Clinical trials: Cognitive Ability
Mental Health Issue, Development, Child
Development, Usability and Feasibility Pilot Study of a Videogame
Mental health disorders are one of the leading causes of illness globally. The importance of psychosocial skills acquired in early childhood, such as executive functions, inhibitory control, emotional regulation, and social…
- Conditions
- Mental Health Issue, Development, Child, Cognitive Ability, General
- Trial name
- Japi-1 (NCT07048119)
- Testing
- Japi 1.0
- Where
- Chile
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Memory Decline, Cognitive Decline
Anti-inflammatory Probiotics in Cognitive Functioning
The goal of this study is to explore the potential impact of an anti-inflammatory probiotic mixture of psychobiotics including Bifidobacterium longum Rosell®-175 and Lactobacillus helveticus Rosell®-52 on cognitive functions in…
- Conditions
- Memory Decline, Cognitive Decline, Cognitive Aging
- Trial name
- CoProM (NCT07165977)
- Where
- Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Dietary Intervention, Dietary Proteins
Investigating the Effects of Beef Consumption on Cognitive and Brain Health
The goal of this clinical trial is to learn if eating more beef will lead to better cognition and a healthier brain in younger adults.
- Conditions
- Dietary Intervention, Dietary Proteins, Dietary Assessment, Cognitive Ability, General
- Trial name
- NCT06690892
- Testing
- Ready-to-eat beef in frozen, 5-oz packages, Ready-to-eat beef in frozen, 1-oz packages
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Sleep Duration, Child Obesity
Effect of Sleep Extension on Body Weight and Learning in Children (More2Sleep)
More2Sleep is a randomized, controlled, parallel trial with two groups (sleep extension vs control) including 142 school-aged children (6-12 years) who have a BMI above average, defined as age- and sex-specific BMI Z-score above…
- Conditions
- Sleep Duration, Child Obesity, Child Development, Child Behavior
- Trial name
- More2Sleep (NCT06341179)
- Testing
- Sleep extension
- Where
- 3 sites in Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Tobacco Smoking in Schizophrenic Patients
Antismoking Effects of Electronic Cigarettes in Subjects With Schizophrenia and Their Potential Influence on Cognitive Functioning.
It is well established in studies across several countries that tobacco smoking is more prevalent among schizophrenic patients than the general population.
- Trial name
- SCARIS (NCT01979796)
- Testing
- Ecig 24 mg nicotine, Ecig 0 mg nicotine, Nicotine free inhalator
- Sponsor
- University of Catania
Memory
Galantamine Effects on Cognitive Function in Marijuana Users
To evaluate galantamine's effects on cognitive performance in marijuana users. Galantamine, an acetylcholine esterase inhibitor, is approved for treatment of Alzheimer's disease.
- Trial name
- NCT00969696
- Testing
- Galantamine
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yale University
Urolithiasis, Kidney Stone
Effects of Virtual Reality Education on Anxiety and Learning in Patients Undergoing Urolithiasis Surgery
This randomized controlled trial aims to evaluate the effects of two-tier virtual reality-based preoperative education on anxiety, learning knowledge, self-care ability, and cognitive load in patients undergoing urolithiasis…
- Conditions
- Urolithiasis, Kidney Stone, Ureter Stones
- Trial name
- VR-URO (NCT07620873)
- Testing
- VR Education, Two-Tier VR Education
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Wei-Lin, Huang
Depression
The Effect of Duloxetine on Mood, Quality of Life and Cognitive Functioning in Glioblastoma Patients
Primary tumor glioblastoma is the most common malignant brain. Standard treatment includes biopsy or excision of the tumor in order to obtain a pathological diagnosis, and tumor mass reduction.
- Trial name
- NCT02443194
- Testing
- duloxetine
- Volunteers
- 50 people
- Sponsor
- michal roll
Opioid Use Disorder, Cognitive Ability General
Older Adults, Methadone, and Cognitive Function
The increasing prevalence of opioid use disorder (OUD) among older adults, coupled with high overdose rates and cognitive impairments associated with opioid use, highlights a critical gap in addiction treatment.
- Trial name
- NCT07153029
- Testing
- Smartphone based cognitive tasks
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Maryland, Baltimore
Affective Disorder
Effectiveness of a Cognitive Remediation Intervention Based on Virtual Reality for Promotion of Cognitive Functioning and Participation in Daily Life Among Persons With Affective Disorder
The purpose of this study is to test the efficacy of remedial cognitive intervention using The Functional Brain Trainer VR (FBT, Intendo ©) to improve cognitive functioning, participation in daily life occupations, and functional…
- Trial name
- NCT04288609
- Testing
- Intendu, Paper and Pencil cognitive remediation training
- Volunteers
- 40 people
- Sponsor
- Geha Mental Health Center
Math Learning Disability, Learning Disabilities
Intervention on Mathematical Problem-Solving Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing and remediating weaknesses in arithmetic skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Learning Disabilities, Learning Disabilities, Child, Dyscalculia
- Trial name
- NCT07778706
- Testing
- Speeded practice training, Arithmetic strategy training
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Stanford University
Alzheimer Disease, Preclinical Alzheimer's Disease
Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping - FUTURE Extension
The primary objective of the study is to evaluate whether a set of algorithms analysing acoustic and linguistic patterns of speech, can predict change in Preclinical Alzheimer's Clinical Composite with semantic processing (PACC5)…
- Conditions
- Alzheimer Disease, Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Alzheimer's Disease (Incl Subtypes)
- Trial name
- FUTURE-US (NCT04951284)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Novoic Limited
Cognitive Ability General, Functional Abilities
Automated IADL Sensing to Refine Measurement of Older Adult Daily Activity
The instrumental activities of daily living (IADL) refer to complex daily activities required for adult independence, such as preparing a meal or taking medications.
- Trial name
- NCT07585864
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cognitive Changes Due to Organic Disorder (Finding), Dementia
Gerontology Research Programme: The Singapore Longitudinal Ageing Studies (SLAS I & II)
The Gerontology Research Programme (GRP) in the National University Singapore's Department of Psychological Medicine, was formed to coordinate and facilitate the conduct of multi-disciplinary research on in a wide range of…
- Conditions
- Cognitive Changes Due to Organic Disorder (Finding), Dementia, Mild Cognitive Impairment, Frailty
- Trial name
- SLAS (NCT03405675)
- Testing
- SLAS 1, SLAS 2
- Where
- Singapore
- Volunteers
- 6,183 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Schizophrenia
Neuroendocrine and Metabolite Substrates in Schizophrenia
Background: Schizophrenia is a serious mental illness. The diagnosis and severity evaluations of schizophrenia are generally based on patient behaviors.
- Trial name
- NCT02423096
- Testing
- Risperidone
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Empathy, Sleep
PAIN Empathy Assessment in Sleep Deprived Emergency & Acute Care Clinicians
Cognitive Empathy is relevant in clinical practice and will be assessed based on the accuracy of pain recognition and the pain intensity evaluation in a computerised task using facial expressions.
- Conditions
- Empathy, Sleep, Pain
- Trial name
- PAIN-EASE (NCT05235035)
- Testing
- Night shift work
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Claude Bernard University
Subacute Stroke
Study of Blood Flow Restriction and Cognitive-Motor Dual Task Training to Improve Strength, Gait, and Balance in People With Subacute Stroke
This study aims to evaluate the effects of individualized blood flow restriction (BFR) training combined with cognitive-motor dual task intervention on lower limb muscle strength, gait ability, and fall stability in patients with…
- Trial name
- NCT07138118
- Testing
- Blood Flow Restriction + Dual Task Training, Dual Task Training Only
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Sahmyook University
Sub-optimal Cognitive Function, Sub-optimal Immune Function
Evaluating Whole Foods Supplementation on Cognition
A six-month study which investigated the effect of Ginkgo Synergy® and Choline or OPC Synergy® and Catalyn® on cognitive and immune function markers and quality of life among healthy older adults with no history of significant…
- Trial name
- NCT01672359
- Testing
- Ginkgo Synergy® and Choline, OPC Synergy® and Catalyn
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Miami
Anxiety Disorders, Child Developmental Disorders, Pervasive
Examining Social, Emotional, and Cognitive Functioning in People With Fragile X and Down Syndromes
By testing physiological responses to anxiety in people with nervous system developmental disorders, this study will identify specific physiological characteristics associated with response to anxiety treatments.
- Trial name
- NCT00879515
- Where
- United States
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Aging, Physical Functioning
Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository
The purpose of this study is to use the MURDOCK Horizon 1.5 infrastructure (Duke Instutional Review Board Pro00011196) to specifically target and enroll 1,000 participants across age groups and other demographic categories in…
- Conditions
- Aging, Physical Functioning, Cognitive Functioning, Fitness
- Trial name
- PPS (NCT01720472)
- Testing
- Biomarker studies
- Where
- 6 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Duke University