Clinical trials: Cognition Function
Major Depressive Disorder
Repetitive Transcranial Magnetic Stimulation(rTMS) in the Treatment of Depression
The objective of this study is to investigate the antidepressant efficacy of rTMS, and to assess cortical metabolism before and after rTMS sessions in patients with major depression.
- Trial name
- NCT01198561
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Healthy
Investigating the Acute Effects of Blueberry (Poly)Phenols on Vascular Function and Cognition in Healthy Individuals.
This study aims to determine the effect of blueberry (poly)phenol vs placebo on vascular function and cognitive performance with an insight into cerebral blood flow velocity changes, across all ages of the general healthy…
- Trial name
- BluLife (NCT03592966)
- Testing
- Wild Blueberry Powder
- Where
- United Kingdom
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- King's College London
Mild Cognitive Impairment
The Effects of a Line Dance Program on Cognitive Function, Physical Function, and Quality of Life in Older Adults With Mild Cognitive Impairment
This study aims to evaluate the effects of a structured line dance program on cognitive function, physical performance, and quality of life in older women with mild cognitive impairment (MCI).
- Trial name
- LD-MCI (NCT07058844)
- Testing
- High-BPM Line Dance, Low-BPM Line Dance, Usual Daily Activity
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Wanyu Shu
Hypophosphatasia
The PORTRAIT Study
Clinical Consequences of Adults Presenting with Hypophosphatasia with Special Focus on Gait, Bone Microstructure and Cognition: The PORTRAIT study Hypophosphatasia (HPP) is an inherited condition that leads to weak bones.
- Trial name
- PORTRAIT (NCT04222452)
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Physical Function, Cognitive Decline
Face-to-face vs Online Physical Exercise in Seniors Living in Nursing Homes (ExerMOT-NH)
The benefits of multicomponent physical exercise (MPE) in the mental and physical health of older adults are widely accepted. However, during Covid19 pandemic, some face-to-face programs for physical exercise were canceled.
- Conditions
- Physical Function, Cognitive Decline, Psychological Well-Being
- Trial name
- ExerMOT-NH (NCT06352749)
- Testing
- Advice to increase physical activity and reduce sedentary behavior, Online Physical Exercise, Face-to-Face Exercise
- Where
- 4 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Driving
Accessing the Driving Skills After the Endoscopy of Intravenous Anesthesia by Driving Simulator
The purpose of this study is to assess the driving and cognitive ability of gastrointestinal endoscopy patients at different time points after intravenous anesthesia (propofol for example), and to explore whether the driving and…
- Trial name
- NCT02280148
- Testing
- Endoscopy of Intravenous Anesthesia, Driving Simulator, Propofol
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Heart Failure
Investigation of the Effect of Inspiratory Muscle Training and Dual-Task Inspiratory Muscle Training on Cognitive Functions in Heart Failure
The goal of this clinical trial is to evaluate whether dual-task inspiratory muscle training (IMT) is effective in improving cognitive and functional outcomes in adults with heart failure.
- Trial name
- NCT07581587
- Testing
- Dual-Task IMT, IMT
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University - Cerrahpasa
Parkinson Disease
Transcranial Direct Current Stimulation for Cognitive Improvement in Parkinson's Patients
The investigators hypothesize that multi-session anodal tDCS (atDCS) of the left dorsolateral prefrontal cortex (LDLPFC) will induce long-lasting effects in improving cognitive function and reducing cognitive fatigue and…
- Trial name
- tDCS (NCT03191916)
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Sanford Health
Listening Effort, Cognitive Function 1, Social
The Effect of Listening Effort, Cognition and Anxiety-depression in Listening Satisfaction by Hearing Aid Users
Brief Summary Introduction: Listening can be effortful in situations that require the intensive use of cognitive processing resources especially for individuals with a hearing loss.
- Conditions
- Listening Effort, Cognitive Function 1, Social, Anxiety, Depression
- Trial name
- NCT05781126
- Testing
- The Spatial Hearing Questionnaire, MINI-MENTAL STATE EXAMINATION, International Outcome Inventory - Hearing Aid, Glasgow Hearing Aid Benefit Profile, BECK-II and STAI questionnaires
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chania General Hospital "St. George"
Opiate Addiction
Examination of Cognitive Function in Patients Treated With Subutex
People who addicted to Heroin and other opiates suffer from a disease with approved genetic basis. It causes to a behavioral response as searching and using those drugs even though they know it causes severe damages as…
- Trial name
- NCT00687089
- Testing
- Sexual, cognitive functional tests and measurement weight
- Volunteers
- 60 people
- Sponsor
- BeerYaakov Mental Health Center
Benzodiazepine
Effect of Remimazolam Use During Perioperative Period on Brain Waves and Postoperative Cognitive Function
Benzodiazepine sedative hypnotics are commonly used intravenous anesthetics in clinical practice. Remimazolam is a new benzodiazepine with the characteristics of rapid onset, short maintenance and recovery time, no accumulation…
- Trial name
- NCT04601350
- Testing
- remimazolam group was induced with remimazolam 0.1 mg/kg followed by a maintenance dose of 0.1 mg·kg-1·h-1 for general anesthesia, control group was induced with midazolam 0.05 mg/kg followed by normal saline maintenance of 0.1 ml·kg-1·h-1
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yangzhou University
Safety, Peripheral Neuropathy
Xanamem™ in Healthy Elderly Subjects
Xanamem™ is being developed as a potential drug for Alzheimer's disease. This study drug has been designed to change the cortisol levels in the brain. Cortisol is a naturally occurring hormone in the body.
- Conditions
- Safety, Peripheral Neuropathy, Cortisol, Central Nervous System
- Trial name
- XanaHES (NCT03830762)
- Testing
- Xanamem
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Actinogen Medical
Iron-deficiency, Iron Deficiency Anemia
Fatigue, Quality of Life, Cognitive Function and Physical Ability in Patients Suspected of Colorectal Malignancy
The aim is to investigate if iron deficiency at the time of colorectal cancer diagnosis has an influence on fatigue, quality of life, cognition and physical ability.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Colorectal Cancer, Fatigue
- Trial name
- NCT04749589
- Testing
- iron deficiency
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Pain, Stiffness
Use of Whole-Body Periodic Acceleration Therapy To Aches and Pains
The purpose of this study is to test the effectiveness of whole body periodic acceleration for helping with symptoms of aches and pains suffered by many patients.
- Conditions
- Pain, Stiffness, Abnormal Gait, Balance
- Trial name
- Exer-Rest (NCT01629810)
- Testing
- Whole body periodic acceleration (Exer-Rest)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Center for Translational Medicine
Nutritional Supplementation
Nutrition21 Study 1
The purpose of this study is to determine the effects of nooLVL containing arginine and inositol supplementation on executive function and memory prior to and following playing video games.
- Trial name
- N21-1 (NCT04828278)
- Testing
- Arginine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Dementia, Aerobic Exercise
Investigation of the Effects of Aerobic Exercise, Balance Exercise and Combined Exercise Practices on Frailty, Balance, Fall Risk, Reaction Time, Cognitive Functions and Quality of Life in Dementia Patients
Dementia is a clinical disorder characterized by progressive and permanent loss of multiple cognitive functions, especially memory, at a level that affects activities of daily living.
- Conditions
- Dementia, Aerobic Exercise, Balance Exercise, Cognitive Function
- Trial name
- NCT05839743
- Testing
- Aerobic Exercise, Balance Exercise, Combined Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Yuksek Ihtisas University
Obesity
Enhancing Efficacy of Mango Polyphenols in Lean and Obese
The objective of this research is to determine beneficial impact of mango phytochemicals in lean and obese individuals for cognitive function and gut health.
- Trial name
- NCT04970589
- Testing
- Mango, Probiotics
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Young Adults
Effect Of Resistance Training On Physical Fitness, Cognitive Ability, And Academic Performance In Young Adults
The goal of this study is to determine the effect of resistance training on physical fitness, cognitive ability, and academic performance in young adults.
- Trial name
- NCT06086808
- Testing
- Resistance Training, General Fitness and Toning
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Marijuana Dependence
Sex Differences in Attentional Bias in Marijuana-dependent Individuals
The purpose of this study is to explore sex differences in cognitive functioning and responses to marijuana-related items, and to determine whether stress impacts these measures.
- Trial name
- NCT01179425
- Testing
- Cognitive stressor
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Cannabis Use, Neurocognitive Dysfunction
Prospective Evaluation on Cognitive Function and Its Associated Genetic Vulnerability in Cannabis Users
Most of the studies assessing Cannabis Use Disorder (CUD) and neurocognitive functions are cross-sectional without examining the longitudinal changes in neurocognitive function at a within-subject level with respect to the…
- Conditions
- Cannabis Use, Neurocognitive Dysfunction, Genetic Predisposition
- Trial name
- SToP-C_PeCoG (NCT04373525)
- Testing
- Genome analysis
- Where
- Hong Kong
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong