
To establish the effects of genotropin replacement on cognitive function in patients with severe growth hormone deficiency after traumatic brain injury.
- Trial name
- NCT00555009
- Testing
- Genotropin
- Where
- 9 sites in France, Italy and 4 more
- Volunteers
- 10 people
- Sponsor
- Pfizer
Cognitive Impairment, Alzheimer Disease
A Pharmacodynamics, Safety, and Pharmacokinetics Study of THN201 Versus Donepezil in Healthy Male Volunteers
This study explores the safety, pharmacodynamics and pharmacokinetics of THN201 a combination of donepezil and mefloquine to improve cognitive function in healthy male volunteers after impairment by a scopolamine challenge.
- Trial name
- NCT03698695
- Testing
- THN 201, Donepezil
- Where
- 7 sites in France
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Theranexus
Mild Cognitive Impairment
Cognitive Activation Therapy for MCI: A Randomized Control Study
Mild cognitive impairment (MCI) describes an initial phase of cognitive decline, usually among older adults, in which a person notices a decline in attention or memory, and performs worse than normal on cognitive tests of such.
- Trial name
- FarbMCI2012 (NCT01641328)
- Testing
- Cogntive Activation Training, Waitlist Control / Home-based training
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Rotman Research Institute at Baycrest
Cognitive Impairment Associated With Schizophrenia (CIAS)
A Study To Evaluate The Safety And Efficacy Of PF-04958242 In Subjects With Cognitive Impairment Associated With Schizophrenia (CIAS)
The purpose of this study is to determine whether PF-04958242 is safe and effective in the treatment of cognitive dysfunction in schizophrenia subjects
- Trial name
- NCT02855411
- Testing
- PF-04958242
- Where
- 16 sites in United States
- Volunteers
- 35 people
- Sponsor
- Biogen
Obsessive-Compulsive Disorder (OCD)
Feasibility of Modulating Cognitive Control in OCD
This study tests out procedures to look at whether a type of brain stimulation called transcranial magnetic stimulation impacts flexible shifts in behavior in obsessive-compulsive disorder (OCD).
- Trial name
- NCT07419009
- Testing
- continuous theta-burst transcranial magnetic stimulation (cTBS)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Social Anxiety Disorder, Separation Anxiety Disorder
Stepped Versus Stratified Care for Anxiety Disorders in Youth
The goal of this clinical trial is to compare stepped care to stratified care as overall healthcare models for children and adolescents aged 8-17 with anxiety disorders.
- Conditions
- Social Anxiety Disorder, Separation Anxiety Disorder, Specific Phobia, Panic Disorder
- Trial name
- NCT06942429
- Testing
- Internet-delivered cognitive-behavioral therapy, Personalized in-person cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 556 people
- Sponsor
- Region Skane
Type 2 Diabetes Mellitus, Cognitive Impairment
Efficacy and Safety of Canagliflozin in the Treatment of Type 2 Diabetes With Mild Cognitive Impairment
The prevalence of cognitive dysfunction in diabetic patients is high, which seriously affects the quality of life of patients, and early intervention is of great significance.
- Trial name
- NCT07711171
- Testing
- Canagliflozin group, Sitagliptin, Acarbose
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Fudan University
Insomnia, Schizophrenia
Cognitive Behavioral Therapy for Insomnia (CBT-I) in Schizophrenia(SLEEPINS)
Sleep problems are pervasive in people with schizophrenia. In our study, our goal is to determine whether we can alleviate sleep symptoms and improve quality of life and well-being in patients with major psychiatric disorders…
- Conditions
- Insomnia, Schizophrenia, Schizoaffective Disorder
- Trial name
- SLEEPINS (NCT04144231)
- Testing
- iCBT-I, GCBT-I
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Helsinki University Central Hospital