Clinical trials: Cognitive Control
Cognitive Assessment, Working Memory
Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.
The proposed project will evaluate the synergistic effects of a nutritional formulation, 'Think Tank' on cognitive performance following exposure to a psychological and physical stressor.
- Conditions
- Cognitive Assessment, Working Memory, Executive Function (Cognition), Sustained Attention
- Trial name
- NCT07319117
- Testing
- Skoshify 'Think Tank' Formulation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Cognitive Training, Functional Core Stability Training
Effect of Functional Core Stability Training or Cognitive Training on Balance and Postural Control in Chronic Ankle Instability
The purpose of the study is to investigate dynamic core stability training versus cognitive training on balance, functional performance, postural control, ankle instability scores, ankle dorsiflexion range of motion, and mental…
- Conditions
- Cognitive Training, Functional Core Stability Training, Balance; Distorted, Postural Control
- Trial name
- NCT07283276
- Testing
- strengthening exercises, Balance training, Functional core training
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Mild Cognitive Impairment, Alzheimer Disease
Development of an EEG Diagnostic for Alzheimer's Disease
The purpose of this research is to collect and compare electroencephalogram data from all stages of Alzheimer's disease from preclinical through severe dementia.
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Dementia With Lewy Bodies, Normal Control APOE e4 Carriers and Noncarriers
- Trial name
- NCT04954183
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Mayo Clinic
Emotion Regulation, Cognitive Control
The Effects of Exercise on Emotion Regulation and Cognitive Control in PTSD
The goal of this study is to investigate the effects of a single bout of aerobic exercise on neurophysiological indices of emotion regulation and cognitive control in individuals with clinically significant PTSD symptoms.
- Conditions
- Emotion Regulation, Cognitive Control, PTSD
- Trial name
- NCT05643716
- Testing
- Aerobic Exercise
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Anxiety, Depression
Electroencephalographic Study of the Mechanisms of Inhibition of Emotional Memories in Young Healthy Subjects
Forgetfulness has long been considered a pathology of memory. However, the brain's voluntary suppression of certain unpleasant memories is essential for building a healthy memory.
- Conditions
- Anxiety, Depression, Cognitive Control
- Trial name
- ENGRAMME (NCT06891612)
- Testing
- Cognitive Assessments, Eye-tracking, Electroencephalography (EEG)
- Where
- France
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Alzheimer Disease, Mild Cognitive Impairment
Novel Diagnostic and Disease Stage Biomarkers in AD
This study will investigate the efficacy of novel biomarkers, namely blood-based biomarkers, pupillometry and actigraphy to track and predict progression of Alzheimer's disease (AD).
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Neuro-Degenerative Diseases, Vascular Dementia
- Trial name
- TRACK-AD (NCT05175664)
- Testing
- Long-term study, Short-term study, Cross-sectional study
- Where
- Denmark
- Volunteers
- 350 people
- Sponsor
- Danish Dementia Research Centre
Diabetic Kidney Disease, Cognitive Function
Metabolism of Low Carbohydrate and Ketogenic Diet
This study will assess the preliminary efficacy of a lifestyle intervention including low-carb/ketogenic diet and exercise, enhanced by self-monitoring through health technologies on weight and diabetes outcomes (Glucose, HbA1c)…
- Conditions
- Diabetic Kidney Disease, Cognitive Function, Weight Loss, Diabetic Control
- Trial name
- NCT05071287
- Testing
- mHealth + low-fat diet, mHealth + low-carb/ketogenic diet
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Brain Insulin Sensitivity, Brain Vascular Function
Effects of Ketone Monoesters on Brain Function
Disturbances in brain insulin-sensitivity are not only observed in obesity and type 2 diabetes (T2D), but also during brain aging and in dementia.
- Conditions
- Brain Insulin Sensitivity, Brain Vascular Function, Cerebral Blood Flow, Cognitive Performance
- Trial name
- NCT06395051
- Testing
- Ketone Monoester
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cognitive Impairment, Healthy Control
Prediction of MMSE Scores for Cognitive Impairment
This study aims to explore the potential of using machine learning (ML) algorithms to predict cognitive status, specifically MMSE scores, based on oral health and demographic data.
- Trial name
- NCT06611475
- Testing
- MMSE ≤26
- Where
- Sweden
- Volunteers
- 693 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Inattention, Cognitive Training
RECOGNeyes Gaze-Control Training
RECOGNeyes is a computer game developed by members of the research team to improve attention in people who find it hard to "keep their eyes on the task".
- Conditions
- Inattention, Cognitive Training, Cognitive Control, Oculomotor Dysfunction
- Trial name
- NCT06691646
- Testing
- Gaze-control training game
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Cognitive Fatigue, Mental Fatigue
Cognitive Fatigue, Self-Regulation, and Academic Performance: A Physiological Study
This study aims to examine the relationship among cognitive fatigue, self-regulation, and academic performance.
- Conditions
- Cognitive Fatigue, Mental Fatigue, Behavioral Performance, Heart Rate Variability
- Trial name
- FRAPS (NCT05012293)
- Testing
- Baseline, Fatigue Manipulation
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Cognitive Impairment, Child Autism
Exercise and Cognition in Children With ASD
Physical exercise is widely reported to be beneficial to executive functions (EFs) in children with autism spectrum disorder (ASD).
- Trial name
- NCT05503459
- Testing
- Bicycle learning, Stationary cycling
- Where
- Hong Kong
- Volunteers
- 82 people
- Sponsor
- Education University of Hong Kong
Poor Glycemic Control, Cardiovascular Risk Factors
The Potential of Carnosine Supplementation in Optimising Cardiometabolic Health
The investigators hypothesise that carnosine supplementation will improve: 1. glycaemic control 2. cardiovascular risk factors 3.
- Conditions
- Poor Glycemic Control, Cardiovascular Risk Factors, Cognitive Function 1, Social
- Trial name
- NCT02917928
- Testing
- carnosine
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Monash University
Treatment, Active Control
Cognitive Training Delivered Remotely to Individuals With Psychosis (ROAM)
Primary study: This study is a single-site, double-blind, randomized, controlled clinical trial to compare an evidence-based structured program of 30-35 hours of on-line cognitive and social cognitive training exercises performed…
- Conditions
- Treatment, Active Control, Schizophrenia, Psychosis
- Trial name
- NCT02782442
- Testing
- Structured Cognitive Training & PRIME, Computer Games Control & PRIME
- Where
- 2 sites in United States
- Volunteers
- 109 people
- Sponsor
- University of Minnesota
Well-being, Emotion Regulation
Cognition and Emotion in Meditation: A Comparison Between Mindfulness and Compassion Standardized Programs
The study is aimed at comparing the differential effects of two widely used standardized meditation programs: Mindfulness-Based Stress Reduction (MBSR) and Compassion Cultivation Training (CCT) in general population samples.
- Conditions
- Well-being, Emotion Regulation, Cognitive Control, Attention
- Trial name
- NCT03920241
- Testing
- Mindfulness-Based Stress Reduction, Compassion Cultivation Training, Control Group
- Where
- Spain
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Mild Cognitive Impairment, Alzheimer Disease
Cerebral Haemodynamic Changes During Cognitive Testing: A fTCD Study
850,000 people live with dementia in the UK, with that number expected to rise to more than 1 million within the next 5 years. The most common type of dementia (55%) is Alzheimer's dementia, and vascular dementia is the second…
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Vascular Dementia, Healthy Controls
- Trial name
- NCT03134963
- Testing
- Transcranial doppler ultrasonography, Blood pressure monitoring, Heart rate monitoring
- Where
- 2 sites in United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Mild Cognitive Impairment, Healthy Controls
Cross-Cultural Use of Performance-Based Functional Assessment in Alzheimer's Disease
This study plans to assess the effectiveness of performance-based functional assessments (PBFAs) and cognitive assessments in diagnosing Alzheimer's disease in Hispanic/Latino populations.
- Trial name
- NCT03081546
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cognitive Therapy, Control
Efficacy of Cognitive Behavioral Therapy and Hair Cortisol Concentration
Stress is considered as a risk factor for physical and mental health. For this reason, interventional programs focused on stress management have been developed.
- Trial name
- NCT03476200
- Testing
- Cognitive Behavioral Therapy
- Where
- Spain
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Cognitive Control
Measuring Plasticity in SFC/dACC Following Theta-Burst-Stimulation Using TMS
This is a study to determine whether particular forms of brain-stimulation, applied to superior frontal cortex/preSMA can affect cognition and associated frontal theta oscillations.
- Trial name
- BTMS (NCT03946059)
- Testing
- iTBS then cTBS, cTBS then iTBS
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Cognitive Control, Executive Function
Effect of Cross Frequency tACS on Cognitive Control
Investigation of frequency specific transcranial alternating current stimulation on cognitive control signals in frontal cortex
- Trial name
- NCT03800030
- Testing
- Theta-gamma tACS, Delta-beta tACS
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill