Clinical trials: Cognitive Changes
Menopause, Cognitive Dysfunction
Brain Fog and Life Quality in Menopause
This clinical study aims to investigate cognitive changes in women undergoing the menopausal transition, with a specific focus on the prevalence, characteristics, and impact of brain fog.
- Conditions
- Menopause, Cognitive Dysfunction, Memory Disorders, Quality of Life
- Trial name
- NCT06978218
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Merve Coskun
Delirium
Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients
The purpose of this chart review study is to determine whether the use of dexmedetomidine, a selective α2-adrenergic receptor agonist with sedative, analgesic, and antinociceptive properties, would be associated with a lower…
- Trial name
- NCT00417664
- Testing
- Dexmedetomidine, Propofol, Midazolam
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cognitive Change
Assessing the Effects of the Muse Meditation System on Cognition and Well-being
Interaxon markets a head-worn EEG biofeedback device ('Muse') to encourage and aid effective meditation and sleep. This device has been previously shown to improve workplace wellness, fatigue and quality of life, and performance…
- Trial name
- MuseCog (NCT04790929)
- Testing
- Muse, Meditation Coaching
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Attention Impaired, Mental Health Issue
Brief Mental Training and Internal Attentional Control
Previous research documented that real-time feedback on attention as well as related forms of mental training (e.g. mindfulness meditation) may be used to train and impact external attentional control.
- Conditions
- Attention Impaired, Mental Health Issue, Rumination
- Trial name
- NCT05353231
- Testing
- Attention Feedback Awareness and Control Training (A-FACT), Mindful Disengagement from Thoughts Training (MDTT)
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Neurocognitive Model, Decision-Making
Motivation, Learning and Decision Making in Changing Environments
The main objective of this study is to develop a models of sequential decision-making, learning and motivation that includes emotions as driving forces of adaptive behaviour.
- Trial name
- MOTILEARN (NCT07314112)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Cognitive Change
Understanding Individual Differences in Working Memory Training and Transfer in Older Adults
The present study investigates how individual differences in cognitive processing contribute to the efficacy of working memory training programs in an older adult population.
- Trial name
- NCT05396586
- Testing
- N-back, Span, Multisensory
- Where
- 2 sites in United States
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Cognitive Change, Cognitive Impairment
The Everyday Function Intervention Trial
Loss of independence, cognitive decline, and difficulties in everyday function are areas of great concern for older adults and their families.
- Conditions
- Cognitive Change, Cognitive Impairment, Healthy Aging, Dementia
- Trial name
- EFIT (NCT04651582)
- Testing
- Cognitive Training, Cognitive Stimulating Activities
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Clemson University
Sleep Deprivation
A Change in Diet May Decrease the Negative Consequences of Chronic Sleep Deprivation
The purpose of this study is to determine whether or not a low calorie, low glycemic index diet with omega-3 fatty acid supplements can prevent some of the negative consequences of sleep deprivation.
- Trial name
- NCT00123214
- Testing
- Controlled Dietary Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- St. Vincent's Medical Center
Depression
iCBT and ABM for Reducing Depressive Symptoms in Firefighters
The study aimed to examine the impact of a combined internet-delivered Cognitive Behavioral Therapy (iCBT) and Attention Bias Modification (ABM) intervention to reduce depressive symptoms in firefighters.
- Trial name
- NCT05741684
- Testing
- Internet-delivered Cognitive Behavioral Therapy, Attention Bias Modification
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Cognitive Change
Effectiveness of Cognitive Training in Older and Younger Adults
The proposed study will enroll 1600 participants to examine the effectiveness of cognitive training. Participants will be randomized into different experimental groups and can expect to participate for up to 15 hours of research…
- Trial name
- NCT06375681
- Testing
- Visual and / or Auditory Cognitive Tasks (1), Visual and / or Auditory Cognitive Tasks (2)
- Where
- 3 sites in United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Parkinson Disease
Evidence of Neuroplasticity After Performing a Cognitive Task in Idiopathic Parkinson's Disease Patients
As seen in previous studies Diffusion Tensor Imaging (DTI) MRI is able to detect very subtle changes in brain tissue even after a very short timescale of hours resulting from performing a cognitive task and learning, We wish to…
- Trial name
- NCT02494908
- Testing
- Playing a computer game simulating a car race
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dr. Sharon Hassin
Mild Cognitive Impairment, Cognitive Dysfunction
Effects of a Computerized Cognitive Stimulation Intervention Adapted to the Level of Cognitive Reserve
Normal ageing presents subtle cognitive changes that can be detected before meeting the criteria for Mild cognitive impairment (MCI).
- Trial name
- NCT06279325
- Testing
- Computerized cognitive stimulation program, Face-to-face training-explanatory session
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Obesity, Morbid
Suboptimal Weight Loss After Gastric Bypass Surgery
Bariatric surgery is the only long-term established treatment for morbid obesity. However, some patients experience suboptimal weight loss after surgery and/or experience a significant weight regain.
- Trial name
- NCT01829906
- Testing
- Multidisciplinary outpatient programme, Inpatient lifestyle programme
- Where
- Norway
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Alteration of Cognitive Function, Ageing
Health Behaviors and Time-of-Day: Older Adult Cognitive Function
This is a single-center, observational study design. Enrolled participants will be typically, healthy older adults. Participants will complete daily computerized measures, in addition to continuously wearing an Actiwatch device.
- Trial name
- OA-TIME (NCT02300272)
- Testing
- Polysomnograph, Actiwatch
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy
A Healthy Volunteer Trial to Gain Information About the Blood Concentrations of PF-06412562 After Oral Administration of a Modified Release Formulation in Fasted and Fed Conditions
The study is designed to understand the blood concetration of PF-06412562 and its metabolite, PF-06663872, following a single oral dose of a modified release formulation.
- Trial name
- NCT02201511
- Testing
- 3 mg PF-06412562 MR tablets_Fasted, 2 x 15 mg PF-06412562 MR tablets_Fasted, 2 x 15 mg PF-06412562 MR tablets_Fed
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Trauma, Stress, Emotional
Cognitive Appraisals and Team Performance Under Stress in Simulated Trauma Care
Medical teams work in demanding situations that are often uncertain, changeable and require accurate decision-making, skilled movement and coordinated action. How teams perform matters for patient outcomes.
- Conditions
- Trauma, Stress, Emotional, Cognitive Change
- Trial name
- NCT05083871
- Testing
- European Trauma Course
- Where
- Italy
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Azienda Usl di Bologna
Adolescent Behavior, Dental Plaque
Evaluating the Effectiveness of a Cognitive Behavioral Intervention (CBI)
This is a Phase III, randomized, one-center, three arm parallel group, open label and single blind clinical study to evaluate the effectiveness of a cognitive behavioral intervention (CBI) adjunctive to a smart powered toothbrush…
- Conditions
- Adolescent Behavior, Dental Plaque, Gingivitis, Cognitive Change
- Trial name
- NCT05782348
- Testing
- Cognitive behavioral intervention, Colgate smart toothbrush
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Howard University
Aging, Cognitive Change
Investigating the Effects of Cocoa Flavanol on Cognition Assessed Online
The COcoa Supplement and Multivitamin Outcomes Study (COSMOS; NCT02422745) is a randomized clinical trial of cocoa extract supplement (containing a total of 500 mg/d flavanols, including 80 mg (-)-epicatechin), and/or a standard…
- Trial name
- COSMOS-Web (NCT04582617)
- Testing
- Cocoa Extract, Multivitamin
- Where
- 2 sites in United States
- Volunteers
- 3,959 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cognitive Impairment, Progressive, Cerebral Small Vessel Diseases
Circuit Training and Retina
The purpose of this research study is to see if high-speed weight training performed in a circuit (using one machine after another) can improve participant heart and brain function, strength, and power in older persons.
- Trial name
- NCT05714813
- Testing
- High-Speed Circuit Resistance Training, Lecture on Diet, Exercise and Cognition
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Miami
Spinal Cord Injuries, Neuropathic Pain
Identifying Body Awareness-related Brain Network Changes During Cognitive Multisensory Rehabilitation for Reduced Neuropathic Pain in People With Spinal Cord Injury
Many adults with spinal cord injury (SCI) suffer from long-term debilitating neuropathic pain. Available treatments, including opioids, are ineffective at eliminating this pain.
- Trial name
- NCT04706208
- Testing
- Cognitive Multisensory Therapy, Usual Care, Clinical Assessment
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Minnesota